• Title/Summary/Keyword: local control

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Preoperative Long Course Chemoirradiation in a Developing Country for Rectal Carcinoma: Kuala Lumpur Hospital Experience

  • Lee, Wei Ching;Yusof, Mastura Md.;Lau, Fen Nee;Ee Phua, Vincent Chee
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.6
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    • pp.3941-3944
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    • 2013
  • Background: The use of preoperative chemoirradiation is the commonest treatment strategy employed in Malaysia for locally advanced rectal cancer. We need to determine the local control and survival rates for comparison with established rates in the literature. Materials and Methods: This retrospective study analyzed all newly diagnosed patients with rectal adenocarcinoma who underwent long course preoperative radiotherapy (RT) at the Department of Radiotherapy and Oncology, Kuala Lumpur Hospital (HKL) between $1^{st}$ January 2004 and $31^{st}$ December 2010. The aim of the study was to determine the radiological response post radiotherapy, pathological response including circumferential resection margin (CRM) status, 3 years local control, 3 years overall survival (OS) and 3 years disease free survival (DFS). Statistical analysis was performed using the SPSS software. Kaplan-Meier and log rank analysis were used to determine survival outcomes. Results: A total of 507 patients with rectal cancer underwent RT at HKL. Sixty seven who underwent long course preoperative RT were eligible for this study. The median age at diagnosis was 60 years old with a range of 26-78 years. The median tumour location was 6 cm from the anal verge. Most patients had suspicion of mesorectum involvement (95.5%) while 28.4% of patients had enlarged pelvic nodes on staging CT scan. All patients underwent preoperative chemo-irradiation except for five who had preoperative RT alone. Only 38 patients underwent definitive surgery (56.7%). Five patients were deemed to be inoperable radiologically and 3 patients were found to have unresectable disease intraoperatively. The remaining 21 patients defaulted surgery (31.3%). The median time from completion of RT to surgery was 8 weeks (range 5.6 to 29.4 weeks). Fifteen patients (39.5%) had surgery more than 8 weeks after completion of RT. Complete pathological response was noted in 4 patients (10.5%). The pathological CRM positive rate after RT was 18.4%. With a median follow-up of 38.8 months, the 3 year local control rate was 67%. The 3 years rate for CRM positive (<2 mm), CRM clear (>2 mm) and pCR groups were 0%, 88.1% and 100% respectively (p-value of 0.007). The 3 year OS and DFS were 57.3% and 44.8% respectively. Conclusions: In conclusion, the approach of long course preoperative chemoirradiation for rectal cancer needs to be re-examined in our local setting. The high rate of local recurrence is worrying and is mainly due to patient defaulting post-preoperative chemoirradiation or delayed definitive surgery.

Interactive Roles of Local versus Global Primed Identity and Advertisement Framing on Brand Evaluation (브랜드평가에 대한 아이덴티티의 점화와 광고프레임의 상호작용효과)

  • Choi, Nak Hwan;Liu, Cong
    • Science of Emotion and Sensibility
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    • v.16 no.1
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    • pp.11-28
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    • 2013
  • This article aims to explore the interactive roles of types of primed identity (local versus global identity) and types of ad framing on brand evaluations. The authors designed 2 experiments in which each experiment followed a $2{\times}2$ between-subject design. The empirical results showed that a gain-framed ad induced more positive emotional responses than a loss-framed ad, and the positive affective responses lead to more favorable brand evaluation. Furthermore, the results showed that there were interactive effects of primed identity and types of advertisement frame on brand evaluation. In the additional analysis, the results showed that when people with local identity were exposed to the gain-framed ad, they would engage in a higher level of integration processing than those in the control group, which in turn induced more favorable evaluation to the local brand. That is, the integration processing mode played a mediating role between the interaction (local id priming ${\times}$ ad frame) and the local brand evaluation. However, in the case of global brand evaluation, the integration processing mode did not play such a mediating role.

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The Impact of Underdog Positioning on Consumer Preference in Korea: Focusing on Local Service Providers

  • Bang-Wool Han
    • Journal of Korea Trade
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    • v.26 no.5
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    • pp.76-87
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    • 2022
  • Purpose - Small independent brands from local companies often use underdog positioning to compete with established global brands. However, whether the effectiveness of underdog positioning of local businesses in the service sector remains insufficient. The purpose of this paper is to investigate the underdog effect on the preference of Korean consumers for individual service providers positioned as underdogs. Design/methodology - The author examines the research question of this study using a one-way ANOVA in three different positioning (underdog vs. top dog vs. control) between-subjects design, with a group of Korean participants. Findings - The experimental study shows that support for independent local (vs. global) service providers positioned as underdogs is straightforward. Using the lens of consumer identification with underdog biographies, this study found that consumers prefer small local service providers with passion and determination regardless of their disadvantages. Originality/value - To the best of the author's knowledge, this is the first study to examine the effectiveness of underdog positioning in the context of individual service providers. As it competes with global service companies for domestic consumer preference in Korea, the findings have great implications for ensuring the sustainability of small local service providers.

The Determinants of Entrepreneurial Intentions in Local Brand Fashion: A Perspective from Vietnamese Youth.

  • Cuong NGUYEN;Tien HUYNH;Khanh HA
    • The Journal of Economics, Marketing and Management
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    • v.12 no.2
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    • pp.19-26
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    • 2024
  • In recent years, entrepreneurship has become a significant movement in Vietnam. Vietnamese youth has paid more attention on entrepreneurship. Local brand fashion is currently booming in Vietnam. Many young Vietnamese choose to start up in local brand fashion. Vietnamese government has show strong commitment to support entrepreneurial movement among young people. Purpose: The research focused on assessing the determinants of entrepreneurial intentions in local brands fashion in Vietnam. Research design, data and methodology: The sample size consist of 293 young Vietnamese who are passionate on starting up their business in fashion. The research method employ Exploratory Factor Analysis (EFA) and SPSS software is used to analysze the collected data. Data collection involved a mixed-methods approach, combining surveys and case studies. Results: The research findings confirm the determinants of entrepreneurial intentions in local brand fashions are Attitude towards behavior, Subjective norms, Cognitive behavioral control, Entrepreneurship education, and Capital. Conclusion: The study not only delved into the influencing elements for starting a business but also examined the current landscape of the youth-oriented local fashion brand market. Managerial implications are provided to promote entrepreneurial intention among young Vietnamese in fashion industry. Limitations and further research are also discussed to provide recommended research directions for future studies.

Power-based Supervisory Control of Discrete Event Systems: Political Economy Analysis (권력에 기초한 이산사건시스템의 관리제어: 정치경제학 해석)

  • Park, Seong-Jin
    • Journal of the Institute of Electronics and Information Engineers
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    • v.50 no.7
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    • pp.244-252
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    • 2013
  • In this paper, we show that supervisory control theory of discrete event systems can be applied to analyze the problem of power in political economy. For this purpose, we introduce the decision mechanism of control inputs based on power, and the consequent behavior of a supervised system. Specifically, this paper presents the notion of power-controllability as a necessary and sufficient condition to achieve a common control objective of competing groups (local controllers). If the power-controllability is met, a modular system controlled by local controllers with power functions is not deviated from a common control objective of them.

House Rent Control System and Its Implementation in France (프랑스 주택 임대료 규제 및 관련 제도 연구)

  • Lee, Seong-Keun;Choi, Min-Ah
    • Land and Housing Review
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    • v.9 no.4
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    • pp.1-9
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    • 2018
  • Since year 2000, French housing and rent prices rose at a rapid rate and the housing market has been overheated. Face to this phenomena, the French government enacted a new law Alur which is a legislatif tool to control the private housing rent price for the cities, where the tension of the housing market is very high. This new law has impacted the housing market in two major ways. First, for the 38 cities designated by this law, the rent price's increase rate can not rise above the IRL, which is the rent reference index. Secondly, this law also permits local authorities to control the housing rent's price following the concrete price guidance. Especially in Paris, the city applicated this method for private rental housing since 2015. This city classified its own area by 14 zones. Based on the market surveys of each sector, local authority made a guidance for private housing rent's price. The guideline is consisted of average prices, maxima and minima price by types, which is classified by the construction year, number of rooms and furnished or not. Therefore, this study aims to understand french housing rent's price control system and draw implementation for korean housing rent policies. This research is meaningful for it introduces recent foreign regislations which could be helpful to control the housing market in Korea.

A Study on the Design and Performance Evaluation Technology of Fieldbus Pneumatic Solenoid Valve/Sensor System (필드버스 공압 솔레노이드 밸브/센서시스템 설계 및 성능평가 특성해석)

  • Kim, D.S.;Hong, C.P.
    • Proceedings of the KSME Conference
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    • 2001.11a
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    • pp.865-870
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    • 2001
  • For pneumatic system control, we need a data transmission system with high speed and high reliability or information interchange between main computer and solenoid valves and I/O devices. This paper presents a set of design techniques for a data communication system that is mainly used for pneumatic system control. For this purpose, we first designed hardware modules for an interface between central control module and local node that handles the operation of solenoid valves. In addition we developed a communication protocol for construction of RS-485 based multidrop network, and this protocol is basically designed with a kind of polling technique. Finally we evaluated performance of the developed system. The field test results show that, even under high noise environment, the data transmission of 375Kbps rate is possible up to 1,000m without using repeater. In addition, the system developed in this research is proved to be used easily for extension of a communication network because of its module structure.

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The Usefulness of Stereotactic Radiosurgery for Radioresistant Brain Metastases

  • Kim, Hyool;Jung, Tae-Young;Kim, In-Young;Jung, Shin;Moon, Kyung-Sub;Park, Seung-Jin
    • Journal of Korean Neurosurgical Society
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    • v.54 no.2
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    • pp.107-111
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    • 2013
  • Objective : We investigated the effectiveness of stereotactic gamma knife Radiosurgery (GKR) for radioresistant brain metastases with the impact upon histology. Methods : Between April 2004 and May 2011, a total of 23 patients underwent GKR for 67 metastatic brain tumors from 12 renal cell cancers, 5 sarcomas and 6 melanomas. The mean age was 56 years (range, 18 to 79 years). Most of the patients were classified as the Radiation Therapy Oncology Group recursive partitioning analysis class II (91.3%). The synchronous metastasis was found in 6 patients (26.1%) and metachronous metastasis in 17 patients (73.9%). We analyzed the local control rate, intracranial progression-free survival (PFS) and overall survival (OS). Results : The mean tumor volume for GKR was 2.24 cc and the mean prescription dose was 19.4 Gy (range, 10 to 24) to the tumor margin. Out of metachronous metastases, the median duration to intracranial metastasis was 3.3 years in renal cell cancer (RCC), 2.4 years in melanoma and 1.1 years in sarcoma (p=0.012). The total local control rate was 89.6% during the mean 12.4 months follow-up. The six-month and one-year local control rate was 90.2% and 83% respectively. Depending on the pathology, the control rate of RCC was 95.7%, sarcoma 91.3% and melanoma 80.5% during the follow-up. The common cause of local failure was the tumor bleeding in melanoma. The median PFS and OS were 5.2 and 8.4 months in RCC patients, 6.5 and 9.8 months in sarcoma, and 3.8 and 5.1 months in melanoma. Conclusion : The GKR can be one of the effective management options for the intracranial metastatic tumors from the radioresistant tumors. The melanoma showed a poor local control rate compared to other pathologies because of the hemorrhage.

Learning Framework for Robust Planning and Real-Time Execution Control

  • Wang, Gi-Nam;Yu, Gang
    • Management Science and Financial Engineering
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    • v.8 no.1
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    • pp.53-75
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    • 2002
  • In this Paper, an attempt is made to establish a learning framework for robust planning and real-time execution control. Necessary definitions and concepts are clearly presented to describe real-time operational control in response to Plan disruptions. A general mathematical framework for disruption recovery is also laid out. Global disruption model is decomposed into suitable number of local disruption models. Execution Pattern is designed to capture local disruptions using decomposed-reverse neural mappings, and to further demonstrate how the decomposed-reverse mappings could be applied for solving disrubtion recovery problems. Two decomposed-reverse neural mappings, N-K-M and M-K-N are employed to produce transportation solutions in react-time. A potential extension is also discussed using the proposed mapping principle and other hybrid heuristics. Experimental results are provided to verify the proposed approach.

A Method for Local Collision-free Motion Coordination of Multiple Mobile Robots

  • Ko, Nak-Yong;Seo, Dong-Jin;Kim, Koung-Suk
    • 제어로봇시스템학회:학술대회논문집
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    • 2003.10a
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    • pp.1609-1614
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    • 2003
  • This paper presents a new method driving multiple robots to their goal position without collision. To consider the movement of the robots in a work area, we adopt the concept of avoidability measure. To implement the concept in collision avoidance of multiple robots, relative distance between the robots is proposed. The relative distance is a virtual distance between robots indicating the threat of collision between the robots. Based on the relative distance, the method calculates repulsive force against a robot from the other robots. Also, attractive force toward the goal position is calculated in terms of the relative distance. The proposed method is simulated for several cases. The results show that the proposed method steers robots to open space anticipating the approach of other robots. The proposed method works as a local collision-free motion coordination method in conjunction with higher level of task planning and path planning method for multiple robots to do a collaborative job.

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