• Journal of Oriental Neuropsychiatry
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• v.15 no.2
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• pp.211-219
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• 2004

Panic disorder is a frequent anxiety disorder. Recently many studies raised that the course of panic disorder is the interaction of biological and psychological factor. So we used Oriental Medicine Treatment to control biological factor and Cognitive - Behavioral Therapy to control psychological factor of panic disorder, obtained good results. Practicing Cognitive - Behavioral Therapy, we were able to destroy catastrophic misunderstanding. And then in this case, patient is diagnosed Deficiency of Kidney(腎虛) with Fire from stagnation of Liver(肝鬱化火). So we used herbal medicine and acupuncture according to oriental medical theory and these efforts helped the case of disease.

• Journal of Physiology & Pathology in Korean Medicine
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• v.26 no.6
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• pp.934-939
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• 2012

To investigate and characterize basic patterns of prehypertension. Participants were divided into three groups; ideal blood pressure(n=40), prehypertension(n=62), and stage 1 hypertension groups(n=68) according to the JNC 7 standards. They answered questionnaire asking various symptoms and received clinical examination. Data were collected and analyzed in the focus of three Zheng patterns, cold-heat, deficiency-excess and four major hypertension types. Analysis of variance was used to find differences among groups. In addition, relationship between the cold-heat trends and risk factors of hypertension were analyzed using Pearson's correlation analysis. Three risk factors; age, body mass index (BMI), and fasting blood sugar (FBS) showed intergroup differences. Statistical significances were revealed in the cold-heat pattern and two hypertension subtypes. The cold scores decreased from $4.8{\pm}1.84$ to $3.9{\pm}1.88$ and $3.7{\pm}1.27$ (p=0.022), while the heat increased from $1.9{\pm}1.32$ to $2.8{\pm}1.72$ and $2.8{\pm}1.48$ (p=0.009). Additionally two hypertension subtypes, the excessive liver fire, and the yin-yang deficiency showed significant differences. Cold had negative correlations with blood pressure (both systolic and diastolic), BMI, triglyceride, and FBS. Heat had positive correlations with systolic blood pressure, BMI, triglyceride, and FBS. Prehypertension could be characterized by using the cold-heat patterns. The cold-heat are correlated with Blood pressure, BMI, blood lipids and sugar.

• Herbal Formula Science
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• v.11 no.1
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• pp.45-55
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• 2003

From the study of the symptom, pathology in prescription of Ha-Tong from The Bangyakhapeun. I have reserched 163 prescription. It can be concluded as follows. 1. Prescription about Fecal disease which was the most as 11.66% of the whole, following order Internal disease(6.75%), Uterus Disease(5.52%) Sick-by-Cold Disease(5.52%), Eye Disease(4.91%), Blood Disease(4.91%), Unbalanced humoral status Disease(4.91%), Gynecologic Disease(4.91%). 2. The Fecal Disease divide diarrhea and dysentery; The Internal Disease divides with Sik-sang(食傷) Chu-sang(酒傷), Sik-juck-yu-sang-han(食積類傷寒), Carbonic acid, Vomiting acid; The Uterus Disease divides with Urinnary Disadvantage, Urinary retention, Incontinence; The Sick-by-Cold Disease divides with yang-myung-byung(陽明病), sang-han-goi-jng(傷寒壞證), sang-han-bun-gal(傷寒煩渴), sang-han-sum-ou, sang-han-hyul-jng(傷寒血證), sang-han-ja-ri(傷寒自利), sang-han-bun-jo-jng(傷寒煩燥證). 3. The Diarrhea and Dysentery many used o-ryung-san, hwng-gum-jak-yak-tang(黃芩芍藥湯) hyang-ryun-hwan(香連丸) etc, and The Internal Disease many used pyung-we-san(平胃散) as a basic prescripton. 4. The organ problem use the Sil-yuol(實熱) of the liver, stomach, lung, uterus, small intestine; six natural factors problem used the Sil-jng(實證) of the wind, fire, heat, cold, dampness; And used Unbalanced humoral status, lntrnal hurt, qi and blood, seven extream feeling.

• Journal of Acupuncture Research
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• v.25 no.6
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• pp.67-76
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• 2008

Objectives : The 7-zone-diagnostic system is a diagnostic device to predetermine bodily locations by measuring the energy of body. This study was to investigate the relation between the different patterns of Zone 1, 2, 3 of Factor AA in CP-6000A(VEGA, Germany), 7-zone-diagnostic system and clinical parameters. The purpose of this study was relation Korean traditional medicine and western medicine with the data from 7-zone-diagnostic system and the clinical parameters. Methods : This study was carried out with the data from some clinical parameters. We made three groups according to the Factor AA patterns of CP-6000A. The Factor AA pattern of Group A is that the red bar graph of zone 1, 2, 3 were higher than the normal range and the others were the normal range. The Factor AA pattern of Group B was that the red bar graph of zone 1, 2, 3 was the normal range and the others were the normal range. The Factor AA pattern of Group C was that the red bar graph of zone 1, 2, 3 was lower than the normal range and the others were the normal range. After the data from clinical parameters to correspond with conditions of each group were selected, the data from clinical parameters among each groups analyzed statistically. Results : The values of GOT, GPT, r-GPT, Triglyceride, BUN, Uric acid of group A was higher than group C. Gastroscope of group A and B was higher than group C. Conclusions : It is thought that the red bar graph of zone 1, 2, 3 is higher, the group has the higher energy and the energy has a character of fire(熱). Those patterns have a high risk of hyperlipermia and liver, stomach disease.

• Herbal Formula Science
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• v.19 no.1
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• pp.79-90
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• 2011

Objectives : This study was performed to analysis the composition of herbal formulations about a series of Wolgug-Hwan(WGH, formed by Gukchur-won and Sagung-san) in Dongeuibogam written by Heo Jun. Methods : The series of WGH in Dongeuibogam were selected by 'Prescription Lineage Graph' (http://164.125.206.43/PrescriptionLineageGraph.aspx) established by prof. Lee at Pusan National University. In the analysis of a series of WGH, we used some formulation books including classics. Results : Gaeuldogi-tang(GDT) is formed by WGH, Yeonggangchulgam-tang(YGT), Yugil-san (YIS) and Gungchul-san. Cheongul-san(CUS) is formed by WGH, Ijin-tang(IJT), YGT and Haegeum -hwan(HGH). Sosikcheongul-san(SCS) is formed by CUS and IJT. Jeungmiijin-tang(JIT) is formed by WGH, IJT, Sambaek-tang and Gyullyeonjichul-hwan. Sihoeokgan-tang(SET) is formed by WGH, Sihosogan-san(SSS) and Jigolpi-eum. Wolgukbohwa-hwan(WBH) is formed by WGH, Bohwa-hwan, Mokyangjichul-hwan and Hwangnyeon-tang(HNT). Chimsa-hwan(CSH) is formed by WGH, Injinho-tang(IHT), Yungmisamneung-hwan, Jeungmisamul-tang and Sinseongugi-tang. Conclusions : SCS, CUS, or JIT has been used frequently in case of phlegm-fire. These are formulated by the combination of WGH and IJT with Samseon-san or HGH or Jichul-hwan according to the special symptoms, respectively. SET which is formulated by WGH and SSS has been used in case of stagnation of liver-qi. GDT, WBH or CSH has been used in damp-heat. These are formulated by the combination of WGH with YIS, HNT, or IHT, respectively.

• Korean Journal of Acupuncture
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• v.23 no.3
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• pp.17-27
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• 2006

Objectives : This study is aimed to search for the effective application of the Sa-Am acupuncture(舍岩鍼法) for the treatment of diarrhea. Methods : The classification and the treatment for diarrhea in ${\ll}$Sa-Am-Do-In-Chim-Gu-Yo-Kyul(舍岩道人鍼灸要訣)${\gg}$ was compared with those of ${\ll}$Dong-Eui-Bo-Kham(東醫寶鑑)${\gg}$ and ${\ll}$Chim-Gu-Dae-Sung(鍼灸大成)${\gg}$ Results & Conclusions : In ${\ll}$Dong-Eui-Bo-Kham(東醫寶鑑)${\gg}$, diarrhrea was classified into 20 classes and mainly treated with herbal medicine and additionally with acupuncture treatment. Ashi (nearby) points in lower abdomen and sacral region were often used as well as the points on Spleen meridian(SP) and Stomach meridian(ST) to treat diarrhea in ${\ll}$Chim-Gu-Dae-Sung(鍼灸大成)${\gg}$ According to ${\ll}$Sa-Am-Do-In-Chim-Gu-Yo-Kyul(舍岩道人鍼灸要訣)${\gg}$, Diarrhrea was classified into 6 classes; wet diarrhrea (濡泄; kidney damage), abrupt diarrhrea (暴泄; spleen damage), damp diarrhrea (濕泄; stomach damage), fire diarrhrea (火泄; heart dryness), ki(qi) diarrhrea (氣泄; lung damage) and cold diarrhrea (冷泄; liver damage). Sa-Am acupuncture seems to be applied on the basis of more precise diagnoses of organs and meridians and provide with more fundamental treatments in comparison with classical acupuncture.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.14 no.2
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• pp.110-120
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• 2010

Objective: To relate with significant relationship between symptoms and Five Zhang(五臟)symptoms in Five Woon Constitutions and to characterize Five Woons of Asian women who live at Los Angeles area in U.S.A. Methods: 19 diagnostic questions were given to 286 Asian females subjects who were treated for their symptoms at an Asian medical clinic near Los Angeles in USA. The participants were given their constitutions, one of the Five Woons based on their birthdays. The Cross tabulation analysis was also applied to look for the effectiveness of Five Woons on the symptoms. Results: 1. The cross tabulation analysis showed the significant effectiveness of the Five Woons on the five symptoms including dizziness, hot and cold, lower body edema and face fever(p<0.1). 2. The dizziness and the hot and cold were related with Liver diseases, the lower body edema was related with Kidney diseases and the face fever was related to Heart diseases. Conclusions: This study can explain the relationship between the significant symptoms of Five Woons and Five Zhang(五臟)symptoms with reference which is the book by Yoon, ChoChang who lived 1700 years. Further clinical research is necessary to develop more delicate questionnaires and look for ways of characterizing the Five Woons. The diagnosis and corresponding treatment based on the Five Woons should be further studied in view of the Asian medicine.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.28 no.1
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• pp.80-90
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• 2018

Objectives: This study was performed to propose a domestic occupational exposure limit(OEL) following a health hazard assessment, calculation of a non-carcinogenicity reference concentration worker($RfC_{worker}$) value, and examination of international agencies' exposure limits. It also recommends legal management within the Occupational Safety and Health Act for HCFC-123, which caused an acute hepatotoxicity incident. Methods: An acute hepatotoxicity incident due to the fire extinguishing agent HCFC-123 was investigated. Toxicological hazard and health hazard classifications were examined and a non-carcinogenicity $RfC_{worker}$ value was calculated for HCFC-123. An OEL and the necessity of legal management were recommended as well. Results and Conclusions: An OEL for HCFC-123 of 10 ppm($62.5mg/m^3$), which considered the $RfC_{worker}$ value, 5.56 ppm, produced in dose-response assessment and the exposure level of 19.1-20.9 ppm measured as an eight-hour TWA(time-weighted average) in the incident place, is recommended. HCFC-123 is urged to be included as a chemical requiring legal management in the Occupational Safety and Health Regulations. In addition, it is recommended that a peak exposure of ACGIH be adopted in the Notice of the Ministry of Employment and Labor.

• The Korea Journal of Herbology
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• v.28 no.6
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• pp.25-29
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• 2013

Objectives : The dried root of Sophora flavescens Aiton have been used to treat patient with skin diseases such as eczema in Eastern countries. S. flavescens can clear away heat and dry dampness and purge sthenic-fire from the liver and gallbladder. Recently, anti-allergic effect of S. flavescens has been reported. However, the effect on skin condition of contact dermatitis still remains unknown. Thus, the purpose of this study is to evaluate the efficacy of S. flavescens on contact dermatitis. Methods : In order to investigate the effects of S. flavescens (methanol extract of S. flavescens, MESR) on skin condition, the contact dermatitis was induced in mice skin by using 1-fluoro-2,4-dinitrofluorobenzene (DNFB). As the effective endpoints, skin thickness, skin weight, histopathological change were checked. In addition, effects on skin lesion, body weight and spleen/body weight ratio were also investigated. Results : Topical application of MESR ($500{\mu}g/day$) lowered skin thickness (P < 0.05) and skin weight (P < 0.05), respectively. MESR-treated group showed diminished spongiosis and immune cell infiltration in skin tissues compared to those of non-treated control group. The inhibition of skin lesions was also observed in MESR-treated group. In addition, MESR did not affect body weight gain and spleen/body weight ratio in contrast with those in dexamethasone-treated group. Conclusion : These data suggest that Sophorae Radix could improve skin lesion of contact dermatitis. This indicates the possibility for Sophorae Radix to be used to patients with skin diseases such as contact dermatitis.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.35 no.4
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• pp.209-218
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• 2022

Objective : This study assessed the effect of a combination of Korean medicine on a chronic nipple eczema patient complaining of stress and immunodeficiency due to long-term steroid use. Methods : Herbal medicine, moxibustion and acupuncture were performed for a year. Treatment outcomes were evaluated with DLQI(Dermatology Life Quality Index), EQ-5D-5L(The 5 level of EuroQol 5 Dimensio scale), EQ-VAS(EuroQol-Visual Analog Scale), ADSI(Atopic Dermatitis Severity Index), pruritus NRS(Numeral Rating Scale), pictures and patient's statements. Results : After the treatment, symptoms have been alleviated, the quality of life has increased, and it has been maintained without further nipple eczema for three months. Conclusion : We suggest that Korean medicine is effective for chronic nipple eczema patient.