• Korean Chemical Engineering Research
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• v.46 no.4
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• pp.681-685
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• 2008

Chiral separation of racemic mandelic acid was achieved on a Kromasil KR100-5CHI-TBB column. Some chromatographic parameters (resolution, number of theoretical plates, capacity factor) are calculated under different separation conditions such as changes of mobile phase compositions (hexane/t-BME = 85/15 - 10/90) as well as formic acid concentrations for adjusting pH (0.1, 0.5, 1.0 v/v%). Flow rate versus number of theoretical plates was compared to evaluate column efficiency. To determine the adsorption isotherms, PIM (Pulse Input Method) was carried out. At the concentrations of racemic mandelic acid between 0.1 and 0.3 mg/ml, L- and D-mandelic acids have the same retention times of 8.8 and 9.4 min respectively. Mandelic acid isotherms show a linear form under the concentrations of 0.3 mg/ml with eluent (hexane/t-BME = 75/25). As the concentrations of mandelic acids increase, nonlinear Langmuir isotherms were observed as $C_{S,L}=3.358C_{M,L}/(1+0.0897C_{M,L})$ for L-mandelic acid and, $C_{S,D}=3.692C_{M,D}/(1+0.1457C_{M,D})$ for D-mandelic acid.

• The Transactions of the Korea Information Processing Society
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• v.13 no.6
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• pp.260-268
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• 2024

Cervical cancer is the fourth most common cancer in women worldwide, and more than 604,000 new cases were reported in 2020 alone, resulting in approximately 341,831 deaths. The Cox regression model is a major model widely adopted in cancer research, but considering the existence of nonlinear associations, it faces limitations due to linear assumptions. To address this problem, this paper proposes ResSurvNet, a new model that improves the accuracy of cervical cancer mortality prediction using ResNet's residual learning framework. This model showed accuracy that outperforms the DNN, CPH, CoxLasso, Cox Gradient Boost, and RSF models compared in this study. As this model showed accuracy that outperformed the DNN, CPH, CoxLasso, Cox Gradient Boost, and RSF models compared in this study, this excellent predictive performance demonstrates great value in early diagnosis and treatment strategy establishment in the management of cervical cancer patients and represents significant progress in the field of survival analysis.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.33 no.1
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• pp.31-43
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• 2015

This study had been aimed to conduct the camera calibration on VLBI antenna in the Space Geodetic Observation Center of Sejong City with a low-cost digital camera, which embedded in a mobile phone to determine the three-dimension position coordinates of the VLBI antenna, based on stereo images. The initial values for the camera calibration have been obtained by utilizing the Direct Linear Transformation algorithm and the commercial digital photogrammetry system, PhotoModeler $Scanner^{(R)}$ ver. 6.0, respectively. The accuracy of camera calibration results was compared with that the camera calibration results, acquired by a bundle adjustment with nonlinear collinearity condition equation. Although two methods showed significant differences in the initial value, the final calibration demonstrated the consistent results whichever methods had been performed for obtaining the initial value. Furthermore, those three-dimensional coordinates of feature points of the VLBI antenna were respectively calculated using the camera calibration by the two methods to be compared with the reference coordinates obtained from a total station. In fact, both methods have resulted out a same standard deviation of $X=0.004{\pm}0.010m$, $Y=0.001{\pm}0.015m$, $Z=0.009{\pm}0.017m$, that of showing a high degree of accuracy in centimeters. From the result, we can conclude that a mobile phone camera opens up the way for a variety of image processing studies, such as 3D reconstruction from images captured.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.44 no.9
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• pp.54-62
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• 2007

In this paper, a novel wideband notched compact UWB antenna is designed to satisfy the licensed UWB frequency bandwidth($3.1{\sim}4.8$ GHz, $7.1{\sim}10.2$ GHz) by symmetrically arranging two adjacent sectorial loop antennas. The wideband($4.8{\sim}7.1$ GHz) notch can be obtained by inserting the inverted-L shaped slits on the patch. The designed UWB antenna has return loss lower than -10dB at 3.1 GHz and over, group delay value lower than 1 ns and the linear phase property. The optimized UWB antenna inserted the inverted-L shaped slits has return loss great than -10dB, 5 ns of group delay, nonlinear phase and decreased gain properties over the frequency band, 4.8 GHz to 7.1 GHz.

• Korean Journal of Ecology and Environment
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• v.39 no.1 s.115
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• pp.52-61
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• 2006

The aim of this study was to analyze the seasonal patterns of zooplankton community dynamics in the lower Nakdong River (Mulgum, RK; river kilometer; 27 km from the estuarine barrage), with a Self-Organizing Map (SOM) based on weekly sampled data collected over ten years(1994 ${\sim}$ 2003). It is well known that zooplankton groups had important role in the food web of freshwater ecosystems, however, less attention has been paid to this group compared with other community constituents. A non-linear patterning algorithm of the SOM was applied to discover the relationship among river environments and zooplankton community dynamics. Limnological variables (water temperature, dissolved oxygen, pH , Secchi transparency, turbidity, chlorophyll a, discharge, etc.) were taken into account to implement patterning seasonal changes of zooplankton community structures (consisting of rotifers, cladocerans and copepods). The trained SOM model allocated zooplankton on the map plane with limnological parameters. Three zooplankton groups had high similarities to one another in their changing seasonal patterns, Among the limnological variables, water temporature was highly related to the zooplankton community dynamics (especially for cladocerans). The SOM model illustrated the suppression of zooplankton due to the increased river discharge, particularly in summer. Chlorophyll a concentrations were separated from zooplankton data set on the map plane, which would intimate the herbivorous activity of dominant grazers. This study introduces the zooplankton dynamics associated with limnological parameters using a nonlinear method, and the information will be useful for managing the river ecosystem, with respect to the food web interactions.

• Bulletin of the Korean Chemical Society
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• v.34 no.12
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• pp.3795-3799
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• 2013

The second-order rate constants ($k_N$) have been measured spectrophotometrically for nucleophilic substitution reactions of Y-substituted-phenyl 2-methylbenzoates (6a-e) with a series of cyclic secondary amines in MeCN at $25.0{\pm}0.1^{\circ}C$. Comparison of the $k_N$ values for the reactions of 4-nitrophenyl 2-methylbenzoate (6d) with those reported previously for the corresponding reactions of 4-nitrophenyl 2-methoxybenzoate (5) reveals that 6d is significantly less reactive than 5, indicating that modification of 2-MeO in the benzoyl moiety of 5 by 2-Me (i.e., $5{\rightarrow}6d$) causes a significant decrease in reactivity. This supports our previous report that aminolysis of 5 proceeds through a six-membered cyclic intermediate, which is highly stabilized through intramolecular H-bonding interactions. The Br${\o}$nsted-type plot for the reactions of 6d with a series of cyclic secondary amines is linear with ${\beta}_{nuc}=0.71$, which appears to be a lower limit of ${\beta}_{nuc}$ for a stepwise mechanism with breakdown of an intermediate ($T^{\pm}$) being rate-determining step (RDS). The Br${\o}$nsted-type plot for the reactions of 6a-e with piperidine is curved, i.e., the slope of Br${\o}$nsted-type plot (${\beta}_{lg}$) decreases from -1.05 to -0.41 as the leaving-group basicity decreases. The nonlinear Br${\o}$nsted-type plot has been taken as evidence for a stepwise mechanism with a change in RDS (e.g., from the $k_2$ step to the $k_1$ process as the leaving-group basicity decreases). Dissection of $k_N$ into the microscopic rate constants associated with the reactions of 6a-e with piperidine (e.g., $k_1$ and $k_2/k_{-1}$ ratio) also supports the proposed mechanism.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.19 no.2 s.72
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• pp.171-185
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• 2006

A sophisticated reliability analysis method is proposed to evaluate the reliability of real nonlinear complicated dynamic structural systems excited by short duration dynamic loadings like earthquake motions by intelligently integrating the response surface method, the finite element method, the first-order reliability method, and the iterative linear interpolation scheme. The method explicitly considers all major sources of nonlinearity and uncertainty in the load and resistance-related random variables. The unique feature of the technique is that the seismic loading is applied in the time domain, providing an alternative to the classical random vibration approach. The four-parameter Richard model is used to represent the flexibility of connections of real steel frames. Uncertainties in the Richard parameters are also incorporated in the algorithm. The laterally flexible steel frame is then reinforced with reinforced concrete shear walls. The stiffness degradation of shear walls after cracking is also considered. The applicability of the method to estimate the reliability of real structures is demonstrated by considering three examples; a laterally flexible steel frame with fully restrained connections, the same steel frame with partially restrained connections with different rigidities, and a steel frame reinforced with concrete shear walls.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.37 no.1
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• pp.29-41
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• 2017

Design rainfalls are one of the most important hydrologic data for river management, hydraulic structure design and risk analysis. The design rainfalls are first estimated by a point frequency analysis and the IDF (intensity-duration-frequency) curve is then constructed by a nonlinear regression to either interpolate or extrapolate the design rainfalls for other durations which are not used in the frequency analysis. It has been widely recognised that the more reliable approaches are required to better account for uncertainties associated with the model parameters under circumstances where limited hydrologic data are available for the watershed of interest. For these reasons, this study developed a hierarchical Bayesian based GLM (generalized linear model) for a regional frequency analysis in conjunction with a scaling function of the parameters in probability distribution. The proposed model provided a reliable estimation of a set of parameters for each individual station, as well as offered a regional estimate of the parameters, which allow us to have a regional IDF curve. Overall, we expected the proposed model can be used for different aspects of water resources planning at various stages and in addition for the ungaged basin.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.39 no.9
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• pp.929-936
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• 2015

Nacelle anemometers are mounted on wind-turbine nacelles behind blade roots to measure the free-stream wind speed projected onto the wind turbine for control purposes. However, nacelle anemometers measure the transformed wind speed that is due to the wake effect caused by the blades' rotation and the nacelle geometry, etc. In this paper, we derive the Nacelle Transfer Function (NTF) to calibrate the nacelle wind speed to the free-stream wind speed, as required to carry out the performance test of wind turbines according to the IEC 61400-12-2 Wind-Turbine Standard. For the reference free-stream wind data, we use the Light Detection And Ranging (LiDAR) measurement at the Shinan wind power plant located on the Bigeumdo Island shoreline. To improve the simple linear regression NTF, we derive the multiple nonlinear regression NTF. The standard error of the wind speed was found to have decreased by a factor of 9.4, whereas the mean of the power-output residual distribution decreased by 6.5 when the 2-parameter NTF was used instead of the 1-parameter NTF.

• Journal of the Korean Geosynthetics Society
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• v.14 no.1
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• pp.1-10
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• 2015

Recently, several researches on the development of new economical anchor systems have been performed to support floating structures. This study focused on the group suction piles, which connect mid-sized suction piles instead of a single suction pile with large-diameter. The group suction pile shows the complex bearing behavior with translation and rotation, so it is difficult to apply conventional design methods. Therefore, the numerical modeling technique was developed to evaluate the horizontal bearing capacity of the group suction piles in clay. The technique models suction piles as beam elements and soil reaction as non-linear springs. To analyze the applicability of the modeling, the horizontal load-movement curves of the proposed modeling were compared with those of three-dimensional finite element analyses. The comparison showed that the modeling underestimates the capacity and overestimate the displacement corresponding to the maximum capacity. Therefore, the correction factors for the horizontal soil resistance was proposed to match the bearing capacity from the three-dimensional finite element analyses.