• Title/Summary/Keyword: literature evidence

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Efficacy and Safety of Gabapentin in the Treatment of Chronic Cough: A Systematic Review

  • Shi, Guanglin;Shen, Qin;Zhang, Caixin;Ma, Jun;Mohammed, Anaz;Zhao, Huan
    • Tuberculosis and Respiratory Diseases
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    • v.81 no.3
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    • pp.167-174
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    • 2018
  • Despite recent clinical guidelines, the optimal therapeutic strategy for the management of refractory chronic cough is still a challenge. The present systematic review was designed to assess the evidence for efficacy and safety of gabapentin in the treatment of chronic cough. A systematic search of PubMed, Embase, Cochrane Library databases, and publications cited in bibliographies was performed. Articles were searched by two reviewers with a priori criteria for study selection. Seven relevant articles were identified, including two randomized controlled trials, one prospective case-series designed with consecutive patients, one retrospective case series of consecutive patients, one retrospective case series with unknown consecutive status, and two case reports comprising six and two patients, respectively. Improvements were detected in cough-specific quality of life (Leicester Cough Questionnaire score) and cough severity (visual analogue scale score) following gabapentin treatment in randomized controlled trials. The results of prospective case-series showed that the rate of overall improvement of cough and sensory neuropathy with gabapentin was 68%. Gabapentin treatment of patients with chronic cough showed superior efficacy and a good safety record compared with placebo or standard medications. Additional randomized and controlled trials are needed.

Importance of Oral Environment for Environmental Hormones Interaction with Human Body for Future Research

  • Lee, Seong-Won;Jeon, Jae-Yoon;Oh, Byung-Cheol;Choi, Jong-Won;Ro, Seong-Su;Park, Chang-Joo;Hwang, Kyung-Gyun
    • Journal of Korean Dental Science
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    • v.10 no.1
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    • pp.1-9
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    • 2017
  • There is increasing evidence that the environmental hormones may adversely affect the human body. The human reproductive system misrecognizes some of these endocrine disruptors with consequences to reproductive cell differentiation. Therefore, studies on the safety of these substances have been widely carried out to develop the science to create effective legislation to limit or prevent their use or require the development of inert, alternative substances. A few studies have reported that the oral cavity is the pathway for absorption of these substances released from plastic products or environmental hormone substances. This review suggests that the oral environment is vulnerable to exposure to environmental hormones and introduces supporting literature.

Development of Education Program for Family of Patients with Brain Injury (무의식 뇌손상 환자의 가족을 위한 교육자료 개발)

  • Yoo, Yang-Sook;Yun, Sun Hee;Cho, Ok-Hee
    • Journal of Home Health Care Nursing
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    • v.19 no.2
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    • pp.127-138
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    • 2012
  • Purpose: This study is a methodological study to develop education program for families of patients with brain injury. Method: This education program is on the basis of education items identified in a previous research, and literature review, and again this was developed by educational program for families of patients with brain injury that consist of items which pass through proof of content validity of special group. This study established the goal of the study about selected items and made out a preliminary education program, and it was reviewed and corrected by evidence of content validity of the special group and the degree of difficulty. Results: The final education program content consists of 6 areas. : disease, cure and care, rehabilitation, family and others. Conclusion: This program will expect to be utilized to keep optimal health state, also it can prevent various problems from happening to patients with brain injury; moreover, we expect that it would improve the quality of life.

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Development of Population-based Prevention Strategies for Childhood Obesity: Applied WHO Model (아동.청소년 비만 예방을 위한 인구기반 예방 전략 개발:WHO 모형의 적용)

  • Kim, Ki-Rang;Lee, Eun-Young;Kim, Hye-Ryun
    • Korean Journal of Health Education and Promotion
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    • v.28 no.3
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    • pp.43-55
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    • 2011
  • Objectives: The objectives of this study were to describe population-based prevention strategies for childhood obesity and to discuss its application in a city in Korea. Methods: Literature review and empirical findings for ongoing programs were performed to develop population-based prevention strategies for childhood obesity with the framework and principles of WHO population-based prevention strategies for childhood obesity. Results: The developed framework had five key strategies (supportive policies, supportive environment, supportive program, strategic development & leadership, and monitoring & evaluation) under hierarchic objectives (long-term, middle-term and short-term) with the vision of healthy growth and development of all children and youth. Each strategy included evidence-based action plans with WHO principles. Conclusions: The developed strategies have advanced the existing strategies for childhood obesity prevention by providing the sustainable and systematic framework and action plans based on ecological approach. Further, the feasibility for operating the strategies needs to be verified.

The Effectiveness of Smoking Cessation Program in Adults: Systematic Review of Randomized Controlled Trials (성인 흡연자의 금연 프로그램 효과: 무작위대조군 실험연구의 체계적 문헌고찰)

  • Park, Seong-Hi;Hwang, Jeong-Hae;Choi, Yun-Kyoung;Kang, Chang-Bum
    • Korean Journal of Health Education and Promotion
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    • v.29 no.3
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    • pp.1-14
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    • 2012
  • Objectives: The purpose of this study was to determine if smoking cessation programs (SCPs) are effective for adults through a systematic review of the results of such programs in large randomized controlled trials (RCTs). Methods: The PICO (Patient, Intervention, Comparator, Outcome) strategy was established, 1,160 literature from domestic and foreign electronic databases was reviewed, and 22 references were selected based on the inclusion and exclusion criteria. The quality of each reference was evaluated using the Scottish Intercollegiate Guidelines Network tool, and meta-analysis was carried out. Results: The SCPs were significantly effective for adult smokers. Smoking cessation counseling, education, and smoking cessation medications such as nicotine patch were more effective than the other interventions. However, the results showed short-term effects (within six months), and differences were observed among the SCPs. For the outcome measures for SCPs, the abstinence rate of seven days was mainly used, but differences were identified between the CO level and the cotinine-verified abstinence rate of smoking cessation. Conclusions: For a smoking cessation program for adult smokers, the strength of the evidence of the program's effectiveness in RCTs that provide the identified intervention strategies should be considered.

An Integrative Review of Korean Nursing Studies on Pediatric Tonsillectomy (아동 편도선 절제술과 관련된 국내 간호연구의 통합적 고찰)

  • Yu, Kyoung Eun;Kim, Jin Sun
    • Child Health Nursing Research
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    • v.23 no.4
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    • pp.416-428
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    • 2017
  • Purpose: Tonsillectomy is a very common surgical procedure, particularly in children. The purpose of this study was to identify current evidence in nursing research on pediatric tonsillectomy by analyzing and evaluating Korean nursing studies related to pediatric tonsillectomy. Methods: An integrative literature review of Korean pediatric tonsillectomy research was conducted. Databases were searched to identify research that related to nursing care for pediatric tonsillectomy children. Results: Of the 115 studies identified, 13 studies met the inclusion criteria for this review. All studies were experimental studies and most of those studies had a quasi experimental design. No correlational studies or qualitative studies were found. Providing nursing information and education for children and their mothers at pre, during, and post tonsillectomy by pediatric nurses were found to be effective in reducing children's pain and anxiety and their mother's anxiety and uncertainty, and increasing children's appropriate sick role behaviors and their mother's satisfaction with nursing services provided and knowledge related to tonsillectomy. Conclusion: Although most studies reported positive effects in terms of post tonsillectomy outcomes, lack of methodological rigor limits the current evidences for pediatric tonsillectomy nursing interventions. Greater attention to improve methodological rigor for Korean research on pediatric tonsillectomy is needed.

Effect of chiral structure for free vibration of DWCNTs: Modal analysis

  • Asghar, Sehar;Naeem, Muhammad N.;Khadimallah, Mohamed Amine;Hussain, Muzamal;Iqbal, Zafar;Tounsi, Abdelouahed
    • Advances in concrete construction
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    • v.9 no.6
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    • pp.577-588
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    • 2020
  • In this paper, vibration attributes of chiral double-walled carbon nanotubes (CNTs) based on nonlocal elastic shell model have been investigated. The impact of small scale is being perceived by establishing Flügge shell model. The wave propagation is engaged to frame the ruling equations as eigen value system. The influence of nonlocal parameter subjected to different end supports has been overtly examined. A suitable choice of material properties and nonlocal parameter been focused to analyze the vibration characteristics. The new set of inner and outer tubes radii investigated in detail against aspect ratio and length. The dominance of boundary conditions via nonlocal parameter is shown graphically. Whereas for lower aspect ratio the frequencies coincide but as it continues to expand the difference between all respective boundary conditions slightly tend to increase. The results generated furnish the evidence regarding applicability of nonlocal shell model and also verified by earlier published literature.

Prevalence and Genotype Distribution of HPV among Women Attending a Cervical Cancer Screening Mobile Unit in Lampang, Thailand

  • Paengchit, Kannika;Kietpeerakool, Chumnan;Lalitwongsa, Somkiet
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.15
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    • pp.6151-6154
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    • 2014
  • A growing body of literature is evidence that identifying subtypes of high-risk human papillomavirus (HR-HPV) has impacted on various steps of cervical cancer prevention.Thus, it is mandatory to determine the background prevalence and distribution of HPV subtypes for designing and implementing area-specific management. The present study was conducted to evaluate prevalence and distribution of HPV subtypes among women aged 30-70 years living in Lampang, an area with a high incidence of cervical cancer, through use of a mobile screening unit. Of 2,000 women recruited in this study, 108 (5.40%, 95%CI: 4.45-6.48) were found to have HR-HPV infection. Risk was significantly correlated with age and number of partners. Singly or in combination, the most common genotype was HPV 52 (17.6%), followed by HPV 16 (14.81%), HPV 58 (13.89%), HPV 33 (11.11%), HPV 51 (11.11%), and HPV 56 (9.26%). HPV 18 was found in only 5.6% of cases. Together, HPV 16/18 were noted in approximately 20.4% of cases. Eighteen(16.67%) women were positive with multiple subtypes of HR-HPV. Co-infection most frequently involved HPV 16 or HPV 58. These findings have obvious implications for vaccine policy.

Development of the Forensic Nursing Competency Scale for Nurses (간호사의 법의간호 역량 측정도구 개발)

  • Jo, Na Young;Kim, Min Hye;Lee, Yun Mi
    • Journal of Korean Critical Care Nursing
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    • v.13 no.3
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    • pp.24-40
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    • 2020
  • Purpose : This study aims to develop the Forensic Nursing Competency Scale suitable to South Korea. Methods : The initial items were generated through literature review and interviews. Items were evaluated by experts for content and face validity. By conducting a pilot test, 74 measurement items were developed. In total, 333 copies of the questionnaire were analyzed regarding the validity and reliability of the study. Data were analyzed using SPSS 23.0 program and AMOS 18.0 program. Results : The study selected 53 questions after testing the content, face, and construct validity of the scale. The final 53 questions were composed of 15 sub-components in eight domains. These eight domains encompassed nursing practice, communication, critical thinking, human caring and relationships, evidence management, active information collection, professional development, and knowledge integration. Conclusions : In order to verify the effectiveness of the scale, future studies need to compare the forensic nursing competency in two groups to assess differences in these competency. Moreover, it is necessary to develop a forensic nursing educational program and validate its effectiveness by using this scale.

Effect of Particulate Matter on Human Health, Prevention, and Imaging Using PET or SPECT

  • Zaheer, Javeria;Jeon, Jongho;Lee, Seung-Bok;Kim, Jin Su
    • Progress in Medical Physics
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    • v.29 no.3
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    • pp.81-91
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    • 2018
  • Particulate matter (PM) in dust causes serious pathological conditions, and it has been considered a critical health issue for many years. Respiratory disorders such as bronchitis, asthma, and chronic inflammation, are the most common illnesses due to PM that appears as dust. There is evidence that cardiovascular and neurological abnormalities are caused by PM. Although an extensive amount of work has been conducted on this topic, including studies on the nature of the particles, particle size measurements, particle distribution upon inhalation, the health effects of fine particles, disease prevention, diagnosis, and treatment, to this date, there is still a considerable lack of knowledge in these areas. Therefore, the identification of the key components that cause diseases owing to PM, and the specific diagnoses of the diseases, is important. This review will explore the current literature on the origin and nature of PM and their effects on human health. In addition, it will also highlight the approaches that have been adopted in order to diagnose the effects of PM using positron emission tomography (PET) or single-photon emission computerized tomography (SPECT).