• 한국철도학회:학술대회논문집
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• 한국철도학회 2011년도 춘계학술대회 논문집
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• pp.1757-1763
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• 2011

In recent years, accordance to industrial development project on railway investment, adverse environmental issues of the investment, such as disputed cases about recycling and usage of Ballast Cleaner excavated soil, have been continuously increasing. It will not only enhance the regulation of soil contamination but take considerable time and cost in future. In this study, we investigated soil contamination and burnability with soil of Chungang Line, Taebaek Line, Chungbuk Line, in order to seize a possibility of recycling Ballast Cleaner excavated soil for the natural materials and substantial heat sources, which are necessary resources for cement manufacturing process. As a result of this study, It is found that Ballast Cleaner excavated soil is satisfied with a standard. The excavated soil contains a lot of cement ingredients and fossil fuel dust incurred from freight transportation, so it is expected to use for ingredients of cement and replacement of heat sources.

• 전기학회논문지
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• 제58권7호
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• pp.1263-1269
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• 2009

Stable and sustainable power supply means maintaining a certain level of power quality and service while securing energy resource and resolving environmental issues. Distributed generation (DG) has become an essential and indispensable element from environmental and energy security perspectives. It is known that voltage violation is the most important constraint for load variation and the maximum allowable DG. In distribution system, sending voltage from distribution substation is regulated by ULTC (Under Load Tap Changer) designed to maintain a predetermined voltage level. ULTC is controlled by LDC (Line Drop Compensation) method compensating line voltage drop for a varying load, and the sending voltage of ULTC calls for LDC parameters. The consequence is that the feasible LDC parameters considering variation of load and DG output are necessary. In this paper, we design each LDC parameters determining the sending voltage that can satisfy voltage level, decrease ULTC tap movement numbers, or increase DG introduction. Moreover, the maximum installable DG capacity based on each LDC parameters is estimated.

• 전력전자학회:학술대회논문집
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• 전력전자학회 1998년도 Proceedings ICPE 98 1998 International Conference on Power Electronics
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• pp.780-784
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• 1998

A novel active input unbalance voltage compensator with harmonic current compensating capability is proposed and the operating principle of the proposed system is presented in the 3-phase power system. The proposed system performs both the voltage regulation of the load and the compensation of the harmonic currents generated due to nonlinear load such as diode rectifier. The system to compensate unbalanced voltage and hramonic currents is composed of a 3-phase voltage source inverter, LC filter, series transformer and passive devices at the load side of the line. The compensating voltage to regulate the load voltage and to remove the harmonic current components is transmitted to the line by the series transformer. The validity of the line by the series transformer. The validity of the proposed system is proved by the results of computer simulation.

• 한국정밀공학회지
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• 제20권4호
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• pp.214-222
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• 2003

Studies on the optimization of machining process can be divided into two different approaches: off-line feedrate scheduling and adaptive control. Each approach possesses its respective strong and weak points compared to each other. That is, each system can be complementary to the other. In this regard, a combined system, which is a feedrate control system fur cutting force optimization, was proposed in this paper to make the best of each approach. Experimental results show that the proposed system could overcome the weak points of the off-line feedrate scheduling system and the adaptive control system. In addition, from the figure, it can be confirmed that the off-line feedrate scheduling technique can improve the machining quality and can fulfill its function in the machine tool which has a adaptive controller.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2006년도 추계학술대회 논문집
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• pp.130-137
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• 2006

In these days abnormal climate occurs frequently because of global warming and earthshock. So it is necessary to prepare for the abnormal conditions like gale, rainfall, heavy snow and high temperature. Fortunately, Korea high speed rail(KTX) have a safety climate detection system for the abnormal weather by using CTC. So the safety is guaranteed in most aspect. But in convention line there isn't any alarm system for the abnormal condition and the train runs until the railroad loss occurred. So convention line need additional regulation same as KTX for the abnormal climate and in the near future passenger safety must be protected by new alarm system.

• Food Science and Biotechnology
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• 제17권6호
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• pp.1305-1309
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• 2008

Baicalein, one of the major flavonoid in Scutellaria baicalensis, has been known for its effects on proliferation and apoptosis of many tumor cell lines. Most biological effects of baicalein are thought to be from its antioxidant and prooxidant activities. In this report, baicalein was found to induce apoptosis in HL60 human promyelocytic leukemia cell line. Baicalein treatment induced DNA fragmentation and typical morphological features of apoptosis. To elucidate the mechanism of baicalein-induced apoptosis, the activities of the members of caspase family were measured. Interestingly caspase 2, 3, and 6 were significantly activated whereas caspase 1, 8, and 9 were not activated, suggesting selective involvement of specific caspases. Further, treatment with caspase inhibitors also supports the involvement of caspase 2 in apoptosis process. Although it has been reported that baicalein can induce apoptosis through many caspase pathways, the present study indicates that caspase 2 not caspase 9 pathway may be the important step in apoptosis on HL60 cell line.

• 대한전기학회논문지:전기기기및에너지변환시스템부문B
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• 제52권8호
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• pp.405-412
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• 2003

This paper presents a three-phase Line-Interactive uninterruptible power supply (UPS) system with series-parallel active power-line conditioning capabilities, using synchronous reference frame (SRF) based controller, which allows an effective power factor correction, source harmonic voltage compensation, load harmonic current suppression, and output voltage regulation. The three-phase UPS system consists of two active power compensator topologies. One is a series active compensator, which works as a voltage source in phase with the source voltage to have the sinusoidal source current and high power factor under the deviation and distortion of the source voltage. The other is a parallel active compensator which works as a conventional sinusoidal voltage source in phase with the source voltage, providing to the load a regulated and sinusoidal voltage with low THD (total harmonic distortion). The control algorithm using SRF method and the active power flow through the Line-interactive UPS systems are described and studied. The simulation and experimental results are depicted in this paper to show the effect of the proposed algorithm.

• Journal of the Korean Wood Science and Technology
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• 제46권2호
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• pp.166-177
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• 2018

Plant essential oils are defined as fragrant volatile oils extracted from leaves, stems, fruits, flowers, and roots of a plant. Such oils are composed of multiple components and multiple functions. By accumulation of inductive information, various plant essential oils have been studied for using in therapeutic medicine for various diseases. Despite of the apparent advantages of essential oils as a source of therapeutic medicines, plant essential oils have many limitations, including cytotoxic side effects. Therefore, it is necessary to evaluate the toxicity and the mechanisms of cytotoxicity of such oils. In this study, we evaluated the cytotoxicity to human-derived cell lines of 10 plant essential oils provided by National Institute of Forest Science (i.e., Larix kaempferi; Abies holophylla; Zanthoxylum ailanthoides; Pinus parviflora; Tsuga sieboldti; Chamaecyparis pisifera; Cryptomeria japonica; Pinus densiflora; Illicium anisatum; Pinus thunbergii). Cytotoxicity evaluations were accomplished by using CCK-assays and PCR-based cytotoxicity-related marker gene analyses with A549 cell line, and the Detroit551 cell line which are lung and skin cell line. The genes were analyzed included caspase-3 has a role in cell apoptosis, and the other cyclinA, cyclinB, cyclinD, and cyclinE regulated cell cycling for the cell proliferation. By examining the five cytotoxicity-related marker genes by performing real-time PCR and examined the cytostatic gene regulation associated with the various essential oils. The results of this study showed that the degree of cytotoxicity and the cytostatic gene regulation which could give precious information for using the plant essential oil for the clinical usages.

• Molecules and Cells
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• 제28권6호
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• pp.521-527
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• 2009

Previously, we have reported tissue- and stage-specific expression of miR-372 in human embryonic stem cells and so far, not many reports speculate the function of this microRNA (miRNA). In this study, we screened various human cancer cell lines including gastric cancer cell lines and found first time that miR-372 is expressed only in AGS human gastric adenocarcinoma cell line. Inhibition of miR-372 using antisense miR-372 oligonucleotide (AS-miR-372) suppressed proliferation, arrested the cell cycle at G2/M phase, and increased apoptosis of AGS cells. Furthermore, AS-miR-372 treatment increased expression of LATS2, while over-expression of miR-372 decreased luciferase reporter activity driven by the 3' untranslated region (3' UTR) of LATS2 mRNA. Over-expression of LATS2 induced changes in AGS cells similar to those in AGS cells treated with AS-miR-372. Taken together, these findings demonstrate an oncogenic role for miR-372 in controlling cell growth, cell cycle, and apoptosis through down-regulation of a tumor suppressor gene, LATS2.

• 대한미생물학회지
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• 제35권1호
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• pp.9-18
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• 2000

Immunological mechanisms involving the release of inflammatory factors by HIV-1 infected microglia in the brain have been implicated in the pathogenesis of HIV dementia (HIVD). Since the regulation of matrix metalloproteinases (MMPs) activity can be influenced by variety of inflammatory mediators, this study was undertaken to look for a correlation between the MMP-9 release and the production of TNF-${\alpha}$ in response to HIV-1 p24 in the human monocyte cell line THP-1 as a model for microglia. First, it was shown that HIV-l core p24 antigen induced THP-1 to secrete MMP-9 in a dose response manner while it elicited a little effect on MMP-2 release in human astroglial cell line T98G. Next, it was found that p24 induced THP-1 to secrete TNF-${\alpha}$ without prior differentiation into macrophages by phorbol myristate acetate (PMA) treatment. Furthermore, anti-TNF-${\alpha}$ neutralizing antibodies significantly blocked p24-induced MMP-9 release in a dose dependent manner. Our data indicate that p24 antigen induces monocytic MMP-9 release by triggering up-regulation of TNF-${\alpha}$ secretion.