• 제목/요약/키워드: lines of the structure

검색결과 1,157건 처리시간 0.033초

Differential Expression of O-glycoprotein Glycans in Cholangiocarcinoma Cell Lines

  • Talabnin, Krajang;Talabnin, Chutima;Ishihara, Mayumi;Azadi, Parastoo;Wongkham, Sopit;Sripa, Banchob
    • Asian Pacific Journal of Cancer Prevention
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    • 제17권2호
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    • pp.691-695
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    • 2016
  • Protein glycosylation is the most common posttranslational modification in mammalian cells. Aberrant protein glycosylation has been reported in various diseases, including cancer. We identified and quantified the glycan structures of O-linked glycoprotein from cholangiocarcinoma (CCA) cell lines from different histological types and compared their profiles by nanospray ionization-linear ion trap mass spectrometry (NSI-$MS^n$). Five human CCA cell lines, K100, M055, M139, M213 and M214 were characterized. The results showed that the O-linked glycans of the CCA cell lines comprised tri- to hexa-saccharides with terminal galactose and sialic acids: NeuAc1Gal1GalNAc1, Gal2GlcNAc1GalNAc1, NeuAc2Gal1GalNAc1 NeuAc1Gal2GlcNAc1GalNAc1 and NeuAc2Gal2GlcNAc1GalNAc1 All five CCA cell lines showed a similar glycan pattern, but with differences in their quantities. NeuAc1Gal1GalNAc1 proved to be the most abundant structure in poorly differentiated adenocarcinoma (K100; 57.1%), moderately differentiated adenocarcinoma (M055; 42.6%) and squamous cell carcinoma (M139; 43.0%), while moderately to poorly differentiated adenocarcinoma (M214; 40.1%) and adenosquamous cell carcinoma (M213; 34.7%) appeared dominated by $NeuA_{c2}Gal_1GalNA_{c1}$. These results demonstrate differential expression of the O-linked glycans in the different histological types of CCA. All five CCA cell lines have abundant terminal sialic acid (NeuAc) O-linked glycans, suggesting an important role for sialic acid in cancer cells. Our structural analyses of glycans may provide important information regarding physiology of disease-related glycoproteins in CCA.

탄성지지된 구조물의 충격 햄머 실험에서 질량선의 개선을 통한 향상된 강체 특성 규명법 (Identification of Rigid Body Properties of the Mounted Structure with Improved Mass-Lines from Impact Hammer Tests)

  • 안세진;정의봉;황대선
    • 한국소음진동공학회:학술대회논문집
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    • 한국소음진동공학회 2002년도 추계학술대회논문집
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    • pp.317-322
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    • 2002
  • There are many researches to identify the rigid body properties from the mass-line obtained by impact hammer testing. The correct rigid body properties of the structure may be estimated if the mass-line of the structure could be obtained exactly. When the structure is mounted by elastic materials, the mass-line cannot be read correctly from the impulse response spectrum. The reason is due to the effects of rigid body modes of mounted structure. In this paper, the effects of rigid body modes of mounted structure to the mass-line are discussed and the method to remove these effects is also presented.

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A Fine-scale Half Ring-like Structure around a Pore

  • 송동욱;채종철
    • 천문학회보
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    • 제38권2호
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    • pp.87.2-87.2
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    • 2013
  • We studied a fine-scale half ring-like structure around a pore seen from the high spectral and the high spatial resolution data. Our observations were carried out using the Fast Imaging Solar Spectrograph (FISS) and the InfraRed Imaging Magnetograph (IRIM) installed at the 1.6 meter New Solar Telescope of Big Bear Solar Observatory (BBSO) on 2012 July 19. During the observations, we found a fine-scale half ring-like structure located very close to a pore (~0.4 arcsec apart from the pore). It was seen in the far wing images of the $H{\alpha}$ and Ca II $8542{\AA}$ lines, but it was not seen in the line center images of two lines. The length of the structure is about 4200 km and the width is about 350 km. We determined its line-of-sight velocity using the Doppler shift of the centroid of the Ti II line ($6559.6{\AA}$, close to the $H{\alpha}$ line) and determined horizontal velocity using the NAVE method. we also investigated the magnetic configurations using the Stokes I, Q, U, and V maps of the IRIM. As a results, we found that it has a high blue-shift velocity (~2km) faster than the photospheric features and has a strong horizontal component of the magnetic field. Based on our findings, we suggest that it is associated with small flux emergence, which occurs very close to the pore. Even though it is very small structure, this kind of magnetic configuration can be in chare of the upper chromosphere heating, especially above the pore.

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π-형 전송선 급전 구조를 갖는 대역 통과 필터 (A Band Pass Filter with Feeding Structure Using π-Type Transmission Line)

  • 배주석;임종식;김귀수;안달
    • 한국전자파학회논문지
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    • 제19권2호
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    • pp.114-120
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    • 2008
  • 본 논문에서는 일반적인 반 파장 평행 결합 선로 대역 통과 필터의 입 출력 결합 선로를 K-인버터로 변환하고, K-인버터를 $\pi$-형 전송선 등가로 대체함으로써 $\pi$-형 전송선 급전 구조를 갖는 구조의 대역 통과 필터를 제안하였다. 이 방법은 반 파장 결합 선로 대역 통과 필터의 입 출력 결합 선로 구현 문제에 대한 해결 방안을 제시한다. 또한, 기존의 탭 선로(tapped line) 구조의 설계 방법에 비해 설계 식이 매우 간단하고 정확하여, 특성의 적정화를 위한 노력과 시간을 상당히 줄일 수 있다. 제안된 이론을 바탕으로 $\pi$-형 전송선 급전 구조를 갖는 구조의 대역 통과 필터를 설계 및 제작하였고, 그 결과로부터 제안 방법의 타당성을 입증하였다.

A Study on Improvement of the Transmittance in the Fringe-Field Switching (FFS) Mode

  • Lee, J.Y.;Ryu, J.W.;Lee, S.H.
    • 한국정보디스플레이학회:학술대회논문집
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    • 한국정보디스플레이학회 2006년도 6th International Meeting on Information Display
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    • pp.621-624
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    • 2006
  • Pixel structure of the fringe-field switching (FFS) mode to improve transmittance has been studied. New FFS structures related to the electrode structure at the edges of pixel, and the pixel electrode width and distance between electrodes was optimized. The former improves transmittance by minimizing the region of disclination lines. The latter improves it by increasing light efficiency above center of electrodes and also response time.

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Molecular modeling study of indeno[1,2-c]isoquinolines and 3-arylisoquinolines using CoMFA

  • Kang, Sung-Kyung;Manhk, Le-Quynh;Cho, Won-Jea
    • 대한약학회:학술대회논문집
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    • 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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    • pp.171.1-171.1
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    • 2003
  • ·The potent antitumor activities of 3-arylisoquinolines promoted us to explore the structure-activity relationship of these compounds. A series of 3-arylisoquinoline derivatives were evaluated for antitumor cytotoxicity against human lung tumor cell (A 549). For the next stage, we decided to prepare the constrained form of 3-arylisoquinolines as indeno[1,2-c]isoquinolines. As a result, diverse spectrum against human tumor cell lines was obtained. In order to study structure-activity relationship (SAT) of these compounds the comparative molecular field analysis (CoMFA) was carried out. (omitted)

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형광등용 안정기의 발화 및 용융흔 분석에 관한 연구 (A Study on the Ignition and Molten Mark Analysis of Ballast for Fluorescent Lamp)

  • 최충석;박창수;김혁수;김향곤;정재희
    • 한국산업안전학회:학술대회논문집
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    • 한국안전학회 1998년도 추계 학술논문발표회 논문집
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    • pp.173-177
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    • 1998
  • In this paper, we reported an outbreak of fire hazard of ballast for fluorescent lamp. The surface structure and composition of ballast coil analyzed by using metallurgical microscope, scanning electron microscope(SEM) and energy dispersive x-ray spectroscopy(EDX). The surface of molten mark appeared columnar structure and void. EDX analysis indicated that the molten mark spectra were composed not only of the corresponding original spectra but also of several new lines.

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조합논리회로의 고장 검출율 개선을 위한 회로분할기법 (Circuit partitioning to enhance the fault coverage for combinational logic)

  • 노정호;김상진;이창희;윤태진;안광선
    • 전자공학회논문지C
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    • 제35C권4호
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    • pp.1-10
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    • 1998
  • Partitioning problem of large combinational logic has been studied in real world. Most of logic include undectable faults from the structure of it's redundant, fan-out-reconvergent, and symetrical feature. BPT algorithm is proposed to enhance the fault voverage for combinational logic partitioning. This algorithm partitions the logic by cut the lines related to undetectable structure when seperating. Controllability and observability are considered in the process of partitioning. This algorithm is evaluated effective by testing ISCAS85 circuits.

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Simplification of LIDAR Data for Building Extraction Based on Quad-tree Structure

  • Du, Ruoyu;Lee, Hyo Jong
    • 한국정보처리학회:학술대회논문집
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    • 한국정보처리학회 2011년도 추계학술발표대회
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    • pp.355-356
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    • 2011
  • LiDAR data is very large, which contains an amount of redundant information. The information not only takes up a lot of storage space but also brings much inconvenience to the LIDAR data transmission and application. Therefore, a simplified method was proposed for LiDAR data based on quad-tree structure in this paper. The boundary contour lines of the buildings are displayed as building extraction. Experimental results show that the method is efficient for point's simplification according to the rule of mapping.

Trinocular 정합과 DEM 변환식을 이용한 차폐지역이 포함된 인공지물의 높이 추출 (Height extraction of the man-made structure including occluded region using trinocular matching and DEM mapping)

  • 김지태;엄기문;이쾌희
    • 제어로봇시스템학회:학술대회논문집
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    • 제어로봇시스템학회 1996년도 한국자동제어학술회의논문집(국내학술편); 포항공과대학교, 포항; 24-26 Oct. 1996
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    • pp.260-263
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    • 1996
  • THe Purpose of this paper is to match the feature point of man-made structure and to obtain the DEM which are occluded in a image plane. We use the trinocular matching with epipolar lines and planes. If an occlusion appears at one of the trinocular images, the DEM mapping is used to estimate the height of feature points in it.

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