• Title/Summary/Keyword: low-dose

Search Result 2,905, Processing Time 0.04 seconds

A review of two theories of motion sickness and their implications for tall building motion sway

  • Walton, D.;Lamb, S.;Kwok, Kenny C.S.
    • Wind and Structures
    • /
    • v.14 no.6
    • /
    • pp.499-515
    • /
    • 2011
  • Low-frequency building vibration is known to induce symptoms of motion sickness in some occupants. This paper examines how the adoption of a theory of motion sickness, in conjunction with a dose-response model might inform the real-world problem of managing and designing standards for tall building motion sway. Building designers require an understanding of human responses to low-dosage motion that is not adequately considered by research into motion sickness. The traditional framework of Sensory Conflict Theory is contrasted with Postural Instability Theory. The most severe responses to motion (i.e., vomiting) are not experienced by occupants of wind-excited buildings. It is predicted that typical response sets to low-dosage motion (sleepiness and fatigue), which has not previously been measured in occupants of tall-buildings, are experienced by building occupants. These low-dose symptoms may either be masked from observation by the activity of occupants or misattributed to the demands of a typical working day. An investigation of the real-world relationship between building motion and the observation of low-dose motion sickness symptoms and a degradation of workplace performance would quantify these effects and reveal whether a greater focus on designing for occupant comfort is needed.

Absorbed and effective dose from spiral and computed tomography for the dental implant planning (치과 임프란트 치료 계획을 위한 나선형 일반 단층촬영과 전산화 단층촬영시 흡수선량 및 유효선량 평가)

  • Hong Beong-Hee;Han Won-Jeong;Kim Eun-Kyung
    • Imaging Science in Dentistry
    • /
    • v.31 no.3
    • /
    • pp.165-173
    • /
    • 2001
  • Objectives : To evaluate the absorbed and effective doses of spiral and computed tomography for the dental implant planning. Materials and Methods: For radiographic projection, TLD chips were placed in 22 sites of humanoid phantom to record the exposure to skin and the mean absorbed dose to bone marrow, thyroid, pituitary, parotid and submandibular glands and nesophagus. Effective dose was calculated, using the method suggested by Frederiksen et al.. Patient situations of a single tooth gap in upper and lower midline region, edentulous maxilla and mandible were simulated for spiral tomography. 35 axial slices (maxilla) and 40 axial slices (mandible) with low and standard dose setting were used for computed tomography. All the radiographic procedures were repeated three times. Results: The mean effective dose in case of maxilla was 0.865 mSv, 0.452 mSv, 0.136 mSv and 0.025 mSv, in spiral tomography of complete edentulous maxilla, computed tomography with standard mAs, computed tomography with low mAs and spiral tomography of a single tooth gap (p<0.05). That in case of mandible was 0.614 mSv, 0.448 mSv, 0.137 mSv and 0.036 mSv, in spiral tomography of complete edentulous mandible, computed tomography with standard mAs, computed tomography with low mAs and spiral tomography of a single tooth gap (p<0.05). Conclusions: Based on these results, it can be concluded that low mAs computed tomography is recommended instead of spiral tomography for the complete edentulous maxilla and mandible dental implant treatment planning.

  • PDF

A Cohort Study on Cancer Risk by Low-Dose Radiation Exposure among Radiation Workers of Nuclear Power Plants in Korea (저준위 방사선 노출의 암 유발에 관한 국내 원전종사자 코호트 연구)

  • Lim, Young-Khi;Yoo, Keun-Young
    • Journal of Radiation Protection and Research
    • /
    • v.31 no.2
    • /
    • pp.53-63
    • /
    • 2006
  • The increased risk of cancer with exposure to low-dose radiation was estimated through longitudinal study for radiation workers at the nuclear power plants in Korea. The radiation dose data were collected from the Radiation Safety Management System(RSMS) of the Korea Hydro & Nuclear Power Co., Ltd(KHNP). The cancer risks with radiation exposure were evaluated in terms of relative mortality ratios(RMR) and relative incidence ratios(RIR) to the unexposed employees at the nuclear power plants, and of the standardized mortality ratios(SMR) and standardized incidence ratios(SIR). There were no significant increases of canters of all sites in the exposed group either in RIR[1.08, 95% confidence interval(CI) 0.74-1.58] or in RMR[1.21, CI 0.70-2.08]. Neither SIR[0.81, CI 0.28-0.96] nor SMR[0.86, CI 0.66-1.10] significantly deviated from 1.0 for cancers of all sites. The trend analysis did not identify evident dose-response relationship due to insufficient numbers of the cases. Consequently, it is concluded that increases in cancer risks in the radiation worker group exposed to low doses at the nuclear power plants in Korea are not identified at this time.

The Effects of MDCK Cell on Low Dose Irradiation (저선량 방사선 조사가 배양 세포에 미치는 효과)

  • Lee, Song-Jae;Chang, Jae-Chul
    • The Journal of Korean Society for Radiation Therapy
    • /
    • v.9 no.1
    • /
    • pp.106-112
    • /
    • 1997
  • The present study was undertaken to investigate the effects of cultured MDCK cell line on the cell viability and the activities of superoxide dismutase(SOD). catalase, change of FOX 1 with low dose radiation. When MDCK cells were irradiated low dose (less than 50 cGy), the cell viability remains high after 2 hrs, but few changes after 24 hrs. In the low dose irradiated MDCK cells, the activities of SOD and catalase were increased with compared to control group and high dose. But the content of $H_2O_2$(FOX 1) was decreased. These results suggest that the cultured MDCK cells probably were induced expression of defense mechanism.

  • PDF

The Study of Energy Compensation Filter Thickness for Each Energy Area of Low Energy X-ray Beam Optimization on Active Electronic Personal Dosimeter (능동형 전자식 개인피폭선량계의 저에너지 X선 영역별 최적화를 위한 에너지보상 필터 두께에 대한 연구)

  • Kim, Jung-Su;Park, Youn-Hyun;Chae, Hyun-Sic
    • Journal of the Korean Society of Radiology
    • /
    • v.16 no.5
    • /
    • pp.519-526
    • /
    • 2022
  • Electronic personal dosimeter (EPD) provide real time monitoring and a direct indication of the accumulated dose or dose rate in terms of personal dose. Most EPD do not perform well in low energy photon radiation fields present in medical radiation environments. It has poor responsibility and large error rate for low energy photon radiation of medical radiation environments. This study evaluated to optimal additional filtration for EPD using silicon PIN photodiode detector form 40 to 120 kVp range in medical radiation environments. From 40 to 80 kVp energy range, Al 0.2 mm and Sn 1.0 mm overlapped filtration showed good responsibility to dose rate and from 80 kVp to 120 kVp energy range, Al 0.2 mm and Sn 1.6 mm overlapped filtration showed good responsibility to dose rate.

Efficacy and Safety of α-Lipoic Acid and Low Dose Pregabalin Combination in Painful Diabetic Neuropathy (당뇨병성 신경병증성 통증의 조절에 대한 α-Lipoic Acid와 저용량 Pregabalin 병용의 효능 및 안정성)

  • Ki-Tae, Park;Jin-Kwang, Lee;Se Jin, Park
    • Journal of Korean Foot and Ankle Society
    • /
    • v.26 no.4
    • /
    • pp.177-182
    • /
    • 2022
  • Purpose: The efficacy and safety of low-dose pregabalin and alpha lipoic acid in diabetic neuropathy were evaluated and analyzed. Materials and Methods: This study designed a retrospective study that included patients with diabetic neuropathic pain. From 2009 to 2022, 100 patients who suffered from diabetic neuropathic pain were included in this study. The patients were divided into group I (pregabalin 150 mg/day with alpha lipoic acid 600 mg/day) and group II (pregabalin 300 mg/day with alpha lipoic acid 600 mg/day). The visual analogue scale (VAS), medication side effects, and neurometer results were compared. Results: The mean follow-up period of the above patients was 120.23 weeks in group I and 149.05 weeks in group II. The average VAS score in group I decreased by 3.23 points, and the average VAS score in group II decreased by 2.86 points. Approximately 24.3% of group I had side effects, such as dizziness, sleepiness, and gastrointestinal trouble, while 76.7% of patients in group II had side effects. Sixtyseven patients had a neurometer examination before and after the medication, and there is no statistical difference between the two groups. Conclusion: The combination of low-dose pregabalin (pregabalin 150 mg/day) and alpha lipoic acid in diabetic neuropathy had a similar clinical effect and less frequent medication side effects than regular dose pregabalin (pregabalin 300 mg/day) and alpha lipoic acid. Therefore, low-dose pregabalin (pregabalin 150 mg/day) and alpha lipoic acid should be considered in treating diabetic neuropathy.

The Influences of Different Doses of Fish Oil on Serum Lipids in Patients with Non-Insulin Dependent Diabetes Mellitus (인슐린 비의존형 당뇨병 환자에서 어유 투여량이 혈청 지질에 미치는 영향)

  • 백인경
    • Journal of Nutrition and Health
    • /
    • v.26 no.6
    • /
    • pp.672-679
    • /
    • 1993
  • This study was designed to determine changes of serum glucose and lipid levels in noninsulin dependent diabetes mellitus patients during different doses of docosahexaenoic acid (DHA)-rich fish oil supplementation. All patients had a fasting blood glucose of less than 180mg/dl, a LDL-cholesterol of less than 160mg/dl, and a triglyceride of more than 160mg/dl. None had clinical evidence of renal, hepatic or coronary vascular disease. Sixteen patients served as control. Seven patients ingested 2.00g of fish oil(low dose group), consisting of 0.30g eicosapentaenoic acid(EPA) and 0.55g DHA. The group of modest dose(n=9) was provided 3.91g of fish oil, consisting 0.59g EPA and 1.08g DHA. After 4 weeks, serum triglyceride concentration showed a mild but nonsignificant elevation in control group, a 9% decrease(194 to 177mg/dl) in the group of low dose of fish oil and a 28% decrease(206 to 161mg/dl) in the group of modest dose. The level of high density lipoprotein(HDL), HDL2, HDL3 and total cholesterol in all groups were not changed. There was a mild increase in malondialdehyde and low density lipoprotein(LDL)-cholesterol concentration and decrease in $\alpha$-tocopherol concentration. However, these changes were not significant.

  • PDF

Gaussian process approach for dose mapping in radiation fields

  • Khuwaileh, Bassam A.;Metwally, Walid A.
    • Nuclear Engineering and Technology
    • /
    • v.52 no.8
    • /
    • pp.1807-1816
    • /
    • 2020
  • In this work, a Gaussian Process (Kriging) approach is proposed to provide efficient dose mapping for complex radiation fields using limited number of responses. Given a few response measurements (or simulation data points), the proposed approach can help the analyst in completing a map of the radiation dose field with a 95% confidence interval, efficiently. Two case studies are used to validate the proposed approach. The First case study is based on experimental dose measurements to build the dose map in a radiation field induced by a D-D neutron generator. The second, is a simulation case study where the proposed approach is used to mimic Monte Carlo dose predictions in the radiation field using a limited number of MCNP simulations. Given the low computational cost of constructing Gaussian Process (GP) models, results indicate that the GP model can reasonably map the dose in the radiation field given a limited number of data measurements. Both case studies are performed on the nuclear engineering radiation laboratories at the University of Sharjah.

INSTORE : A PC-Based Database Program for Occupational Radiation Exposure of a Nuclear Power Plant

  • Cho, Yeong-Ho;Kang, Chang-Sun;Mun, Ju-Hyung;Kim, Hak-Su
    • Nuclear Engineering and Technology
    • /
    • v.30 no.4
    • /
    • pp.308-317
    • /
    • 1998
  • Ensuring occupational radiation exposure(ORE) as low as is reasonably achievable(ALARA) has been one of very important requirements in a nuclear power plant. It is well known that about 70 percent of occupational dose has incurred from maintenance jobs in the outage period. To reduce occupational dose effectively, the high-dose jobs in the outage period should be identified with their dose reduction potentials and methods. In this study, a PC-based ORE database program, INSTORE, is developed to evaluate ORE doses in individual jobs, and the ORE data of Kori Units 3 and 4 are assembled to the database. Based on customary job classification, radiation work is classified into 26 main jobs which comprise 61 detailed jobs, and occupational doses are assessed according to each detailed job. As a result, high-dose jobs are identified with dose reduction priority in terms of collective ORE dose. It is recommended that adeqaute dose reduction methods for these jobs should be prepared to improve their working conditions and procedures.

  • PDF