Herbal Formula Science (대한한의학방제학회지)

The Korean Medicine Society for the Herbal Formula Study (대한한의학방제학회)
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A Review Study of Researches on Three Decoctions Including Fructus trichocanthis and Bulbus allii macrostemi in Geum-Gwe-Yo-Ryak

<금궤요략(金匱要略)> 내(內) 과루(瓜蔞)와 해백(薤白)이 포함된 3방제(方劑)에 대한 연구동향(硏究動向) 고찰(考察)

  • Received : 2020.10.19
  • Accepted : 2020.11.24
  • Published : 2020.11.30
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Abstract

Objectives : The purpose of this study is to review the effect of Guaruhaebaekbaekju-tang (GHBJ), Guaruhaebaekbanha-tang (GHBH) and Jisilhaebaekgyeji-tang (JHGJ) by summarizing Korean and English articles. Methods : The study was based on 23 papers published since 1995. Papers were searched on seven domestic electronic databases including Koreantk, NDSL, RISS, KISS, OASIS, Koreamed and Library of Korea University and three international electronic databases including PUBMED, Embase and Science Direct. Results : 1. 23 research papers were collected, including 13 in vitro studies, 6 in vivo studies, 2 case reports and 2 literature studies. 2. GHBJ, GHBH and JHGJ showed significant myocardial protective and anti-hyperlipidemic and anti-inflammatory effects. In addition, researches on anti-oxidant, thrombosis, and atherosclerosis have been conducted in various ways. 3. It can be confirmed that these studies are related to Chest and back pain (胸背痛), Insomnia by chest paralysis (胸痺不得臥), Stabbing pain that radiates from chest to back (心痛徹背), Chest numbness (心中痞), Obstruction of qi in the chest (留氣結在胸), Fullness sensation in chest (胸滿) among the terms. Conclusion : Through these results, close association was found between classic description and modern research about GHBJ, GHBH and JHGJ, and the possibility of providing objective evidence was confirmed. To improve the quality of the study, large scale studies will be required to evaluate the authority of GHBJ, GHBH and JHGJ.

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References

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