• Journal of Acupuncture Research
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• 제34권3호
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• pp.49-58
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• 2017

Objectives : The purpose of this study is to provide data to guide dementia health-care policy in Korea and to establish the position of Korean medical specialists in long-term care hospitals by analyzing the data of dementia inpatients. We analyzed the actual condition of dementia patients in care hospital and the effect of Western-Korean cooperative medicine on the progress of dementia. Methods : From January 1, 2016 to December 31, 2016, inpatients who were diagnosed with dementia at Mungyeong municipal long-term care hospital and admitted for more than 3 months were enrolled. Their medical records and simple tests were analyzed retrospectively. Results : We examined the detailed diagnosis, including both main and sub diagnosis, and Alzheimer disease dementia, at 97%, was the most common. At the time of admission, Korean Version of the Mini-Mental State Exam (K-MMSE) analysis showed that severe dementia affected 52%, and most were rated as Geriatric Depression Scale (GDS) 6. Based on the admission date, the results of a simplified test applied to the dementia patients every 6 months showed an maintain in the K-MMSE and GDS scores in 83%. Conclusion : The results of this study show that the rate of progression of dementia is somewhat lower in inpatients with moderate to severe Alzheimer's who have received Western-Korean cooperative treatment. However, due to institutional limitations, long-term inpatients such as those with dementia do not receive active traditional Korean medical treatment; hence, it is necessary to improve the national institution of traditional Korean medicine in long-term care hospitals.

• Journal of Korean Neurosurgical Society
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• 제43권4호
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• pp.182-185
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• 2008

Objective : The purpose of the present study is to assess the long-term results of microsurgical dorsal root entry zonotomy (MDT) for the treatment of medically intractable upper-extremity spasticity. Methods : The records of nine adult patients who underwent MDT by one operating neurosurgeon from March 1999 to June 2004 were retrospectively reviewed by another investigator who had no role in the management of these patients. In all patients, MDT was performed on all roots of the upper limb (from C5 to T1) for spasticity of the upper extremity. The degree of spasticity was measured by the Modified Ashworth Scale (grade 0-4). Severity of the pain level was determined using the Numeric Rating Scale (NRS, score 0-10). Also, patient satisfaction of the post-operative outcome was assessed. Results : Comparing the preoperative and postoperative spasticity using the Modified Ashworth Scale, we observed improvement in all patients, particularly in five of the nine patients (55.6%) who improved by three grades over an average of 66.4 months (range, 40-96). Regarding patient satisfaction, seven patients (77.8%) had affirmative results. None of the patients experienced severe, life-threatening, postoperative complications. We observed a decrease in the intensity of painful spasms to less than three scores as measured by NRS in all four patients with associated pain. Conclusion : This study shows that MDT provides significant, long-term reduction of harmful spasticity and associated pain in the upper limbs.

• Nutrition Research and Practice
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• 제6권2호
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• pp.155-161
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• 2012

Excessive oxidative stress and abnormal blood lipids may cause chronic diseases. This risk can be reduced by consuming an antioxidant- and fiber-rich vegetarian diet. We compared biomarkers of oxidative stress, antioxidant capacity, and lipid profiles of sex- and age-matched long-term vegetarians and omnivores in Korea. Forty-five vegetarians (23 men and 22 women; mean age, $49.5{\pm}5.3$ years), who had maintained a vegetarian diet for a minimum of 15 years, and 30 omnivores (15 men and 15 women; mean age, $48.9{\pm}3.6$ years) participated in this study. Their 1-day, 24-h recall, and 2-day dietary records were analyzed. Oxidative stress was measured by the levels of diacron reactive oxygen metabolites (d-ROM). Antioxidant status was determined by the biological antioxidant potential (BAP) and levels of endogenous antioxidant enzymes such as superoxide dismutase, catalase, and glutathione peroxidase. We observed that vegetarians had a significantly lower body fat percentage ($21.6{\pm}6.4%$) than that of omnivores ($25.4{\pm}4.6%$; $P$ < 0.004). d-ROM levels were significantly lower in vegetarians than those in omnivores ($331.82{\pm}77.96$ and $375.80{\pm}67.26$ Carratelli units; $P$ < 0.011). Additionally, total cholesterol levels in the vegetarians and omnivores were $173.73{\pm}31.42$ mg/dL and $193.17{\pm}37.89$ mg/dL, respectively ($P$ < 0.018). Low-density lipoprotein cholesterol was $101.36{\pm}23.57$ mg/dL and $120.60{\pm}34.62$ mg/dL ($P$ < 0.005) in the vegetarians and omnivores, respectively, indicating that vegetarians had significantly lower lipid levels. Thus, oxidative stress, body fat, and cholesterol levels were lower in long-term vegetarians than those in omnivores.

• Kidney Research and Clinical Practice
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• 제36권3호
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• pp.257-263
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• 2017

Background Rituximab (RTX) can be used as a rescue therapy for steroid-dependent nephrotic syndrome (SDNS). However, the efficacy and safety of long-term, repeated use of RTX are not established. This study was conducted to assess the efficacy and safety of long-term, repeated RTX treatment in children. Methods Eighteen consecutive child patients with SDNS who were treated with three or more cycles of RTX for one year or longer were recruited, and their medical records were retrospectively reviewed. Results The patients were followed for $4.7{\pm}1.9years$ and received $5.2{\pm}2.3cycles$ of RTX over $2.8{\pm}1.1years$. Approximately 70% of the additional RTX cycles were administered due to recovery of B-cells without relapse. The relapse rate decreased from $3.4{\pm}2.0per$ year initially to $0.4{\pm}0.8per$ year at the third year after RTX treatment. Approximately 10% of the RTX infusions were accompanied by mild infusion reactions. Eight patients showed sustained remission without any oral medication after the last cycle of RTX, while 10 patients had one or more episodes of relapse after the last cycle of RTX. The relapse rate in the latter group decreased from $2.8{\pm}1.5per$ year before RTX treatment to $1.3{\pm}0.8per$ year after cessation of RTX treatment. No significant differences in clinical parameters were found between the two groups. Conclusion This retrospective study showed that pre-emptive and long-term, repeated RTX treatment is relatively effective and safe in children with SDNS. However, well-designed prospective studies are needed to confirm these findings.

• 대한조현병학회지
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• 제23권1호
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• pp.38-44
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• 2020

Objectives: Dehospitalization of long-term inpatients with schizophrenia can be difficult because of complex factors such as chronic symptoms and low family and social support. The aim of this study was to identify factors related to dehospitalization and readmission of long-term inpatients with schizophrenia. Methods: This retrospective study reviewed the medical records of patients discharged from a psychiatric hospital in Yongin, South Korea, from February 1, 2016, to July 31, 2017. Patients who were hospitalized for over 3 months were divided into two groups: readmission (n=47) and dehospitalization (n=55). Differences in sociodemographic and clinical factors were analyzed between the two groups. Results: Regarding sociodemographic characteristics, female sex, familylessness, discharge to nursing homes, and discharge after symptom improvement were more prevalent in the dehospitalization group, whereas male sex, having a sibling as next of kin, and discharge because of other problems were more prevalent in the readmission group. Among clinical characteristics, hospital stay was longer in the readmission group. Conclusion: In this study, patients without a family showed a tendency to not be readmitted when they were discharged to nursing homes after symptom improvement. Expansion of social welfare support may encourage dehospitalization of long-term inpatients with schizophrenia.

• Korean Journal of Radiology
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• 제23권10호
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• pp.998-1008
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• 2022

Objective: The present study aimed to assess the relationship between incidental abnormalities on thoracic computed tomography (CT) and mortality in a general screening population using a long-term follow-up analysis. Materials and Methods: We retrospectively collected the medical records and CT images of 840 participants (mean age ± standard deviation [SD], 58.5 ± 6.7 years; 564 male) who underwent thoracic CT at a single health promotion center between 2007 and 2010. Two thoracic radiologists independently reviewed all CT images and evaluated any incidental abnormalities (interstitial lung abnormality [ILA], emphysema, coronary artery calcification [CAC], aortic valve [AV] calcification, and pulmonary nodules). Kaplan-Meier analysis with log-rank and z-tests was performed to assess the relationship between incidental CT abnormalities and all-cause mortality in the subsequent follow-up. Cox proportional hazards regression was performed to further identify risk factors of all-cause mortality among the incidental CT abnormalities and clinical factors. Results: Among the 840 participants, 55 (6%), 171 (20%), 288 (34%), 396 (47%), and 97 (11%) had findings of ILA, emphysema, CAC, pulmonary nodule, and AV calcification, respectively, on initial CT. The participants were followed up for a mean period ± SD of 10.9 ± 1.4 years. All incidental CT abnormalities were associated with all-cause mortality in univariable analysis (p < 0.05). However, multivariable analysis further revealed fibrotic ILA as an independent risk factor for all-cause mortality (hazard ratio, 2.52 [95% confidence interval, 1.02-6.22], p = 0.046). ILA were also identified as an independent risk factor for lung cancer or respiratory disease-related deaths. Conclusion: Incidental abnormalities on screening thoracic CT were associated with increased mortality during the long-term follow-up. Among incidental CT abnormalities, fibrotic ILA were independently associated with increased mortality. Appropriate management and surveillance may be required for patients with fibrotic ILA on thoracic CT obtained for general screening purposes.

• 한국문헌정보학회지
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• 제47권1호
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• pp.105-124
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• 2013

국내 대통령기록물의 연구 및 활용, 서비스를 위해서는 다양한 대통령기록물의 유형과 포맷에 대한 통합 메타데이터 설계 및 운영이 필요하며, 상이한 메타데이터 구조를 가지고 있는 대통령기록관과 민간 대통령도서관 기념관의 메타데이터 표준화가 요구된다. 이에 이 연구에서는 국내 대통령기록물의 메타데이터 통합 운영을 위하여 통합 메타데이터 설계 원칙과 메타데이터 속성 및 관계를 제안하였다. 메타데이터 설계 원칙은 '대통령기록물 간의 관계 설정 및 설계', '다중 개체 모형을 적용한 대통령기록물 각 개체별 설계', '다양한 유형의 대통령기록물을 기술할 수 있도록 설계', '소장기관의 업무 전주기를 반영한 메타데이터 설계', '하이브리드형 장기보존 메타데이터 설계'이다. 메타데이터 요소는 모든 유형의 대통령기록물들이 공통적으로 지니고 있는 공통속성 요소, 특정 대통령기록물만이 갖는 고유속성 요소, 대통령기록물 생산에 관련된 타 기록물간의 연관 및 참조정보 요소이다.

• 한국기록관리학회지
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• 제15권1호
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• pp.89-125
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• 2015

본 연구의 목적은 도큐멘테이션 전략을 활용하여 역대 대통령기록물의 부족한 부분을 보완하고 대통령이 국정을 운영하는데 있어 참고자료가 될 수 있도록 장기적으로 대통령기록물 수집이 가능한 방안을 마련하는 것이다. 이를 위해 문헌연구, 국외 사례분석, 미국과 한국 대통령기록물 수집 사례를 살펴보았으며 국내 대통령기록물 수집과 관련하여 심층면담을 실시하였다. 심층면담은 반구조화 질문지로 구성하였고, 대상기관은 기관별로 재단 및 기념 사업회, 중앙행정기관, 대학부설기관 등 15개 기관으로 구분하여 선정하였다. 인터뷰 참여자는 총 15개 기관 17명(100%) 중에서 12개 기관 14명(82%)이며 인터뷰 결과는 질적 연구방법론의 근거이론방법에 따라 분석하였다. 이러한 인터뷰 결과를 바탕으로 대통령기록물을 수집하는 방안으로 도큐멘테이션 전략을 활용하여 수집 전략을 설계하고, 운영하며, 홍보하는 모형을 제안하였다.

• 한국기록관리학회지
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• 제22권4호
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• pp.175-196
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• 2022

본 연구는 연구자가 부여한 논문의 키워드 분석을 통해 기록보존 분야의 연구동향을 밝히고 시간의 경과에 따른 기록보존 분야 연구 주제의 변천과정을 파악하고자 하였다. 2000년부터 2021년까지 국내 학술지에 게재된 기록보존 연구 463편을 중심으로 NetMiner V.4를 통해 연결 중심성 분석과 매개 중심성 분석을 수행하였다. 수집한 연구논문을 학술지 게재 시기에 따라 제1구간(2000년~2007년), 제2구간(2008년~2014년), 제3구간(2015년~2021년)으로 나누어 분석하였다. 분석결과 전 구간에서는 '전자기록'과 '장기보존', 제1구간에서는 'OAIS참조모형', 제2구간에서는 '전자기록', 제3구간에서는 '기록관리기준표'과 '장기보존'이 핵심 주제 키워드로 영향력과 확장성이 높은 것으로 나타났다. 제1구간에서 '디지털 보존', '디지털화', 'OAIS참조모형' 등 기록보존을 위한 개념적 틀과 이론 중심 연구, 제2구간에서 '전자기록', '평가', 'DRAMBORA' 등 보존 활동과 관련된 절차와 실제 적용 중심 연구, 제3구간에서 '데이터세트', '행정정보시스템', '소셜미디어' 등 기록관리 환경 변화에 따른 기술적 구현 연구 주제로 진행되는 과정을 확인하였다.

• 한국기록관리학회지
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• 제13권2호
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• pp.115-147
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• 2013

본 연구는 표준 RMS를 대상으로 보존 기능 구현 여부와 그 방식을 확인해보고 이후 보존 기능 개선을 위한 고려해야 할 시사점을 도출하였다. 법률과 공공표준 분석을 통해 기록관에서 이루어지는 공공 전자기록 보존 활동을 추출하고, 이를 바탕으로 표준 RMS가 구현하였다 밝힌 보존 기능과의 예비 평가를 실시하였다. 그 결과 표준 RMS는 기록관에서 이루어지는 전자기록 보존 기능의 대부분을 포맷변환에 할당하고 있음이 드러나 이 연구에서도 포맷변환 기능으로 한정하여 평가하는 것으로 축소하였다. 조정된 범위에 맞게 평가에 이용할 체크리스트를 작성한 후, 이를 활용하여 표준 RMS의 보존 기능을 사용한 경험이 있는 기관의 기록물관리 전문요원을 대상으로 면담을 진행하였다. 그 결과, 표준 RMS는 기능 구현의 측면에서는 일정 정도 긍정적으로 평가될 수 있으나 기능의 이용편의성 등과 같은 구현 방식은 기록물 전문요원의 업무를 효율적으로 지원하기 힘든 것으로 드러났다. 이에 이후 표준 RMS의 보존 기능 개선상 고려해야 할 사항을 제안하였다.