• Structural Engineering and Mechanics
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• 제25권5호
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• pp.565-576
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• 2007

The article describes a technique for the measurement of the level of complexity of fracture surfaces by the method of vertical sections, and a performed statistical analysis of the effect of profile lines on the fractographic and fractal parameters of fractures, i.e. the profile line development factor, $R_L$, and the fracture surface development factor, $R_S$, (as defined by the cycloid method), as well as the fractal dimension, $D_C$, (as determined by the chord method), and the fractal dimension, $D_{BC}$, (as determined by the box method). The above-mentioned parameters were determined for fracture surfaces of basalt and gravel concretes, respectively, which had previously been subjected to fracture toughness tests. The concretes were made from mixtures of a water/cement ratio ranging from 0.41 to 0.61 and with a variable fraction of coarse aggregate to fine aggregate, $C_{agg.}/F_{agg.}$, in the range from 1.5 to 3.5. Basalt and gravel aggregate of a fraction to maximum 16 mm were used to the tests. Based on the performed analysis it has been established that the necessary number of concrete fracture profile lines, which assures the reliability of obtained testing results, should amount to 12.

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 1994년도 춘계학술대회 and 제3회 신약개발 연구발표회
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• pp.129-130
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• 1994

The science of toxicology is the understanding of the mechanisms by which exogenous agents produce deleterious effects in biological systems. The actions of chemicals such as drugs are ultimately exerted at the cellular and gene levels. Over the past decade. several in vitro alternative methods such as cultured cells for assessing the toxicity of various xenobiotics have been proposed to reduce the use of animals. In this workshop three advanced methods will be presented. These methods are novel important models for toxicologic studies. Dr. Tabuchis group has establishcd two immortalized gastric surface mucosa cell lines from the pminary cultore of gastric fundic mucosal cells of adult transgenic mice harboring a temperature sensitive simian virus 40 large T-anugen gene. As the immortalized cell lines of various tissues possess unique characteristics to maintain their normal functions for several months, these cell lines are extremely useful for not only toxicity testing but also pharmacological screening in new drug development. Professor Funatsu have studied the formation of spherical multicelluar aggregates of adult rat hepatocytes(spheroid) having tissue like structure. The sphcroid shown thre is a prototype module of an artificial liver support system. Thus, the urea synthesis activity of the artificial liver was maintained at least to days in 100％ rat blood plasma. Dr. Takezawa and his coworkers have developed a novel culture system of multicellular spheroids considered 〃organoids〃 by utilizing a thermo-responsive polymer as a substratum of anchorage dependent cells. His final goal is to reconstitute the organoids of various normal organs, e.g., liver, skin etc. and also abnormal deseased organs such as tumor.

• Journal of Microbiology and Biotechnology
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• 제25권4호
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• pp.439-447
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• 2015

The objective of this study was to isolate and identify the chemical structure of a biosurfactant produced by Nocardia farcinica strain BN26 isolated from soil, and evaluate its in vitro antitumor activity on a panel of human cancer cell lines. Strain BN26 was found to produce glycolipid biosurfactant on n-hexadecane as the sole carbon source. The biosurfactant was purified using medium-pressure liquid chromatography and characterized as trehalose lipid tetraester (THL) by nuclear magnetic resonance spectroscopy and mass spectrometry. Subsequently, the cytotoxic effects of THL on cancer cell lines BV-173, KE-37 (SKW-3), HL-60, HL-60/DOX, and JMSU-1 were evaluated by MTT assay. It was shown that THL exerted concentration-dependent antiproliferative activity against the human tumor cell lines and mediated cell death by the induction of partial oligonucleosomal DNA fragmentation. These findings suggest that THL could be of potential to apply in biomedicine as a therapeutic agent.

• Journal of electromagnetic engineering and science
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• 제10권3호
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• pp.92-98
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• 2010

A new wideband bandstop filter(BSF) with a sharp roll-off characteristic is introduced in a stripline structure in this paper. The BSF consists of two sections: the first is two capacitively coupled $\lambda/4$ short-circuited lines with opposite ground positions, while the second is a capacitively coupled $\lambda/4$ short-circuited line. The BSF provides three transmission zeros within the stopband and better than 22 dB rejection over the whole wireless local area network (WLAN) band from 5.15 to 5.825 GHz. The BSF, cascaded to an U.S. ultra-wideband(UWB: 3.1~10.6 GHz) band-pass filter(BPF), is simulated with HFSS and realized with low-temperature co-fired ceramic(LTCC) green tape with a dielectric constant of 7.8. The measurement results agree well with the HFSS simulation results. The size of the UWB BPF including the BSF is $3{\times}6.3\times0.45\;mm^3$.

• 한국산학기술학회논문지
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• 제12권5호
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• pp.2298-2304
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• 2011

본 논문에서는 공통 결함접지구조(common defected ground structure, CDGS)를 이용한 초고주파 대역의 저역통과여파기(low pass filter, LPF) 소형화 설계에 대하여 기술한다. 기존의 연구에서는 표준형 LPF보다 약간 소형화된 DGS 적용의 LPF를 설계하는 방법을 제시하는데 그쳤으나, 본 논문에서는 공통 DGS 구조를 이용하여 종래의 회로보다 절반의 크기로 줄이는 방법을 제시한다. 공통 DGS는 양면의 마이크로스트립 전송선로의 공통 접지면에 구현된다. 본 논문에서는 예로써, 비유전율이 2.2이고 두께가 31mils인 유전체 기판을 이용하여 양면 마이크로스트립 전송선로 구조와 공통 DGS를 구성하고, 이를 활용하여 소형화된 LPF를 설계하고, 실제로 제작 및 측정하여 제안하는 방법의 타당성을 검증한다. 최종적으로 설계된, 공통 DGS를 지니는 LPF는 기존의 단층 구조에서 DGS를 지니는 LPF에 비하여 52.6%의 크기를 가지면서도, 측정된 성능은 반사계수가 -22dB 이하이고 삽입손실이 0.19dB 이하로 여전히 우수함을 보여준다.

• 한국소프트웨어감정평가학회 논문지
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• 제17권2호
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• pp.151-159
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• 2021

도표로 작성된 양식 문서에서 도표의 레이아웃 해석에 필요한 그리드 라인을 추출하기 위해 다양한 필터링 또는 모폴로지 등의 방법을 사용하여 직선 성분을 선명하게 개선시키기 위한 연구들이 많이 진행되고 있다. 도표의 직선 성분을 선명화하더라도 직선 내부에 절단 점들이 존재하거나 기울어진 경우에는 직선 추출이 어렵고 도표 셀들의 레이아웃을 논리적으로 표현하는데 여전히 어려움을 겪을 수 있다. 본 연구에서는 직선에 절단점들이 존재하거나 기울어져도 직선을 검출할 수 있는 라인 추적 알고리즘을 제안하였다. 이를 이용하여 그리드 라인을 추출하고 라인들의 교차점 및 셀 정보들을 찾아 도표의 구조를 분석할 수 있는 알고리즘을 마련하였다. 제안한 알고리즘을 실제 양식 문서 영상을 대상으로 실험한 결과 평균 0.41초 처리시간에 96.4%의 도표 구조를 분석할 수 있음을 확인하였다.

• 천문학회보
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• 제36권2호
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• pp.102.1-102.1
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• 2011

In this study we use three-dimensional magnetohydrodynamic simulations to investigate how the dynamic state of emerging magnetic field is related to the twist of field lines. Emerging magnetic field forms a magnetic structure on the Sun where various kinds of activity such as solar flares, jets, and coronal mass ejections are observed. To understand the physical mechanism for producing such activity, we have to know the dynamic nature of this structure. Since flares are the manifestation of rapidly dissipating electric current in the corona, we also investigate the distribution of current density inside the structure and examine how it depends on the field-line twist. To demonstrate the dynamic structure of emerging magnetic field, we focus on the factors characterizing the geometric property and stratification of emerging magnetic field, such as the curvature of field line and the scale height of field strength. These two factors show that emerging field forms a two-part structure in which the central part is close to a force-free state while the outer marginal part is in a fairly dynamic state where magnetic pressure force is dominant. We discuss how the field-line twist affects the two-part structure and also explain a possible relation between electric current structure and sigmoid observed in a preflare phase.

• 천문학회지
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• 제37권5호
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• pp.601-603
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• 2004

We present the results of the linear analysis for the Parker-Jeans instability in the magnetized gas disks including the effect of cosmic-ray diffusion along the magnetic field lines. We adopted an uni-formly rotating two temperature layered disk with a horizontal magnetic fields and solved the perturbed equations numerically. Fragmentation of gases takes place and filamentary structures are formed by the growth of the instability. Nagai et al. (1998) showed that the direction of filaments being formed by the Parker-Jeans instability depends on the strength of pressure outside the unperturbed gas disk. We found that at some range of external pressures the direction of filaments is also governed by the value of the diffusion coefficient of CR along the magnetic field lines k.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2007년도 춘계학술대회 논문집
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• pp.1864-1874
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• 2007

Korean trains pass many mountain areas, so the volume of structures like bridge and tunnel has large part of railway lines. Train speed-up naturally needs a straight line in railway, then structures are increasing, and the length of structure has more than 70% in Kyongbu high-speed railway. The stiffness of bridge and tunnel is higher than the soil in the roadbed in spite of dynamic difference in vibration and displacement. Differences in stiffness have more dynamic effects and increase the deformation and destruction in the track and roadbed. This influences passenger's comfort and the safety of operation, and it needs more track maintenance. This study selected tunnel with ballast track, tunnel with concrete track, and structure's approaches with short maintenance cycle in the roadbed and had track acceleration tests and track liner inspections using track master in the field. This study will measure periodically to structure's approaches which have very fast track irregularity and analyze dynamic differences and track irregularity near structure's approaches, so realize the cause of track irregularity of structure's approaches and use basic data for reasonably strengthening method of structure's approaches.

• Journal of electromagnetic engineering and science
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• 제13권4호
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• pp.245-250
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• 2013

This paper presents a tunable bandpass filter based on the varactor-loaded composite right- and left-handed transmission line (CRLH-TL). The proposed filter is composed of one CRLH-TL unit cell, which corresponds to the third-order bandpass filter. The tunable bandpass filter is designed using only lumped-elements. The use of lumped elements saves space and lowers the fabrication cost. The size of the proposed tunable bandpass filter is $17mm{\times}5mm$, neglecting the feed lines and DC lines. All of the varactors are controlled by one DC bias. The center frequency of the bandpass filter can be controlled by varying the value of the varactors. The tunable range of the center frequency is from 412.5 to 670 MHz. The insertion loss is less than 3 dB, the return loss is more than 10 dB in the passband.