• Title/Summary/Keyword: likelihood ratio statistics

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Prognostic Value of the Anatomic Region of Metastatic Lymph Nodes in the Current TNM Staging of Gastric Cancer

  • Jeong, Oh;Jung, Mi Ran;Kang, Ji Hoon
    • Journal of Gastric Cancer
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    • v.21 no.3
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    • pp.236-245
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    • 2021
  • Purpose: The numeric N stage has replaced the topographic N stage in the current tumor node metastasis (TNM) staging in gastric carcinoma. However, the usefulness of the topographic N stage in the current TNM staging system is uncertain. We aimed to investigate the prognostic value of the topographic N stage in the current TNM staging system. Materials and Methods: We reviewed the data of 3350 patients with gastric cancer who underwent curative gastrectomy. The anatomic regions of the metastatic lymph nodes (MLNs) were classified into 2 groups: perigastric and extra-perigastric. The prognostic value of the anatomic region was analyzed using a multivariate prognostic model with adjustments for the TNM stage. Results: In patients with lymph node metastasis, extra-perigastric metastasis demonstrated significantly worse survival than perigastric metastasis alone (5-year survival rate, 39.6% vs. 73.1%, respectively, P<0.001). Extra-perigastric metastasis demonstrated significantly worse survival within the same pN stage; the multivariate analysis indicated that extra-perigastric metastasis was an independent poor prognostic factor (hazard ratio=1.33; 95% confidence interval=1.01-1.75). The anatomic region of the MLNs improved the goodness-of-fit (likelihood ratio statistics, 4.57; P=0.033) of the prognostic model using the TNM stage. Conclusions: The anatomic region of MLNs has an independent prognostic value in the numeric N stage in the current TNM staging of gastric carcinoma.

Nicotine dependence and the International Association for the Study of Pain neuropathic pain grade in patients with chronic low back pain and radicular pain: is there an association?

  • Schembri, Emanuel;Massalha, Victoria;Spiteri, Karl;Camilleri, Liberato;Lungaro-Mifsud, Stephen
    • The Korean Journal of Pain
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    • v.33 no.4
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    • pp.359-377
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    • 2020
  • Background: This study investigated whether current smoking and a higher nicotine dependency were associated with chronic low back pain (LBP), lumbar related leg pain (sciatica) and/or radicular neuropathic pain. Methods: A cross-sectional study was conducted on 150 patients (mean age, 60.1 ± 13.1 yr). Demographic data, the International Association for the Study of Pain (IASP) neuropathic pain grade, STarT Back tool, and the Fagerström test were completed. A control group (n = 50) was recruited. Results: There was a significant difference between current smokers and nonsmokers in the chronic LBP group in the mean pain score (P = 0.025), total STarT Back score (P = 0.015), worst pain location (P = 0.020), most distal pain radiation (P = 0.042), and in the IASP neuropathic pain grade (P = 0.026). There was a significant difference in the mean Fagerström score between the four IASP neuropathic pain grades (P = 0.005). Current smoking yielded an odds ratio (OR) of 3.071 (P = 0.011) for developing chronic LBP and sciatica, and an OR of 4.028 (P = 0.002) for obtaining an IASP "definite/probable" neuropathic pain grade, for both cohorts. The likelihood for chronic LBP and sciatica increased by 40.9% (P = 0.007), while the likelihood for an IASP neuropathic grade of "definite/probable" increased by 50.8% (P = 0.002), for both cohorts, for every one unit increase in the Fagerström score. Conclusions: A current smoking status and higher nicotine dependence increase the odds for chronic LBP, sciatica and radicular neuropathic pain.

Application of sequential analysis in internet shopping malls (인터넷 쇼핑몰에서의 축차분석법 활용 방안)

  • Park, Hee-Chang
    • Journal of the Korean Data and Information Science Society
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    • v.20 no.6
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    • pp.1009-1014
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    • 2009
  • The Internet has changed the daily lives of human being in Korea and elsewhere in the world. It has changed the paradigms of traditional commercial activities and created immense opportunities for new business models. Recently, there has been much attention to the internet shopping mall as a means of commercial transaction. To make internet shopping mall competitive, effective customer satisfaction service should be provided and it is necessary to dynamic analysis method for customers' purchasing pattern. In this paper we apply the sequential analysis to comparison of two kinds of sales through the analysis of customers' purchasing pattern.

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Testing Independence in Contingency Tables with Clustered Data (집락자료의 분할표에서 독립성검정)

  • 정광모;이현영
    • The Korean Journal of Applied Statistics
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    • v.17 no.2
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    • pp.337-346
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    • 2004
  • The Pearson chi-square goodness-of-fit test and the likelihood ratio tests are usually used for testing independence in two-way contingency tables under random sampling. But both of these tests may provide false results for the contingency table with clustered observations. In this case we consider the generalized linear mixed model which includes random effects of clustering in addition to the fixed effects of covariates. Both the heterogeneity between clusters and the dependency within a cluster can be explained via generalized linear mixed model. In this paper we introduce several types of generalized linear mixed model for testing independence in contingency tables with clustered observations. We also discuss the fitting of these models through a real dataset.

Chi-Squared Test of Independence in Case that Two Marginal Distributions are Given Exactly (모집단 부분정보가 주어진 상황에서의 분할표 독립성 검정)

  • 이광진
    • The Korean Journal of Applied Statistics
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    • v.17 no.1
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    • pp.89-103
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    • 2004
  • If the given information is exact, though it is the little, we had better use it than not use in analysis. In this article, the problem of independence test in a contingency table is considered when two marginal distributions of a population are given exactly. For that case, a likelihood-ratio chi-squared test statistic and its Pearsonian type chi-squared test statistic are derived. By Monte Carlo Simulations the traditional chi-square tests and the derived tests are compared. And the related some testing problems are synthetically explained on a geometrical viewpoint.

A Novel Spectrum Sensing Scheme for Cognitive Radio with Receive Diversity: Performance Analysis in Non-Fading Channel (수신 다양성을 쓰는 인지 무선통신에 알맞은 새로운 주파수 검출 기법: 경로 감쇄가 없을 때의 성능 분석)

  • Kang, Hyun Gu;Song, Iickho;Bae, Jinsoo;Min, Hwang-ki;Kim, Dongjin
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.3 no.4
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    • pp.49-69
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    • 2010
  • In this paper, we propose a class of spectrum sensing schemes for cognitive radio with receive diversity. By considering the generalized likelihood ratio test detector in each branch and exploiting non-linear diversity combining strategy, the proposed scheme exhibits reasonable performance for spectrum sensing even in the environment of heavier-tailed noise. From the results of analysis and computer simulations, it is observed that the proposed scheme provides significant performance gain and performance stability over the conventional schemes, especially in impulsive noise environment.

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The Use of Confidence Interval of Measures of Diagnostic Accuracy (진단검사 정확도 평가지표의 신뢰구간)

  • Oh, Tae-Ho;Pak, Son-Il
    • Journal of Veterinary Clinics
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    • v.32 no.4
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    • pp.319-323
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    • 2015
  • The performance of diagnostic test accuracy is usually summarized by a variety of statistics such as sensitivity, specificity, predictive value, likelihood ratio, and kappa. These indices are most commonly presented when evaluations of competing diagnostic tests are reported, and it is of utmost importance to compare the accuracies of diagnostic tests to decide on the best available test for certain medical disorder. However, it is important to emphasize that specific point values of these indices are merely estimates. If parameter estimates are reported without a measure of uncertainty (precision), knowledgeable readers cannot know the range within which the true values of the indices are likely to lie. Therefore, when evaluations of diagnostic accuracy are reported the precision of estimates should be stated in parallel. To reflect the precision of any estimate of a diagnostic performance characteristic or of the difference between performance characteristics, the computation of confidential interval (CI), an indicator of precision, is widely used in medical literatures in that CIs are more informative to interpret test results than the simple point estimates. The majority of peer-reviewed journals usually require CIs to be specified for descriptive estimates, whereas domestic veterinary journals seem less vigilant on this issues. This paper describes how to calculate the indices and associated CIs using practical examples when assessing diagnostic test performance.

Analysis of Household Income and Expenditure of Households with a Negative Cash Flow Across Income Groups in 2000, 2005, and 2010 (소득계층별 적자가계의 소비 지출 분석: 2000, 2005, 2010년의 가계를 대상으로)

  • Lee, Jonghee;Yang, Sejeong
    • Journal of Families and Better Life
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    • v.32 no.5
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    • pp.125-143
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    • 2014
  • The purpose of this study was to gain a better understanding of households with a negative cash flow. The Household Budget Survey conducted in 2000, 2005, and 2010 by the Bureau of Statistics in South Korea were used for this study. The households used in this study were divided into four groups according to their income levels; they were categorized the lowest, low, middle, and high income groups. This study made several findings regarding households with a negative/positive cash flow. Firstly, the demographic and economic characteristics were different between those who have a negative cash flow and those with a positive cash flow. A female household head, a household head age 65 and older, a household head with a lower educational attainment, an unemployed household head, and the presence of a child/children in schools were related with the household deficit. Secondly, the households with a positive cash flow had a higher income level compared to the households with a negative cash flow, while the households with a negative cash flow had a much higher consumption level compared to the households with a positive cash flow. Thirdly, the household deficit to total income ratio of the lowest income group was higher when compared to any other income group. Lastly, the multivariate statistics showed that households including a child/children in schools are more likely to be a household with a negative cash flow. Especially, the expenditures on education and transportation were related with the likelihood of a household deficit.

A Three Dimensional Study on the Probability of Slope Failure(II) (사면(斜面)의 삼차원(三次元) 파괴확률(破壞確率)에 관(關)한 연구(硏究)(II))

  • Kim, Young-Su;Tcha, Hong-Jun;Jung, Sung-Kwan
    • Journal of Industrial Technology
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    • v.3
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    • pp.53-63
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    • 1983
  • The probability of failure is used to analyze the reliability of three dimensional slope failure, instead of conventional factor of safety. The strength parameters are assumed to be normal variated and beta variated. These are interval estimated under the specified confidence level and maximum likelihood estimation. The pseudonormal and beta random variables are generated using the uniform probability transformation method according to central limit theorem and rejection method. By means of a Monte-Carlo Simulation, the probability of failure is defined as; Pf=M/N N : Total number of trials M : Total number of failures Some of the conclusions derived from the case study include; 1. Three dimensional factors of safety are generally much higher than 2-D factors of safety. However situations appear to exist where the 3-D factor of safety can be lower than the 2-D factor of safety. 2. The F3/F2 ratio appears to be quite sensitive to c and ${\phi}$ and to the shape of the 3-D shear surface and the slope but not to be to the unit weight of soil. 3. In cases that strength parameters are assumed to be normal variated and beta variated, the relationships between safety factor and the probability of failure are fairly consistent, regardless of the shape of the 3-D shear surface and the slope. 4. As the c-value is increased, the probability of failure for the same safety factor is increased and as the ${\phi}-value$ is increased, the probability of failure for the same safety factor is decreased.

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Comparison of Video Laryngoscope and Direct Laryngoscope on Rapidity and Accuracy in Tracheal Intubation by Paramedic (1급 응급구조사의 비디오후두경 기관삽관과 직접후두경 기관삽관의 신속성 및 정확도 비교)

  • Sim, Gyu-Sik
    • The Korean Journal of Emergency Medical Services
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    • v.14 no.1
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    • pp.5-18
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    • 2010
  • Objective : This study compares Video laryngoscope and Direct laryngoscope in tracheal Intubation on rapidity and accuracy by paramedic and aims to improve efficiency of airway management and survival rate in pre-hospital treatment for the patients with severe trauma, cardiac arrest or dyspnea caused by acute diseases. Methods : 60 paramedics were recruited from 13 fire stations located in C province. With the consent of the paramedics, likelihood ratio test was carried out and they were divided into two different groups; DL group (30) and GVL group (30). Regarding intubation conditions, difficult airway grade I, grade II and grade III as well as sniffing position and neutral position were examined. This study also compared between ambulance in motion and in stand still. Frequency, average and standard deviation were analyzed with statistics program, SPSS WIN 17.0 and repeated measure design was introduced to examine inter-relations between position, grade and groups. Results : Intubation was performed more rapidly in neutral position and GVL than in sniffing position and DL(F = 15.260, p = .000). Rapidity value was better with grade I and grade II than grade III and better with GVL than DL(F = 32.629, p = .000). Accuracy value was higher with neutral position and GVL than sniffing position and DL(F = 5.008, p = .011). grade III was less accurate than grade I, grade II and GVL was more accurate than DL(F = 10.966, p = .000). Ambulance motion status did not show any statistically significant differences in accuracy and rapidity. Conclusion : Given this study results, neutral position is better for the patient with severe trauma. For a better survival, GVL intubation can be considered since GVL can enhance accuracy as well as rapidity regarding difficult airway. Since there is no significant differences in ambulance motion factors, intubation can be recommended even in moving ambulance for shortening traveling time to a hospital.

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