• Title/Summary/Keyword: liquid cell

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Liquid Biopsy: Current Status and Future Perspective in Gastric Cancer and Helicobacter Infection (액체 생검(Liquid Biopsy): 위암 및 헬리코박터 감염증에서 적응과 전망)

  • Kang, Eun A;Han, Young Min;Park, Jong Min;Yoo, In Kyung;Hong, Sung Pyo;Hahm, Ki Baik
    • The Korean journal of helicobacter and upper gastrointestinal research
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    • v.18 no.3
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    • pp.150-156
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    • 2018
  • Precision medicine stands for 4Ps - precise, preventive, participatory, and personal; in which "precision" is important because the current modern medicine starts from "trial and error," and "one does not fit all". Current targeted therapies for cancer have changed treatment approaches and led the precision medicine; however, clinical use of liquid biopsy, using blood or other liquid specimens to characterize circulating tumor cells (CTC) or tumor genes instead of biopsies of tumor tissues, still awaits availability of more information regarding non-invasive cancer detection and characterization, prediction of treatment response, monitoring the disease course and relapse possibilities, identification of mechanisms of drug resistance, and newer pathogenesis. In this review, we will introduce the basic concept of CTC, circulating cell free DNA, and exosomes and their possible application for gastric cancer relevant with Helicobacter pylori infection.

Liquid Moisture Management and Surface Properties of the Fabric in Transient Condition (작업복 소재 직물의 액상 수분 전달 특성 및 표면특성 연구)

  • 유신정
    • Journal of the Korean Society of Clothing and Textiles
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    • v.25 no.1
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    • pp.61-70
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    • 2001
  • As important factors determining human sensorial comfort, liquid moisture management and surface properties of heat resistant workwear materials were examined. To figure out liquid moisture management properties of the test materials, absorption capacity, rate of absorption, and evaporation properties were assessed. A modified GATS(Gravimetric Absorbency Testing System) was used to measure the liquid moisture accumulation associated with the wicking of liquid moisture from sweating skin. The GATS procedure measures demand wettability of materials to take up liquid in a direction perpendicular to the fabric surface and it was modified to incorporate a special test cell and cover to assess absorption behavior in the presence of evaporation. Fabric stiffness, smoothness, number and the length of surface fibers, and an estimate of the contact area between the skin and fabric surface were measured to characterize the mechanical and surface properties of the test materials. Also an estimate of the force with which a fabric clings to moist skin was made using as wet-cling index.

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Comparison of Cellular Features Diagnostic of Papillary Thyroid Carcinoma in Liquid-Based (Cell Scan 1500TM) Preparations and Conventional Smears

  • Lee, Jung Dal;Park, Yong Wook;Back, OunCheol;Jung, Pa Jong;Kim, Jong Yull
    • Korean Journal of Clinical Laboratory Science
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    • v.45 no.3
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    • pp.108-113
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    • 2013
  • The study compared the cytological features of papillary thyroid carcinoma (PTC) in liquid-based preparations (LBPs) and conventional Pap (CP) smears from fine needle aspiration (FNA), and assessed the feasibility of LBP using the Cell Scan $1500^{TM}$ processor on thyroid FNA samples. Thyroid FNA samples were obtained from 883 consecutive patients. Each sample was divided into two and used for LBPs and CP smears. All were screened independently in a double-blind manner. From the 883 cases, 95 cases were diagnosed as PTC in one or both types of preparation (10.8%). PTC was diagnosed via CP smears in 83 cases (87.4%) and via LBPs in 70 cases (73.7%). However, there were differences in categorization between the paired preparations: Twelve (12) PTCs were misinterpreted in CP smears and 25 PTCs in LBPs. There was a significant discrepancy in the rate of detection of the diagnostic features, with LBPs having a lower detection rate. One (1) case (1.2%) of CP smears and 16 cases (22.9%) of LBPs were categorized as unsatisfactory/nondiagnostic in a total of the 95 PTCs. To conclude, the detection rate of the diagnostic features of PTC is lower in Cell Scan 1500TM samples than in CP smears. However, there are some cases in which a diagnosis of PTC is made in LBPs, but not in CP smears. Therefore, definitive cancer diagnosis in thyroid FNA preparations is likely to result from agreement between direct smears and Cell Scan 1500TM preparations.

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A study on the transmittance-controlled liquid crystal cell (광 투과도 제어형 액정 셀 연구)

  • Yang, Seong-Soo;Kim, Phil-Jung;Oh, Byeong-Yun
    • Journal of IKEEE
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    • v.23 no.4
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    • pp.1224-1229
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    • 2019
  • In this study, a liquid crystal (LC) cell was manufactured for smart window applications, such as blinds, and a system for controlling the light transmission rate was developed. The threshold voltage of the LC cell was 1.325 V and when the transmission rate was 10%, the voltage showed 2.370 V, indicating that the LC cell manufactured is driven at low voltage. The LC cell also operated reliably after being heated for 10 min at 80℃. with a response time of less than 30ms. The operation system designed the applied voltage of the LC cell with a interval of about 0.5 V from 0.15 V to 3.53 V and confirmed that the light transmission rate of the LC varies depending on the actual applied voltage. These results suggest that LC cells are likely to be smart window applications.

Fast Switching of a Polymer-networked Twisted Nematic Liquid Crystal Cell (폴리머 네트워크가 형성된 TN 액정셀의 고속응답 특성)

  • Jin, Hye-Jung;Kim, Ki-Han;Baek, Jong-In;Kim, Jae-Chang;Yoon, Tae-Hoon
    • Korean Journal of Optics and Photonics
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    • v.21 no.2
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    • pp.69-73
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    • 2010
  • We propose a method to enhance the response time of a twisted nematic liquid crystal (TN-LC) cell using an anisotropic polymer. Polymer networks are formed by the phase separation between a LC and a UV-curable polymer. A TN-LC cell is exposed to UV light after the mixture of LC and anisotropic polymer is injected into the TN-LC cell. As a result, turn-off time of a TN-LC cell can be decreased remarkably without any loss of the transmittance. The turn-off time of a TN-LC cell with pure LC was 16 ms, but those of polymer networked TN-LC cells were 12, 11, and 9 ms when the concentration of the polymer was 3, 5, and 10 wt%, respectively. Moreover, by virtue of the polymer network, the backflow effect and the delay time generated during the turn-off process disappeared.

Optimization of liquid-liquid extraction conditions for paclitaxel separation from plant cell cultures (식물세포배양으로부터 Paclitaxel 분리를 위한 액-액 추출 조건의 최적화)

  • Kim, Jin-Hyun
    • KSBB Journal
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    • v.24 no.2
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    • pp.212-215
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    • 2009
  • In this study, the process parameters of liquid-liquid extraction were optimized to obtain a high purity and yield of paclitaxel in a pre-purification step. The optimal solvent ratio (methylene chloride/concentrated methanol extract ratio), extraction times, mixing time, and standing time for liquid-liquid extraction were 0.28 (v/v), 3(times), 30 min, and 40 min, respectively. The polar impurities from the biomass extraction were efficiently removed by liquid-liquid extraction. The complete concentration of liquid-liquid extract by rotary evaporator was reliable enough to obtain a high purity and yield of paclitaxel for subsequent purification steps.

A New Ionic Liquid for a Redox Electrolyte of Dye-Sensitized Solar Cells

  • Kang, Man-Gu;Ryu, Kwang-Sun;Chang, Soon-Ho;Park, Nam-Gyu
    • ETRI Journal
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    • v.26 no.6
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    • pp.647-652
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    • 2004
  • A new ionic liquid, 1-vinyl-3-heptylimidazolium iodide (VHpII), was synthesized and applied as a redox electrolyte for dye-sensitized solar cells. The chemical structure of the synthesized VHpII was confirmed using $^1H$ NMR. Thermogravimetric analysis showed that the VHpII was stable for thermal stress of up to $250^{\circ}C$. The energy conversion efficiencies of the VHpII-based dye-sensitized solar cells were investigated in terms of the effect of a lithium iodide addition. A solar cell containing the redox couple of VHpII and iodine showed a conversion efficiency of 2.63% under 1 sun light intensity at AM 1.5. Adding 0.4 M LiI results in a conversion efficiency of 3.63%, which was an improvement of about 40%. The increased conversion efficiency was ascribed to an increase in external quantum efficiency.

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Solution-Derived Hafnium Lanthanum Oxide Films Prepared Using Ion-Beam Irradiation and Their Applications as Alignment Layers for Twisted-Nematic Liquid Crystal Displays

  • Oh, Byeong-Yun
    • Transactions on Electrical and Electronic Materials
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    • v.17 no.6
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    • pp.355-358
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    • 2016
  • We present the alignment characteristics of LC (liquid crystal) molecules on solution-derived HLO (hafnium lanthanum oxide) films fabricated using IB (ion-beam) irradiation. We then demonstrated that LC molecules can be homogeneously and uniformly aligned on the HLO film irradiated at an IB incident energy of 1.2 keV. Physicochemical analysis methods such as atomic force microscopy and X-ray photoelectron spectroscopy were used to verify the LC alignment mechanism on the IB-irradiated HLO film. In addition, the electro-optical performance of a TN (twisted-nematic) cell fabricated using the IB-irradiated HLO film exhibited characteristics superior to those of the conventional TN cell fabricated using a rubbed polyimide layer.

Single-panel simulation on liquid crystal on silicon

  • Liao, Engle;Chiu, Jack;Peng, James
    • 한국정보디스플레이학회:학술대회논문집
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    • 2004.08a
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    • pp.939-942
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    • 2004
  • In this study, we report simulation results of single-panel LCOS (liquid crystal on silicon). Reflective LCOS microdisplays are widely used in various projection and near-eye application. For one panel system, liquid crystal response time is an important variable. The panel must switch fast enough to support the display of Field color sequential with high field rates. In order to have fast response and good contrast, a vertical alignment (VA) cell was used in this study. With suitable selection on LC parameters like temperature, viscosity, elastic constant and birefringence, it is possible to get response time of around 2ms from a 2.0 um-thick vertical alignment cell. This result also indicates an ease of production control on 2.0 um cells than 1.0 um cells.

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