• Title/Summary/Keyword: linear predictive

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Development and validation of prediction equations for the assessment of muscle or fat mass using anthropometric measurements, serum creatinine level, and lifestyle factors among Korean adults

  • Lee, Gyeongsil;Chang, Jooyoung;Hwang, Seung-sik;Son, Joung Sik;Park, Sang Min
    • Nutrition Research and Practice
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    • v.15 no.1
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    • pp.95-105
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    • 2021
  • BACKGROUND/OBJECTIVES: The measurement of body composition, including muscle and fat mass, remains challenging in large epidemiological studies due to time constraint and cost when using accurate modalities. Therefore, this study aimed to develop and validate prediction equations according to sex to measure lean body mass (LBM), appendicular skeletal muscle mass (ASM), and body fat mass (BFM) using anthropometric measurement, serum creatinine level, and lifestyle factors as independent variables and dual-energy X-ray absorptiometry as the reference method. SUBJECTS/METHODS: A sample of the Korean general adult population (men: 7,599; women: 10,009) from the Korean National Health and Nutrition Examination Survey 2008-2011 was included in this study. The participants were divided into the derivation and validation groups via a random number generator (with a ratio of 70:30). The prediction equations were developed using a series of multivariable linear regressions and validated using the Bland-Altman plot and intraclass correlation coefficient (ICC). RESULTS: The initial and practical equations that included age, height, weight, and waist circumference had a different predictive ability for LBM (men: R2 = 0.85, standard error of estimate [SEE] = 2.7 kg; women: R2 = 0.78, SEE = 2.2 kg), ASM (men: R2 = 0.81, SEE = 1.6 kg; women: R2 = 0.71, SEE = 1.2 kg), and BFM (men: R2 = 0.74, SEE = 2.7 kg; women: R2 = 0.83, SEE = 2.2 kg) according to sex. Compared with the first prediction equation, the addition of other factors, including serum creatinine level, physical activity, smoking status, and alcohol use, resulted in an R2 that is higher by 0.01 and SEE that is lower by 0.1. CONCLUSIONS: All equations had low bias, moderate agreement based on the Bland-Altman plot, and high ICC, and this result showed that these equations can be further applied to other epidemiologic studies.

Application of Predictive Microbiology for Microbiological Shelf Life Estimation of Fresh-cut Salad with Short-term Temperature Abuse (PMP 모델을 활용한 시판 Salad의 Short-term Temperature Abuse 시 미생물학적 유통기한 예측에의 적용성 검토)

  • Lim, Jeong-Ho;Park, Kee-Jea;Jeong, Jin-Woong;Kim, Hyun-Soo;Hwang, Tae-Young
    • Food Science and Preservation
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    • v.19 no.5
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    • pp.633-638
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    • 2012
  • The aim of this study was to investigate the growth of aerobic bacteria in fresh-cut salad during short-term temperature abuse ($4{\sim}30^{\circ}C$temperature for 1, 2, and 3 h) for 72 h and to develop predictive models for the growth of total viable cells (TVC) based on Predictive food microbiology (PFM). The tool that was used, Pathogen Modeling program (PMP 7.0), predicts the growth of Aeromonas hydrophila (broth Culture, aerobic) at pH 5.6, NaCl 2.5%, and sodium nitrite 150 ppm for 72 h. Linear models through linear regression analysis; DMFit program were created based on the results obtained at 5, 10, 20, and $30^{\circ}C$ for 72 h ($r^2$ >0.9). Secondary models for the growth rate and lag time, as a function of storage temperature, were developed using the polynomial model. The initial contamination level of fresh-cut salad was 5.6 log CFU/mL of TVC during 72 h storage, and the growth rate of TVC was shown to be 0.020~1.083 CFU/mL/h ($r^2$ >0.9). Also, the growth tendency of TVC was similar to that of PMP (grow rate: 0.017~0.235 CFU/mL/h; $r^2=0.994{\sim}1.000$). The predicted shelf life with PMP was 24.1~626.5 h, and the estimated shelf life of the fresh-cut salads with short-term temperature abuse was 15.6~31.1 h. The predicted shelf life was more than two times the observed one. This result indicates a 'fail safe' model. It can be taken to a ludicrous extreme by adopting a model that always predicts that a pathogenic microorganism will grow even under conditions so strict as to be actually impossible.

Linear Model Predictive Control of an Entrained-flow Gasifier for an IGCC Power Plant (석탄 가스화 복합 발전 플랜트의 분류층 가스화기 제어를 위한 선형 모델 예측 제어 기법)

  • Lee, Hyojin;Lee, Jay H.
    • Korean Chemical Engineering Research
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    • v.52 no.5
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    • pp.592-602
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    • 2014
  • In the Integrated Gasification Combined Cycle (IGCC), the stability of the gasifier has strong influences on the rest of the plant as it supplies the feed to the rest of the power generation system. In order to ensure a safe and stable operation of the entrained-flow gasifier and for protection of the gasifier wall from the high internal temperature, the solid slag layer thickness should be regulated tightly but its control is hampered by the lack of on-line measurement for it. In this study, a previously published dynamic simulation model of a Shell-type gasifier is reproduced and two different linear model predictive control strategies are simulated and compared for multivariable control of the entrained-flow gasifier. The first approach is to control a measured secondary variable as a surrogate to the unmeasured slag thickness. The control results of this approach depended strongly on the unmeasured disturbance type. In other words, the slag thickness could not be controlled tightly for a certain type of unmeasured disturbance. The second approach is to estimate the unmeasured slag thickness through the Kalman filter and to use the estimate to predict and control the slag thickness directly. Using the second approach, the slag thickness could be controlled well regardless of the type of unmeasured disturbances.

Performance Improvement of Speaker Recognition by MCE-based Score Combination of Multiple Feature Parameters (MCE기반의 다중 특징 파라미터 스코어의 결합을 통한 화자인식 성능 향상)

  • Kang, Ji Hoon;Kim, Bo Ram;Kim, Kyu Young;Lee, Sang Hoon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.6
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    • pp.679-686
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    • 2020
  • In this thesis, an enhanced method for the feature extraction of vocal source signals and score combination using an MCE-Based weight estimation of the score of multiple feature vectors are proposed for the performance improvement of speaker recognition systems. The proposed feature vector is composed of perceptual linear predictive cepstral coefficients, skewness, and kurtosis extracted with lowpass filtered glottal flow signals to eliminate the flat spectrum region, which is a meaningless information section. The proposed feature was used to improve the conventional speaker recognition system utilizing the mel-frequency cepstral coefficients and the perceptual linear predictive cepstral coefficients extracted with the speech signals and Gaussian mixture models. In addition, to increase the reliability of the estimated scores, instead of estimating the weight using the probability distribution of the convectional score, the scores evaluated by the conventional vocal tract, and the proposed feature are fused by the MCE-Based score combination method to find the optimal speaker. The experimental results showed that the proposed feature vectors contained valid information to recognize the speaker. In addition, when speaker recognition is performed by combining the MCE-based multiple feature parameter scores, the recognition system outperformed the conventional one, particularly in low Gaussian mixture cases.

Influences of Emotional Labor, Hardiness on Job Satisfaction of Nurses in Comprehensive Nursing Care Service Units (간호·간병통합서비스 병동 간호사의 감정노동, 강인성이 직무만족도에 미치는 영향)

  • Lim, Hye-Sook;Song, Eun Ju
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.4
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    • pp.65-72
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    • 2020
  • The purpose of this descriptive research study was to identify the effects on job satisfaction of nurses working at comprehensive nursing care service units. The study was conducted in five hospitals, two of 250 beds or more in three cities and three of 800 beds. The study subjects were nurses working at comprehensive nursing care service units. A structured questionnaire of 150 questions was distributed to them and 146 were collected. The data collection period was from August 1, 2019 to November 15, 2019. The collected data were analyzed using the SPSS 22.0 program, using x2-test, t-test, ANOVA, Pearson correlation, and multiple linear regression. Emotional labor and toughness were negatively correlated (r=-.20, p=.018), and emotional labor and job satisfaction were positively correlated (r=.25, p=.004). The predictive variables affecting the job satisfaction of the subjects were the aptitude of the ward service (β=-.35, p=<.001) and hardness(β=.21, p=.009). The explanation of job satisfaction in the variables was 18.2% (F=3.54, p=.009). The study results revealed that the predictive variables affecting job satisfaction were the hardiness and aptitude of the ward service. Therefore, in order to increase the job satisfaction of ward nurses, it is necessary to provide administrative support to control the hardiness of the nurse and to allocate manpower in consideration of the aptitude in the hospital personnel system.

A Study on the Performance Degradation Pattern of Caisson-type Quay Wall Port Facilities (케이슨식 안벽 항만시설의 성능저하패턴 연구)

  • Na, Yong Hyoun;Park, Mi Yeon;Jang, Shinwoo
    • Journal of the Society of Disaster Information
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    • v.18 no.1
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    • pp.146-153
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    • 2022
  • Purpose: In the case of domestic port facilities, port structures that have been in use for a long time have many problems in terms of safety performance and functionality due to the enlargement of ships, increased frequency of use, and the effects of natural disasters due to climate change. A big data analysis method was studied to develop an approximate model that can predict the aging pattern of a port facility based on the maintenance history data of the port facility. Method: In this study, member-level maintenance history data for caisson-type quay walls were collected, defined as big data, and based on the data, a predictive approximation model was derived to estimate the aging pattern and deterioration of the facility at the project level. A state-based aging pattern prediction model generated through Gaussian process (GP) and linear interpolation (SLPT) techniques was proposed, and models suitable for big data utilization were compared and proposed through validation. Result: As a result of examining the suitability of the proposed method, the SLPT method has RMSE of 0.9215 and 0.0648, and the predictive model applied with the SLPT method is considered suitable. Conclusion: Through this study, it is expected that the study of predicting performance degradation of big data-based facilities will become an important system in decision-making regarding maintenance.

A Comparison of Predicting Movie Success between Artificial Neural Network and Decision Tree (기계학습 기반의 영화흥행예측 방법 비교: 인공신경망과 의사결정나무를 중심으로)

  • Kwon, Shin-Hye;Park, Kyung-Woo;Chang, Byeng-Hee
    • Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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    • v.7 no.4
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    • pp.593-601
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    • 2017
  • In this paper, we constructed the model of production/investment, distribution, and screening by using variables that can be considered at each stage according to the value chain stage of the movie industry. To increase the predictive power of the model, a regression analysis was used to derive meaningful variables. Based on the given variables, we compared the difference in predictive power between the artificial neural network, which is a machine learning analysis method, and the decision tree analysis method. As a result, the accuracy of artificial neural network was higher than that of decision trees when all variables were added in production/ investment model and distribution model. However, decision trees were more accurate when selected variables were applied according to regression analysis results. In the screening model, the accuracy of the artificial neural network was higher than the accuracy of the decision tree regardless of whether the regression analysis result was reflected or not. This paper has an implication which we tried to improve the performance of movie prediction model by using machine learning analysis. In addition, we tried to overcome a limitation of linear approach by reflecting the results of regression analysis to ANN and decision tree model.

Development of the Predicted Model for the HMA Dynamic Modulus by using the Impact Resonance Testing and Universal Testing Machine (충격공진실험과 만능재료시험기에 의한 아스팔트 공시체의 동탄성계수 예측 모델 개발)

  • Kim, Do Wan;Kim, Dong-Ho;Mun, Sungho
    • International Journal of Highway Engineering
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    • v.16 no.3
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    • pp.43-50
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    • 2014
  • PURPOSES : The dynamic modulus can be determined by applying the various theories from the Impact Resonance Testing(IRT) Method. The objective of this paper is to determine the best theory to produce the dynamic modulus that has the lowest error as the dynamic modulus data obtained from these theories(Complex Wave equation Resonance Method related to either the transmissibility loss or not, Dynamic Stiffness Resonance Method) compared to the results for dynamic modulus determined by using the Universal Testing Machine. The ultimate object is to develop the predictive model for the dynamic modulus of a Linear Visco-Elastic specimen by using the Complex Wave equation Resonance Method(CWRM) came up for an existing study(S. O. Oyadiji; 1985) and the Optimization. METHODS : At the destructive test which uses the Universal Testing Machine, the dynamic modulus results along with the frequency can be used for determining the sigmoidal master curve function related to the reduced frequency by applying Time-Temperature Superposition Principle. RESULTS : The constant to be solved from Eq. (11) is a value of 14.13. The reduced dynamic modulus obtained from the IRT considering the loss factor related to the impact transmissibility has RMSE of 367.7MPa, MPE of 3.7%. When the predictive dynamic modulus model was applied to determine the master curve, the predictive model has RMSE of 583.5MPa, MPE of 3.5% compared to the destructive test results for the dynamic modulus. CONCLUSIONS : Because we considered that the results obtained from the destructive test had the most highest source credibility in this study, the dynamic modulus data obtained respectively from DSRM, CWRM were compared to the results obtained from the destructive test by using th IRT. At the result, the reduced dynamic modulus derived from DSRM has the most lowest error.

A predictive model to guide management of the overlap region between target volume and organs at risk in prostate cancer volumetric modulated arc therapy

  • Mattes, Malcolm D.;Lee, Jennifer C.;Elnaiem, Sara;Guirguis, Adel;Ikoro, N.C.;Ashamalla, Hani
    • Radiation Oncology Journal
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    • v.32 no.1
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    • pp.23-30
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    • 2014
  • Purpose: The goal of this study is to determine whether the magnitude of overlap between planning target volume (PTV) and rectum ($Rectum_{overlap}$) or PTV and bladder ($Bladder_{overlap}$) in prostate cancer volumetric-modulated arc therapy (VMAT) is predictive of the dose-volume relationships achieved after optimization, and to identify predictive equations and cutoff values using these overlap volumes beyond which the Quantitative Analyses of Normal Tissue Effects in the Clinic (QUANTEC) dose-volume constraints are unlikely to be met. Materials and Methods: Fifty-seven patients with prostate cancer underwent VMAT planning using identical optimization conditions and normalization. The PTV (for the 50.4 Gy primary plan and 30.6 Gy boost plan) included 5 to 10 mm margins around the prostate and seminal vesicles. Pearson correlations, linear regression analyses, and receiver operating characteristic (ROC) curves were used to correlate the percentage overlap with dose-volume parameters. Results: The percentage $Rectum_{overlap}$ and $Bladder_{overlap}$ correlated with sparing of that organ but minimally impacted other dose-volume parameters, predicted the primary plan rectum $V_{45}$ and bladder $V_{50}$ with $R^2$ = 0.78 and $R^2$ = 0.83, respectively, and predicted the boost plan rectum $V_{30}$ and bladder $V_{30}$ with $R^2$ = 0.53 and $R^2$ = 0.81, respectively. The optimal cutoff value of boost $Rectum_{overlap}$ to predict rectum $V_{75}$ >15% was 3.5% (sensitivity 100%, specificity 94%, p < 0.01), and the optimal cutoff value of boost $Bladder_{overlap}$ to predict bladder $V_{80}$ >10% was 5.0% (sensitivity 83%, specificity 100%, p < 0.01). Conclusion: The degree of overlap between PTV and bladder or rectum can be used to accurately guide physicians on the use of interventions to limit the extent of the overlap region prior to optimization.

Verification of Cardiac Electrophysiological Features as a Predictive Indicator of Drug-Induced Torsades de pointes (약물의 염전성 부정맥 유발 예측 지표로서 심장의 전기생리학적 특징 값들의 검증)

  • Yoo, Yedam;Jeong, Da Un;Marcellinus, Aroli;Lim, Ki Moo
    • Journal of Biomedical Engineering Research
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    • v.43 no.1
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    • pp.19-26
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    • 2022
  • The Comprehensive in vitro Proarrhythmic Assay(CiPA) project was launched for solving the hERG assay problem of being classified as high-risk groups even though they are low-risk drugs due to their high sensitivity. CiPA presented a protocol to predict drug toxicity using physiological data calculated based on the in-silico model. in this study, features calculated through the in-silico model are analyzed for correlation of changing action potential in the near future, and features are verified through predictive performance according to drug datasets. Using the O'Hara Rudy model modified by Dutta et al., Pearson correlation analysis was performed between 13 features(dVm/dtmax, APpeak, APresting, APD90, APD50, APDtri, Capeak, Caresting, CaD90, CaD50, CaDtri, qNet, qInward) calculated at 100 pacing, and between dVm/dtmax_repol calculated at 1,000 pacing, and linear regression analysis was performed on each of the 12 training drugs, 16 verification drugs, and 28 drugs. Indicators showing high coefficient of determination(R2) in the training drug dataset were qNet 0.93, AP resting 0.83, APDtri 0.78, Ca resting 0.76, dVm/dtmax 0.63, and APD90 0.61. The indicators showing high determinants in the validated drug dataset were APDtri 0.94, APD90 0.92, APD50 0.85, CaD50 0.84, qNet 0.76, and CaD90 0.64. Indicators with high coefficients of determination for all 28 drugs are qNet 0.78, APD90 0.74, and qInward 0.59. The indicators vary in predictive performance depending on the drug dataset, and qNet showed the same high performance of 0.7 or more on the training drug dataset, the verified drug dataset, and the entire drug dataset.