• 대한전기학회:학술대회논문집
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• 대한전기학회 1996년도 하계학술대회 논문집 B
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• pp.1182-1185
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• 1996

The objective of this paper is to control a nonlinear dynamical systems based on Self-Organized Distributed Networks (SODN). The learning with the SODN is fast and precise. Such properties are caused from the local learning mechanism Each local network learns only data in a subregion. Methods for indirect adaptive control of nonlinear systems using the SODN is presented. Through extensive simulation, the SODN is shown to be effective for adaptive control of nonlinear dynamic systems.

• Asian-Australasian Journal of Animal Sciences
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• 제32권7호
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• pp.922-929
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• 2019

Objective: Mutations in low-density lipoprotein receptor (LDLR), which encodes a critical protein for cholesterol homeostasis and lipid metabolism in mammals, are involved in cardiometabolic diseases, such as familial hypercholesterolemia in pigs. Whereas microRNAs (miRNAs) can control LDLR regulation, their involvement in circulating cholesterol and lipid levels with respect to cardiometabolic diseases in pigs is unclear. We aimed to identify and analyze LDLR as a potential target gene of SSC-miR-20a. Methods: Bioinformatic analysis predicted that porcine LDLR is a target of SSC-miR-20a. Wild-type and mutant LDLR 3'-untranslated region (UTR) fragments were generated by polymerase chain reaction (PCR) and cloned into the pGL3-Control vector to construct pGL3 Control LDLR wild-3'-UTR and pGL3 Control LDLR mutant-3'-UTR recombinant plasmids, respectively. An miR-20a expression plasmid was constructed by inserting the porcine premiR-20a-coding sequence between the HindIII and BamHI sites in pMR-mCherry, and constructs were confirmed by sequencing. HEK293T cells were co-transfected with the miR-20a expression or pMR-mCherry control plasmids and constructs harboring the corresponding 3'-UTR, and relative luciferase activity was determined. The relative expression levels of miR-20a and LDLR mRNA and their correlation in terms of expression levels in porcine liver tissue were analyzed using reverse-transcription quantitative PCR. Results: Gel electrophoresis and sequencing showed that target gene fragments were successfully cloned, and the three recombinant vectors were successfully constructed. Compared to pMR-mCherry, the miR-20a expression vector significantly inhibited wild-type LDLR3'-UTR-driven (p<0.01), but not mutant LDLR-3'-UTR-driven (p>0.05), luciferase reporter activity. Further, miR-20a and LDLR were expressed at relatively high levels in porcine liver tissues. Pearson correlation analysis revealed that porcine liver miR-20a and LDLR levels were significantly negatively correlated (r = -0.656, p<0.05). Conclusion: LDLR is a potential target of miR-20a, which might directly bind the LDLR 3'-UTR to post-transcriptionally inhibit expression. These results have implications in understanding the pathogenesis and progression of porcine cardiovascular diseases.

• 대한의용생체공학회:의공학회지
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• 제30권4호
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• pp.311-317
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• 2009

An automatic control system is proposed and implemented for a miniaturized DNA extraction system using magnetic bead. A host-local system is employed for the accommodation of the graphical user interface and the basic control function. The functional partitioning into the local and the host system is discussed. The control functions are classified and formalized for the flexible control scenario, which is the input of the proposed system. As the proposed scenario is consists of the sequence of the user-centric actions, the user goal can be easily programmed and modified. The DNA extraction performance of the implemented system was compared with the existing silica-membrane-based method, resulting in the comparable concentration and purity of the extracted DNA. The proposed system is currently being utilized for the development of the DNA extraction system only changing scenario, without any alteration of the system.

• 한국지능시스템학회논문지
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• 제9권6호
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• pp.605-614
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• 1999

본 논문에서는 단일 입력 단일 출력을 갖는 복잡한 비선형 시스템을 위한 퍼지 제어 시스템의 설계 및 분석을 제시한다. 제안된 방법은 주어진 비선형 시스템의 지역적인 동특성을 표현하기 위해 퍼지 모델을 구성하여 이를 바탕으로 제어기를 구성한다. 전체 시스템을 총괄하는 제어기는 각 지역 퍼지 모델에 대한 보상기와 슬라이딩 모드 제어 이론을 사용한 전역 피드포워드 제어기를 사용하여 구성한다. 따라서 제안된 제어기는 퍼지 모델 기반 제어방법과 슬라이딩 모드 제어 방법의 장점을 동시에 취하여 기존의 퍼지 모델 기반 제어기와 달리 공통 리아프노프 행렬을 구하지 않고서 안정성을 증명할 수 있으며 향상된 성능 및 추종 성능을 보인다. 또한 제안된 제어방법은 기존의 퍼지 모델기반 제어 방법과는 달리 원 비선형 시스템에 대한 안정도의 해석이 가능하다. 제안된 방법의 우수성과 유효성을 보이기 위해 두가지 수치 예제를 제공한다.

• Advances in pediatric surgery
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• 제20권1호
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• pp.7-11
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• 2014

The present study compared the postoperative analgesic effects of ilioinguinal and iliohypogastric nerve block with infiltration of local anesthetics (bupivacaine) into the wound in children after inguinal hernia repair. Ninety children below 7 years old who were scheduled elective inguinal hernia repair were randomly allocated into one of three groups. The patients in nerve block (NB) group, ilioinguinal and iliohypogastric nerve block was done with 0.5 mL/kg of 0.25% bupivacaine. The patients in infiltration of local anesthetics (LI) group, 0.5 mL/kg of 0.25% bupivacaine was infiltrated into the wound after surgery. The patients in control group were allocated as a Control group. Postoperative pain was assessed at 1, 3, 5, and 24 hours after operation with FLACC scale and additional analgesic consumption were counted. The three groups were not significantly different in age, sex, body weight, and duration of operation. Pain scores at 1 hour and 3 hours after operation were significantly higher in Control group than in NB group and LI group (p<0.01), whereas there were no difference between NB group and LI group. The rescue analgesics administration was significantly higher in Control group (n=11) than in NB group (n=6) and LI group (n=7) (p<0.05). There were 2 cases of transient femoral nerve palsy in NB group. Both of ilioinguinal and iliohypogastric nerve block and infiltration of local anesthetics into the wound provided effective postoperative analgesia in early postoperative period following inguinal hernia repair in children. But no difference between the two methods. Technically, infiltration of local anesthetics into the wound was easier and safer than ilioinguinal and iliohypogastric nerve block.

• Journal of Korean Neurosurgical Society
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• 제38권1호
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• pp.35-40
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• 2005

Objective : Limited data are available concerning the outcome of the patients with atypical meningioma due to lack of the studies with large series. The authors review atypical meningioma retrospectively and analyzed various parameters concerning its outcome. Methods : Of the 866 meningioma patients treated between 1990 and 2003, pathologically proven 54 atypical meningiomas were reviewed. Various factors of the patients were analyzed, and surgical specimens were re-examined blindly by neuropathologist without any patient information. Extent of surgical resection was determined according to Simpson's classification by reviewing the chart and postoperative scan if possible. Results : Twenty-three [42.6%] had local recurrences during the follow-up, of which 13 [32.5%] of 40 complete excisions and 10 [71.4%] of 14 incomplete excisions. The median time to recurrence was 47 months, and the overall 3-, 5-, and 10-year local control rates were 62.4%, 41.5%, and 31.1%, respectively. Five [9.3%] died during follow-up period. The mean survival time was 123months, and the overall 3-, 5-, and 10-year survival rates were 94.2%, 87.2%, and 78.5%, respectively. The extent of surgical excision was the most significant prognostic factor not for survival but for local control [p=0.2179 and 0.0005, respectively]. Extracranial metastasis was not seen in our cases. Conclusion : Complete surgical excision is the most important factor in improving local control. Careful long-term follow-up is mandatory because atypical meningioma shows a broad range of aggressiveness and natural history.

• 대한간호학회지
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• 제34권6호
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• pp.924-933
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• 2004

Purpose: This study was to examine the effects of hand massage and hand holding as nursing interventions on the anxiety in patients with local infiltration anesthesia. Method: The design of this study was a nonequivalent, control group, non- synchronized design. The subjects of this study consisted of 15 patients for the hand massage group, 15 patients for the hand holding group and 17 patients for the control group awaiting surgery in the operation room of a general hospitalin Daegu. As an experimental treatment, hand massage was carried out by the Hand Massage Protocol developed by Snyder(1995) and interpreted by Cho(1998) and hand holding developed by Cho(1998). The data were analyzed by SPSS/WIN, T-test, ANOVA, Cronbach's a, and the Scheffe test. Results: The hand massage group and hand holding group were more effective than the control group in reducing anxiety, VAS score, systolic blood pressure and pulse rate. Conclusion: Hand massage and hand holding are effective nursing interventions that alleviates the psychological and physiological anxiety of patients with local infiltration anesthesia. In particular, the simple contact of hand holding is regarded as an effective and easily accessible nursing intervention in the operating room.

• 조명전기설비학회논문지
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• 제13권4호
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• pp.56-67
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• 1999

본 논문에서는, 퍼지 제어기의 성능에 대한 손실이 없으면서, 퍼지규칙의 수를 줄이고 최적화하고 자동화할 수 있는 방법으로 개략추론과 국소추론의 개념을 결합시킨 새로운 합성형 퍼지 추론법을 제안한다. 개략추론과 국소추론의 상호작용을 제어하기 위하여, DNA코딩 알고리즘을 합성형 퍼지 추론법의 국소퍼지 추론부에 도입한다. 그리고, 제안된 방법의 성능을 평가하기 위하여 실제의 수위제어 시스템에 적용하고, 시뮬레이션한 결과는 제안된 방법이 종래의 제어기법보다 고도의 제어 정밀성을 가지며, 퍼지규칙의 자동 획득도 용이함을 입증하였다.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 1992년도 한국자동제어학술회의논문집(국내학술편); KOEX, Seoul; 19-21 Oct. 1992
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• pp.513-518
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• 1992

We are now doing research for the drawing check of local parts in mechanical drawing made by a CAD system. It needs the recognition of drawing elements with respect to the local parts. Because, we usually abbreviate the dimensioning in the mutually related drawing elements. This paper is concerned with a computer aided supporting system to the dimension check and recognition of local parts in mechanical drawings. This sytem has been applied to some examples and we have confirmed the feasibility of this checking method.

• 한국콘텐츠학회논문지
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• 제14권10호
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• pp.112-123
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• 2014

본 논문은 천안시 공무원들의 인식조사를 통해 지방자치단체의 재정건전성 확보방안을 마련하는데 목적이 있다. 선행연구를 분석해본 결과, 지방정부의 재정건전성은 자치단체를 둘러싸고 있는 사회, 경제, 인구, 정치 등 다양한 요인들에 의해 복합적으로 영향을 받고 있음을 발견하였다. 본 연구는 이러한 논의를 바탕으로 자치단체의 재정실태관련 지표, 재정건전성 관련 지표, 재정건전성을 높이기 위한 지표를 도출했다. 천안시의 재정 건전성을 확보하기 위해서는 재정운영의 효율성을 높여야 한다. 재정운영 효율성을 높이기 위해서는 지역주민의 재정감시 및 통제 장치 마련, 투자심사분석제도 활성화 등이 필요하다. 또한 효율적인 채무관리를 위해서는 자치단체의 자율적인 통제기능이 강화되어야 한다. 지방 재정의 확충을 위해 국고보조사업의 지방비 부담을 인하해야하며, 사용료 요율의 현실화가 필요하다. 지방재정운영의 발전은 중앙정부, 지방정부, 지역주민의 연계망 속에서 자율과 통제의 조화 통해 이루어져야 한다. 또한 계획수립-자원배분-평가-환류시스템을 체계적으로 구축하여 재원이 실질적으로 주민복지향상 및 지역개발투자에 배분될 수 있도록 해야 한다.