• Title/Summary/Keyword: linearity analysis

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Linearity Estimation of PET/CT Scanner in List Mode Acquisition (List Mode에서 PET/CT Scanner의 직선성 평가)

  • Choi, Hyun-Jun;Kim, Byung-Jin;Ito, Mikiko;Lee, Hong-Jae;Kim, Jin-Ui;Kim, Hyun-Joo;Lee, Jae-Sung;Lee, Dong-Soo
    • The Korean Journal of Nuclear Medicine Technology
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    • v.16 no.1
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    • pp.86-90
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    • 2012
  • Purpose: Quantification of myocardial blood flow (MBF) using dynamic PET imaging has the potential to assess coronary artery disease. Rb-82 plays a key role in the clinical assessment of myocardial perfusion using PET. However, MBF could be overestimated due to the underestimation of left ventricular input function in the beginning of the acquisition when the scanner has non-linearity between count rate and activity concentration due to the scanner dead-time. Therefore, in this study, we evaluated the count rate linearity as a function of the activity concentration in PET data acquired in list mode. Materials & methods: A cylindrical phantom (diameter, 12 cm length, 10.5 cm) filled with 296 MBq F-18 solution and 800 mL of water was used to estimate the linearity of the Biograph 40 True Point PET/CT scanner. PET data was acquired with 10 min per frame of 1 bed duration in list mode for different activity concentration levels in 7 half-lives. The images were reconstructed by OSEM and FBP algorithms. Prompt, net true and random counts of PET data according to the activity concentration were measured. Total and background counts were measured by drawing ROI on the phantom images and linearity was measured using background correction. Results: The prompt count rates in list mode were linearly increased proportionally to the activity concentration. At a low activity concentration (<30 kBq/mL), the prompt net true and random count rates were increased with the activity concentration. At a high activity concentration (>30 kBq/mL), the increasing rate of the prompt net true rates was slightly decreased while the increasing rate of random counts was increased. There was no difference in the image intensity linearity between OSEM and FBP algorithms. Conclusion: The Biograph 40 True Point PET/CT scanner showed good linearity of count rate even at a high activity concentration (~370 kBq/mL).The result indicates that the scanner is useful for the quantitative analysis of data in heart dynamic studies using Rb-82, N-13, O-15 and F-18.

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A Study on Pollution Conditions and Management of Sand Flooring Related to Animal Feces - Nitrogen Analysis Method Development - (동물 분변으로 인한 모래 바닥재의 오염실태 및 관리 방안에 관한 연구 - 질소분석방법개발 -)

  • Jeong, Won-Gu;Ha, Ji-Young;Oh, Geun-Chan;Huh, In-Ryang;Choi, Seung-Bong
    • Journal of Environmental Health Sciences
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    • v.46 no.6
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    • pp.646-654
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    • 2020
  • Objectives: Users of parks or children's play facilities have pointed to pets' bowel movements as the most serious problem when using them. In prior studies, a very low detection rate of parasites (eggs) in sand flooring materials has been found. Even though feces have been identified, no parasites (eggs) have been detected. Method: A standard solution of nitrate nitrogen was used to verify the reliability of a new nitrogen analysis method. The linearity, precision, and accuracy of the nitrate nitrogen analysis method were verified. Using this method, the pollution distribution of the sand flooring material and the degree of pollution at each point were investigated. Results: As a result of the verification of the nitrogen analysis method, the linearity was found to be good at r2=0.999 when distilled water is mixed in a standard substance solution. The standard substance additive solution r2=0.968 was found to be good. Precision represented 0.01 to 0.06% RSD for peak height. The recovery rate was 92.4 to 104.0 percent, indicating high accuracy. According to the same method of analysis, the flooring material sand at a general amusement facility with the largest number of concealed spaces was nitrate nitrogen 6.1 times higher than at the entrance of the playground. Also, in a comparison between clean sand and sandy flooring, the average nitrogen concentration of the sand flooring material was 24.4-167 times higher than pure sand. Conclusions: As such, no parasites (eggs) were detected at all points under investigation, but the sand flooring was exposed to animal fecal contamination. Therefore, the management of nitrogenous components should allow accurate identification of animal fecal contamination so that the timing of sand replacement can be managed hygienically and safely.

Analysis of Health-related Microbes by Capillary Electrophoresis

  • Moon, Byoung-Geoun;Kim, Yong-Seong
    • Bulletin of the Korean Chemical Society
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    • v.24 no.8
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    • pp.1203-1206
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    • 2003
  • Analysis of health-related microbes called probiotics was performed by capillary electrophoresis. A rapid and easy characterization for two important probiotics, Saccharomyces cerevisiae and Enterococcus feacalis, was obtained in the running buffer containing poly(ethylene oxide). Quantitation of probiotic (Saccharomyces cerevisiae) shows a good linearity between the peak area versus the concentration of microbe. From the comparison of electropherograms of antidiarrhea, it was found that capillary electrophoresis could be employed for the quality control and quality assurance for the production of a medicine containing the probiotics.

Shape Optimization for Magnetic Pole Piece of PM MRI using Nonlinear Parameterized Sensitivity Analysis (매개화된 민감도 해석에 의한 PM MRI의 Pole Piece 형상 최적화)

  • Ryu, Jae-Seop;Koh, Chang-Seop
    • Proceedings of the KIEE Conference
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    • 2004.10a
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    • pp.70-72
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    • 2004
  • The ferromagnetic pole piece of permanent magnet assembly for magnetic resonance imaging(MRI) is optimally designed to get high homogenious magnetic field, taking into account the non-linearity of the magnetic materials. In the design, the pole face is kept smooth and axis-symmetric by using B-spline parameterization, and nonlinear design sensitivity analysis is used for search direction.

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A study on the techniques of large scale chemical process system analysis (화학공정에 있어서의 대규모공정 해석방법)

  • 조인호;문장호;윤인섭
    • 제어로봇시스템학회:학술대회논문집
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    • 1986.10a
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    • pp.560-565
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    • 1986
  • For the control of chemical process, optimal value of the process should be known at first. And process simulation is the previous step of optimal value calculation. However it is not a simple work to analyze chemical process system. Especially for the large scale chemical process system, many difficulties such as non-linearity and complexity caused by recycle streams should be overcome. In this paper, three strategies of large scale chemical process analysis were explained and discussed with case studies.

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An Analytical Study on the Elasto-Plastic Behavior of Reinforced Concrete Structure under Monotonic & Cyclic Load (단조 증가 및 반복 하중을 받는 철근 콘크리트 구조물의 탄소성 거동에 대한 해석적 연구)

  • 김화중;박정민;마은희
    • Proceedings of the Computational Structural Engineering Institute Conference
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    • 1993.10a
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    • pp.131-138
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    • 1993
  • To analysis machanical behavior for RC frame under monotonic & Cyclic load, it is needed to investigate elasto-plastic behavior for steel & concrete. Therefore, in this study, we idealized material model(steel and concrete) to take into account elasto-plastic, limit state, and developed structural analysis program that consider complex non-linearity. We investigated simple beam and portal frame under cyclic & monotonic loading, so we confirmed the propriety.

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Finite Element Analysis of the Gangway of a Korea High Speed Train (한국형 고속전철 관절장치의 구조해석)

  • 노규석;이상록;강재윤
    • Proceedings of the KSR Conference
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    • 2001.05a
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    • pp.222-229
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    • 2001
  • This paper aims to verify the static strength of a KHST gangway structure including fixed ring and carrying ring according to tile load cases in the defined specification. The structure has been analyzed by the finite element method. Calculation carried out in tile fields of linearity and small deformation. The admissible limit is tile yield strength for the available materials. The analysis results show that Von-Mises stress at some locations of the structure is a little beyond the admissible limit. These results are successfully reflected on the adjusted design.

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Performance of a Compton Suppression Spectrometer of the SNU-KAERI PGAA Facility

  • Sun Gwang Min;Park Chang Su;Choi H.D.
    • Nuclear Engineering and Technology
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    • v.35 no.4
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    • pp.347-355
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    • 2003
  • The \gamma-ray spectrometer of the PGAA (Prompt Gamma Activation Analysis) facility constructed at HANARO of the Korea Atomic Energy Research Institute was upgraded to the multi-mode spectrometer including the single mode, the Compton suppression mode and the pair mode. The performance of the spectrometer was tested and summarized. The background count rate and the uncertainty of the detection efficiency were reduced greatly in comparison with those before the new installation.

Design, Linear and Efficient Analysis of Doherty Power Amplifier for IMT-2000 Base Station (IMT-2000 기지국용 도허티 전력증폭기의 설계 및 선형성과 효율 분석)

  • Kim Seon-Keun;Kim Ki-Moon
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.9 no.2
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    • pp.262-267
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    • 2005
  • During several method of improvement efficient, We analyzed Doherty Amplifier That used by simple circuit and 180w PEP LDMOS to analyze improvement of efficient and linearity. We for testing performance of Doherty Amplifier compared with Balanced Class AB, the experimental results show when Peaking Amp $V_gs.P$=1.53V, the efficiency is increased at Maximum 11.6$\%$. After finding optimum bias point of linearity improvement by manual tuning gate bias, when WCDMA 4FA $V_gs.P$=3.68V IMSR could be increased maximum 3.34dB. especially, when we match bias point of Peaking amp at 1.53V, we could get a excellent efficiency increase and have fUR under -3203c at output power 43dBm.

Experimental Investigation on the Non-linearity of Nitrile Butadiene Rubber (Nitrile Butadiene Rubber의 비선형성에 대한 실험적 연구)

  • Yoo, Myung-Ho;Lee, Taek-Sung;Do, Je-Sung;Kwon, Jong-Ho
    • Elastomers and Composites
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    • v.42 no.3
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    • pp.159-167
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    • 2007
  • Hydraulic actuators are used widely for industrial machinery. The seal made from elastomer is used as a core part of the actuator, NBR(nitrile butadiene rubber) materials with high quality of oil resistance and abrasion resistance is used widely, requiring excellent characteristic of sealing. According to applied circumstances, the actuators for industrial machinery are used under different temperature situations. In this study, three different kinds of NBR, which is Hs70, 80, 90 are determined as one of hydraulic materials. An experimental investigation is performed to confirm the non-linearity under different temperature ($-10^{\circ}C,\;20^{\circ}C,\;80^{\circ}C,\;100^{\circ}C$) situation, material constants for finite element analysis and plastic deformation in accordance with Load-unload.