• BMB Reports
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• v.29 no.4
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• pp.380-385
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• 1996

Ovomucoid third domain is a serine proteinase inhibitor protein which consists of 56 amino acid residues. A fifty picosecond molecular dynamics (MD) simulation was carried out for ovomucoid third domain protein with 5 $\AA$ layer of water molecules. A comparison of main chain atoms in the MD averaged structure with the crystal structure showed that most of the backbone structures are maintained during the simulation. Investigation of the intramolecular hydrogen bondings indicated that most of the interactions between main chain atoms were conserved, whereas those between side chains were reorganized for the period of the simulation. Especially, the side chain interactions around the scissile bond of reactive site P1 (Met18) were found to be more extensive for the MD structures. During the simulation, hydrogen bonds were maintained between the side chains of Glu19 and Arg21 as well as those of Thr17 and Glu19. Extensive side chain interactions observed in the MD structures may shed light on the question of why protein proteinase inhibitors are strong inhibitors for proteinases rather than good substrates.

• Proceeding of EDISON Challenge
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• 2017.03a
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• pp.95-99
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• 2017

Protein contact map은 단백질 삼차구조에 대한 정보를 이차원의 이미지로 표현하는 방법의 하나로, 비교적 간략하지만 단백질 구조에 대한 핵심적 정보를 함축하고 있다. 이러한 단백질 구조를 바탕으로 단백질의 internal energy, solvation free energy, free energy 와 같은 열역학 함수를 도출할 수 있다. 본 연구에서는 이미지 인식에 대한 머신러닝 기법을 사용하여 단백질 구조를 함축하는 단백질의 contact map으로부터 단백질의 열역학적 함수를 예측하는 연구를 진행하였다. 단백질의 main-chain 간의 contact map, side-chain 간의 contact map, main-chain과 side-chain 간의 contact map 들로부터 단백질의 여러 가지 열역학적 함수를 예측하고자 했으며 최종적으로 Convolution Neural Network (CNN) 기법을 사용하여 단백질의 free energy를 ~18 kcal/mol의 범위에서 예측 가능함을 보였다. 본 연구를 바탕으로 단백질의 contact map과 열역학 함수 사이의 상관관계가 있으며, 머신러닝 기법을 사용하여 단백질 contact map으로부터 열역학적 함수를 예측하는 것이 가능함을 보였다.

• Journal of the Korean Wood Science and Technology
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• v.10 no.2
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• pp.12-21
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• 1982

Red pine and Japanese larch (Larix leptolepis Gordon) grown in Korea have been the main species of coniferous resources in Korea. Especially, planting area of Japanese larch has been increased continueously in the recent years due to its superior plant type and rapid growth rate and its stocks reached approximately 4.32 million cubic meters at the present time. Although many research works have been done for the utilization of the larch wood in various ways, still many problems are existed in its chemical applications due to a large proportion of soluble extractives. In this study, chemical composition of larch extractives and chemical structure of its major component were analyzed. In order to identify the basic structure of major component, gas-liquid chromatography for separation of some completely methylated alditols as their acetates on a 3% - ECNSS-M on Gas Chrom Q. column was used. Proportion of extractives of Japanese larch wood was higher than that of other conifers and major component of the soluble extractives was arabinogalactan, a schematic structural formula which was presented in Figure 2. The molar ratio of arabinose and galactose was 1:4.5. The main chain of arabinogalactan was composed of 1,3 linked ${\beta}$-D-galactopyranose residues, each of which carried a side chain, attached to the C-6 positions. The exact nature of all of the side chains is not known, but the majority of these side chain was composed of 1, 6 linked ${\beta}$-D-galactopyranose residues, with 2~3 such units present per average chain. Some of the galactose units in the main chain had a residue of 3 - 0 - ${\beta}$-L-arabinopyranosyl-L-arabinofuranose. In addition, a few terminal residues of D-glucuronic acid also was confirmed, attached to C-6 position of the D-galactopyranose residue. It could concluded that the main structure of highly branched arabinogalactan from Japanese larch extractive was essentially the same as those of the other larch species.

• 한국정보디스플레이학회:학술대회논문집
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• 2003.07a
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• pp.937-939
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• 2003

We synthesized and characterized new fluorene-based polyquinoxalines with ether-linkage in the main chain, which have luminescent properties. Cyclic voltammetry reveals that these polymers have a low-lying LUMO and HOMO energy levels. Therefore, the polymers would be attractive candidates for electron-tansporting or hole-blocking materials in LEDs.

• Journal of the Korean Society of Clothing and Textiles
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• v.34 no.1
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• pp.1-13
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• 2010

This study analyzes the innovation process of the value chain in the fashion industry. It examines the differences between traditional and FF-based methods that include value chain processes such as design, production, and distribution-sales process. In the literature review and case studies, general propositions were drawn from each innovative stage by a comparison analysis. First, design speed is the main factor to explain the impact of IT in the design process. Second, small quantity batch production becomes main stream by the adoption of a computer-integrated manufacturing system in the production process. Third, cost reduction and speedup improvement are results of innovation in the distribution process. Last, a customized interface provides important information that can integrate the value chain and make useful customer relationships in the sales process. Fast fashion is the best product of these procedural innovations in the overall value chain. Consequently, this study confirmed that the general propositions referred above were acceptable and adaptable in the case of ZARA in terms of fast fashion strategy.

• The Journal of Information Systems
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• v.24 no.4
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• pp.43-60
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• 2015

Purpose This study intended to introduce new approaches to identify the intellectual structure of supply chain management(SCM) researches, which combines author co-citation analysis(ACA) and social network analysis(SNA). Design/methodology/approach We searched RISS(www.riss.kr) and NDSL(www.ndsl.or.kr) database and collected 292 academic papers on supply chain management between 2001 and 2011. Among 9,637 references of these papers, we analyzed 1,848 references that were published by domestic authors. We produced a correlation matrix of 32 author co-citation matrix and conducted multi-variate statistical analysis such as factor analysis. We also performed social network analysis to identify the main researchers in SCM. Findings We found four main sub-areas of supply chain management research: SCM adoption factors, logistics, SCM performance, and SCM structure. We could present the authors who played important roles within the network by using SNA indicators. The finding of this research also suggests more collaborations among domestic researchers are required to overcome the low co-citation rates among domestic authors.

• Transactions of the Korean Society of Automotive Engineers
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• v.25 no.2
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• pp.133-139
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• 2017

The timing chain system, which is a typical power transmission technology applied to a vehicle, has been widely used by the automotive industry because it is normally designed to last a car's lifetime. However, the timing chain system may cause some problems due to the shape of the chains and the polygonal behavior on contact between the chain and the sprocket. In addition, noise and vibration caused by transmission error are the most typical problems encountered by major automotive manufacturers and they are considered as the main source of customer complaint. The initial tension of the chain-sprocket system is thought to be the main cause of transmission error, and it is regarded as the source of engine vibration and noise. The initial tension of the chain system should be controlled carefully since a low initial tension can cause twisting, which may lead to a system malfunction, while a high initial tension can reduce the service life due to a worn down contact surface. In this paper, the kinematic analysis model is generated with various initial tensions, which are controlled by changing the shape of the fixed guide with the largest contact surface with chain. The results showed that the transmission error was minimized on a particular range of initial tension, and the tendency showed that the error changed with a higher sensitivity at a lower initial tension.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2000.04b
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• pp.143-146
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• 2000

We studied effects of alkyl($C_nH_{2n+1}$) chain length on characteristics of poly(3-alkylthiophene) electroluminescent diodes. Among the poly(3-alkylthiophene), poly(3-hexylthiophene)(n=6) and poly(3- octyIthiophene)(n=8) were mainly used for the emitting layer of the diode. The result of experiment, the emission intensity of poly(3-alkylthiophene) electroluminescent diodes depends on the alkyl chain length. Strong emission is obtained from a poly(3-alkylthiophene) diodes of long alkyl side chain length. Emission intensities are enhanced by a confinement of carriers on a main chain with a long interchain distance caused by a long alkyl side chain.

• The Korean Journal of Ecology
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• v.21 no.1
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• pp.105-112
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• 1998

Characteristics of species distribution in the Baekdoo Great Mountain Chain of Kangwon Province were discussed. Resulting from Detrending Correspondence Analysis based on the floristic composition of 48 mountains, the mountains of the Baekdoo chain tended to aggregate on DCA axis. it represented that there was the peculiar floristic composition of the Baekdoo chain separated from the other mountains. High altitude, longitude near the East Sea and large number of vascular species were main factors for the distribution pattern. And exponential relationships between endemic rare species and number of species were clarified. Even though the regions of the Baekdoo Great Mountain Chain had been conserved relatively well, many regions have been faced to be disturbed for tourism, agriculture, forestry, livestock industry and mining since the local autonomy. Thusm, the necessity for the establishment of large area network through the connection of scattered protected areas in the Baekdoo Great Mountain Chain was suggested. it would play a role as a core of nature conservation to sustain species diversity in Korea.

• Journal of the Korea Safety Management & Science
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• v.17 no.2
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• pp.191-199
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• 2015

Considering the supply system and operating cost of enterprises which are in the supply chain as the main index, this paper establishes a supply chain evaluation model, and utilizes Arena building stimulation model of the supply chain which considers manufacturing enterprises as the core of supply chain. This model designs a generic simulation model of the supply chain including multi-level distributors and suppliers. And the model analyzes a representative example of business process, one of the enterprises in Shandong.