• 한국항만경제학회지
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• 제26권4호
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• pp.40-62
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• 2010

본 연구는 국제물류주선업체의 부서 간 역학관계가 시장지향성에 어떠한 영향을 미치는지, 그리고 시장지향성이 관계몰입을 통해 고객성과에 미치는 영향에 대해 규명하여 국제물류주선업체의 경쟁력을 향상시키고자 실시하였다. 연구결과 부서 간 연계를 통해 부서 간 갈등수준이 낮아져야 시장지향성이 높아진다는 것을 알 수 있었다. 하지만 시장지향성이 고객성과에 미치는 영향에 대해서는 유의한 영향력을 확인할 수 없었으며, 시장지향성은 관계몰입이라는 매개변수를 통해 고객성과에 유의한 영향을 미친다는 점이 밝혀졌다. 현재 우리나라의 국제물류주선업의 시장은 매우 경쟁적이며, 경쟁전략의 대부분이 비용전략이며, 비용전략은 다른 경쟁기업이 고객에게 제공하는 비용에 따라 수시로 바뀌는 실정임을 비추어 볼 때, 국제물류주선업체들은 출혈경쟁을 지양하고, 고객기업과의 신뢰형성과 장기적인 관계유지를 위해 노력을 기울여야 경쟁력이 강화될 것으로 보인다.

• 한국정보시스템학회지:정보시스템연구
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• 제18권4호
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• pp.19-40
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• 2009

승자독식(Winner Takes All)이라는 글로벌 경쟁원리로 인해 세계 주요 국가들 사이에 R&D 경쟁이 갈수록 치열해지고 있다. 이에 우리나라에서도 R&D 지원 확대 및 다양한 정책기획 활동 등이 전개되었다. 이러한 노력에도 불구하구 국가 차원에서 기획 및 정책조정이 효과적으로 추진되지 못하고 있으며, 국가연구개발사업 차원에서는 "기획의 양척 과다와 질적 부실"이라는 비판이 제기되고 있다. 반면에 기술 융복합화의 가속화 등 R&D 환경의 불확실성은 더욱 높아졌으며 국가연구개발사업의 규모 증가와 함께 연구기획의 복잡성은 더욱 더 높아졌다. 최근에는 국가 차원의 비전수립과 중장기 정책기획에 기초하여 사업기획과 과제기획을 연계 수행하는 등 기획을 통해 과제를 도출하는 하향식 접근이 강조되면서 기획의 중요성은 더욱 커졌다. 최근 연구기획의 새로운 기법으로서 정보분석 방법론(Information Analysis Method)이 대두되고 있다. 국가연구개발사업의 효율적 기획을 위하여 기존 기술기획 위원회(Peer Review) 방식 외에 정보분석 방법론을 통한 보완이 필요하다. 본고의 목적 크게 두 가지로 설명할 수 있다. 첫째, 현재 진행되고 있는 연구기획 및 연구기획 방법론으로 기장 많이 활용되고 있는 전문가 위원회의 한계를 제시하였다. 둘째, 최근 대두되고 있는 정보분석 방법론과 정보분석 시스템 구축, 그리고 이를 활용한 10대 기술(반도체, 디스플레이, 디지털 망원전파, 이동통신, BcN, 차세대 컴퓨팅, SW솔류션, 디지털콘텐츠, 임베디드 SW, 지식정보보안)에 대한 유망기술 발굴 실증분석을 실시하였다.

• 과학기술학연구
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• 제14권2호
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• pp.223-249
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• 2014

과학이 문학에 끼친 영향은 비교적 친숙한 주제로서 이에 관해 많은 연구가 이루어져 왔으며, 그 가운데에서 다윈 진화론이 문학에 끼친 영향은 19세기 역사와 두 문화 연구자들한테 흥미로운 주제가 되어 왔다. 이 글은 기존의 주요한 연구 흐름을 정리하며 19세기 영국과 근대 한국의 계몽문학에 나타난 다윈 진화론의 영향을, 몇 가지 주요 특징을 중심으로 개관한다. 또한 진화론이 문학뿐 아니라 문학을 바라보는 관점까지 바꾸어놓았다는 점에서, 문학 행위 자체를 마음 진화의 소산으로 바라보는 진화심리학의 문학비평 관점을 함께 살핀다. 특히 이 글은 진화론의 영향과 연관된 시와 소설의 변화가 사회와 개인이 처한 상황과 종교적, 사회적 믿음에 따라 다양한 모습으로 나타났다는 점, 그리고 자연, 인간, 진화의 재발견을 통한 서사, 은유, 마음의 재인식이 문학 격동의 바탕을 이루고 있었다는 점을 보여주고자 한다.

• 한방안이비인후피부과학회지
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• 제13권1호
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• pp.157-184
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• 2000

Bromidrosis is a disease which is also called huchou[호격] in the oriental medicine. This disease produces an odor and a small amount of sweat from the axillary area. Prognosis of the disease could possibly get better with age. This can be explained by the fact that its symptoms begin usually when a person reaches puberty and as the person gets old, the symptoms reduce or disappear even when specific treatments are not applied. Although the disease is not lethal, many patients have difficulties in leading a normal and comfortable life, physically and psychologically with this in mind and some osbservations gained from the literature studies on the causes,symptoms, and treatments, I embarked on a study aimed at finding out the therapies. My study on the literature has produced the following results ; 1. In the oriental medicine, hu-chou[호격] means the characteric smell or odor produced from the fox. 2. The literature studies point out two causes in the oriental medicine. One is natural. The other is acquired. Acquired cases have the following causes: shi-re-nei-yun[濕熱內蘊]. xie-뱌-bu-huo[血氣不和], gan-qi-yu-jie[肝氣鬱結]. 3 There are two therapies in the oriental medicine. One is internal and the other external. out of the two, external therapies were mainly used according to the literature studies that I have consulted. 4. According to my study, the most frequently used herbal medicine was Alunitum(明 礬)(45 times), followed by Minium(密陀僧)(39 times) and Moschus(?香)(21 times respectively). 5. My study also found that bian-zheng[辨證] was not .rarely listed on old literatures. Therefore, old literatures did not clearly show how to root out the disease. They only taught now to alleviate the symptoms and remove the characteric odor.

• 사상체질의학회지
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• 제27권1호
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• pp.82-109
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• 2015

Objectives This research was proposed to present Clinical Practice Guideline (CPG) for Prevention of Sasangin disease pattern of Sasang Constitutional Medicine (SCM) and diseases closely related with Sasang constitution. Each CPG was developed by the national-wide experts committee consisting of SCM professors. Methods At first, we searched the literatures related to SCM such as "Dongeuisusebowon", Textbook of SCM and Clinical Guidebook of SCM. Also we searched the articles related to the studies about risk factors for Sasangin disease pattern of both at home and abroad. Finally, we selected leading risk factors of Sasangin disease pattern and developed CPG for prevention of Sasangin disease pattern of SCM. And then, we searched the literatures related SCM such as "Dongeuisusebowon" and the articles on the correlation between disease and Sasang constitution using case-control studies, observational studies or cross sectional studies of both at home and abroad. Next, we selected diseases closely related with Sasang constitution on the basis of articles including prevalence rate and odds ratio between disease and Sasang constitution and finally developed CPG for these diseases. Results and Conclusions We categorized risk factors of Sasang disease pattern into 2 types: non-modifiable and potentially modifiable. 3 items (age, sex and genetic factors) were classified as non-modifiable risk factors of Sasang disease pattern. 6 items (original symptom, stress, diet and nutrition, physical activity, alcohol and drug misuse) were classified as less well-documented or potentially modifiable risk factors of Sasangin disease pattern. We found out Sasang constitution is more likely to develop some diseases. It was proven that Sasang constitution increase the risk of hypertension, diabetes mellitus, metabolic syndrome, stroke, nonalcoholic fatty liver and obstructive sleep apnea. And there is high probability of Sasang constitution being potential risk factor for obesity, hyperlipidemia, allergy and cancer. Also, we found out Taeeumin is independent risk factor for hypertension, diabetes mellitus, metabolic syndrome, stroke, nonalcoholic fatty liver and obstructive sleep apnea. Therefore we recommend that Taeeumin need to prevent these disease by regular checkups and aggressive management.

• Korean Journal of Acupuncture
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• 제33권2호
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• pp.47-57
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• 2016

Objectives : Six command points are individual points that have strong and broad effects on their related part of the body, but there is a controversy about which acupoints are should be included in the six command points. This research was reviewed which acupoints are suitable for the construction of the six command points. Methods : We searched acupoints mentioned six command points in literatures, then investigated the effects of the acupoints to identify that they can be included in the six command points. And we deliberated which acupoints are suitable for the six command points. Results : Acupoints mentioned the six command points are LU7, LI4, ST36, BL40, PC6, TE6, GV26, ouch point, GB34 and SP6. Among the acupoints, LU7, LI4, ST36, BL40 and PC6 was included in the six command points in all of searched literatures. And GV26, ouch point, GB34 and SP6 were excluded because GV26 and ouch point were not fit the definition of the six command points, ST36 can be an alternative to SP6 based on their effects, and GB34 has a similar but little effect compared to TE6. Conclusions : Based on the definition of six command points and the effect of the acupoints, we suggest that the six command points should be composed of LU7, LI4, ST36, BL40, PC6 and TE6.

• Journal of Genetic Medicine
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• 제13권2호
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• pp.59-64
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• 2016

Gaucher disease type 1 (GD1) is an inherited lysosomal storage disorder caused by deficiency of acid ${\beta}$-glucosidase. The diminished enzyme activity leads to the accumulation of substrates and results in multi-systemic manifestations including hepatosplenomegaly, anemia, thrombocytopenia, and bone diseases. Enzyme replacement therapy (ERT) by infusion of recombinant protein has been the standard treatment for over 20 years. Despite the successful long-term treatment with ERT, several unmet needs remain in the treatment of GD1 such as severe pulmonary and skeletal manifestations. Substrate reduction therapy (SRT) reduces the accumulation of substrates by inhibiting their biosynthesis. Eliglustat, a new oral SRT, was approved in United States and Europe as a first-line therapy for treating adult patients with GD1 who have compatible CYP2D6 metabolism phenotypes. Although eliglustat is not yet available in Korea, introduction and summary of this new treatment modality are provided in this paper by review of literatures. Despite the fact that there are only limited studies to draw resolute conclusions, the current data demonstrated that eliglustat is not inferior to ERT in terms of its clinical efficacy. The approval of eligustat enables eligible adult GD1 patients to have the option of oral therapy although it still needs further studies on long-term outcomes. The individual patient should be assessed carefully for the choice of treatment modality when eliglustat becomes available in Korea. Furthermore, the clinical guidelines for Korean patients with GD1 regarding the use of eliglustat needs to be developed in near future.

• 대한약침학회지
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• 제4권2호
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• pp.35-47
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• 2001

Objectives : Through the literatures on the effets of Bufonis Venenum, we are finding out the clinical possibility and revealing the more effective to intractable diseases. Methods : We investigated the literatures of Oriental Medicine and experimental reports about Bufonis Venenum. Results : 1. Bufonis Venenum is made of bufonidae bufo bufo gargarizans cantor or bufo melanostictus schneider of white serum which secreted from parotid gland or dermato gland, and it is dried for using. 2. In oriental medicine, Bufonis Venenum has been mainly used on the tumors, cacanthrax and dermatic disease, and then it has been clinically used on infantile athrepsia, tetanus, sore throat, toothache, and so on. 3. The pharmacological effects of Bufonis Venenum are cardiotonic, respiration stimulation, depressor or vasopressor, topical anesthcsia, hallucination, striped muscle stimulation, antiasthmatic, antibacterial, antiinflammatory, anticancer, diuretic, immuno effects, etc. 4. Bufonis Venenum is largely divided in ether binding steroid compound, hydroxyl steroid compound, carboxyl or aldehyde steroid compound, indole compound, and adrenaline, cholesterole, etc. 5. Symptoms of Bufonis Venenum poisoning in digestive system are vommitig, abdominal pain, diarrhea, dehydration, in circulatory system are palpitation, shock, bradycardia, in nervous system are vertigo, somnolentia, muscle-tendon reflex weakness, and critical conditions to tissue necrosis and heart attack. 6. Ways to treat Bufonis Venenum poisoning include gastric irrigation with $0.2~0.5\%$ potassium permanganate fluid and atropine $0.5{\sim}1.0mg$ subcutaneous injection. From the chinese book of Bon Cho Gang Moke(本草綱目), if white serum of Bufonis Venenum enter the eyes, it happens the edema and pain. And then washed the eyes by juice of Lithospermi Radix(紫草) that the edema is removed. Conclusions and Discussion : The results from above literary studies show that prescriptions and Aqua-acupuncture of Bufonis Venenum could be clinically used to sedative, anticonvulsant, antibacterial, antiinflammatory, anticancer and topical ataralgesia. However it is expected that pharmacological and side effects of Bufonis Venenum are further studied.

• Journal of Chest Surgery
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• 제39권4호
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• pp.340-342
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• 2006

원발성 흉골 골수염은 드문 질환이다. 특히 소아에서 발생한 경우는 매우 드물어 영어로 보고된 문헌에 11예가 보고되었다. 원발성 흉골 골수염은 영양실조, 면역 저하, 흉부 둔상, 정맥을 통한 약물 주사, 낫 세포빈혈증 등의 환자에서 주로 발생하며, 배농 및 항생제 투여로 치료한다. 저자들은 기저질환이 없는 16세 남아에서 발생한 원발성 흉골 골수염 1예를 문헌 고찰과 함께 보고하는 바이다.

• 생약학회지
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• 제5권3호
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• pp.147-154
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• 1974

Some crude drugs in ancient literatures have been used as traditional therapeutic agent of leucorrhea mainly caused by Trichomonas vaginalis and Candida albicans. Sixty six kinds of crude drugs in ancient literatures and ten constituents were selected as sample drugs. Trichomycin standard was tested to compare with the above drugs. To determine the anti-fungal effect of these drugs on Candida albicans Yu 1200, a test organism, screening test was conducted. Antifungal activities of crude drug water extracts were observed by means of two test methods : firstly through the agar slant method and secondly the counting chamber method which was used for acknowledged drug agents upon the result of the agar slant method. And in order to improve the fungicidal effect, the organisms were stained with 0.02% methylene blue solution. The results of the above test indicated that Fritillariae Rhizoma has antifungal action in the concentration of 310mcg/ml, Coptidis Rhizoma in 620mcg/ml, Meliae Cortex, Scutellariae Radix both in 5,000mcg/ml. Baicalin, catechol among the pure isolated constituents inhibited in the range of 50mcg/ml. This score was based on 50% inhibition in comparison with amounts of control organisms. Rhei Rhizoma, Mori Radicis Cortex, Linderae Radix, and Amomi globosi Fructus showed the antifungal effect moderately in 5,000mcg/ml, and baicalein and pectolinarin in 50mcg/ml in the limit of between 35% and 50% antifungal activity. Staining with 0.02% methylene blue showed that any of the crude drug extracts was unable to stain the cells, but trichomycin in 0.86unit/ml able to stain 12% of the cells. This result means that crude drugs probably do not have fungicidal but fungistatic action.