• Title/Summary/Keyword: lung density

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Effects of Kimchi Powder or Lactobacillus plantarum Added Fermented Sausages on Serum Lipid and Cholesterol Levels in Rats

  • Lee, Jin-Wook;Pyun, Chang-Won;Hong, Go-Eun;Han, Kyu-Ho;Choi, Kang-Duk;Lee, Chi-Ho
    • Food Science of Animal Resources
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    • v.33 no.4
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    • pp.435-438
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    • 2013
  • This study was performed to investigate the serum lipid and cholesterol lowering effects of kimchi powder or Lactobacillus plantarum when added to fermented sausage in rats. Male SD (Sprague-Dawley) rats were divided in three groups and administered with the following diets for 6 wk: non-fermented sausage added diets (CON), kimchi fermented sausage added diets (KIM), and Lactobacillus plantarum fermented sausage added diets (PLA). The CON has significantly (p<0.05) higher food intake, body weight gains, and final body weight than the other two groups. The body weight of KIM was significantly (p<0.05) lower than that of the other groups. The weights of organs (heart, lung, liver, kidney, spleen, perirenal adipose tissue, and epididymal adipose tissue) were not affected by any treatments. The mean value of serum triglycerides (TG) concentration in KIM and PLA groups was not significantly different compared with CON. Total cholesterol, low density lipoprotein and high density lipoprotein levels in serum of KIM were significantly (p<0.05) lower than those of CON. The serum free cholesterol level and atherogenic index (AI) in KIM and PLA were significantly (p<0.05) lower than those of CON. In conclusion, dietary supplementations with kimchi powder fermented sausages or L. plantarum fermented sausages were effective for lowering serum lipid, cholesterol levels and atherogenic index in rats.

Analytical Variability of Airborne Man-made Mineral Fibers by Phase Contrast Microscopy (위상차 현미경법에 의한 인조광물섬유 분석 변이)

  • Shin, Yong Chul;Yi, Gwang Yong;Kim, Boowook
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.22 no.2
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    • pp.134-139
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    • 2012
  • Objectives: This study was conducted to study the analytical variability of A & B counting rules in counting using a phase contrast microscope airborne fibers collected on filters in man-made mineral or vitreous fibers (MMMFs) industries. Methods: Fibers in filters were counted using A & B rules of NIOSH Method 7400. Intra-counter and inter-counter variations by fiber type and density were obtained. The types of MMMFs analyzed were glass wool fiber, rock wool fiber, slag wool fiber, and refractory ceramic fibers. The densities of fibers classified were <20 $fibers/mm^2,$ 20 - <50 $fibers/mm^2$, 50 - <100 $fibers/mm^2,$ and ${\geq}100$ $fibers/mm^2,$ respectively. Results: Intra-counter relative standard deviations by rule A were 0.084, 0.102, 0.071 for glass wool fibers, rock wool fibers and refractory ceramic fibers, and those by rule B were 0.139, 0.120 and 0.142, respectively. Inter-counter relative standard deviations by rule A were 0.281, 0.296, 0.180 for glass wool fibers, rock wool fibers and refractory ceramic fibers, and those by rule B were 0.396, 0.337 and 0.238, respectively. Conclusions: Intra-counter variation was not different significantly among fiber types (p>0.05), but B rule variation for ceramic fibers approximately 2 times greater than corresponding A rule estimates, and intra-counter and inter-counter variations were higher in the low fiber density.

Effects of Crormakalim on the Release of Mediators in Hypersensitivity of Guinea pig (Cromakalim이 해명의 과민반응 매개체 유리에 미치는 영향)

  • Ro, Jai-Youl;Kim, Kyung-Hwan
    • The Korean Journal of Pharmacology
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    • v.29 no.2
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    • pp.263-274
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    • 1993
  • Potassium $(K^+)$ channels are present in airway smooth muscle cells, and their activation results in hyperpolarization and relaxation. Because these effects may have therapeutic relevance to hypersensitivity and asthma, we examined the effect of a potassium channel activator, cromakalim (BRL 34915, CK) on the release of mediators from superfused tracheal and parenchymal strips after passive sensitization with $IgG_1$ antibody. Both tissues were superfused with CK $(2{\times}10^{-6}\;M)$ for 30 min and challenged with CK and antigen (Ox-HSA). Using monodispersed, partially purified, highly purified guinea pig lung mast cells, we also examined the effect of CK on mediator release from these cells after passive sensitization with $IgG_{1}$ antibody $({\alpha}-OA)$. Guinea pig lung mast cells were purified using enzyme digestion method, count current elutriation, and discontinuous Percoll density gradient. After CK pretreatment, passively sensitized mast cells were challenged with varying concentration of antigen (OA, immunological stimuli) or with varying concentration of calcium ionophore (CaI, non-immunological stimuli). Histamine (Hist) release was determined by spectrophotofluorometry, and leukotrienes (LT) by radioimmunoassy. CK pretreatment decreased Hist by 35% and LT release by 40% in the antigen-induced tracheal tissue after $IgG_1$ sensitization but did not decrease the contractile response. In the antigen-induced parenchymal tissue CK decreased Hist release by 25% but poorly decreased LT. Both immunologic and non-immunologic stimuli caused a dose-dependent release of Hist and LT from monodispersed, partially purified and highly purified lung mast cells. Verification of LT release was obtained by the use of 5-lipoxygenase inhibitor, A64077 (Zileuton). CK decreased Hist and LT release by 20% respectively in the OA-induced guinea pig lung mast cells after $IgG_1$ sensitization. The inhibitory effects of CK on the Hist and LT release in the Ox-HSA-induced airway smooth muscle tissues or in the OA-induced and CaI-induced mast cells after $IgG_1$ sensitization were completely blocked by TEA and GBC. These studies show that guinea pig lung mast cells seem to be an important contributor to LT release, and that CK (which has been known as an airway smooth muscle relaxant) can in part act to inhibit mediator release in the antigen-induced airway smooth muscle, and that CK may also act to inhibit mediator release in the OA-induced and CaI-induced highly purified mast cells. These results suggest that Hist and LT release evoked by mast cell activation might in part be associated with $K{^+}4 channel activity.

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Surgical Treatment of Traumatic Ventricular Septal Defect by Penetrating Chest Injury (흉부관통상으로 인한 심실중격결손의 치료)

  • 김시욱;한종희;강민웅;나명훈;임승평;이영;최시완;유재현
    • Journal of Chest Surgery
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    • v.37 no.12
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    • pp.999-1002
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    • 2004
  • Thirteen year old boy who had been stabbed in his left chest by the knife was transferred to our department from a general hospital, because of the massive bleeding from the intercostal tube drainage. Chest X-ray showed homogeneous density in the left lung field. He was confused and his vital signs were unstable. He was moved into a operating room as soon as possible. After resuscitation, his lacerated left ventricle wound was sutured through median sternotomy. The interventricular shunt was detected with intraoperative transesophageal echocardiography. The traumatic ventricular septal defect was closed via left ventricle using Dacron patch. His postoperative course was uneventful, and he was discharged with small residual shunt.

Current Status of Health Screening in Korea (한국의 건강검진 현황)

  • Jo, Han-Ik
    • Journal of Korea Association of Health Promotion
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    • v.2 no.3
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    • pp.73-96
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    • 2004
  • Along with a development of medical technology, a variety of tests, such as laboratory tests, x-ray and endoscopies are being used in health screening tests. As the tests determine the quality of health screening, test items and methods should be carefully selected. This study was to get hold of the test items of major health screening programs in Korea Most of the health screening programmes focused upon detection of risk factors and diagnosis of life - style related diseases (diabetes, hypertension, cardiovascular diseases, hypercholesterolemia, overweight, drinking, smoking, cerebrovascular diseases, osteoporosis) ,cancers (stomach, cervix, lung, breast, liver, colon, prostate, ovary, pancreas, thyroid, esophagus) , infectious diseases (hepatitis, tuberculosis, sexually-transmitted diseases, parasites) , chronic obstructive respiratory diseases, chronic renal diseases (bacteriuria hematuria, proteinuria) , anemia, glaucoma, hearing loss, Alzheimer disease, stress, early psychiatric diseases. The health screening tests were basic physical examination, basic laboratory tests (CBC, urinalysis, liver function tests, lipid tests, glucose, HbAlc, uric acid, electrolytes, serological tests (HBsAg, HBs-Ab, HCV-Ab, HIV-Ab, VDRL) EKG, x-ray (chest PA, CT) , endoscopy (gastroscopy, colonoscopy) , sonography(abdomen, thyroid, pelvis, breast) ,cytology (cervix) , bone density, tumor markets (NMP22, alpha-FP, CEA, CA-19-9, CA12S, PSA) and eye tests. Advanced technologies, like CT, PET, MRI, MRT/Angio, molecular testings) were widely used in hospital health screening programmes .In summary, a variety of tests were utilized in health screening in Korea. Those tests were utilized by stages or according to sex and age in most of health screening programmes, however a few program used tests to excess disregarding health screening subjects.

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Mass Outbreak of Hypervitaminosis A in Foxes after Prolonged Feeding of Pig Liver (여우에 있어서 돼지 간 급여에 의한 비타민 A 과잉증의 집단발생)

  • Lee Chang-Woo;Bak Ung-Bok;Sung Jai-Ki;Kweon Oh-Kyeong;Lee Kyoung-Kap;Jung Young-Tane;H. Matsumoto
    • Journal of Veterinary Clinics
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    • v.8 no.1
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    • pp.119-125
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    • 1991
  • Hypervitaminosis A occurred in about 30% of foxes of five farms in Choongcheongbukdo-province from October 1989 to February 1990. Clinical signs were loss of appetite, retarded growth, lameness. Radiological changes were decreased density of the long bones, especially fibula, and osteophytes developed either on the lateral condyle of humerus or ulnar just below the semilunar notch. Pathological change was the development of exotosis as is evidenced by radiological examination. Pig liver and lung consisted 30∼55% of feeds from March 1989 to February 1990. The serum concentrations of vitamin A in 2 affected foxes were 45,900 and 47,300 IU/d$\ell$ and the concentrations of vitamin A in the liver were 8,760 and 10,842 IU/gm respectively. It is concluded that the high level of vitamin A in the pig liver and the large amount of pig liver in the feed composition are the etiology of the disease.

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국내 주요 기관의 건강진단 검사 종목

  • Jo, Han-Ik;Kim, Sang-In
    • Journal of Korea Association of Health Promotion
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    • v.2 no.1
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    • pp.9-25
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    • 2004
  • Along with a development of medical technology, a variety of tests, such as laboratory tests, x-ray and endoscopies are being used in health screening tests. As the tests determine the quality of health screening, test items of major health screening program in Korea. Most, of the health screening programmes focused upon detection of risk factors and diagnosis of life-style related diseases(diabetes, hypertension, cardiovascular diseases, hypercholesterolemia, overweight, drinking, smoking, cerebrovascular diseases, osteoporosis), cancers(stomach, cervix, lung, breast, liver, colon, prostate, ovary, pancreas, thyroid, esophagus), infections diseases(hepatitis, tuberculosis, sexually-transmitted diseases, parasites), chronic obstructive respiratory diseases, chronic renal diseases(bacteriuria, hematuria, proteinuria), anemia, glaucoma, hearing loss, Alzheimer disease, stress and earlypsychiatric diseases. The health screening tests were basic physical examination, basic laboratory tests( CBC, urinalysis, liver function tests, lipid tests, glucose, HbA1c, uric acid, electrolytes, serological tests(HBsAg, HBs-Ab, HCV-Ab, HIV-Ab, VDRL) EKG, x-ray(chest PA, CT) endoscopy(gastroscopy, colonoscopy), sonography (abdomen, thyroid, pelvis, breast), cytology(cervix), bone density, tumor markers(NMP22, alpha-FP, CEA, CA-19-9, CA125, PSA and eye tests. Advanced technologies, like CT, PET, MRI, MRI/Angio, molecular testing were widly used in hospital based health screening programmes. In summary, a variety of tests were untilized in health screening in Korea. Those tests were utilized by stages or according to sex and age in most of health screening programmes, however a few programs used tests excessvely disregarding health screening subjects.

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Idiopathic Hypertrophic Cranial Pachymeningitis Misdiagnosed as Acute Subtentorial Hematoma

  • Park, Ik-Seong;Kim, Hoon;Chung, Eun-Yong;Cho, Kwang-Wook
    • Journal of Korean Neurosurgical Society
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    • v.48 no.2
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    • pp.181-184
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    • 2010
  • A case of idiopathic hypertrophic cranial pachymeningitis (IHCP) misdiagnosed as an acute subdural hematoma is reported. A 37-year-old male patient presented with headache following head trauma 2 weeks earlier. Computerized tomography showed a diffuse high-density lesion along the left tentorium and falx cerebri. Initial chest X-rays revealed a small mass in the right upper lobe with right lower pleural thickening, which suggested lung cancer, such as an adenoma or mediastinal metastasis. During conservative treatment under the diagnosis of a subdural hematoma, left cranial nerve palsies were developed (3rd and 6th), followed by scleritis and uveitis involving both eyes. Magnetic resonance imaging (MRI) revealed an unusual tentorium-falx enhancement on gadolinium-enhanced T1-weighted images. Non-specific chronic inflammation of the pachymeninges was noticed on histopathologic examination following an open biopsy. Systemic steroid treatment was initiated, resulting in dramatic improvement of symptoms. A follow-up brain MRI showed total resolution of the lesion 2 months after steroid treatment. IHCP should be included in the differential diagnosis of subtentorial-enhancing lesions.

Evaluation of Chest Density in Insight Film (Insight film을 이용한 농도측정 평가)

  • Kwon, Lee-Seon;Park, Jang-Hwan;Lim, Oh-Soo;Jung, Kyong-Mo;Cheung, Hwan
    • Journal of radiological science and technology
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    • v.15 no.2
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    • pp.17-23
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    • 1992
  • Simple chest radiography is the most frequently performed examination in radiologic practice. However, with transmitted dose through chest which has the problem of wide variations in absorption, conventional Film/Screen Combinations Method make it difficult to delineate lung field mediastinum & cardia portion and subdiaphragmatic structures. In order to overcome this problem, we have been tried several methods as follows. High Kilovoltage Technique, Rare Earth Screen/Wide Lattitude Film, Use of Compensating Filter and Digital Beam Attenuator and recently Insigh System has been developed. In this paper, we'd like to discuss Insight film through apperciation by measuring the difference of contrast. In order to evaluate insight film. We have done experiments using Insight System with Simple Phase, Picker 550. We could get an result which was able to overcome the limitted dynamic range of conventional Film/Screen System remarkably.

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Electrorhelological Properties of Monodispersed Submicron-sized Hollow Polyaniline Adipate Suspension

  • Sung, Bo-Hyun;Choi, Ung-Su
    • KSTLE International Journal
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    • v.6 no.1
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    • pp.28-32
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    • 2005
  • The electrorheoloRical (ER) fluids are composed of a colloidal dispersion of polarizable particles in insulating oil, and it's the rheological property changes by the applied electric field. These changed are reversible and occur fast within a fewmilliseconds. The ER properties of the ER fluid such as increment of viscosity and yield stress come from the particle chain structure induced by electric fleld. When formulating the ER fluid for a speciflc application, some requirement must besatisfled, which are high yield stress under electric field, rapid response, and dispersion stability. While this characteristic makes valuable ER fluids in valious industrial applications, their lung term and quiescent application has been limited because ofproblems with particle sedimentation. In an effort to overcome sedimentation problem of ER fluids, the anhydrous ER materials of monodispersed hollow polyaniline (PANI) and adipate derivative respectively with submicron-sized suspension providing wide operating temperature range and other advantage were synthesized in a four-step procedure. The ER fluidswere characterized by FT-lR, TGA, DLS, SEM, and TEM. Stability of the suspensions was examined by an UV spectroscopy.The rheological and electrical properties of the suspension were investigated Couette-type rheometer with a high voltagegenerator, current density, and conductivity. And the behavior of ER suspensions was observed by a video camera attached toan optical microscope under 3kV/mm. The suspensions showed good ER properties, durability, and particle dispersion.