• 보건교육건강증진학회지
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• 제28권2호
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• pp.51-62
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• 2011

Objectives: The aim of the study was to identify the effects of a community-level metabolic syndrome self-care management program. Methods: Data included baseline demographics, abdominal circumference, blood pressure, blood sugar, triglyceride, and HDL-cholesterol collected at 15 public health centers in Seoul from January to March, 2010. A data obtained(584 men and 410 women) from Metabolic Syndrome Management Program in Seoul was analyzed using Paired t-test and Linear mixed model. Results: The group with 6-month intervention resulted in significant decrease in abdominal circumference, systolic and diastolic blood pressure, blood sugar, and triglyceride. In moderate intervention group with 3-month follow-up showed tendency that abdominal circumference(-1.27(${\beta}$)) and diastolic blood pressure(-1.66(${\beta}$)) are significantly reduced. In the group with aggressive intervention, the more counseling led to significant reduction in abdominal circumference(-0.22(${\beta}$)). Conclusions: These results indicate that a self-care for metabolic syndrome management can improve metabolic syndrome status over a short-term period. Further structured research is needed to develop a systematic program on health behaviors focusing on exercise, diet, and intervention.

• Journal of Acupuncture Research
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• 제29권5호
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• pp.1-16
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• 2012

Objectives : The purpose of this study was to examine the effects of manual acupuncture at the $LI_4$, $ST_{36}$ and $LR_3$ on Electroencephalogram(EEG) of patients with stroke. Methods : 32 channel EEG measurement was carried out in 35 Stroke patients(23 males and 12 females). EEG was measured for 21 minutes(made up of 7 sessions, 1 session means 3 minutes time interval) including 15 minutes(5 sessions) of acupuncture time. Power spectrum analysis was used as a measure of complexity. Statistical analysis was performed using Linear mixed model and DUNNETT's multiple comparison. Results : The results were as follows; 1. EEG amplitude was reduced during acupuncture except electrodes PG1 and PG2. 2. There was a notable change during 6~9 minutes after needling in ${\delta}{\cdot}{\beta}{\cdot}{\gamma}$ wave, and during 6~9 minutes after needling in ${\Theta}{\cdot}{\alpha}$ wave. Overall, during 6~9 minutes after needling. 3. TP8 is a common significant electrode among five wave forms. Conclusions : These results suggest that TP8 could be typical electrodes and change of EEG compared to baseline happens most often during 6~9 minutes after manipulated acupuncture at the $LI_4$, $ST_{36}$ and $LR_3$ of patients with stroke.

• Asian-Australasian Journal of Animal Sciences
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• 제23권6호
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• pp.814-824
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• 2010

The objective of this research was to assess the effect of experience, education, record keeping, labor, and decision making on monthly milk yield per farm (MYF), monthly milk yield per cow (MYC), monthly milk revenue per farm (MRF), and monthly revenue per cow (MRC) of dairy farms supported by a private organization in Central Thailand. The dataset contained 34,082 monthly milk yield and revenue records collected from January 2004 to December 2008 on 497 farms, and information on individual farmer experience and education, record keeping, and decision making obtained with a questionnaire. Farmer experience categories were i) no experience, ii) one year, iii) two to five years, iv) six to ten years, v) eleven to fifteen years, vi) sixteen to twenty years, and vii) more than twenty years. Farmer education categories were i) no education or primary school, ii) high school, and iii) bachelor or higher degree. Record keeping categories were: i) no records and ii) kept records. Labor categories were: i) family, ii) hired people, and iii) family and hired people. Decision making categories were: i) decisions made by farmers themselves, ii) decisions made with help from government officials, and iii) decisions made with help from organization staff. The mixed linear model contained the fixed effects of year-season, farm location-farm size subclass, experience, education, record keeping, labor, and decision making on sire selection, and the random effects of farm and residual. Results showed that longer experience increased (p<0.05) monthly milk yield (MYF and MYC) and revenue (MRF and MRC). Farms that hired people produced the highest (p<0.05) monthly milk yield (MYF and MYC) and revenue (MRF and MRC), followed by farms that used family, and the lowest values were for farms that used both family and hired people. Better educated farmers produced more MYC and MRC (p<0.05) than lower educated farmers. Farms that kept records had higher MYF and MRF (p<0.05) than those without records. Although differences among farms were non-significant, farms that received help from the organization staff had higher monthly milk yield (MYF and MYC) and revenue (MRF and MRC) than those that decided by themselves or with help from government officials. These findings suggested that dairy farmers needed systematic training and continuous support to improve farm milk production and revenues in a sustainable manner.

• Asian-Australasian Journal of Animal Sciences
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• 제33권11호
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• pp.1755-1762
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• 2020

Objective: Thyroid hormone responsive spot 14 alpha (THRSP) has been used to investigate the regulation of de novo lipogenesis because the variation of THRSP mRNA content in the tissue affects directly the ability of that tissue to synthetize lipids. Also, this gene responds to thyroid hormone stimulation and high level of carbohydrate feeding or insulin-injection. This study was carried out to investigate variations within THRSP and their effects on body and carcass weights in Korean native chicken (KNC). Methods: A total of 585 chickens which represent the five lines of KNC (Black, Gray-Brown, Red-Brown, White, and Yellow-Brown) were reared and body weight data were recorded every two weeks from hatch until 20 weeks of age. Polymerase chain reaction- restriction fragment length polymorphism, DNA chips for Agilent 2100 Bioanalyzer, and Fluidigm Genotyping Technology, were applied to genotype selected markers. A linear mixed-effect model was used to access association between these single nucleotide polymorphism (SNP) markers and growth-related traits. Results: A total of 30 polymorphisms were investigated in THRSP. Of these, nine SNPs for loci were selected to perform association analyses. Significant associations were detected between g.-49G>T SNP with body weight at 20 weeks of age (BW20), g.451T>C SNP with growth at 10 to 12 weeks of age (GR10-12), and g.1432A>C SNP with growth at 14 to 16 weeks trait (GR14-16) and body weight at 18 weeks of age (BW18). Moreover, diplotype of the THRSP gene significantly affected body weight at 12 weeks of age (BW12) and GR10-12 traits. Diplotype of ht1/ht2 was favorable for BW12 and GR10-12 traits. Conclusion: These results suggest that THRSP can be regarded as a candidate gene for growth traits in KNC.

• 노인정신의학
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• 제21권1호
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• pp.35-40
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• 2017

Objective : This study aimed to investigate the effect of community-based Goal-Achieving program in geriatric depressive symptoms preliminarily. Methods : We obtained data from elderly Korean subjects with major depressive disorder (n=51) aged 60 years or older at baseline, taking case management from community mental health center. Subjects were randomly assigned to intervention group (n=24) and control group (n=27). We investigated depressive symptoms through Short Form Geriatric Depression Scale-Korean version (SGDS-K) at baseline and every month for 3 months to all subjects. We tested interaction between group and time in SGDS-K score to evaluate the effect of program. And post hoc test examined between group differences of SGDS-K at each time points. Results : In quadratic linear mixed effects model analysis, interaction between group and time was statistically significant (Total SGDS-K score : coefficient=0.29, p<0.001 ; SGDS-K dysphoria subscale : 0.18, p<0.001 ; SGDS-K hopelessness subscale : 0.05, p=0.089 ; SGDS-K cognitive impairment subscale : 0.06, p=0.003). And significant between group difference was shown in post hoc test at time points of third month (SGDS-K score of control group : SGDS-K score of intervention group=$10.74{\pm}3.482$ : $7.25{\pm}4.475$, p=0.0184). Conclusion : These results may suggest that 'Community-based the Goal-Achieving program' has efficacy in reducing geriatric depressive symptoms.

• 한국전문물리치료학회지
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• 제29권2호
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• pp.117-123
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• 2022

Background: Push-up are effective exercises for shoulder stability. Previous studies have documented the effects of support plane and hand position and width on muscle activities during a push-up. Objects: This study aimed to investigate the changes in muscle activities in the upper extremity when performing the standard and the knee-flexed push-up with different hand shapes. Methods: A total of twenty-six healthy males participated in this study. Three different hand shapes (finger abduction, finger adduction, and fists) and two types of push-up posture (standard and knee-flexed push-up) were set as the independent variables. Electrograms were used to measure the muscle activity of the upper trapezius (UT), triceps brachii (TB), pectoralis major (PM), and serratus anterior (SA). Each participant performed the randomly assigned push-up to the sound of the metronome. The mixed-effect linear regression model was used to detect the changes in muscle activities after changing the hand shape and push-up posture. Statistical significance was set at α = 0.05. Results: The UT muscle activity was statistically significantly higher when performing push-up with fists than finger abduction (p = 0.035) or finger adduction (p = 0.044). During the standard push-up, the muscle activity in all muscles was that the push-up with fists showed the highest muscle activity compared to the finger abduction (p < 0.01) and finger adduction (p < 0.01). Regardless of the shape of the hand, UT had the lowest muscle activity compared to other muscles (p < 0.001). In contrast, the SA muscle had the highest muscle activity among four muscles during the standard push-up. Conclusion: Based on the results of this study, we suggest hand shape is related to the difficulty level of push-up either in the standard or the knee-flexed push-up, especially in the push-up with fists. In addition, knee push-up can be recommended as shoulder muscle-strengthening exercises for individuals with low shoulder muscle strength.

• 수면정신생리
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• 제13권2호
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• pp.67-74
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• 2006

서 론：기면병은 과도한 주간졸림증과 탈력발작을 주 증상으로 하는 질환이다. 모다피닐은 기면병 치료에 이용되는 정신자극제이다. 본 연구에서는 모다피닐이 기면병환자와 정산인의 임상 양상과 야간수면구조 및 주간 졸음증에 미치는 영향을 평가하였다. 방 법：기면병 환자 12명(연령：$22.9{\pm}2.6$세)(남：여=7：5)과 성별, 연령이 짝지어진 대조군 12명($23.8{\pm}2.5$세)이 기저 연구(baseline study)에 참여하였다. 모든 참가자들을 기저검사로 임상 척도, 야간수면다원검사 및 주간입면시간반복검사를 시행하였으며, 모다피닐 200 밀리그램 투약 후 동일한 검사를 반복 시행하였다. 모다피닐 투여 이후 임상척도, 야간수면다원검사 및 주간입면시간반복검사 수면관련변인의 변화를 비교하였다. 결 과：모다피닐 투여는 피츠버그수면장애척도 점수만을 감소시켰을 뿐 그 외의 임상적 척도에는 영향을 주지 않았다. 본 연구에서 기면병 환자와 대조군에서, 투약 전에 비하여 투약 후 야간수면다원검사의 총수면 시간, 수면 효율이 감소하였고, 입면 후 각성 시간과 총검사시간 중 각성 시간의 비율은 증가하였다. 이어서 시행한 주간입면시간반복검사상 평균입면잠복시간이 연장되는 소견을 보였다. 결 론：모다피닐은 각성 효과를 지닌 약물로 메틸페니데이트 등 기존 투약에 비해 야간수면에 대한 영향이 적은 약물이다. 본 연구에서 총수면 시간, 수면 효율 및 각성 시간의 비율 증가를 보여 야간수면에 영향을 주지만 수면구조 전체에는 영향을 주지 않았다. 모다피닐의 효과를 평가하기 위해 시행된 주간입면시간반복검사 상 평균입면잠복기의 연장을 보여 기면병과 관련된 졸음 증상 조절에 효과적임을 확인할 수 있었다. 모다피닐은 주간졸림증이 없는 대조군에서도 각성도를 높이는 것으로 확인되었다.

• 생명과학회지
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• 제28권7호
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• pp.795-801
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• 2018

본 연구는 제주마 체중 형질과 말의 3번 및 9번 염색체 단일염기변이마커간의 관련성을 분석하기 위해 수행되었다. 본 연구에 사용된 DNA 샘플은 제주특별자치도 축산진흥원에서 등록관리 중인 제주마 320두를 제공받았고, 생체중 자료는 한국마사회에서 시행한 경마에 출주한 제주마의 체중자료를 이용하였다. 기존에 말의 체형관련형질과의관련성이 보고된 바 있는 말의 3번 염색체상에 위치한 BIEC2-808466, BIEC2-808543, BIEC2-808967, BIEC2-809370 단일염기변이마커와 9번 염색체상에 위치한 BIEC2-1105370, BIEC2-1105372, BIEC2-1105377, BIEC2-1105505 and BIEC2-1105840 유전자형을 분석하였다. 관련성 분석을 위한 종속변수는 선형혼합모형을 이용해서 추정한 생체중 육종가를 이용하였다. 관련성 분석결과 6개의 마커(BIEC2-808543, BIEC2-808967, BIEC2-809370, BIEC2-1105370, BIEC2-1105372, and BIEC2-1105377)와 생체중 추정육종가간의 유의성이 인정되었다. 또한, BIEC2-808967과 BIEC2-1105377의 유전자형조합을 구성하여 생체중 추정육종가에 대한 효과를 분석한 결과, 두 마커의 유전자 조합은 생체중 변이에 유의한 효과가 있었다. 본 연구에서 유의성이 인정된 단일염기변이마커들은 제주마의 체중 개량을 위한 선발육종체계의 효율성을 높일 수 있는데 사용될 수 있을 것으로 사료되지만, 이 들 마커효과의 좀더 정확한 추정을 위한 추가의 연구가 필요할 것으로 생각된다.