• Radiation Oncology Journal
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• v.3 no.1
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• pp.51-58
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• 1985

This study analyzes fifteen patients who underwent a course of radiation therpy for their vulva cancer in the Department of Radiation Oncology, College of Medicine, Yonsei University from January, 1971 to April, 1985. Four patients had initial surgery for their vulva cancer and were subsequently treated by a course of adjuvant radiation therapy. Eleven patients were given radiation therapy as the initial course of therapy, and one of these was in adjuvant setting before radical surgery. Treatment in each instance was individuilzed and usually consisted of some components of external beam, brachytherapy, and/or electron beam therapy. Primary local control rate in all cases was $53\%(8/15),\;40\%(4/10)$ in the radiation therapy alone group and $80\%(4/5)$ in the radiation therapy combined with surgery group. Treatment failures were noted in 7/10 in the radiation therapy alone group and 2/5 in the radiation therapy combined with surgery group. The most common failure site was primary site failure(vulva).

• Radiation Oncology Journal
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• v.7 no.2
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• pp.149-156
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• 1989

Multicellular tumor spheroids of HeLa cells have been grown in a static culture system. Samples of spheroids were exposed for 2 h to graded concentration of cis-platinum and its analogue, carboplatin, and then response assayed by survival of clonogenic cells. The purpose of present experiment is to clarify the effectiveness of these platinum compounds and to evaluate intrinsic radiosensitivity of cells using spheroids of HeLa cells as an experimental in vitro model. Variations of the drug sensitivity of monolayers as well as spheroids were also evaluated in cell-survival curves. In cis-platinum concentration-survival curve, there was a large shoulder extending as far as $Cq=3.4{\mu}M$, after which there was exponential decrease in survival curve having a Co Value of $1.2{\mu}M$ in spheroids. While the Co for the spheroids was essentially no significant change, but Cq value was larger than that of monolayers. This suggest that the effect of cis-platinum is greater En the monolayer with actively proliferaing cells than hypoxic one. In the carboplatin concentration-survival curves, the Co value of spheroids was $15.0{\mu}M$ and the ratio with the Co from monolayer cell $(32.5{\mu}M)$ was 0.40, thus indicating that the spheroids had a greater sensitivity to carboplatin than monolayers. Therefore, the effect of carboplatin is mainly on the deeper layers of spheroids acting as hypoxic cell sensitizer. The enhanced effect was obtained for monolayer cells using combined X-ray and carboplatin treatment 2 hours before irradiation. The result shown in isobologram analysis for the level of surviving fraction at 0.01 indicated that the effect of two agents was trusty supra-additive. From this experimental data, carboplatin has excited much recent interest as one of the most promising, since it is almost without nephrotoxicity and causes less gastrointestinal toxicity than cis-platinum. Interaction between carboplatin and radiation might play an important role for more effective local tumor control.

• Radiation Oncology Journal
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• v.9 no.2
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• pp.233-239
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• 1991

This is a retrospective study of 62 patients with unresected squamous cell carcinoma of the esophagus treated by radiotherapy alone (25 patients) or combined chemotherapy and radiotherapy (37 patients). Of these, 14 of 25 patients treated by radiation therapy alone and 25 of 37 patients treated by combined chemotherapy and radiotherapy completed radiotherapy consisting of 55 to 60 Gy in 5 to 6 weeks and were analyzed for local control rate and survival rate. Follow up ranged from 6 days to 58 months. Three ($8\%$) of 39 patients had a complete response, twenty-eight ($72\%$) a partial response and eight ($20\%$) minimal or no response. Overall median survival was 11 months for all stages. The 1 year and 2 year actuarial survival rates were $48.6\%$ and $13\%$ respectively. Age and stage had prognostic significances (p <0.05, p<0.05 respectively). The 1 year survival rate was $70.1\%$ for stage I, $47.6\%$ for stage II, and $28.4\%$ for stage III. The median survival was 19 months for stage I, 11 months for stage II, 6 months for stage III, and 5.5 months for stage III with distant metastases. The 1 year survival rate of patients 55 years and above was $69.6\%$, 54 years and below was $0\%$. There was no significant difference in survival rate between treatment modalities, locations of tumor, and responses of tumor.

• Journal of Food Hygiene and Safety
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• v.27 no.4
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• pp.456-460
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• 2012

This study was carried out as a survey on the level of lead (Pb), cadmium (Cd), arsenic (As) and mercury (Hg) in 5 items of agricultural products (lettuce, pumpkin, head lettuce, cabbage and crown daisy) for which safety guidelines are not yet established in Korea. The 407 samples were collected from local markets in 9 regional places and the levels of metals were measured by ICP-MS and mercury analyzer. The average levels of Pb, Cd, As and Hg were 0.026, 0.018, 0.008 and 0.003 mg/kg for lettuce, 0.002, 0.001, 0.001 and 0.0006 mg/kg for pumpkin, 0.002, 0.005, 0.001 and 0.0005 mg/kg for head lettuce, 0.001, 0.002, 0.0002 and 0.0006 mg/kg for cabbage and 0.022, 0.014, 0.006 and 0.004 mg/kg for crown daisy. For risk assessment, the daily dietary exposures of Pb, Cd and Hg by intake of these agricultural products were calculated and compared with PTWI (provisional tolerable weekly intake) established by JECFA. The daily dietary exposure of heavy metals by intake of these agricultural products were 0.13, 0.56 and 0.09% of PTWI, respectively. These monitoring results will be utilized as fundamental data for the establishment of Korean standards of Pb, Cd, As and Hg in 5 items of agricultural products and valuable source for DB construction for science-based safety control of heavy metals in foods including agricultural products.

• Fire Science and Engineering
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• v.31 no.5
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• pp.78-86
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• 2017

Disasters in South Korea are taking on more diverse and intricate aspects than before, while being affected by the industrial development and deterioration of the cities. Therefore, it is urgently needed for success in disaster countermeasures to secure emergency communications operating system which would make it possible to share various information between the control tower and field personnel quickly and accurately. This study proposes a method of improving the national emergency communications operating system based on the Federal disaster management system, emergency communications system, and Standard Operating Procedures (SOPs) employed in the US, which is the leading country in the field of disaster management. First, the organization of the emergency communications needs to be more systematized than in the past. The organization of the emergency communications of the central and local governments have to be administered according to their different roles and objectives. Furthermore, they must cooperate with each other based on interoperability. Second, emergency communications councils need to be established, composed of representatives related to disasters, and national and regional units need to be formed and operated separately. Third, the SOPs should not only cover both the operational and technical elements, but also assign the roles and responsibilities to the members of the disaster communications system. These improvements will assure the correct functioning of the disaster communications system in the field, which is expected to increase the probability of success in disaster countermeasures.

• Journal of Korea Multimedia Society
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• v.12 no.8
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• pp.1109-1119
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• 2009

WLAN(Wireless Local Area Network) standard is currently developing with increased wireless internet demand. Though existing IEEE 802.11e demonstrates that data rates exceed 54Mbps with assuring QoS(Quality of Service), wireless internet users can't be satisfied with real communication system. After IEEE 802.11e system, Study trends of IEEE 802.11n show two aspects, enhanced system throughput using aggregation among packets in MAC (Medium Access Control) layer, and better data rates adapting MIMO(Multiple-Input Multiple-Output) in PHY(Physical) layer. But, no one demonstrates IEEE 802.11n system performance results considering MAC and PHY connection. Therefore, this paper adapts MIMO in PHY layer for IEEE 802.11n system based on A-MPDU(Aggregation-MAC Protocol Data Unit) method in MAC layer considering MAC and PHY connection. SVD(Singular Value Decomposition) method with WLAN MIMO TGn Channel is used to analyze MIMO. Consequently, Simulation results show enhanced throughput and data rates compared to existing system. Also, We use Ns-2(Network Simulator-2) considering MAC and PHY connection for reality.

• Journal of the Korean Society of Food Science and Nutrition
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• v.44 no.6
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• pp.944-950
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• 2015

The purpose of this study was to provide a basis for the management of traditional Doenjang by analyzing characteristics of volatile compounds in local Doenjang certified as a traditional food. The main compounds in Doenjang were acids, esters, aldehydes, and pyrazines, whereas relatively high intensities of acetic acid, ethyl alcohol, benzaldehyde, ethyl acetate, ethyl 2-methyl butanoate, 2,5-dimethyl pyrazine, and tetramethylpyrazine were detected among identified compounds. The analysis revealed that the composition of basic volatile compounds in Doenjang was similar, but isovaleric acid, 2-methylbenzaldehyde, tetramethylpyrazine, benzaldehyde, ethyl alcohol, ethyl caprylate, furfural and butanoic acid can serve as marker compounds for quality evaluation since they were specifically abundant in only some kinds of Doenjang. As a result, the quality status of Doenjang certified as a traditional food was determined by constructing a database of the volatile compounds, which can be suggested as a quality control method.

• Journal of the Korean Society of Food Science and Nutrition
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• v.36 no.12
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• pp.1497-1502
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• 2007

The antioxidant effect of Korean cabbage kimchi containing 20% of sea tangle (SK) was studied in the rats fed with high fat diet (HFD) for 8 weeks. The rats (n=40) were divided into four experimental groups as a high fat diet group (HFD), HFD supplemented either with Korean cabbage kimchi used as experimental control (HCK), with SK (HSK), or with J-kimchi (HJK) that was purchased at the local market. The amount of kimchi supplemented was 10%. DPPH radical scavenging activities of SK were significantly higher than those of CK. Kimchi suppressed the hepatic lipid peroxidation significantly, especially by HSK (p<0.05). Inhibition of thiobarbituric acid reactive substances (TBARS) formation in HSK was the greatest among the kimchi groups (p<0.05). The activities of $Cu{\cdot}Zn$-superoxide dismutase (SOD), Mn-SOD and catalase decreased significantly (p<0.05) by kimchi supplementation. SOD and catalase activities of HSK were found to be the lowest among the kimchi groups. The decreased enzyme activity in kimchi group might be due to the less amount of lipid peroxides produced in the rats fed kimchi diet. The lowest antioxidative enzyme activities observed in HSK were in line with those of hepatic POV and TBARS of HSK. Our findings confirmed that kimchi acted as an antioxidant in the high fat fed rats and its antioxidant effect was significantly increased by the addition of sea tangle.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.11 no.6
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• pp.95-102
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• 2012

In this paper, we propose a method that can construct efficiently a P2P overlay multicast network composed of many heterogeneous peers in communication bandwidth, processing power and a storage size by selecting a peer in a distributed fashion using an ant-colony theory that is one of the computational intelligence methods. The proposed method considers not only the capacity of a peer but also the number of children peers supported by the peer and the hop distance between a multicast source and the peer when selecting a parent peer of a newly joining node. Thus, an P2P multicast overlay network is constructed efficiently in that the distances between a multicast source and peers are maintained small. In addition, the proposed method works in a distributed fashion in that peers use their local information to find a parent node. Thus, compared to a centralized method where a centralized server maintains and controls the overlay construction process, the proposed method scales well. Through simulations, we show that, by making a few high capacity peers support a lot of low capacity peers, the proposed method can maintain the size of overlay network small even there are a few thousands of peers in the network.

• Journal of the Institute of Electronics and Information Engineers
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• v.52 no.4
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• pp.135-144
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• 2015

Fingerprint pores have proven to be useful features for fingerprint recognition and several pore-based fingerprint recognition systems have been reported recently. In order to recognize fingerprints using pore information, it is very important to extract pores reliably and accurately. Existing pore extraction methods utilize 2D model fitting to detect pore centers. This paper proposes a pore extraction method using 1D Gaussian model which is much simpler than 2D model. During model fitting process, 1D model requires less computational cost than 2D model. The proposed method first calculates local ridge orientation; then, ridge mask is generated. Since pore center is brighter than its neighboring pixels, pore candidates are extracted using a $3{\times}3$ filter and a $5{\times}5$ filter successively. Pore centers are extracted by fitting 1D Gaussian model on the pore candidates. Extensive experiments show that the proposed pore extraction method can extract pores more effectively and accurately than other existing methods, and pore matching results show the proposed pore extraction method could be used in fingerprint recognition.