• 제목/요약/키워드: low dose gamma radiation

검색결과 232건 처리시간 0.022초

Understanding Phytosanitary Irradiation Treatment of Pineapple Using Monte Carlo Simulation

  • Kim, Jongsoon;Kwon, Soon-Hong;Chung, Sung-Won;Kwon, Soon-Goo;Park, Jong-Min;Choi, Won-Sik
    • Journal of Biosystems Engineering
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    • 제38권2호
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    • pp.87-94
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    • 2013
  • Purpose: Pineapple is now the third most important tropical fruit in world production after banana and citrus. Phytosanitary irradiation is recognized as a promising alternative treatment to chemical fumigation. However, most of the phytosanitary irradiation studies have dealt with physiochemical properties and its efficacy. Accurate dose calculation is crucial for ensuring proper process control in phytosanitary irradiation. The objective of this study was to optimize phytosanitary irradiation treatment of pineapple in various radiation sources using Monte Carlo simulation. Methods: 3-D geometry and component densities of the pineapple, extracted from CT scan data, were entered into a radiation transport Monte Carlo code (MCNP5) to obtain simulated dose distribution. Radiation energy used for simulation were 2 MeV (low-energy) and 10 MeV (high-energy) for electron beams, 1.25 MeV for gamma-rays, and 5 MeV for X-rays. Results: For low-energy electron beam simulation, electrons penetrated up to 0.75 cm from the pineapple skin, which is good for controlling insect eggs laid just below the fruit surface. For high-energy electron beam simulation, electrons penetrated up to 4.5 cm and the irradiation area occupied 60.2% of the whole area at single-side irradiation and 90.6% at double-side irradiation. For a single-side only gamma- and X-ray source simulation, the entire pineapple was irradiated and dose uniformity ratios (Dmax/Dmin) were 2.23 and 2.19, respectively. Even though both sources had all greater penetrating capability, the X-ray treatment is safer and the gamma-ray treatment is more widely used due to their availability. Conclusions: These results are invaluable for optimizing phytosanitary irradiation treatment planning of pineapple.

Radiation testing of low cost, commercial off the shelf microcontroller board

  • Fried, Tomas;Di Buono, Antonio;Cheneler, David;Cockbain, Neil;Dodds, Jonathan M.;Green, Peter R.;Lennox, Barry;Taylor, C. James;Monk, Stephen D.
    • Nuclear Engineering and Technology
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    • 제53권10호
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    • pp.3335-3343
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    • 2021
  • The impact of gamma radiation on a commercial off the shelf microcontroller board has been investigated. Three different tests have been performed to ascertain the radiation tolerance of the device from a nuclear decommissioning deployment perspective. The first test analyses the effect of radiation on the output voltage of the on-board voltage regulator during irradiation. The second test evaluated the effect of gamma radiation on the voltage characteristics of analogue and digital inputs and outputs. The final test analyses the functionality of the microcontroller when using an external, shielded voltage regulator instead of the on-board voltage regulator. The results suggest that a series of latch-ups occurs in the microcontroller during irradiation, causing increased current drain which can damage the voltage regulator if it does not have short-circuit protection. The analogue to digital conversion functionality appears to be more sensitive to gamma radiation than digital and analogue output functionality. Using an external, shielded voltage regulator can prove beneficial when used for certain applications. The collected data suggests that detaching the voltage regulator can extend the lifespan of the platform up to approximately 350 Gy.

저선량의 감마선 피폭된 사람 말초 임파구의 미소핵을 이용한 방사선 생물학적 피폭선량 측정법 연구 (Cytokinesis-blocked micronuclei in the human peripheral lymphocytes following low dose γ-rays irradiation)

  • 김태환
    • 대한수의학회지
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    • 제41권1호
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    • pp.99-104
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    • 2001
  • 불의의 방사선 피폭 환자의 체내 방사선 피폭선량의 예측을 위한 방사선 생물학적 선량측정 개발의 일환으로 저선량 피폭환자의 체내 피폭선량 측정 지표로서의 미소핵 분석법 이용 가능성을 평가하기 위하여 코발트-60 감마선을 0.25 Gy에서 1 G의 선량을 인체 말초 혈액에 조사한 후 임파구내에 미소핵의 수적 변화를 형태학적으로 관찰하였다. 저선량에 피폭된 임파구에서 미소핵이 관찰되었으며, 선량에 따른 수적인 변화도 나타났다. 저선량 피폭에 대한 미소핵의 수적 변화에 대한 선량-반응 곡선은 $Y=(0.02{\pm}0.0009)+(0.033{\pm}0.010)D+(0.012{\pm}0.012)D^2$의 식을 얻었으며, linear quadratic model 이였다. 이상의 결과에서 미소핵의 발생 빈도와 피폭 선량간에 유의한 효과가 있는 것으로 확인되었다. 그리고 정상대조군에서는 세포당 $0.02{\pm}0.0009$개가 관찰되었다. 따라서 말초 임파구를 이용한 미소핵 분석법은 저선량 피폭환자의 체내 피폭선량 측정은 물론 방사선 방호제의 검색 및 방사선 민감도 검사를 위한 방사선 생물학적 지표로 이용 가능하며, 특히 이 방법은 간편하고 정확하며 재현성이 있는 방법으로 불의의 방사선 피폭 사고시 체내 피폭선량을 예측하는 좋은 지표로 사용되어질 수 있을 것으로 사료됨.

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PREVENTION OF CIGARETTE SMOKE INDUCED LUNG CANCER BY LOW LET IONIZING RADIATION

  • Sanders, Charles L.
    • Nuclear Engineering and Technology
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    • 제40권7호
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    • pp.539-550
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    • 2008
  • Lung cancer is the most prevalent global cancer, ${\sim}90%$ of which is caused by cigarette smoking. The LNT hypothesis has been inappropriately applied to estimate lung cancer risk due to ionizing radiation. A threshold of ${\sim}1\;Gy$ for lung cancer has been observed in never smokers. Lung cancer risk among nuclear workers, radiologists and diagnostically exposed patients was typically reduced by ${\sim}40%$ following exposure to <100 mSv low LET radiation. The consistency and magnitude of reduced lung cancer in nuclear workers and occurrence of reduced lung cancer in exposed non-worker populations could not be explained by the HWE. Ecologic studies of indoor radon showed highly significant reductions in lung cancer risk. A similar reduction in lung cancer was seen in a recent well designed case-control study of indoor radon, indicating that exposure to radon at the EPA action level is associated with a decrease of ${\sim}60%$ in lung cancer. A cumulative whole-body dose of ${\sim}1\;Gy$ gamma rays is associated with a marked decrease in smoking-induced lung cancer in plutonium workers. Low dose, low LET radiation appears to increase apoptosis mediated removal of $\alpha$-particle and cigarette smoke transformed pulmonary cells before they can develop into lung cancer.

한국의 환경방사선준위(環境放射線準位)($1961{\sim}1980$) (Environmental Radiation Level in Korea($1961{\sim}1980$))

  • 노재식
    • Journal of Radiation Protection and Research
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    • 제6권1호
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    • pp.1-7
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    • 1981
  • This report presents the results of the environmental radiation program at Korea Advanced Energy Research Institute (KAERI) ($37^{\circ}38'N,\;127^{\circ}05'E$) and its surroundings for the last two decades (January, 1961 through December, 1980). In the 1960s, the monthly mean levels of environmental external radiation encountered ranged from a low of 14.2 microroentgen per hour to a high of 42.2 microroentgen per hour with a mean of 21.7 microroentgen per hour, while in 1970s it ranged from a low of 12.4 microroentgen per hour to a high of 40.8 microroentgen per hour with a mean of 20.4 microroentgen per hour. It may, therefore, be said that environmental radiation dose rates remained almost unchanged for the two decades except for the second half of 1960s and the first half of 1970s during which the off-site and on-site patterns were frequently unlike in form and intensity with appreciable differences between average values. Particular results of interest with respect to the effects of the fallout gamma dose rate on environmental radiation show that elevated levels were encountered in association with the deposits of fresh debris from Chinese and Russian nuclear weapons tests in particular.

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식도암 세기조절방사선치료와 용적세기조절회전치료에 대한 Jaw-Tracking의 유용성 평가 (Effectiveness Assessment on Jaw-Tracking in Intensity Modulated Radiation Therapy and Volumetric Modulated Arc Therapy for Esophageal Cancer)

  • 오현택;유순미;전수동;김민수;송흥권;윤인하;백금문
    • 대한방사선치료학회지
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    • 제31권1호
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    • pp.33-41
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    • 2019
  • 목 적: 식도암 방사선치료 시 세기조절방사선치료(Intensity Modulated Radiation Therapy, IMRT) 및 용적세기조절회전치료(Volumetric Modulated Arc Therapy, VMAT)에서 Jaw-Tracking 기법 유 무에 따라 저선량 영역에 대한 주변 정상장기의 용적선량을 분석하여 그 유용성을 평가하고자 한다. 대상 및 방법: 본 원에서 사용하고 있는 선형가속기 VitalBeamTM(Varian Medical System, U.S.A)으로 식도암 방사선치료를 받은 27명을 대상으로 하였으며, 치료계획은 Eclipse(Ver. 13.6 Varian, U.S.A)를 이용하여 Jaw-Tracking(JT)을 사용한 치료계획과 Non Jaw-Tracking(NJT) 치료계획을 수립하였으며, 치료계획용적(Planning Target Volume, PTV)에 빗장위림프절(Supraclavicular Lymph Nodes, SCL)이 포함되어 있는 T자형 PTV를 가진 환자를 대상으로 하였다. 조사범위에 대한 영향을 확인하기 위해 복강(Celiac) 포함 여부로 비교군을 나누었다. 수립된 치료계획의 비교를 위해 손상위험장기는 양측 폐, 심장, 척수를 비교하였으며 Conformity Index(CI), Homogeneity Index(HI)를 비교하였다. 임상적용 검증을 위해 전자포탈영상장치(Electronic Portal Imaging Device, EPID)를 이용하여 Portal Dosimetry를 실시하였고, 선량 영역의 임계치(Threshold)를 10 %, 5 %, 0 %로 매개변수로 설정하여 감마분석을 실시하였다. 결 과: 모든 치료계획은 3 mm / 3 %, 감마통과율 95 % 기준에 대해 Threshold 10 %의 경우 95 % 이상으로 JT, NJT 모두 통과하였으며, IMRT는 Threshold가 5 %, 0 %로 줄어들수록 JT보다 NJT의 값이 1 % 이상 줄어 들었다. IMRT에서 양측 폐의 $V_5$$V_{10}$은 JT에서 Celiac을 포함하지 않을 때 최대 14.7 %, 평균 8.5 %, 5.3 % 만큼 감소했고, $D_{mean}$$72.3{\pm}51cGy$ 감소하였으며, Celiac을 포함할 때 JT에서 선량감소가 증가하였다. 심장의 $D_{mean}$$68.9{\pm}38.5cGy$, 척수의 $D_{max}$$39.7{\pm]30.1cGy$만큼 감소하였다. VMAT은 JT기법 사용 시 폐에서 $V_5$ 평균 2.5 % 감소하였고, 심장 및 척수에서 소량 감소하였으며, Celiac 포함 시 JT의 선량감소가 증가하였다. 결 론: 식도암 치료계획에서 IMRT가 JT 사용 시 양측 폐의 $V_5$, $V_{10}$에서 유의미한 감소가 나타났고, 저 선량영역에서 조사범위가 클수록 선량감소가 크게 나타났다. 따라서 식도암 방사선치료에는 IMRT가 VMAT보다 JT 적용 시 더 효과적이며, 저 선량영역에서의 MLC 누설 및 투과선량으로부터 정상장기를 보호할 수 있다.

ESR을 이용한 저밀도 폴리에틸렌의 방사선 열화에 관한 연구 (A study on radiation degradation of LDPE by using ESR)

  • 김기엽;김진아;이청;김평종;류부형
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 2004년도 하계학술대회 논문집 Vol.5 No.1
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    • pp.473-476
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    • 2004
  • This study has investigated radiation degradation of low density polyethylene(LDPE). Samples were irradiated using a $Co^{60}\;\gamma-ray$ and ray up to 800 kGy at a dose rate of 5 kGy/hr in the presence of air atmosphere at room temperature. After irradiation, free radical measurement of LDPE has established by electron spin resonance(ESR). Then, each sample was stored for 2 weeks. ESR measurement showed that free radical concentration(FRC) was increased with radiation dose and changed from alkyl, allyl radical to peroxy radical with time.

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Development of Radiopharmaceutical DW-166HC for Anticancer drug

  • Man, Ryu-Jei
    • 한국응용약물학회:학술대회논문집
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    • 한국응용약물학회 1999년도 춘계학술대회
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    • pp.53-61
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    • 1999
  • Radiation therapy has been used for the cancer treatment and radiation synovectomy$\^$1-3)/. There are two kinds of radiation therapy; the external radiation therapy and the internal radiation therapy. Hitherto, the external radiation therapy has been widely used, but for the lack of its selectivity it requires strong radiation dose and causes the irritation and damage of the normal tissue or organ. Therefore many researchers give their interests to the internal radiation therapy in which the radioactive materials are injected directly into the target organ or tissue. Many ${\beta}$-emitting radionuclides have been studied for the application of the internal radiation theraily. Among them, Holmium-166 has the many beneficial physical characteristics for the internal radiation therapy such as appropriate half life (26.8hr), high ${\beta}$ energy (max. 1.85 MeV(51%), 1.77 MeV (48%), mean 0.67MeV), and low ${\gamma}$ energy (0.081MeV) easily detected by ${\gamma}$-camera. In the internal radiation therapy, the administered radioactive materials should be retained in the target long enough to increase the therapeutic effects and avoid the damage in the normal tissue or organ. For this purpose, radionuclides are used as complex form with carriers. Carriers should have a high affinity with radionuclides in vivo and in vitro, so the complex can be evenly distributed in the lesion but can not be leaked out from the lesion.

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감마선 이용 저염 오징어젓갈 제조시 미생물적, 관능적 품질변화 (Effects of Gamma Irradiation on Microbiological and Sensory Qualities in Processing of Low Salted and Fermented Squid)

  • 김재훈;이경행;안현주;차보숙;변명우
    • 한국식품과학회지
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    • 제31권4호
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    • pp.1050-1056
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    • 1999
  • 식품첨가제의 사용없이도 저장성과 향미특성이 우수한 저염 오징어젓갈을 개발하기 위한 방법으로 감마선 조사기술을 이용하였다. 식염농도를 각각 5%, 10%, 20%로 조절한 오징어젓에 감마선을 조사한 후 $15^{\circ}C$$25^{\circ}C$에서 발효시키면서 일반성분, 식염함량, 수분활성도, pH, 총균수 및 관능적 품질 변화를 조사하였다. 감마선 조사직후 또는 발효기간 중 일반성분과 식염함량 및 수분활성은 감마선 조사에 의해 영향을 받지 않았다. 오징어젓갈의 총균수와 pH는 식염농도와 감마선 조사선량 및 발효온도에 따라 영향을 받았으며, 10%의 식염 첨가와 10 kGy의 감마선 조사를 병용처리한 오징어젓을 $15^{\circ}C$에서 발효시킨 경우 비조사구에 비해 적절한 미생물의 생육 저해로 저장기간 연장 효과를 보였고, 30일까지 관능적 품질이 적합하게 유지되는 것으로 나타났다.

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