• 제목/요약/키워드: lifespan

검색결과 552건 처리시간 0.026초

A Study on the Lifetime Prediction of Lithium-Ion Batteries Based on the Long Short-Term Memory Model of Recurrent Neural Networks

  • Sang-Bum Kim
    • International Journal of Internet, Broadcasting and Communication
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    • 제16권3호
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    • pp.236-241
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    • 2024
  • Due to the recent emphasis on carbon neutrality and environmental regulations, the global electric vehicle (EV) market is experiencing rapid growth. This surge has raised concerns about the recycling and disposal methods for EV batteries. Unlike traditional internal combustion engine vehicles, EVs require unique and safe methods for the recovery and disposal of their batteries. In this process, predicting the lifespan of the battery is essential. Impedance and State of Charge (SOC) analysis are commonly used methods for this purpose. However, predicting the lifespan of batteries with complex chemical characteristics through electrical measurements presents significant challenges. To enhance the accuracy and precision of existing measurement methods, this paper proposes using a Long Short-Term Memory (LSTM) model, a type of deep learning-based recurrent neural network, to diagnose battery performance. The goal is to achieve safe classification through this model. The designed structure was evaluated, yielding results with a Mean Absolute Error (MAE) of 0.8451, a Root Mean Square Error (RMSE) of 1.3448, and an accuracy of 0.984, demonstrating excellent performance.

Acanthopanax sessiliflorus stem confers increased resistance to environmental stresses and lifespan extension in Caenorhabditis elegans

  • Park, Jin-Kook;Kim, Chul-Kyu;Gong, Sang-Ki;Yu, A-Reum;Lee, Mi-Young;Park, Sang-Kyu
    • Nutrition Research and Practice
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    • 제8권5호
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    • pp.526-532
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    • 2014
  • BACKGROUND/OBJECTIVES: Acanthopanax sessiliflorus is a native Korean plant and used as a traditional medicine or an ingredient in many Korean foods. The free radical theory of aging suggests that cellular oxidative stress caused by free radicals is the main cause of aging. Free radicals can be removed by cellular anti-oxidants. MATERIALS/METHODS: Here, we examined the anti-oxidant activity of Acanthopanax sessiliflorus extract both in vitro and in vivo. Survival of nematode C. elegans under stress conditions was also compared between control and Acanthopanax sessiliflorus extract-treated groups. Then, anti-aging effect of Acanthopanax sessiliflorus extract was monitored in C. elegans. RESULTS: Stem extract significantly reduced oxidative DNA damage in lymphocyte, which was not observed by leaves or root extract. Survival of C. elegans under oxidative-stress conditions was significantly enhanced by Acanthopanax sessiliflorus stem extract. In addition, Acanthopanax sessiliflorus stem increased resistance to other environmental stresses, including heat shock and ultraviolet irradiation. Treatment with Acanthopanax sessiliflorus stem extract significantly extended both mean and maximum lifespan in C. elegans. However, fertility was not affected by Acanthopanax sessiliflorus stem. CONCLUSION: Different parts of Acanthopanax sessiliflorus have different bioactivities and stem extract have strong anti-oxidant activity in both rat lymphocytes and C. elegans, and conferred a longevity phenotype without reduced reproduction in C. elegans, which provides conclusive evidence to support the free radical theory of aging.

건강 Ethyl acetate 분획의 선충에 대한 수명연장 효과 (Longevity Property of Ethyl acetate Fraction of Dried Zingiber officinale in Caenorhabditis elegans)

  • 이은별;김준형;임재윤;김혜수;김대성;김주은;김효신;이정호;문광현;정경옥;한순천;김대근
    • 생약학회지
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    • 제48권1호
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    • pp.25-30
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    • 2017
  • This study was performed to evaluate the lifespan extending effects of the dried ginger (Zingiber officnale Roscoe, Zingiberaceae). Ethanol extract of the dried ginger was successively partitioned as methylene chloride, ethyl acetate, n-butanol and $H_2O$ soluble fractions, and lifespan-extending effects of the fractions were investigated using Caenorhabditis elegans model system. Ethyl acetate-soluble fraction showed the most potent longevity property. Furthermore, ethyl acetate-soluble fraction elevated thermal stress tolerance, and increased expression of stress resistance protein. Further studies were performed to investigate several aging-related factors such as reproduction, food intake, growth and movement of C. elegans. The results revealed that there were no significant changes in aging-related factors including reproduction, food intake and growth, however, ethyl acetate-soluble fraction treatment led to an up-regulation of locomotory ability of aged worms, suggesting ethyl acetate-soluble fraction affected healthspan as well as lifespan of nematode.

Development of the Turnip Aphid, Lipaphis erysimi Kaltenbach (Homoptera: Aphididae), and Test of Insecticidal Efficacy of Some Commercial Natural Products

  • Kim, Dong-Young;Chang, Sung-Kwon;Jeong, Hyung-Uk;Kim, Min-Jee;Kim, Ik-Soo
    • International Journal of Industrial Entomology and Biomaterials
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    • 제16권2호
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    • pp.93-99
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    • 2008
  • The turnip aphid is a worldwide pest, damaging mainly to crucifers. In order to understand the life parameters of Lipaphis erysimi for the eventual goal of control, the developmental periods, survival rates, lifespan, and fecundity of the species were investigated under five temperature regimes ($15^{\circ}C-35^{\circ}C$). Furthermore, the efficacy of several environment-friendly agricultural materials (EFAMs) that are on the market was subjected to test in order to obtain further accurate information. The developmental period of the turnip aphid nymph was longest at $15^{\circ}C$ as 16.9 days, shortened as temperature goes up to $25^{\circ}C$ (5.4 days), and then somewhat increased at $30^{\circ}C$ (5.9 days), suggesting that the most efficient temperature for nymphal development could be around $25^{\circ}C$. Mortality of the nymphal turnip aphid was obvious at $35^{\circ}C$, whereas it was minimal at other temperature schemes. The longevity of adults shortened as temperature goes up to $30^{\circ}C$. In particular, the maximum lifespan for adults continued for 55 days at $15^{\circ}C$, but shortened to 21 days at $30^{\circ}C$. The total fecundity was 35.7 at $15^{\circ}C$, 81 at $20^{\circ}C$, 64.2 at $25^{\circ}C$, and 6.6 individuals at $30^{\circ}C$, showing the highest fecundity at $20^{\circ}C$. After the turnip aphids were successfully stabilized in indoor environment the insecticidal activity was tested and mortality was determined 12, 24, 36, and 48 hrs after EFAMs are treated. Several on-the-market EFAMs showed more than 90% of insecticidal activity within 24 hrs or 48 hrs, but a few showed less than 90% activity, signifying importance of selection of proper EFAMs.

개체배양에 의한 3 Types 윤충(Brachionus plicatilis)의 수명 및 번식력 (Lifespan and Fecundity of Three Types of Rotifer, Brachionus plicatilis by an Individual Culture)

  • ;허성범;김현준
    • 한국수산과학회지
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    • 제26권6호
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    • pp.511-518
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    • 1993
  • 해산어류의 종묘생산시 초기 동물먹이생물로 널리 이용되는 미소형, 소형, 대형 윤충(Brachionus plicatilis)의 환경요인에 따른 수명과 번식력을 조사하였다. 전반적으로 온도는 $25{\sim}27^{\circ}C$$20{\sim}22^{\circ}C$ 보다 번식력과 수명이 높았으며 미소형과 소형윤충은 이러한 현상이 더욱 뚜렷하였다. 염분은 미소형과 대형 윤충은 32ppt보다 16ppt에서 번식력이 더욱 높았던 반면 소형 윤충은 32ppt에서 더욱 높았다. 먹이생물은 미소형과 대형 윤충은 Tetraselmis tetrathele 소형 윤충은 Chlorella ellipsoidea가 더 좋은 먹이 효율을 보였다. 각 윤충의 먹이생물, 수온, 염분에 따른 최고의 번식력은 미소형 윤충은 Tetraselmis tetrathele, $25{\sim}27^{\circ}C$, 16ppt, 소형 윤충은 Chlorella ellipsoidea, $25{\sim}27^{\circ}C$, 32ppt ,대형 윤충은 Chlorella ellipsoidea, $25{\sim}27^{\circ}C$, 16ppt에서 나타났다.

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운동이 SAMP8 마우스의 노화와 기억장애에 미치는 영향 (Effects of Physical Training on Defence Mechanism of Aging and Memory Impairment of Senescence-accelerated SAMP8)

  • 구우영;이종수;곽이섭
    • IMMUNE NETWORK
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    • 제5권4호
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    • pp.252-257
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    • 2005
  • Background: This study was designed to investigate the effect of exercise training on defense mechanism of chronic degenerative disease, aging, and memory impairments of senescence-accelerated mouse (SAM)P8 under the hypothesis that "Senile dementia may be prevented by regular exercises". Methods: To evaluate the effects of exercise training on the defense mechanism of aging and memory impairment, SAMP8 were divided into two groups, the control group and exercise training groups. the exercise training group were performed with low $(\dot{V}O_2max\;25{\sim}33%)$, middle ($\dot{V}O_2max$ 50%) and high $(\dot{V}O_2max\;66{\sim}75%)$ intensity exercise. All SAMP8 mice were fed experimental diet ad libitum until 4, 8 months, and dead period. Results: Median lifespan in middle exercise group resulted in a significantly increased (23.5% and 18.7%, respectively), whereas these lifespan in high exercise group resulted in an unexpectedly decreased (13.5% and 12.1%, respectively) compared with control group. Body fat levels in 4 and 8 months of age were significantly decreased 43% to 51% in middle exercise group, whereas were remarkably deceased to 57% in high exercise group compared with control group. It is believed that extended median and maximum lifespan may be effected by calory restriction through the exercise training. Acetylcholine (ACh) levels were significantly increased 6.7% and 8.5% in middle and high exercise groups, and also choline acetyltransfease (ChAT) activities were significantly increased 10.3% and 11.9% in middle and high exercise groups. Conclusion: These results suggest that proper and regular exercises such as middle group ($\dot{V}O_2max$ 50%) may play an effective role in attenuating an oxygen radicals and may play an important role in improving a learning and memory impairments of senile dementia.

Role of Laparoscopic Gastrectomy in Very Elderly Patients with Gastric Cancer Who Have Outlived the Average Lifespan

  • Kim, Dong Jin;Kim, Wook
    • Journal of Gastric Cancer
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    • 제18권2호
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    • pp.109-117
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    • 2018
  • Purpose: This study aimed to investigate the outcomes of laparoscopic gastrectomy in very elderly patients with gastric cancer, who have outlived the average lifespan of the Korean population (men: ${\geq}77years$, women: ${\geq}84years$). Materials and Methods: Between 2004 and 2015, 836 patients with gastric cancer underwent a laparoscopic gastrectomy. They were divided into the elderly group (EldG) and non-elderly group (nEldG). Propensity score matching for covariates of sex, tumor depth, node status, and extent of resection was performed. Clinicopathologic characteristics, and surgical and survival outcomes were compared between the 2 groups. Results: The EldG had a higher American Society of Anesthesiologists (ASA) score and a higher number of comorbidities. There was no significant difference in the post-operative complications, except for pulmonary complications, which were more frequent in the EldG (5/56, 8.9%) than in the nEldG (0/56, 0%). The EldG had a shorter overall survival (OS), but cancer-specific survival was similar for both groups. Among deceased patients, 2 (25%) and 8 patients (50%) died within a year of surgery in the nEldG and EldG, respectively. Univariate and multivariate risk factor analyses for OS showed that age, ASA score, tumor, node, metastasis (TNM) stage, and occurrence of complications were significantly related to deterioration in OS. Conclusions: Laparoscopic gastrectomy can be safely performed in very elderly patients with gastric cancer who have outlived the average lifespan of the Korean population. However, impact of laparoscopic gastrectomy on improving survival is not clear, and careful patient selection is recommended.

Whole Genome Analysis of the Red-Crowned Crane Provides Insight into Avian Longevity

  • Lee, HyeJin;Kim, Jungeun;Weber, Jessica A.;Chung, Oksung;Cho, Yun Sung;Jho, Sungwoong;Jun, JeHoon;Kim, Hak-Min;Lim, Jeongheui;Choi, Jae-Pil;Jeon, Sungwon;Blazyte, Asta;Edwards, Jeremy S.;Paek, Woon Kee;Bhak, Jong
    • Molecules and Cells
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    • 제43권1호
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    • pp.86-95
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    • 2020
  • The red-crowned crane (Grus japonensis) is an endangered, large-bodied crane native to East Asia. It is a traditional symbol of longevity and its long lifespan has been confirmed both in captivity and in the wild. Lifespan in birds is known to be positively correlated with body size and negatively correlated with metabolic rate, though the genetic mechanisms for the red-crowned crane's long lifespan have not previously been investigated. Using whole genome sequencing and comparative evolutionary analyses against the grey-crowned crane and other avian genomes, including the long-lived common ostrich, we identified redcrowned crane candidate genes with known associations with longevity. Among these are positively selected genes in metabolism and immunity pathways (NDUFA5, NDUFA8, NUDT12, SOD3, CTH, RPA1, PHAX, HNMT, HS2ST1, PPCDC, PSTK CD8B, GP9, IL-9R, and PTPRC). Our analyses provide genetic evidence for low metabolic rate and longevity, accompanied by possible convergent adaptation signatures among distantly related large and long-lived birds. Finally, we identified low genetic diversity in the red-crowned crane, consistent with its listing as an endangered species, and this genome should provide a useful genetic resource for future conservation studies of this rare and iconic species.

Early overcounting in otoliths: a case study of age and growth for gindai (Pristipomoides zonatus) using bomb 14C dating

  • Andrews, Allen H;Scofield, Taylor R.
    • Fisheries and Aquatic Sciences
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    • 제24권1호
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    • pp.53-62
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    • 2021
  • Gindai (Pristipomoides zonatus) is one of six snappers in a management complex called the Deep 7 of the Hawaiian Islands. Little is known about its life history and a preliminary analysis of otolith thin sections indicated the species may exhibit moderate growth with a lifespan approaching 40 years. Preliminary age estimates from the previous study were reinvestigated using the same otolith sections in an attempt to validate those ages with bomb radiocarbon (14C) dating. From the misalignment of birth years for the otolith 14C measurements with regional references - the post-peak bomb 14C decline period - it was concluded that previous ages were inflated from overcounting of the earliest growth zone structure in otolith sections. The oldest gindai was re-aged to 26 years once the age reading was adjusted for early overcounting, 13 years younger than the original estimate of 39 years for this fish. In general, the earliest otolith growth of gindai was massive and complicated by numerous subannual checks. The approach of lumping the early growth structures was supported by the alignment of 14C measurements from otolith core material (first year of growth). The result was greater consistency of calculated birthdates with the 14C decline reference, along with minor offsets that may indicate age estimation was imprecise by a few years for some individuals. The revised von Bertalanffy growth function applied to the validated age-at-length estimates revealed more rapid growth (k = 0.378 cf. 0.113) and a lifespan of approximately 30 years. The findings presented here are a case study of how the bomb 14C decline period can be used as a tool in the refinement of age reading protocols.