• 제목/요약/키워드: low oxygen treatment

검색결과 417건 처리시간 0.03초

개선된 노우드 수술 후 신생아에서 발생한 종격동염의 Vacuum Assisted Closure를 이용한 치료 (Successful Application of Vacuum Assisted Closure in the Case of Neonatal Mediastinitis after Modified Norwood Operation)

  • 김도훈;양지혁;최진호;전태국
    • Journal of Chest Surgery
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    • 제39권9호
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    • pp.699-701
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    • 2006
  • 복잡 심기형 수술 후 종격동염과 흉골 감염은 비교적 흔하게 발생한다. 대부분의 환자군이 신생아 또는 영아이고, 조직 내의 저산소증이 동반되어 있으므로 상처치유가 늦고 침습적인 치료방법을 적용하기도 어렵다. 본 증례에서는 개선된 노우드 수술(modified Norwood operation) 이후 발생한 종격동염에 대하여 vacuum assisted closure를 이용하여 성공적으로 치료하였기에 1예를 보고하는 바이다.

Powder Preparation by Hydroxide Coprecipitation and Phase Development of Pb0.97La0.02(Zr0.64Sn0.25Ti0.11)O3 Ceramics

  • Lee, Joon-Hyung;Chiang, Yet-Ming
    • The Korean Journal of Ceramics
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    • 제4권3호
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    • pp.260-267
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    • 1998
  • A homogeneous and stoichimetric fine powder of the ferroelectric $Pb_[0.97}La_{0.02}(Zr_{0.64}Sn_{0.25}Ti_{0.11})O_3$ (PLZST) has been prepared by the hydroxide coprecipitation method. Studies on the crystallization behavior of precursor as a function of temperature by X-ray powder diffraction and transmission electron microscopy technique were consistent with the formation of the pyrochlore phase from amorphous, initially at low temperatures around 500~$550^{\circ}C$. Further heat treatment up to $750^{\circ}C$ resulted in development of the perovskite phase with no significant pyrochlore crystallite growth. At intermediate temperatures the precursor yields a fine mixture of pyrochlore and perovskite phases. When the pyrochlore phase was heat teated in air, slight weight increase was observed in the temperature range of 300~$700^{\circ}C$, which is thought to be caused from oxygen absorption. In argon atmosphere, weight increase was not observed. On the other hand, weight loss began to occur near $700^{\circ}C$, with giving off mostly CO2 gas. This implies that the pyrochlore phase seems to be crystallorgraphycally and thermodynamically metastable. An apparent activation energy of 53.9 ㎉/mol was estimated for the pyrochlore-perovskite phase transformation.

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누수 최소화를 위한 립 타입 전자력 플랩 밸브 (Lip Type Electromagnetic Flap Valve for Low Leakage)

  • 임인호;이기정;심우영;양상식
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2008년도 제39회 하계학술대회
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    • pp.1476-1477
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    • 2008
  • This paper reports on a flexible flap valve actuated by electromagnetic force under a constant pressure source. The flexible flap valve consists of the three main components: a flexible flap with a steel disk embedded in PDMS, an electromagnetic actuator and two glass plates with inlet and outlet. Sealing lip structures for improving the valve characteristics are added on the outlet of the bottom glass substrate. The flap valve is fabricated by the spin-coating process, the EDM process, SU-8 mold process and oxygen plasma treatment. The dimension of an assembled flap valve is $12mm{\times}20mm{\times}28mm$. The stroke volume of the flap valve is measured for various pressures and open times. When the input voltage of 30 V is applied for 0.33 s, the minimum stroke volume of the flap valve is 70 ${\mu}L$ at 50 kPa.

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Effects of chlorogenic acid on intracellular calcium regulation in lysophosphatidylcholine-treated endothelial cells

  • Jung, Hye-Jin;Im, Seung-Soon;Song, Dae-Kyu;Bae, Jae-Hoon
    • BMB Reports
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    • 제50권6호
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    • pp.323-328
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    • 2017
  • Lysophosphatidylcholine (LPC) is a major phospholipid component of oxidized low-density lipoprotein (ox-LDL) and is implicated in its atherogenic activity. This study investigated the effects of LPC on cell viability, intracellular calcium homeostasis, and the protective mechanisms of chlorogenic acid (CGA) in human umbilical vein endothelial cells (HUVECs). LPC increased intracellular calcium ($[Ca^{2+}]_i$) by releasing $Ca^{2+}$ from intracellular stores and via $Ca^{2+}$ influx through store-operated channels (SOCs). LPC also increased the generation of reactive oxygen species (ROS) and decreased cell viability. The mRNA expression of Transient receptor potential canonical (TRPC) channel 1 was increased significantly by LPC treatment and suppressed by CGA. CGA inhibited LPC-induced $Ca^{2+}$ influx and ROS generation, and restored cell viability. These results suggested that CGA inhibits SOC-mediated $Ca^{2+}$ influx and ROS generation by attenuating TRPC1 expression in LPC-treated HUVECs. Therefore, CGA might protect endothelial cells against LPC injury, thereby inhibiting atherosclerosis.

Au/$Ta_2$$O_5$/Pt MIM Capacitor의 annealing과 유전 특성 (A Study on the Dielectric and Annealing Properties in Au/$Ta_2$$O_5$/Pt MIM Capacitor)

  • 김인성;정순종;송재성;윤문수;박정후
    • 한국전기전자재료학회논문지
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    • 제14권12호
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    • pp.1016-1022
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    • 2001
  • This study presents the microstructure-electrical property relationship of reactive-sputtered Ta$_2$O$_{5}$ MIM capacitor structure processed by annealing in a vacuum and $O_2$ ambience. A microstructural investigation showed the existence of amorphous phase in as-deposited condition and the formation of preferentially oriented-Ta$_2$O$_{5}$ in $700^{\circ}C$ annealing. On annealing under the $O_2$ atmosphere, the Ta$_2$O$_{5}$ film exhibited the trend of its composition\`s approaching to stoichiometry from off-stoichiometry, analyzed by EPMA, the leakage current decrease and the enhanced temperature-capacitance characteristic stability. In the case of low temperature vacuum-annealing treatment, the leakage current behavior was stable irrespective of applied electric field. In the high temperature-annealed film at a vacuum condition, the electrical properties was observed to deteriorate. The results state that in Ta$_2$O$_{5}$ film annealed at $O_2$ atmosphere, gives rise to improvement of electrical characteristics in the capacitor were improved by reducing oxygen-vacancy and dandling Ta-O bond.-O bond.

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Effects of CoCl2 on multi-lineage differentiation of C3H/10T1/2 mesenchymal stem cells

  • Yoo, Hong Il;Moon, Yeon Hee;Kim, Min Seok
    • The Korean Journal of Physiology and Pharmacology
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    • 제20권1호
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    • pp.53-62
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    • 2016
  • Mesenchymal stem cells (MSCs) in the bone marrow and other somatic tissues reside in an environment with relative low oxygen tension. Cobalt chloride ($CoCl_2$) can mimic hypoxic conditions through transcriptional changes of some genes including hypoxia-inducible factor-$1{\alpha}$ (HIF-$1{\alpha}$) and vascular endothelial growth factor (VEGF). This study evaluated the potential role of $CoCl_2$ preconditioning on multi-lineage differentiation of C3H/10T1/2, a murine MSC line to understand its possible molecular mechanisms in vitro. $CoCl_2$ treatment of MSCs markedly increased HIF-$1{\alpha}$ and VEGF mRNA, and protein expression of HIF-$1{\alpha}$. Temporary preconditioning of MSCs with $CoCl_2$ induced up-regulation of osteogenic markers including alkaline phosphatase, osteocalcin, and type I collagen during osteogenic differentiation, followed by enhanced mineralization. $CoCl_2$ also increased chondrogenic markers including aggrecan, sox9, and type II collagen, and promoted chondrocyte differentiation. $CoCl_2$ suppressed the expression of adipogenic markers including $PPAR{\gamma}$, aP2, and $C/EBP{\alpha}$, and inhibited adipogenesis. Temporary preconditioning with $CoCl_2$ could affect the multi-lineage differentiation of MSCs.

Sur face Modification of Ultra High Molecular Weight Polyethylene Films by UV/ozone Ir radiation

  • Yun, Deuk-Won;Jang, Jin-Ho
    • 한국염색가공학회지
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    • 제23권2호
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    • pp.76-82
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    • 2011
  • Ultra High molecular weight polyethylene(UHMWPE) films were photooxidized by UV/ozone irradiation. Reflectance of the irradiated films decreased in the low wavelength regions of visible light, indicating destructive interference of visible light due to roughened surface. The UV treatment developed the nano-scale roughness on the UHMWPE films surface, which increased by two-fold from 82.6 to 156.6nm in terms of peak-valley roughness. The UV irradiation caused the oxygen content of the UHMWPE film surface to increase. Water contact angle decreased from $83.2^{\circ}$ to $72.9^{\circ}$ and surface energy increased from 37.8 to 42.6mJ/$m^2$ with increasing UV energy. The surface energy change was attributed to significant contribution of polar component rather than nonpolar component indicating surface photooxidation of UHMWPE films. The increased dyeability to cationic dyes may be due to the photochemically introduced anionic and dipolar dyeing sites on the film surfaces.

급속반응공정에 의한 동 테이프 $Bi_{2}Sr_{2}CaCu_{2}O_{8}$ (Fabrication of $Bi_{2}Sr_{2}CaCu_{2}O_{8}$ Superconducting Films by the LiReac-PreCu Method)

  • 성현태;한상철;한영희;이준성;최희락
    • 한국초전도ㆍ저온공학회논문지
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    • 제1권1호
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    • pp.7-14
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    • 1999
  • Wekk oriented $Bi_{2} Sr_{2} CaCu_{2} O_{8}$ suppercondcting thick films were fabricared on copper tape by LiReac-PreCu (liquid reaction between a Cu-free precousor and Cu tape) method. Cu-free precursor power which is composed of $Bi_{2}Sr_{2}Ca_{5}$ was printed on a copper tape by screen printing and was heat-treated. The speciment were partially in a molten state at the heat treatment temperature (85$0^{\circ}C$~87$0^{\circ}C$). The heat heat treatments for the reaction were performed in air or low oxygen pressure in several stages. XRD analyses of the resulting Bi2Sr2CaCu2O8 superconducting tapes show that the $Bi_{2} Sr_{2} CaCu_{2} O_{8}$ phase is dominant and a small amount of $Bi_{2} Sr_{2} Cu_{2} O_{6}$ phase is detected. Both phases are aligned in the c-axis direction.

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Effect of myoglobin, hemin, and ferric iron on quality of chicken breast meat

  • Zhang, Muhan;Yan, Weili;Wang, Daoying;Xu, Weimin
    • Animal Bioscience
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    • 제34권8호
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    • pp.1382-1391
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    • 2021
  • Objective: The objective was to evaluate the impact of different forms of iron including myoglobin, hemin, and ferric chloride on the quality of chicken breast meat. Methods: Chicken breast muscles were subjected to 1, 2, 3 mg/mL of FeCl3, myoglobin and hemin treatment respectively, and the production of reactive oxygen species (ROS) and malondialdehyde, meat color, tenderness, water holding capacity and morphology of meat was evaluated. Results: Hemin was found to produce more ROS and induce greater extent of lipid oxidation than myoglobin and ferric chloride. However, it showed that hemin could significantly increase the redness and decrease the lightness of the muscle. Hemin was also shown to be prominent in improving water holding capacity of meat, maintaining a relatively higher level of the immobilized water from low-field nuclear magnetic resonance measurements. Morphology observation by hematoxylin-eosin staining further confirmed the results that hemin preserved the integrity of the muscle. Conclusion: The results indicated that hemin may have economic benefit for the industry based on its advantage in improving water holding capacity and quality of meat.

Control of Galvanic Corrosion Between A516Gr.55 Steel and AA7075T6 Depending on NaCl Concentration and Solution Temperature

  • Hur, S.Y.;Jeon, J.M.;Kim, K.T.;Kim, Y.S.
    • Corrosion Science and Technology
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    • 제19권6호
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    • pp.281-287
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    • 2020
  • Chloride ion is one of the most important corrosive agents in atmospheric corrosion, especially in marine environments. It has high adsorption rate and increases the conductivity of electrolytes. Since chloride ions affect the protective properties and the surface composition of the corrosion product, they increase the corrosion rate. A low level of chloride ions leads to uniform corrosion, whereas a high level of chloride ions may induce localized corrosion. However, higher solution temperatures tend to increase the corrosion rate by enhancing the migration of oxygen in the solution. This work focused on the effect of NaCl concentration and temperature on galvanic corrosion between A516Gr.55 carbon steel and AA7075T6 aluminum alloys. When AA7075T6 aluminum alloy was galvanically coupled to A516Gr.55 carbon steel, AA7075T6 was severely corroded regardless of NaCl concentration and solution temperature, unlike the corrosion properties of single specimen. The combined effect of surface treatment involving carbon steel and aluminum alloy on corrosion behavior was also discussed.