• Journal of the Korean GEO-environmental Society
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• v.24 no.2
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• pp.25-30
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• 2023

The high-strength rockfall net developed in this study is to replace the fallout prevention net method using PVC coating net made of core wire thickness 3.2 mm and tensile strength 290-540 MPa class steel wire. General PVC coating net have low performance, and in the event of falling rocks or surface loss, they cannot withstand the load and are torn, which rather adds to the damage. Developed rockfall net was manufactured using steel wires with a core wire thickness of 2.8 to 3.2 mm and a tensile strength of 1,000 to 2,000 MPa. Test method was referred to the international standard Steel wire rope net panels and rolls-Definitions and specifications (ISO 17746:2016), and was conducted in accordance with the provisions of the punching test. Through indoor punching tests, the load-displacement curves of the general PVC coating network and the developed high-strength capture net (1,000 and 2,000 MPa) were compared, and the maximum Pull-out load was analyzed to be improved by 324.47% (2,000 MPa high-strength net).

• Journal of Dental Anesthesia and Pain Medicine
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• v.23 no.1
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• pp.9-17
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• 2023

Background: Dental evaluation and protection are important for preventing traumatic dental injuries when patients are under general anesthesia. The objective of the present study was to develop a questionnaire based on dentition-related risk factors that could serve as a valuable tool for dental evaluation and documentation. Methods: We developed a questionnaire for dental evaluation before administration of general anesthesia, investigated the association between patient-and-dentist responses and mouthguard fabrication, and assessed response agreement between 100 patients. Results: Protective mouthguards were fabricated for 27 patients who were identified as having a high risk of dental injury. There was a strong association between dentists' responses and mouthguard fabrication, depending on the general oral health status, use of ceramic prosthesis, presence of masticatory pain related to periodontal diseases, gingival edema, and implants (P < 0.05). Response agreement between patients and dentists for items related to dental pain, loss of dental pulp vitality, root canal therapy, dental trauma, aesthetic prosthesis, tooth mobility, and implant prosthesis was high (Cohen's kappa coefficient κ ≥ 0.6). Conclusions: A high agreement was observed between patient-dentist responses and a strong association with mouthguard fabrication for items pertaining to ceramic prosthesis, masticatory pain, and dental implants. Patients with a "yes" response to these items are recommended to undergo a dental evaluation and use a dental protective device while under general anesthesia.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.24 no.1
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• pp.73-77
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• 1979

An artificial lodging was made at various growth stages of the soybean varieties Clark and KAS 100-3-1 to evaluate its effect on seed yield and other important agronomic characters. Results showed general increases in plant height and number of branches per plant whereas reductions in seed weight. number of nodes, pods and seeds per plant in the severly lodged plots. As compared to prevention of lodging, about 40 percent yield reduction was caused by the severe lodging treatrment. Furthermore, the most severe lodging before blooming resulted in about 66% yield loss.

• Biomedical Science Letters
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• v.28 no.4
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• pp.237-246
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• 2022

Ischemia-reperfusion results in excess reactive oxygen species (ROS) that affect myocardial cell damage. ROS production inhibition is effectively proposed in treating cardiovascular diseases including myocardial hypertrophy. Studies have shown that oxidizing cultured cells in in vitro experiments gradually decreases the permeability of mitochondrial membranes time- and concentration-dependent, resulting in increased mitochondrial membrane damage due to secondary ROS production and cardiolipin loss. However, recent studies have shown that 5-iodo-6-amino-1,2-benzopyrone (INH₂BP), an anticancer and antiviral drug, inhibited peroxynitrite-induced cell damage in in vitro and alleviated partial or overall inflammation in animal experiments. Therefore, in this paper, we studied the preventive effect of INH₂BP on H9c2 cells derived from mouse heart damaged by oxidative stress using 700 μM of hydrogen peroxide. As a result of oxidative stress to H9c2 cells by hydrogen peroxide whether the treatment of INH₂BP or not, hydrogen peroxide caused serious damage in H9c2 cells. These results were confirmed with cell viability and Hoechst 33342 assays. And this damage was through cell death. However, it was confirmed that H9c2 cells pretreated with INH₂BP significantly reduced cell death by hydrogen peroxide. In addition, measurements with DCF-DA assay to determine whether ROS is produced in H9c2 cells treated with only hydrogen peroxide produced ROS significantly, but H9c2 cells pretreated with INH₂BP significantly reduced ROS production by hydrogen peroxide. Taken together, it is believed that INH₂BP can be useful for the prevention and treatment of cardiovascular diseases induced through oxidative stress such as heart damage caused by ischemia/reperfusion.

• Journal of dental hygiene science
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• v.23 no.4
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• pp.296-301
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• 2023

Background: Periodontal disease is a major cause of tooth loss in adults and is a representative oral disease commonly suffered by most people around the world. Mainly the proliferation of Gram-negative bacteria and secreted virulence factors cause an inflammatory response and destroy periodontal tissue. Gossypetin, isolated from Hibiscus sabdariffa L, is known to have various pharmacological effects, including antibacterial and anticancer activities. We aimed to confirm the anti-inflammatory effect of gossypetin through interleukin-6 (IL-6) regulation in human gingival fibroblasts (HGFs) stimulated with lipopolysaccharide (LPS) of Porphyromonas gingivalis, a major cause of adult periodontitis. Methods: CCK-8 assay was performed to confirm the concentration-dependent cytotoxicity of gossypetin against HGFs. The secretion level and mRNA expression of IL-6, an inflammation-related cytokine, and the effect of gossypetin on these in HGFs stimulated with P. gingivalis LPS were confirmed by ELISA and qRT-PCR analysis, respectively. Results: Up to a concentration of 100 µM gossypetin with or without P. gingivalis LPS, the survival rate for HGFs was maintained at over 95% and showed no toxicity. ELISA and qRT-PCR analysis results showed that P. gingivalis LPS increased IL-6 secretion and mRNA levels in HGFs compared to the control group. However, this increase in IL-6 was significantly down-regulated by gossypetin treatment in a dose-dependent manner. In particular, 80 µM gossypetin inhibited IL-6 production to the level of the control group. Conclusion: These results indicated that gossypetin attenuated IL-6 production in HGFs stimulated by P. gingivalis LPS, which may ultimately suppress the inflammatory response in periodontal tissue. Therefore, gossypetin may have potential as a natural ingredient for the prevention and treatment of periodontal disease.

• Korean Journal of Veterinary Service
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• v.46 no.4
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• pp.339-348
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• 2023

The outbreak of lumpy skin disease (LSD), caused by LSD virus (LSDV), in Jeollabuk-do was first confirmed at a Korean cattle farm in Buan-gun on October 24, 2023. Afterwards, thirteen cases (twelve cases in Gochang-gun and a case in Imsil-gun) were further confirmed, resulting in a total of fourteen cases over 25 days until November 17, 2023. Clinical examination were conducted on infected and co-habitting cattle from the LSD-affected farms with particular focus on the presence of nodules throughout the body such as head, neck, chest, femur, head, and perineum. As a results, abnormal clinical signs were observed in fifteen cows: loss of appetite in six cows, high fever in three cows, eye mucosal nodules in a cow, nasal mucosal nodules in six cows, nodules on perineum in five cows, scrotum nodules in two cows, papillary nodules in a cow, and/or skin nodules in eleven cows. By the PCR methods, the common gene of capripox virus and/or the specific gene of LSDV were detected in 35 of the 69 cows tested this study. In the Farm1, capripox virus-specific gene, LSDV wild strain-specific gene, and LSDV vaccine strain-spcific gene were simultaneously detected in affected cows, indicating the cattle farm was affected by various strain of LSDV. As a result of combining clincal examination and PCR test, it was found that clinically and subclinically infeted cows coexist in the LSDV-infected farms. These finding in this study will be a great help in diagnosis and prevention of the LSD in Korean cattle farms.

• Convergence Security Journal
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• v.23 no.5
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• pp.181-187
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• 2023

Recently, military operations have been aimed at winning using various information, analysis, weapons, and operation systems. These systems should consist of integrated composition and the function of analyzing and sharing data. Accordingly, military C4I collects and analyzes a lot of data and produces and shares secrets to perform effective operations. However, C4I cannot operate in electronic form from secret production to disposal. And as it is managed based on the output, problems such as difficulty in management and loss/leakage arise. Therefore, in this paper, we propose an ESDMB(Electronic Secret Document Management whit Bloockchain) plan based on blockchain technology to manage all secrets in electronic document format and provide integrity and denial prevention. In particular, the blockchain-based proposal method will be suitable as a protection measure against manipulation and leakage, from secret production to destruction.

• International Journal of Internet, Broadcasting and Communication
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• v.16 no.2
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• pp.237-246
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• 2024

In recent years, the frequent occurrence of fire accidents in university libraries has posed significant threats to the safety of students' lives and property, alongside negative social impacts. Accurately analyzing the factors affecting evacuation during library fires and proposing optimized measures for safe evacuation is thus crucial. This paper utilizes a specific university library as a case study, simulating fire evacuation scenarios using the Pathfinder software, to assess and validate evacuation strategies and propose relevant optimizations. Pathfinder, developed by Thunderhead Engineering in the United States, is an intuitive and straightforward personnel emergency evacuation assessment system, offering advanced visualization interfaces and 3D animation effects. This study aims to construct evacuation models and perform simulation analysis for the selected university library using Pathfinder. The library's structural layout, people flow characteristics, and the nature of fire and smoke spread are considered in the analysis. Additionally, evacuation scenarios involving different fire outbreak locations and the status of emergency exits are examined. The findings underscore the importance of effective evacuation in fire situations, highlighting how environmental conditions, individual characteristics, and behavioral patterns significantly influence evacuation efficiency. Through these investigations, the study enhances understanding and optimization of evacuation strategies in fire scenarios, thereby improving safety and efficiency. The research not only provides concrete and practical guidelines for building design, management, and emergency response planning in libraries but also offers valuable insights for the design and management of effective evacuation systems in buildings, crucial for ensuring occupant safety and minimizing loss of life in potential hazard situations

• International Journal of Internet, Broadcasting and Communication
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• v.16 no.2
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• pp.209-217
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• 2024

Recent years have seen a notable increase in fire incidents in university cafeterias, yet the social attention to these occurrences remains limited. Despite quick responses to these incidents preventing loss of life, the need for large-scale evacuation in such high foot traffic areas can cause significant disruptions, economic losses, and panic among students. The potential for stampedes and unpredictable damage during inadequate evacuations underscores the importance of fire safety and evacuation research in these settings. Previous studies have explored evacuation models in various university environments, emphasizing the influence of environmental conditions, personal characteristics, and behavioral patterns on evacuation efficiency. However, research specifically focusing on university cafeterias is scarce. This paper addresses this gap by employing Pathfinder software to analyze fire spread and evacuation safety in a university cafeteria. Pathfinder, an advanced emergency evacuation assessment system, offers realistic 3D simulations, crucial for intuitive and scientific evacuation analysis. The studied cafeteria, encompassing three floors and various functional areas, often exceeds a capacity of 1500 people, primarily students, during peak times. The study includes constructing a model of the cafeteria in Pathfinder and analyzing evacuation scenarios under different fire outbreak conditions on each floor. The paper sets standard safe evacuation criteria (ASET > RSET) and formulates three distinct evacuation scenarios, considering different fire outbreak locations and initial evacuation times on each floor. The simulation results reveal the impact of the fire's location and the evacuation preparation time on the overall evacuation process, highlighting that fires on higher floors or longer evacuation preparation times tend to reduce overall evacuation time.In conclusion, the study emphasizes a multifaceted approach to improve evacuation safety and efficiency in educational settings. Recommendations include expanding staircase widths, optimizing evacuation routes, conducting regular drills, strengthening command during evacuations, and upgrading emergency facilities. The use of information and communication technology for managing emergencies is also suggested. These measures collectively form a comprehensive framework for ensuring safety in educational institutions during fire emergencies.

• Journal of dental hygiene science
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• v.24 no.2
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• pp.97-106
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• 2024

Background: Periodontitis and peri-implantitis are diseases caused by pathogenic microorganisms that cause tissue damage and alveolar bone destruction resulting in the loss of teeth and implants. Due to the biological differences in the tissues surrounding the implants, peri-implantitis progresses more rapidly and intensely than periodontitis, underscoring the importance of understanding the characteristics and interactions of pathogenic bacteria. This study aimed to quantitatively analyze the pathogenic microorganisms associated with periodontitis and peri-implantitis in Korean patients and evaluate the correlation between these bacteria. Methods: A total of 98 (52 males and 46 females) were randomly selected and classified into three groups (healthy group [HG]=25; periodontitis group [PG]=31; and peri-implantitis group [PIG]=42). The relative expression levels of 11 pathogenic microorganisms collected from the gingival sulcus fluid were determined using multiplex real-time polymerase chain reaction. Results: Eikenella corrodens, Fusobacterium nucleatum, and Prevotella nigrescens were highly prevalent in the HG, PG, and PIG patients. The results of the relative quantitative analysis of microorganisms showed that all bacteria belonging to the green, orange, and red complexes were significantly more abundant in the PG and PIG than in the HG (p<0.05). Porphyromonas gingivalis in the red complex showed a positive correlation with all microorganisms in the orange complex (p<0.05). Campylobacter rectus in the orange complex showed a significant positive correlation with all microorganisms in the red complex, and with F. nucleatum, P. nigrescens, Prevotella intermedia, and Eubacterium nodatum (p<0.05). Conclusion: P. gingivalis, C. rectus, and F. nucleatum exhibit strong interactions. Removing these bacteria can block complex formation and enhance the prevention and treatment of periodontitis and peri-implantitis.