• Title/Summary/Keyword: literature evidence

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Recent Developments in the Use of Intralesional Injections Keloid Treatment

  • Perdanasari, Aurelia Trisliana;Lazzeri, Davide;Su, Weijie;Xi, Wenjing;Zheng, Zhang;Ke, Li;Min, Peiru;Feng, Shaoqing;Zhang, Yixin;Persichetti, Paolo
    • Archives of Plastic Surgery
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    • v.41 no.6
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    • pp.620-629
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    • 2014
  • Keloid scars are often considered aesthetically unattractive and frustrating problems that occur following injuries. They cause functional and cosmetic deformities, displeasure, itching, pain, and psychological stress and possibly affect joint movement. The combination of these factors ultimately results in a compromised quality of life and diminished functional performance. Various methods have been implemented to improve keloid scars using both surgical and non-surgical approaches. However, it has proven to be a challenge to identify a universal treatment that can deliver optimal results for all types of scars. Through a PubMed search, we explored most of the literature that is available about the intralesional injection treatment of hypertrophic scars and keloids and highlights both current (corticosteroid, 5-fluorouracil, bleomycin, interferon, cryotherapy and verapamil) and future treatments (interleukin-10 and botulinum toxin type A). The reference lists of retrieved articles were also analysed. Information was gathered about the mechanism of each injection treatment, its benefits and associated adverse reactions, and possible strategies to address adverse reactions to provide reliable guidelines for determining the optimal treatment for particular types of keloid scars. This article will benefit practitioners by outlining evidence-based treatment strategies using intralesional injections for patients with hypertrophic scars and keloids.

Meta-Analysis on the Effect of Therapeutic Horseback Riding on Children with Developmental Disabilities and Neural Patients

  • Noh, Hyunju;Kim, Jiyoung;Park, Jiwon
    • The Journal of Korean Physical Therapy
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    • v.32 no.5
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    • pp.312-318
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    • 2020
  • Purpose: This study aimed to investigate the evidence that therapeutic horseback riding can improve balance, muscle, ADL, equivalenc, GMFM, gait, emotion with developmental disabilities and neural patients. Methods: To conduct meta-analysis, the search focused on studies that employed therapeutic horseback riding for developmental disabilities and neural patients for which eight databases (KIS, RISS, DBpia, National Assembly Library, Pubmed, Embase, Google scholar and Cochrane Library) were used to extract literature published from 2002 to September 2019. The data were analyzed the RevMan 3.5.3 program. Results: As a result of meta-analysis, therapeutic horseback riding total effect size is 0.552 for children with developmental disabilities and neural patients. And effect size result of according to assessment type variable first, balance effect size is 0.594. Second, muscle activities effect size is 0.425. Third, ADL effect size is 0.430. Fourth, equivalance effect size is 0.640. Fifth, GMFM effect size is 0.482. Sixth, gait effect size is 0.400 and seventh emotion effect size is 0.876. Conclusion: These findings is horseback riding is effective The effect size by outcome was observed to be the effective for children with developmental disabilities and neural patients. and also the horseback riding provided the positive effects of balance, muscle activities, ADL, equivalance, GMFM, gait, emotion for children with developmental disabilities and neural patients. It is hoped that this study will contribute to the development of effective treatments for children with developmental disabilities and neural patients therapeutic horseback riding and the development of study.

Complicated Wound Infection Following Transvenous Endocardial Pacemaker (경정맥(經靜脈) 내적(內的) Pacemaker 이식후(移植後) 발생(發生)한 복잡한 감염합병증(感染合?症)의 1치험례(治驗例))

  • Lee, D.Y.;Yoon, Y.J.;Cho, B.K.;Hong, S.N.
    • Journal of Chest Surgery
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    • v.9 no.2
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    • pp.265-270
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    • 1976
  • Implantation of a permanent pacemaker is a widely accepted procedure for the patient with complete heart block.As a result of these device, the prognosis for patients with Adams-Stokes syndrome caused by complete A-V block and other cardiac arrhythmia have become much more optimistic. Permanent pacemaker implantation by means of a transvenous approach has made the operative risk much less and the procedure simpler. However, a number of complications have been reported in the literature regarding transvenous endocardial pacemaker implantation during the last a decade. The patient presented in this paper is a 26-year old girl who was implanted with a permanent pacemaker at 14 years of age because of a congenital A-V block. Following first exchange of pulse generator, the electrode (lead) was fractured, so that by the pulse generator, a change to the transvenous technique of implantation was made, After this, there were episodes of recurrent wound infection on three occasions, even though the site of pulse generator implantation was exchanged to the contralateral side of chest wall, massive doses of antibiotics were administered and sensitivity tests for coagulase positive staphylococcal infection were performed. Though there was no definite evidence of blood stream infection by blood culture, we decided not to use the transvenous technique and not to implant the pulse generator in the chest wall because the venous system and the entire anterior chest wall appeared to be diseased or contaminated by virulent pyogenic organisms. Finally this intractable systemic and local wound infection was successfully controlled by myocardial lead implantation via a subxiphoid approach and implantation of the pulse generator far down in the abdominal wall. The causes and routes of recurrent wound infection and possible blood born infection in this particular patient are still obscure. We strongly believe that myocardial pacemaker implantation is much safer than transvenous endocardial pacemaker implantation & myocardial pacemaker implantation is a definite method for controlling such an intractable wound infection. following transvenous pacemaker implantation.

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Usages of Aconite (부자(附子)의 활용(活用)에 대한 고찰(考察))

  • Lu, Huan-Yu;Kang, Mi-Jeong;Lee, Ji-Won;Yoo, Jung-Hee;Lee, Jun-Hee;Koh, Byung-Hee;Lee, Eui-Ju
    • Journal of Sasang Constitutional Medicine
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    • v.22 no.3
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    • pp.51-58
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    • 2010
  • 1. Objectives: After arranging the contents of the usages of Aconite mentioned in the literature - "Dongmu", a power trend me to further study the details of the usages of Aconite. 2 Methods: This study mainly refers to; "Dongmu-YuGo(東武遺稿)"(DYG), "Donguisusebowon-SaSangchobongyun(東醫壽世保元四象草本卷)"(DSS), "Donguisusebowon-GabObon(東醫壽世保元甲午本)"(DGO), "Donguisusebowon-ShinChukbon(東醫壽世保元辛丑本)"(DSC), and the research was written in order to find out the physiology and pathology of Soeumin in SCM. 3 Results and Conclusions 1) Taking aconite in a scale of 3 to 15 gram as common dosage, especially, when a person was critically ill, the dosage of 45 gram was used. Different dosages of aconite were chosen in accordance with some other different conditions, such as the purpose of reducing fever or mid-energizer warming, urinary volume, presence or absence of edema, stages of growth of diseases. In addition, we found a remedy using Remedy Single head garlic(獨頭蒜) instead of aconite. 2) Adverse toxic effects of aconite can be serious, it is dangerous to patients who are administered with aconite in massive amounts or take it in different concocting methods, therefore, further evidence about the laboratory experiments studied in animals and clinical dataare needed to confirm the scope for more widespread and accurate usages of Aconite.

Sympathetic Nerve Function to Electrical Response of Ryodoraku Point and Disarrangement of its Meridian Location on the Anatomical Viscera Exclude the Association between Ryodoraku Theory and Meridian Principle (양도점의 전기적 반응에 대한 교감신경작용과 경락 배열과 실질장기의 불일치는 양도락의 경락 관련성을 배제한다.(위 운동장애형 기능성 소화불량증 환자의 양도점 H4,5,6의 반응을 중심으로))

  • Yoon, Sang-Hyub
    • The Journal of Internal Korean Medicine
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    • v.32 no.2
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    • pp.259-277
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    • 2011
  • Objectives : The purpose of this study was to investigate two subjects: the diagnostic value of bilateral lowering of electrical activity at point H4,5,6 of Ryodoraku and the mechanism for Ryodoraku phenomena. Methods : Electrical activities of Ryodoraku test and electrogastrography recorded simultaneously and monitored continuously from 16 cases of functional dyspeptic patients were collected and their variations were grouped by the topics of discussion which were peculiarity, stability, lagging, alterability, and anomaly. Ryodoraku recordings obtained from 6 patients with different gastrointestinal diseases and 1 normal healthy person were used as control. The results are discussed with Nakatani's suggestion, theory of sympathetic nerve and Meridian Principle, respectively. Finely, coincidence of stomach arrangement between anatomy and meridian system in Ryodoraku was also evaluated. Results : Time-course variation showed a regular relationship between the typical pattern of Ryodoraku at point H4,5,6 and gastric myoelectrical activity. However, an irregular relationship and atypical pattern of Ryodoraku occasionally appeared. A literature search suggested that electrical response at the Ryodoraku point H4,5,6 may be dependent on an afferent sympathetic spinal reflex transmitted from the stomach. However, there was no evidence for making clear whether bilateral lowering of electrical activity at this point was induced by hypofunction of local sympathetic nerve in the skin itself or of signals transmitted from the gastric sympathetic nerve or not. The coincidence of 19% could not provide a visceral arrangement of the stomach between anatomy and meridian systems. Conclusions : Bilateral lowering of electrical activity at Ryodoraku point H4,5,6 has value as a diagnostic index for gastric dysmotility of functional dyspepsia. This phenomenon is associated with spinal reflex transmitted from the afferent sympathetic nerve in the stomach but not that of meridian function.

Analysis of Nursing Intervention Studies on Patients with Breast Cancer in Korea (유방암환자 대상 국내 간호중재 연구 분석)

  • Choi, Kyung-Sook;Kim, Mi-Sook;Lee, In-Ja;Han, Sang-Young;Park, Jung-Ae;Lee, Joo-Hyun
    • Asian Oncology Nursing
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    • v.11 no.1
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    • pp.74-82
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    • 2011
  • Purpose: This study was performed to systematically review the recently published nursing intervention studies. Methods: The literature was identified through the Korean Education and Research Information Service (KERIS), the Korean Information Service System (KISS), and National Assembly Library websites. Key words such as breast cancer, nursing, and intervention were used. The factors analyzed are as follows: 1) the characteristics of studies and study populations, 2) the classification of interventions, 3) outcome indicators and their effects, and 4) effective interventions. Results: Thirty two studies were included. Seventeen studies used a single intervention such as aerobic dance, TaiChi, foot massage, aromatherapy, or a stress-reduction method. Fifteen studies used combined interventions, including education, exercise, counseling, support, yoga or meditation. The data on 47 outcome indicators and their effects were segregated into psycho/spiritual outcomes, stress coping, physical outcomes, cardiorespiratory function, symptom management, arm and shoulder functions, fatigue, and quality of life. Some interventions had positive effects on stress, fatigue, and functions of shoulder. Conclusion: Various interventions are available for breast cancer patients, and some have had positive effects. However, more studies are required to develop evidence-based practice guidelines for nursing interventions.

A Case of Primary Esophageal Malignant Lymphoma -A Case Report- (식도 림프종 -1례 보고-)

  • Her, Keun;Park, Young-Woo;Kim, Hyun-jo;Heo, Jae-Hak;Jeong, Youn-Seop;Youm, Wook;Jin, So-Young
    • Journal of Chest Surgery
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    • v.35 no.4
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    • pp.318-321
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    • 2002
  • The esophageal lymphoma is a very rare feature among gastrointestinal lymphoma, and there was no surgical report in Korea. A 62-year-old male patient with submucosal tumor detected on routine esophagoscopy had resection of tumor including the esophageal mucosa, which was confirmed as esophageal lymphoma. As the severe leakage was detected on esophagogram on post-op 7th day, esophagectomy and esophagogastrostomy was followed. Though adjuvant chemotherapy was not performed, there were no evidence of recurrence for 1 year follow up. We experienced a patient with esophageal lymphoma and reported with brief review of literature

Sustaining Low-Carbon Emission Development: An Energy Efficient Transportation Plan for CPEC

  • Zubedi, Asma;Jianqiu, Zeng;Arain, Qasim Ali;Memon, Imran;Khan, Sehrish;Khan, Muhammad Saad;Zhang, Ying
    • Journal of Information Processing Systems
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    • v.14 no.2
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    • pp.322-345
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    • 2018
  • Climate change has become a major challenge for sustainable development of human society. This study is an attempt to analyze existing literature to identify economic indicators that hamper the process of global warming. This paper includes case studies based on various countries to examine the nexus for environment and its relationship with Foreign Direct Investment, transportation, economic growth and energy consumption. Furthermore, the observations are analyzed from the perspective of China-Pakistan Economic Corridor (CPEC) and probable impact on carbon emission of Pakistan. A major portion of CPEC investment is allocated for transportation. However, it is evident that transportation sector is substantial emitter of carbon dioxide (CO2) gas. Unfortunately, there is no empirical work on the subject of CPEC and carbon emission for vehicular transportation. This paper infers that empirical results from various other countries are ambiguous and inconclusive. Moreover, the evidence for the pollution haven hypothesis and the halo effect hypothesis is limited in general and inapplicable for CPEC in particular. The major contribution of this study is the proposal of an energy efficient transportation model for reducing CO2 emission. In the end, the paper suggests strategies to climate researchers and policymakers for adaptation and mitigation of greenhouse gases (GHG).

A Review Study of Researches on Three Decoctions Including Fructus trichocanthis and Bulbus allii macrostemi in Geum-Gwe-Yo-Ryak (<금궤요략(金匱要略)> 내(內) 과루(瓜蔞)와 해백(薤白)이 포함된 3방제(方劑)에 대한 연구동향(硏究動向) 고찰(考察))

  • Oh, Won-jong;Park, Chung A;Byun, Sung Hui;Kim, Sang Chan
    • Herbal Formula Science
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    • v.28 no.4
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    • pp.407-428
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    • 2020
  • Objectives : The purpose of this study is to review the effect of Guaruhaebaekbaekju-tang (GHBJ), Guaruhaebaekbanha-tang (GHBH) and Jisilhaebaekgyeji-tang (JHGJ) by summarizing Korean and English articles. Methods : The study was based on 23 papers published since 1995. Papers were searched on seven domestic electronic databases including Koreantk, NDSL, RISS, KISS, OASIS, Koreamed and Library of Korea University and three international electronic databases including PUBMED, Embase and Science Direct. Results : 1. 23 research papers were collected, including 13 in vitro studies, 6 in vivo studies, 2 case reports and 2 literature studies. 2. GHBJ, GHBH and JHGJ showed significant myocardial protective and anti-hyperlipidemic and anti-inflammatory effects. In addition, researches on anti-oxidant, thrombosis, and atherosclerosis have been conducted in various ways. 3. It can be confirmed that these studies are related to Chest and back pain (胸背痛), Insomnia by chest paralysis (胸痺不得臥), Stabbing pain that radiates from chest to back (心痛徹背), Chest numbness (心中痞), Obstruction of qi in the chest (留氣結在胸), Fullness sensation in chest (胸滿) among the terms. Conclusion : Through these results, close association was found between classic description and modern research about GHBJ, GHBH and JHGJ, and the possibility of providing objective evidence was confirmed. To improve the quality of the study, large scale studies will be required to evaluate the authority of GHBJ, GHBH and JHGJ.

Solitary Plasmacytoma of the Rib - A case report - (늑골에 발생한 고립성 형질세포종 - 1예 보고 -)

  • Lee, Young-Ok;Ryu, Kyoung-Min;Cho, Suk-Ki;Lee, Eung-Bae
    • Journal of Chest Surgery
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    • v.42 no.2
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    • pp.268-271
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    • 2009
  • Solitary plasmacytoma of bone is a rare disease that accounts for only about $3{\sim}5%$ of all plasma cell tumors. Especially, no case of solitary plasmacytoma of a rib origin has been described in the Korean literature. A 54 year old Korean man was referred to our hospital for further evaluation of a lung mass that had been detected on a screening chest radiograph. A tumor with a left 6th rib origin was revealed by the computed tomography(CT) and positive emission tomography (PET-CT); therefore, surgical resection was performed. The histopathological findings of the tumor revealed plasmacytoma of a rib origin. The postoperative screening test revealed no evidence of multiple myeloma. Postoperative radiation therapy was not performed, and no new lesion has been noted during the 2 years of follow up.