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A Study on the thermal analysis techmique in concrete structures by F.E.M (유한요소법을 이용한 콘크리트구조물내의 온도분포해석 기법에 관한 연구)

  • 오병환;이명규
    • Proceedings of the Korea Concrete Institute Conference
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    • 1993.04a
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    • pp.213-218
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    • 1993
  • F.E.M formulation is carried out in order to determine temperature distribution in the concrete structure. According to this formulation an F.E.M. code is developed, which is capable of silmulating time varying boundary conditions and nonlinear thermal properties.

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Analysis of Wide-gap Semiconductors with Superconducting XAFS Apparatus

  • Shiki, S.;Zen, N.;Matsubayashi, N.;Koike, M.;Ukibe, M.;Kitajima, Y.;Nagamachi, S.;Ohkubo, M.
    • Progress in Superconductivity
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    • v.14 no.2
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    • pp.99-101
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    • 2012
  • Fluorescent yield X-ray absorption fine structure (XAFS) spectroscopy is useful for analyzing local structure of specific elements in matrices. We developed an XAFS apparatus with a 100-pixel superconducting tunnel junction (STJ) detector array with a high sensitivity and a high resolution for light-element dopants in wide-gap semiconductors. An STJ detector has a pixel size of $100{\mu}m$ square, and an asymmetric layer structure of Nb(300 nm)-Al(70 nm)/AlOx/Al(70 nm)-Nb(50 nm). The 100-pixel STJ array has an effective area of $1mm^2$. The XAFS apparatus with the STJ array detector was installed in BL-11A of High Energy Accelerator Research Organization, Photon Factory (KEK PF). Fluorescent X-ray spectrum for boron nitride showed that the average energy resolution of the 100-pixels is 12 eV in full width half maximum for the N-K line, and The C-K and N-K lines are separated without peak tail overlap. We analyzed the N dopant atoms implanted into 4H-SiC substrates at a dose of 300 ppm in a 200 nm-thick surface layer. From a comparison between measured X-ray Absorption Near Edge Structure (XANES) spectra and ab initio FEFF calculations, it has been revealed that the N atoms substitute for the C site of the SiC lattice.

Dynamics of Forest Community Structure at the Valley of Piagol and Daeseonggol in the Jirisan National Park(I) (지리산국립공원 피아골과 대성골 지역의 산림군집구조 동태(I))

  • Oh, Koo-Kyoon;Kim, Yong-Shik;Oh, Jang-Guen;Ki, Young-Bum
    • Korean Journal of Environment and Ecology
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    • v.22 no.5
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    • pp.514-520
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    • 2008
  • The permanent monitoring plots were installed in 2001 for long-term monitoring the structure of forest communities at the Piagol(Valley) and Daeseonggol(Valley) in the Jirisan National Park, and monitored the forest structure in the studied sites in 2001 and 2006. Dominant species at Piagol and Daeseonggol was Carpinuslaxiflora and Quercus mongolica respectively. Based on the distribution of major species' stem diameter, the species diversity index was higher in Piagol than that of Daeseonggol. The distribution of diameter in major tree species in the studied sites showed a stable plant community structure. The forest of Piagol, which is positioned in the valley, showed a quite a different composition of species from that of Daeseonggol, which is positioned on the slope. In the last five years, the overall grows rate of Piagol Forest decreased by $6.4m^2$ per hectare, while Daeseonggol Forest increased by about $8.27m^2$ per hectare. I think that this is because of the fact that a lot of large old trees have died.

Discovery of Cyclin-dependent Kinase Inhibitor, CR229, Using Structure-based Drug Screening

  • Kim, Min-Kyoung;Min, Jae-Ki;Choi, Bu-Young;Lim, Hae-Young;Cho, Youl-Hee;Lee, Chul-Hoon
    • Journal of Microbiology and Biotechnology
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    • v.17 no.10
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    • pp.1712-1716
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    • 2007
  • To generate new scaffold candidates as highly selective and potent cyelin-dependent kinase (CDK) inhibitors, structure-based drug screening was performed utilizing 3D pharmacophore conformations of known potent inhibitors. As a result, CR229 (6-bromo-2,3,4,9-tetrahydro-carbolin-1-one) was generated as the hit-compound. A computational docking study using the X-ray crystallographic structure of CDK2 in complex with CR229 was evaluated. This predicted binding mode study of CR229 with CDK2 demonstrated that CR229 interacted effectively with the Leu83 and Glu81 residues in the ATP-binding pocket of CDK2 for the possible hydrogen bond formation. Furthermore, biochemical studies on inhibitory effects of CR229 on various kinases in the human cervical cancer HeLa cells demonstrated that CR229 was a potent inhibitor of CDK2 ($IC_{50}:\;3\;{\mu}M$), CDKI ($IC_{50}:\;4.9\;{\mu}M$), and CDK4 ($IC_{50}:\;3\;{\mu}M$), yet had much less inhibitory effect ($IC_{50}:>20\;{\mu}M$) on other kinases, such as casein kinase 2-${\alpha}1$ (CK2-${\alpha}1$), protein kinase A (PKA), and protein kinase C (PKC). Accordingly, these data demonstrate that CR229 is a potent CDK inhibitor with anticancer efficacy.

Effect of Thermal Stratification and Mixing on Phytoplankton Community Structure in the Western Channel of the Korea Strait

  • Shon, Dong-Hyun;Shin, Kyoung-Soon;Jang, Pung-Guk;Kim, Young-Ok;Chang, Man;Kim, Woong-Seo
    • Ocean and Polar Research
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    • v.30 no.3
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    • pp.261-275
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    • 2008
  • The profile of a fixed site at station M ($34.77^{\circ}N,\;129.13^{\circ}E$) in the Korea Strait was studied from March 2006 to February 2007. The aim was to understand the relationship between the annual thermal stratification pattern and seasonal variation in phytoplankton community structure. Physicochemical factors including temperature, salinity and nutrient concentrations, which strongly influence the proliferation and diversity of phytoplankton, were measured. The study period was divided into three due to the characteristic of thermohaline structures; mixed I (March-May 2006), stratified (June-November 2006) and mixed II(December 2006-Feburuary 2007). Diatoms dominated during the mixed I (89%) and II (48%) periods, while nanoplankton group occupied over 83% of total population during the stratified period. The dominant species during the mixed I and II was Chaetoceros socialis (47% and 29%, respectively), while during the stratified period Gyrodinium sp.(4%) was the most dominant. Averaged total chl a concentrations during the mixed I and II periods were 0.61 mg $m^{-3}$ and 0.72 mg $m^{-3}$, respectively, which were at least two-fold higher than that during the stratified period (0.30 mg $m^{-3}$). The vertical mixing and convection process of the water column induced nutrient supply from the bottom layer to the euphotic zone. It also led to the dominance of diatoms during the mixed periods, whereas small phytoplankton prevailed over large phytoplankton as stratification blocked the upward movement of nutrients to subsurface during the stratified period. During the mixed I and II periods, microplanktonic chl a dominated concentrations (50% and 48%, respectively), while picoplanktonic chl a occupied over 37% of total chl a during the stratified period.

The Preliminary Study on the Structure of Cop Protein by CD and NMR

  • Kim, Yun-Kyong;Park, Sang-Ho;Lee, Jee-Hyun;Kwak, Jin-Hwan;Lee, Bong-Jin
    • Journal of the Korean Magnetic Resonance Society
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    • v.3 no.2
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    • pp.100-108
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    • 1999
  • Cop protein is the transcription repressor protein in rolling circle replication plasmid. With antisense RNA, Cop protein controls the copy number of plasmid. Cop family proteins have been found in various plasmids. Among Cop family proteins, Cop studied in this paper consists of 55 amino acids (Mw. 6,400), and was known to have trimer structure. Since no structural facts are elucidated, we have carried out preliminary experiments aimed at the elucidation of its three dimensional structure. The secondary structure of Cop is studied by CD and NMR. To solve the aggregation of Cop at high concentration, we tested various detergents and salts. The addition of detergents and salts could not solve the aggregation problem. However, we found that concentration is important in solving the aggregation problem. We knew that 0.18mM in 50mM potassium phosphate without any other ingredients is maximum concentration not to aggregate. Wa also investigated the pH dependence of Cop protein, and knew that Cop protein is more stable in acid state. At various temperatures, 15N-1H HSQC spectra were measured in order to find the optimal experimental condition. To enhance the peak resolution, 3D NOESY-HSQC spectrum is acquired. Since there are NOE peaks in the NH-NH region, we knew that Cop protein has $\alpha$-helical content, which was also confirmed by CD.

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Edge Vegetation Structure in the Chirisan National Park (지리산 국립공원의 주연부 식생구조)

  • 오구균;권태호;이규완
    • Korean Journal of Environment and Ecology
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    • v.5 no.1
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    • pp.68-78
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    • 1991
  • To investigate edge vegetation structure and species in the Chrisan National Park, filed survey was excuted from August to October, 1991 and the results were as follows. Importance values of species in lower layer were changed according to the distance from edge to forest interior at the northeastern slope of a highland. Change of vegetation structure was observed from edge up to 30m of forest interior and edge depth was estimated as 15~20m. The dominance and frequency of edge species seemed to be affected by the factors of altitude, aspect and topographic location. Especially, edge vegetation showed severe difference according to topographic location between a ridge and a foot of a mountain, and according to aspect between southern and northern slope above midslope region of a mountain. Comparing vegetation structure of lower layer for southern and northern slope, more no. of individuals and crown coverage were observed at northern slope, while more no. of species, species diversity and coverage of Sasa purpurascen at southern slope.

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Optimizing Image Size of Convolutional Neural Networks for Producing Remote Sensing-based Thematic Map

  • Jo, Hyun-Woo;Kim, Ji-Won;Lim, Chul-Hee;Song, Chol-Ho;Lee, Woo-Kyun
    • Korean Journal of Remote Sensing
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    • v.34 no.4
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    • pp.661-670
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    • 2018
  • This study aims to develop a methodology of convolutional neural networks (CNNs) to produce thematic maps from remote sensing data. Optimizing the image size for CNNs was studied, since the size of the image affects to accuracy, working as hyper-parameter. The selected study area is Mt. Ung, located in Dangjin-si, Chungcheongnam-do, South Korea, consisting of both coniferous forest and deciduous forest. Spatial structure analysis and the classification of forest type using CNNs was carried in the study area at a diverse range of scales. As a result of the spatial structure analysis, it was found that the local variance (LV) was high, in the range of 7.65 m to 18.87 m, meaning that the size of objects in the image is likely to be with in this range. As a result of the classification, the image measuring 15.81 m, belonging to the range with highest LV values, had the highest classification accuracy of 85.09%. Also, there was a positive correlation between LV and the accuracy in the range under 15.81 m, which was judged to be the optimal image size. Therefore, the trial and error selection of the optimum image size could be minimized by choosing the result of the spatial structure analysis as the starting point. This study estimated the optimal image size for CNNs using spatial structure analysis and found that this can be used to promote the application of deep-learning in remote sensing.