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Release of the Pro-inflammatory Cytokines and Facilitation of Immune Response in LPS-induced Activation of Macrophage by Crude Cordycepin Containing Adenosine(CCCA) from Cordyceps militaris

  • Han, Shin-Ha;Lee, Seung-Jeong;Song, Young-Cheon;Lim, Hee-Jung;Lee, Chong-Kil;Kwon, Oh-Seung;Ha, Nam-Joo;Kim, Kyung-Jae
    • Proceedings of the PSK Conference
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    • 2003.10b
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    • pp.139.2-139.2
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    • 2003
  • The in vitro effects of extracted fractions of C. militaris on the secretion of cytokines in murine macrophage cell line, RAW 264.7 were studied. F1 (crude cordycepin containing adenosine), F2 (ethanol precipitation), F3 (ethanol soluble supernatant) and F4 (fraction of through SK-1B) significantly stimulated the production of cytokine and nitric oxide (NO) on murine macrophage cell line RAW264.7. We examined how the ethanol extract of C. militaris regulates production of interleukine 1-beta(IL-1$\beta$), tumor necrosis factor-alpha (TNF-$\alpha$), and NO in vitro. (omitted)

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Efficacy of Taxane-Based Regimens in a First-line Setting for Recurrent and/or Metastatic Chinese Patients with Esophageal Cancer

  • Jiang, Chang;Liao, Fang-Xin;Rong, Yu-Ming;Yang, Qiong;Yin, Chen-Xi;He, Wen-Zhuo;Cai, Xiu-Yu;Guo, Gui-Fang;Qiu, Hui-Juan;Chen, Xu-Xian;Zhang, Bei;Xia, Liang-Ping
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.13
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    • pp.5493-5498
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    • 2014
  • Objective: To compare the efficacy of taxane-based regimens in the first line setting retrospectively in Chinese patients with recurrent and/or metastatic esophageal cancer. Methods: We analyzed 102 recurrent and/or metastatic esophageal cancer patients who received taxanes-based regimens in a first-line setting from January 2009 to December 2013. Sixteen (15.7%) patients were administered Nab-PTX based chemotherapy and 86 patients (84.3%) received paclitaxel (PTX) or docetaxel (DTX) based chemotherapy. Patients in the PTX/DTX group could be further divided into TP (71 patients) and TPF (15 patients) groups. Results: The objective response rate (ORR) of all patients was 20.6%, and the disease control rate (DCR) was 67.6%. The median overall survival (OS) was 10.5 months (95% CI 10.1-16.4) and the median progression-free survival (PFS) was 6.04 months (95% CI 5.09-7.91). The DCR was higher in the TPF group than the TP group (93.3% vs. 59.1%; p = 0.015 ). There were no significant differences in ORR, OS, and PFS among Nab-PTX, TPF and TP groups. Conclusions: The three regimens of Nab-PTX based, TP and TPF proved active in a first line setting of Chinese patients with recurrent and/or metastatic esophageal cancer, and should thus be regarded as alternative treatments.

Islanding detection algorithm for a micro-grid based on the active and reactive power in the time domain (시간영역에서의 유효/무효전력을 이용한 마이크로그리드의 단독운전의 판단 알고리즘)

  • Lee, Young-Gui;Lee, Hye-Won;Kim, Yeon-Hee;Zheng, Tai-Ying;Kang, Yong-Cheol
    • Proceedings of the KIEE Conference
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    • 2011.07a
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    • pp.145-146
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    • 2011
  • A micro-grid (MG) is usually interconnected to the main grid through the dedicated line. Immediately after the removal of the grid supply, the MG should be disconnected and remain disconnected until the main grid is re-energized. It should detect islanding condition as soon as it happens to adjust the setting of the protection relays in the MG. This paper proposes an islanding detection algorithm for the MG based on the active and reactive power delivered to the dedicated line in the time domain. The performance of the proposed algorithm is verified under islanding conditions and fault conditions using the PSCAD/EMTDC simulator. The results indicate that the proposed algorithm can discriminate the islanding conditions from the various fault conditions.

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Mg II LINE VARIATION OF 32 CYGNI

  • Kang, Young-Woon
    • Journal of Astronomy and Space Sciences
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    • v.9 no.2
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    • pp.154-164
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    • 1992
  • The Mg II lines been extracted from the IUE archival spectra of 32 Cygni to investigate the effect of the atmospheric eclipse. The UV light curve has been reduced from the continuum flux at the center wavelength of 2807.5 ${\AA}$ in the IUE spectra. The equivalent width of the Mg II k absoption line has been measured for each spectra. The results of the light variation and flux tracing of the absorption line at the vicinity of the primary eclipse confirmed the atmospheric eclipse. The atmospheric effect lasted until the phase 0.06 in the absorptin line tracing, while it lasted until the phase 0.02 in the UV light curve, respectively.

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On the Limitation of Telegrapher′s Equations for Analysis of Nonuniform Transmission Lines

  • Kim, Se-Yun
    • Journal of electromagnetic engineering and science
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    • v.4 no.2
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    • pp.68-71
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    • 2004
  • The limitation of telegrapher's equations for analysis of nonuniform transmission lines is investigated here. It is shown theoretically that the input impedance of a nonuniform transmission line cannot be derived uniquely from the Riccati equation only except for the exponential transmission line of a particular frequency-dependent taper. As an example, the input impedance of an angled two-plate transmission line is calculated by solving the telegrapher's equations numerically. The numerical results suffer from larger deviation from its rigorous solution as the plate angle increases.

A Studies on Aging Properties for Transmission Line Polymer Insulators which are Installed in service (실계통에 포설된 송전용 고분자 애자의 AGING 특성 연구)

  • Kim, So-Yeon;Lee, Sang-Jin;Ha, Young-Kil;Kim, Dong-Wook
    • Proceedings of the KIEE Conference
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    • 2001.11a
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    • pp.152-154
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    • 2001
  • Recently the extensive use of composite insulators for transmission lines can ultimately be justified only on long-term qualification tests. Especially, it is possible for the Polymer insulator to be aged in according to the environment in which it is used this may bring about the decrease of the duration of voltage application. So, this paper deals with aging property of the polymer insulator installed at real transmission line in the industry area. The contact angle, arc test, tracking test were measured for acquiring the degradation characteristics of silicone rubber and the SEM, XRF, FT-IR tests were measured for analyzing the crack and components. Also the surface leakage current of the polymer insulator was compared with that of the porcelain insulator. Finally, we knew that the aging property was not appeared during seven months at real transmission line in the industry area.

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The Feasibility Study on a High-Temperature Application of the Magnetostrictive Transducer Employing a Thin Fe-Co Alloy Patch

  • Heo, Tae-Hoon;Park, Jae-Ha;Ahn, Bong-Young;Cho, Seung-Hyun
    • Journal of the Korean Society for Nondestructive Testing
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    • v.31 no.3
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    • pp.278-286
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    • 2011
  • The on-line monitoring for the wall thinning in secondary system has been considered one of main issues for the safety of nuclear power plants. To establish the on-line monitoring technique for the pipe wall thinning, the development of the ultrasonic transducer working in high-temperature is very important. In this investigation, the magnetostrictive transducer is concerned for high temperature condition up to $300^{\circ}C$. The magnetostrictive transducer has many advantages such as high working temperature, durability, cost-effectiveness, and shear waves, most of all. A thin Fe-Co alloy patch whose Curie temperature is over $900^{\circ}C$ was employed as a ferromagnetic material for magnetostriction. Wave transduction experiments in various temperature were carried out and the effect of bias magnets was considered together with the dry coupling performance of the transducer. From experimental results, consequently, it was found that the magnetostrictive transducer works stable even in high temperature up to $300^{\circ}C$ and can be a promising method for the on-line monitoring of the wall thinning in nuclear power plants.

A Development and Performance Test of Voltage Measurement Accuracy Assessment System for Distribution Equipment (배전기기 전압계측 정밀도 평가시스템 개발 및 성능시험)

  • Cho, Jin-Tae;Kim, Ju-Yong;Lee, Hak-Ju;Kim, Jae-Han
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.27 no.9
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    • pp.83-89
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    • 2013
  • Power distribution system has been changed from radial system to closed loop or mesh system due to connection of distributed generation growth. Data from distribution equipments which are installed at distribution line is required to be accurate for the performance of DMS(Distribution Management System). This paper analyzes the voltage measurement data from distribution equipment. However, the results of the analysis are confirmed to have some errors in voltage measurement data from distribution equipment. These errors come from aging of voltage sensor in distribution equipment and inaccurate data transfer to FRTU(feeder remote terminal unit) through the controller. The main problem is that the voltage measurement data of distribution equipment can not be assessed after it's first installation at the distribution line. The voltage measurement accuracy assessment system is to assess the voltage measurement data from distribution equipment on hot-line. This study had a field test to verify the performance of system.

X-ray Absorption Near-edge Studies of Au1-xPtx alloys

  • Y.D. Chung;Lim, K.Y.;Lee, Y.S.;C.N.Whang;Park, B.S.;Y.Jeon
    • Proceedings of the Korean Vacuum Society Conference
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    • 2000.02a
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    • pp.164-164
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    • 2000
  • Since Au-Pt alloys have various atomic structures depending upon composition and annealing temperature, it is very interesting to investigate the electronic structures of alloys. We studied the changes of the electronic structure I the Au-Pt alloys by x-ray absorption near edge spectroscopy (XANES). Two kinds of Au-Pt alloy samples were prepared by arc melting methods and ion-beam-mixing technique. The Pt L2, 3-edge and Au L2, 3-edge X-ray absorption spectra (XPS) were measured with the electron yield mode detector at the 3C1 beam line of the Pohang Light Source (PLS). It was found that there was a substantial decrease in the area of the Pt L2, 3 white lines compared with that of pure Pt. The observed decrease in white line area was attributed to an increase in the number of pure Pt. The observed decrease in white line area was attributed to an increase in the number of 5d-electrons at the Pt site upon alloy formation. However, the Au L2, 3 edge spectra for Au-Pt alloys are all similar to that of pure Au. This implies that the 5d hole count of Au is not changed by alloy formation with Pt.

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Reverberation Mapping of Nearby AGN with Medium-band and LSGT

  • Kim, Joonho;Im, Myungshin;Choi, Changsu;Hwang, Sungyong
    • The Bulletin of The Korean Astronomical Society
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    • v.45 no.1
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    • pp.34.2-34.2
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    • 2020
  • Reverberation mapping is one of the best ways to investigate the physical mechanism of broad-line regions around central supermassive black holes of active galactic nuclei (AGNs). It is usually used to estimate the masses of supermassive black holes. Although spectroscopic reverberation mapping has used to study dozens of AGN, spectroscopic monitoring campaign of large sample is expansive. Here, we present results of photometric reverberation mapping with medium-band photometry. We monitored five nearby AGN which were already studied with H-alpha emission line. Observation has been performed for ~3 months with ~3 days cadence using three medium-band filters installed in LSGT (Lee Sang Gak Telescope; 0.43m). We found 0.01-0.08 magnitude variations from differential photometry. Also time-lags between continuum light-curves and H-alpha emission line light-curves are found using JAVELIN software. The result shows that our study and previous studies are consistent within uncertainty range. In the near future, medium-band photometric reverberation mapping seems useful to study large AGN samples. We will present preliminary result of following study that report new time lag measurement of six AGNs in the similar way.

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