• Biomedical Science Letters
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• v.15 no.1
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• pp.67-72
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• 2009

Microtubule-interfering agents (MIAs), including paclitaxel, have been attributed in part to interference with microtubule assembly, impairment of mitosis, and changes in cytoskeleton. But the signaling mechanisms that link microtubule disarray to destructive or protective cellular responses are poorly understood. This study investigated the effect of paclitaxel on differentiation such as type II collagen expression and sulfated proteoglycan accumulation in rabbit articular chondrocytes. Paclitaxel caused differentiated chondrocyte phenotype as demonstrated by increment of type II collagen expression and proteoglycan synthesis Paclitaxel treatment stimulated activation of ERK-1/2 and p38 kinase. Inhibition of ERK-1/2 with PD98059 enhanced paclitaxel-induced differentiation, whereas inhibition of p38 kinase with SB203580 suppressed paclitaxel-induced differentiation. Our findings suggest that ERK-1/2 and p38 kinase oppositely regulate paclitaxel-induced differentiation in chondrocytes.

• Journal of Communications and Networks
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• v.9 no.3
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• pp.236-246
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• 2007

This paper investigates the performance of the transmission control protocol (TCP) transport protocol over IEEE 802.11 infrastructure based wireless networks. A wireless link is generally characterized by high transmission errors, random interference and a varying latency. The erratic packet losses usually lead to a curbing of the flow of segments on the TCP connection and thus limit TCP's performance. This paper examines the impact of the lossy nature of IEEE 802.11 wireless networks on the TCP performance and proposes a scheme to improve the performance of TCP over wireless links. A negative acknowledgment scheme, selective negative acknowledgment (SNACK), is applied on TCP over wireless networks and a series of ns-2 simulations are performed to compare its performance against that of other TCP schemes. The simulation results confirm that SNACK and its proposed enhancement SNACK-S, which incorporates a bandwidth estimation model at the sender, outperform conventional TCP implementations in 802.11 wireless networks.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.22 no.4
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• pp.804-811
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• 1997

In the CDMA mobile communication system, reverse power control can be used to minimize the interference level for a good quality of the voice channel, and used to maxmize the system capacity. In this paper, we have analyed the environment of the K-parameter and the access procedure for the mobile station, and proposed a new algorithm for the access probe procedure of the station. K-parameter is determined according to the environment of the base station and access probe can adaptively control the power according to the position changes of the mobile station or the rapid and various state changes of the channel. Simulation results in the limited test environment show that it can increase the system capacity and decrease the power comsumption of the mobile station while maintaining the good and stable quality of the voice channel.

• 제어로봇시스템학회:학술대회논문집
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• 2001.10a
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• pp.65.4-65
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• 2001

In case of data transmission using the upper 10GHz frequency, rain results in attenuation of radio waves. And the most serious atmospheric effect in a satellite link is the rainfall. The attenuation of rainfall very seriously affects the quality of transmission line. Because the rain increases thermal noise and interference, and decreases the amplitude of the signal. KOWACO manages the VSAT system instead of VHF network for communication of rain and water-level data from 1998. The purpose of this system is to monitor the change of water-level and rain data during a flood duration. VHF system acquires the data by a call per a hour. But the satellite network obtains the data whenever event data occur. Thus the satellite network is more powerful than the VHF system. In study ...

• International journal of advanced smart convergence
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• v.8 no.3
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• pp.61-68
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• 2019

Spatial modulation (SM) is the first proposed space modulation technique. By further utilizing the quadrature spatial dimension, quadrature spatial modulation (QSM) has been developed as an amendment to SM system to enhance the overall spectral efficiency. Both techniques are capable of entirely eliminating interchannel interference (ICI) at the receiver. In this paper, we propose a simple adaptive hybrid switching transmission scheme to obtain better system performance than SM and QSM systems under a fixed transmission date rate. The presented modulator selection criterion for switching between spatial modulator and quadrature spatial modulator is based on the larger received minimum distance of spatial modulator and quadrature spatial modulator to exploit the spatial channel freedom. It is shown through Monte Carlo simulations that the proposed hybrid SM and QSM switching system yields lower error performance than the conventional SM and QSM systems under the same fixed data rate and thus can provide signal to noise ratio (SNR) gain.

• Journal of KIISE:Computing Practices and Letters
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• v.16 no.4
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• pp.421-426
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• 2010

Due to the ease of deployment and the extended coverage, wireless mesh networks (WMNs) are gaining popularity and research focus. For example, the routing protocols that enhance the throughput on the WMNs and the link quality measurement schemes are among the popular research topics. However, most of these works assume that the locations of the mesh routers are predetermined. Since the operators in an Indoor mesh network can determine the locations of the mesh routers by themselves, it is essential to the WMN performance for the mesh routers to be initially placed by considering the performance issues. In this paper, we propose a mesh router placement scheme based on genetic algorithms by considering the characteristics of WMNs such as interference and topology. There have been many related works that solve similar problems such as base station placement in cellular networks and gateway node selection in WMNs. However, none of them actually considers the interference to the mesh clients from non-associated mesh routers in determining the locations of the mesh routers. By simulations, we show that the proposed scheme improves the performance by 30-40% compared to the random selection scheme.

• Journal of the Institute of Electronics and Information Engineers
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• v.53 no.9
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• pp.18-25
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• 2016

In D2D communications underlaying a multicell network, it is of primary importance to ensure coexistence of cellular links and D2D links with minimal interference. Therefore, resource allocation scheme for D2D links should be designed to limit the interference between cellular links and D2D links. In this paper, we propose an effective resource allocation scheme for multiple D2D links which share the uplink spectrum resource with cellular users in a multicell network. Under the assumption that the locations of users are known to the base station, the proposed scheme allocates cellular resources to D2D links, such that the interference between a cellular link and multiple D2D links is minimized. In particular, we compute two constants from the path loss model and then use the constants to protect both cellular and D2D links. Simulation results are provided to verify the performance of the proposed scheme.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.42 no.5 s.335
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• pp.55-62
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• 2005

In this paper, we propose an efficient symbol detection algorithm for space-frequency OFDM (SF-OFDM) transmit diversity scheme and present the implementation results of the SF-OFDM WLAN baseband processor with the proposed algorithm. When the number of sub-carriers in SF-OFDM scheme is small, the interference between adjacent sub-carriers may be generated. The proposed algorithm eliminates this interference in a parallel manner and obtains a considerable performance improvement over the conventional detection algorithm. The bit error rate (BER) performance of the proposed detection algorithm is evaluated by the simulation. In the case of 2 transmit and 2 receive antennas, at $BER=10^{-4}$ the proposed algorithm obtains about 3 dB gain over the conventional detection algorithm. The packet error rate (PER), link throughput, and coverage performance of the SF-OFDM WLAN with the proposed detection algorithm are also estimated. For the target throughput at $80\%$ of the peak data rate, the SF-OFDM WLAN achieves the average SNR gain of about 5.95 dB and the average coverage gain of 3.98 meter. The SF-OFDM WLAN baseband processor with the proposed algorithm was designed in a hardware description language and synthesized to gate-level circuits using 0.18um 1.8V CMOS standard cell library. With the division-free architecture, the total logic gate count for the processor is 945K. The real-time operation is verified and evaluated using a FPGA test system.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.23 no.7
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• pp.1797-1806
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• 1998

Future satellite communication systems will be developed at Ka-band (20/30 GHz) owing to the relatively wide frequency allocation and current freedom from terrestrial interference for multimedia services. A serious disadvantage of the Ka-band, however, is the very high atmospheric attenuation in rainy weather. Synchronous CDMA drastically redces the effect of self-noise with several interesting features of CDMA for mobile communications such as fixible freuqncy rese, the capability of performin soft-handover and a lower sensitivity to interference. This paper evaluates the performance of a synchronous CDMA reture link for a Ka-band geostationary satellite communication system. For a fixed satellite channel whose characteristics depend on weather conditions, the signal envelope and phase for this channel is modelled as Gaussian. The bit error and outage probability, and the detection loss due to imperfect chip timing synchronization is analytically evaluated and the system capacity degaradation due to the weather condition is estimated. The two cases consist of the general case in which all users are affected by rain condition, and the worst case in which the reference user is only affected by rain attenuation. the results for two cases of rain condition clearly show that synchronous CDMA eases the power control requirements and has less sensitivity to imperfect power control.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.27 no.7B
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• pp.673-685
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• 2002

In this paper, we analyze the pros and cons of the fast power control to the forward link in the environments where mixed traffics of voice and data produce the transmitted/received power difference. We propose the Zone-based power control scheme that can improve the performance of the fast power control scheme in the viewpoint of the resource allocation. The proposed scheme is a mechanism that controls both the power and rate of non-realtime data traffics according to location distribution of the mobile stations. The scheme is based on the conventional fast power control scheme in the CDMA systems, and it adaptively controls the transmission rate of each data traffic. Zone-based rate control of data call brings about somewhat power margin to the call. As a result, the proposed scheme saves the power consumption of portables and reduces the amount of interference. With the proposed scheme, not only be extended the service coverage of high-rate traffic to the entire cell service coverage, but also the QoS of low-rate traffic can keep going through the service time, especially, in the situation that the amount of incoming interference is much larger. The experimental results show that the proposed scheme yields a improved performance compared with the conventional scheme in terms of the power consumption and traffic throughput of portables, especially, with the increasing number of high-rate data traffics.