• Bulletin of the Korean Chemical Society
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• v.33 no.9
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• pp.2991-2998
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• 2012

A series of new diarylureas and diarylamides possessing 1,3,4-triarylpyrazole scaffold was synthesized and their in vitro antiproliferative activities against A375P human melanoma cell line and NCI-60 cell line panel were tested. Compounds 9, 11, 12, 14, and 17-21 showed superior potency against A375P to Sorafenib. Over the NCI-60 cancer cell line panel, compound 14 possessing a methoxy group, amide linker, and 4-chloro-3-(trifluoromethyl)phenyl terminal ring showed the highest potency and broad-spectrum anticancer activity. Compound 13 showed high selectivity towards leukemia subpanel over other cancer types.

• Journal of Advanced Marine Engineering and Technology
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• v.37 no.7
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• pp.752-759
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• 2013

This paper presents a method for analyzing and designing an extremely miniaturized planar ring hybrid, using the combination of parallel and diagonally shorted coupled lines. In contrast to conventional miniaturized coupled line filters, it is proven that the required electrical length of transmission line can be largely reduced to even a few degrees, not only effectively suppressing the spurious passband but also approximately maintaining the same characteristic around the stable center frequency. A ring hybrid filter at center frequency of 1 GHz was fabricated on the FR4 epoxy glass cloth copper-clad plat (CCL) PCB substrate. The insertion loss of a ring hybrid filter with the die area of $30mm{\times}30mm$ is -4.68 dB. Simulated results are well agreed with the measurements.

• Proceedings of the KIEE Conference
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• 2006.11a
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• pp.317-319
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• 2006

This paper proposes a fault location algorithm for two-parallel transmission line in the case of single line-to-ground fault Proposed algorithm is using voltage and current measured in the sending-end. The fault distance is simply determined by solving a second order polynomial equation due to the direct circuit analysis. The simulations by PSCAD/EMTDC have demonstrated the accuracy and effectiveness of the proposed algorithm.

• Journal of Ginseng Research
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• v.22 no.3
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• pp.188-192
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• 1998

We established the model of clonogenic assay with human tumor cell line such as Calu-3 (lung carcinoma), HEC- lB (endometrial adenocarcinoma) , HEp-2 (larnyx carcinoma), Hs-5787 (breast carcinoma), K-562 (chronic myelogenous leukemia), SF-188 (brain carcinoma), SNU-1 (stomach carcinoma) and WiDr (colon carcinoma) . We investigated growth inhibition of solvent (EtOH, MeOH) and water (100$^{\circ}C$, 121$^{\circ}C$) extracts from Korean red ginseng by clonogenic assay. The results of clonogenic assay showed that EtOH extract had growth inhibition against Calu-3, SF-188 and SNU-1, MeOH extract had growth inhibition against Calu-3, Hs-5787, K-562, and WiDr, but water extract at 100$^{\circ}C$ and water extract at 121$^{\circ}C$ had not growth inhibition against used cell lines.

• Journal of Information Display
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• v.13 no.3
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• pp.125-130
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• 2012

In this paper, a new precharging method without any side effects is proposed to overcome image degradation caused by insufficient charging times. This work explains why the precharging method can compensate for short charging times. However, side effects of the precharging method in the form of horizontal line artifacts are addressed, wherein line artifact-compensating precharging (LCP) is presented to mitigate the side effects. Behavioral modeling is employed to investigate the side effects by estimating transient responses of a liquid crystal display. The LCP proves that it can dramatically reduce line artifacts caused by precharging because the brightness difference of adjacent pixels does not exceed 1.0.

• Transactions of the Korean Society of Machine Tool Engineers
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• v.17 no.3
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• pp.115-121
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• 2008

A knowloedge of the residual stress distribution at circumferential welds can increase the prediction accuracy of a fracture assessment in pipe lines. In this study, in order to predict the residual stress distribution in the circumferential butt-welded pipes were measured, using the hole-drilling strain gauge method. Their practical applications were performed in to two kinds of pipes. As the results, the following characteristics were found. On the inner surface of pipes, the circumferential and axial residual stresses were both tensile near the center line of welding and both of them changed from tensile to compressive as the distance from the center line increased. On the outer surface, however, the circumferential residual stress was shown to be tensile wile the axial residual stress was compressive near the center line of welding, and later they were revered at the region far away from the centerline.

• Proceedings of the KIEE Conference
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• 1988.07a
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• pp.774-777
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• 1988

This paper covers the insulation coordination of 765 KV transmission line in Korea Electric Power Corporation. The design for the lightning, switching surge, and contamination was conducted to increase the reliability of 765 KV line. The authors have used the result of a limited Westinghouse ANACOM swiching surge study of the Korea Electric Corporation's 765 KV Expansion plan. The study investigated the switching surge overvoltage distribution and maximum switching overvoltage when relosing 765 KV lines. They used the technical data of the suspension insulator for the contamination design, which was available from a foreign insulator manufacture. From this paper, the authors find out that the contamination design dominates to determine the number of insulator and the SOV design dominates the air clearance in the tower. Afterwards the authors will confirm this design by Demonstration Test with Korea Electro-technology Research Institute.

• Bulletin of the Korean Chemical Society
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• v.34 no.8
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• pp.2311-2316
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• 2013

A series of new diarylamide and diarylurea derivatives possessing pyrimidinylaminobenzene scaffold was synthesized. Their in vitro antiproliferative activities were tested against A375P human melanoma cell line. Among them, compounds 1a-c, k and 2b-d, f, g, j, l showed superior potencies against A375P human melanoma cell line to Sorafenib. In particular, compound 2f possessing 3-fluoro-5-trifluoromethyl moiety exhibited the highest potency with $IC_{50}$ value in nanomolar scale.

• Proceedings of the KIEE Conference
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• 2005.10c
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• pp.235-237
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• 2005

This study investigates Characteristic analysis of Line-start Synchronous Reluctance Motor to substitute for Induction Motor. The results of machine characteristics are analyzed by simulation using Flux2D. Characteristic analysis result of Line-start Synchronous Reluctance Motor is confirmed by the Experimental result.

• Proceedings of the KIEE Conference
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• 2005.07b
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• pp.933-935
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• 2005

This study investigates Characteristic analysis of Line-start Synchronous Reluctance Motor to substitute for Induction Motor. The results of machine characteristics are analyzed by simulation using Flux2D. Characteristic analysis result of Line-start Synchronous Reluctance Motor is confirmed by the analysis result of 3-Phase Induction Motor.