• Journal of the Korean Institute of Rural Architecture
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• v.10 no.1
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• pp.1-9
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• 2008

The purpose of this study is to investigate and analyse the opinions of tourists and local commercial residents for remodelling of Youngwol Gossi-cave area so that to find the way how to activate it. Therefore this study has been focused on the opinions of tourists to visit it, local merchants to sell goods and foods and officers to take charge of the control office. The present conditions of Gossi-cave area are stagnated since the service level is low by the excessive competition among the local merchants. As a result, the inner troubles have arisen among the local merchants. Therefore firstly the sustainable and future-oriented remodelling development of Youngwol Gossi-Cave area is required. And then the basic remodelling plan of participant type to be centered with tourists and local residents as the central figures through local residents' ability strengthening must be established. Lastly the basic remodelling plan through the connection of surrounding tour resources and the resource increase of local amenities must be established. Also it is necessary for the conversion as a tour place of sojourn by supplying with various shows through connections among surrounding tour resources worthy of seeing and the creation of concept to provide the excitement through the education and experience in a basic remodelling plan direction of Youngwol Gossi-cave area.

• Journal of The Korean Dental Society of Anesthesiology
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• v.14 no.2
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• pp.89-94
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• 2014

Local anesthesia known as the safe and essential procedure to control pain in dentistry may cause sensory changes such as paresthesia or altered taste at the affected sites after even successful local anesthesia. Although the prognosis of the nerve injuries after local anesthesia is favorable, it might cause prolonged problems such as dysesthesia. The lingual nerve is a single fascicle at the level of the lingual among 1/3 of patients and more movable during regeneration compared to the inferior alveolar nerve after the injury. As a result, the lingual nerve is more vulnerable and has poorer outcomes. More vigilant clinical considerations are required to the lingual nerve injury after local anesthesia. Generally, more than 80% of cases are spontaneously resolved within 2 weeks after the local anesthesia even without any specific treatment. However, the patient having long lasting abnormal sensations more than 2 weeks needs specialists' care for further assessment. In case of dysesthesia which is a symptom of neuropathic pain, immediate referral to specialists is mandatory. The exact mechanism, how to prevent its occurrence, or specific treatments of the nerve injury related to the local anesthesia have not been elucidated. To prepare clinical or medicolegal problems, many cautious considerations are given to the patients who complain sensory changes after local anesthesia.

• The Journal of the Korean Society for Microbiology
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• v.21 no.1
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• pp.133-144
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• 1986

This study was undertaken to assess the effect of ginseng administration on T lymphocyte induced local xenogenic graft-versus-host(GVM) reactions which were induced with thymocyte, spleen cell and lymph node cell of ICR mice. Mice received daily 10mg of 70% alcohol ginseng extract oral1y for 100days and control mice remained untreated for the same period of time. The cells from donor mice were injected intradermally into the closely shaven abdominal skin of Sprague-Dawley rats for GVH tests. The thymocyte from control(ginseng-untreated) mice showed a negative local GVH reaction, whereas thymocyte from experimental(ginseng-treated) mice showed a positive reaction with the rate of 17.4%. When spleen cells were injected, the incidence of positive local GVH reaction was 66.7% among ginseng-treated mice, as opposed to incidence of 45.5% of positive local GVH reaction among control mice. The incidence of positive local GVH reaction of the lymph node cells when injected into a recipient was 71.4% among ginseng-treated mice as compared with that of 18.9% among control mice. The relationship between spleen cell inoculum and intensity of the local GVH reaction was assessed in ginseng-untreated mice. The intensity of GVH reaction clearly appears to be dose related. In ginseng-treated mice, a minimum of $1{\times}10^7$ spleen cell was required for production of positive local GVH reaction with almost linear relationship up to an inoculum of $5{\times}10^8$ cells. In control mice, however, a minimum of $1{\times}10^8$ spleen cells was required for positive GVH reaction. These results strongly suggest that the ginseng administration augments significantly the local xenogenic GVH reaction which was used to assess T lymphocyte function and immunocompetence of mice and in addition to this, these results appear to support previous suggestions that the local GVH reaction consitutes a qualitative test of the functional activity of T lymphocytes. These results may be the first to induce local GVH reaction, employing rats as recipient and mice as donor. This study was also desingned to investigate some of the effects of ginseng extract on lymphocyte-macrophage interactions. This was accomplished by in vitro quantification of 1) migratory inhibitory factor(MIF) synthetic capacity of splenic lymphocytes in mice previously primed with ginseng 2) MIF responsiveness of mouse peritoneal macrophages or chicken peripheral leucocytes under the presence of ginseng extract 3) migration ability of chicken peripheral leucocytes by direct stimulation of ginseng extract or ginseng saponin and 4) immunosuppressive effects of immunosuppressants such as cyclophosphamide, cyclosporin A or dexamethasone. Mice divided equally into the ginseng and the saline groups, which received intraperitoneally daily 0.2ml of ginseng absolute alcohol-extract(5mg/ml) and same amount of saline for 15 days, respectively. The cellular immune responsiveness of these mice was assayed 15 days after ginseng pretreatment. Splenic lymphocytes of mice treated with ginseng, when stimulated with sensitized specific-antigen such as sheep red blood cells or toxoplasmin, or with polyclonal activator concanavalin A, produced significantly more MIF than those of control saline group. MIF responsiveness of normal mouse macrophages was significantly augmented when assayed under the presence of ginseng extract (1mg/ml). The migratory ability of normal chicken leucocytes in the absence of MIF was significantly decreased by the stimulation of ginseng extract alone. MIF response was significantly decreased by immunosuppressants and this impaired response was not restored by ginseng pretreatment. This study was additionally performed to evaluate the effect of ginseng on the expulsion of adult Trichinella spiralis in mice. ICR mice were infected experimentally by esophageal incubation of 300 T. spiralis infective muscle larvae prepared by acid-pepsin digestion of infected mice. and received oral administration of 70% alcohol ginseng extract(10mg/mouse/day) for the indicated days plus 4 days before infection. At various times after infection, the number of adult T. spiralis worms in small intestines was determined. Interestingly, ginseng-treatment was accompanied by accelerated expulson of T. spiralis. These results led to the conclusion that Panax ginseng caused some enhancing effect on GVH reaction, macrophage migration inhibition reaction and expulsion of T. spiralis. In addition these results suggested that the mechanisms responsible for this enhancement of ginseng may be chiefly or partially due to nonspecific stimulation of cell-mediated immune response.

• Radiation Oncology Journal
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• v.31 no.4
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• pp.191-198
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• 2013

Purpose: To observe long-term clinical outcomes for patients with early-stage breast cancer treated with forward intensity-modulated radiation therapy (IMRT), including local control and clinical toxicities. Materials and Methods: We retrospectively analyzed a total of 214 patients with stage I-II breast cancer who were treated with breast conserving surgery followed by adjuvant breast radiation therapy between 2001 and 2008. All patients were treated using forward IMRT. The whole breast was irradiated to a dose of 50 to 50.4 Gy followed by an 8 to 12 Gy electron boost to the surgical bed. Results: The median age was 46 years (range, 21 to 82 years) and the medial follow-up time was 7.3 years (range, 2.4 to 11.7 years). Stage T1 was 139 (65%) and T2 was 75 (35%), respectively. Ipsilateral breast recurrence was observed in 3 patients. The 5- and 10-year local control rates were 99.1% and 97.8%, respectively. The cosmetic outcome was evaluated according to the Harvard scale and 89.4% of patients were scored as excellent or good. Conclusion: The whole breast radiation therapy as an adjuvant treatment using a forward IMRT technique showed excellent long-term local control as well as favorable outcomes of toxicity and cosmesis.

• Geomechanics and Engineering
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• v.24 no.5
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• pp.479-490
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• 2021

Pre-drainage of groundwater in the roof aquifer by boreholes is the main method for prevention of roof water disaster, and the drop in the water level during the drainage leads to the variation of the local stress in the overlying strata. Based on a multitude of boreholes for groundwater drainage from aquifer above the 1303 mining face of Longyun Coal Mine, theoretical analysis and numerical simulation are used to investigate the local stress variation in the process of borehole drainage. The results show that due to the drop in the water level of the roof aquifer during the drainage, the stress around the borehole gradually evolved. From the center of the borehole to the outside, a stress-relaxed zone, a stress-elevated zone, and a stress-recovered zone are sequentially formed. Along with the expansion of drainage influence, the stress peak in the stress-elevated zone also moves to the outside. When the radius of influence develops to the maximum, the stress peak position no longer moves outward. When the coal mining face advances to the drainage influence range, the abutment pressure in front of the mining face is superimposed with the high local stress around the borehole, which increases the risk of stress concentration. The present study provides a reference for the stress concentration caused by borehole drainage, which can be potentially utilized in the optimal arrangement of drainage boreholes in underground mining.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2002.05a
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• pp.21-25
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• 2002

Activated sludge processes are widely used in biological wastewater treatment processes. The main motivation of this research is to develop an intelligent control strategy for activated sludge process (ASP). ASP is a complex and nonlinear dynamic system because of the characteristic of wastewater, the change in influent rate, weather conditions, and so on. The mathematical model of ASP also includes uncertainties which are ignored or not considered by process engineer or controller designer. The ASP model based on Matlab/Simulink is designed in this paper. The performance of the model is tested by IWA (International Water Association) and COST (European Cooperation in the filed of Scientific and Technical Research) data that include steady-state results during 14 days. In this paper, fuzzy logic control approach is applied to control the DO (dissolved oxygen) concentration. The fuzzy logic controller that includes two inputs and one output can adjust air flowrate. Also, this paper introduces the remote monitoring and control system that is applied for the CSTR (Continuously Stirred Tank Reactor) wastewater treatment system. The CSTR plant has a local control and the remote monitoring system which is contained communication parts which consist of LAN (Local Area Network) network and CDMA (Code Division Multiple Access) wireless module. Remote control and monitoring systems are constructed in the laboratory.

• 제어로봇시스템학회:학술대회논문집
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• 1996.10a
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• pp.133-136
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• 1996

The nozzle dam task is essentially needed to maintain and repair nuclear power plants. For this task, an 8-dof redundant robot is studied with a local path-planning method[l] which is effective to find the optimal joint path in the constrained environment. In this paper, the method[l] is improved practically with the weight matrix and efficient algorithm to find working set. The effectiveness of the proposed method is demonstrated by simulation and animation.

• Korea-Australia Rheology Journal
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• v.15 no.1
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• pp.19-25
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• 2003

Since the microstructure of functional thin films depends on the dispersion characteristics of dense slurry, it is important to control the agglomerative nature of slurries under processing. The present authors have been discussing the model prediction of agglomerative nature and local rate of agglomeration in dense suspensions. The experiments have been peformed under shear flow using the nearly spherical and oblate type graphite particles. In this study, the experiment has been conducted using water and glycerol as dispersion media. Stress control type rheometer was used to measure the slurry rheology. Local agglomeration of graphite particles has been predicted by using Usui's model. The experimental results show that both the shape and slurry processing method affect on the local dispersion condition. The agglomeration formed by oblate type graphite particles seems to be more difficult to break up than that of spherical particles.

• Journal of Institute of Control, Robotics and Systems
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• v.6 no.12
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• pp.1061-1069
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• 2000

In this paper, a new genetic algorithm is proposed for solving multimodal function optimization problems that are not easily solved by conventional genetic algorithm(GA)s. This algorithm finds one of local optima first and another optima at the next iteration. By repeating this process, we can locate all the local solutions instead of one local solution as in conventional GAs. To avoid converging to the same optimum again, we devise a new genetic operator, called a Mendel operator which simulates the Mendels genetic law. The proposed algorithm remembers the optima obtained so far, compels individuals to move away from them, and finds a new optimum.

• Steel and Composite Structures
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• v.24 no.3
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• pp.339-349
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• 2017

In this paper, a conventional refined plastic hinge analysis is improved to account for the effects of local buckling and lateral-torsional buckling. The degradation of flexural strength caused by these effects is implicitly considered using practical LRFD equation. The second-order effect is captured using stability functions to minimize modeling and solution time. An incremental-iterative scheme based on the generalized displacement control method is employed to solve the nonlinear equilibrium equations. A computer program is developed to predict the second-order inelastic behavior of space steel frames. To verify the accuracy and efficiency of the proposed program, the obtained results are compared with the existing results and those generated using the commercial finite element package ABAQUS. It can be concluded that the proposed program proves to be a reliable and effective tool for daily use in engineering design.