• Journal of Aquaculture
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• v.21 no.2
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• pp.76-81
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• 2008

We investigated the food-effect for ultra-small rotifer Synchaeta kitina cultured under a individual and community by several diets: 3 single trials(Tetraselmis suecica, TET; Isochrysis galbana, ISO; Marine Chlorella ellipsoidea, CHL) and 3 trials with a mixture of 2 species. The rotifer was cultured on the different feeding concentrations. In the individual cultures, the maximum number of offsprings and maximum lifespan of the female investigated to 5.8 inds. and 12.7 days in TET trial, respectively. Values of the developmental phases of the rotifer fed with T. suecica were higher than those of trials without T. suecica. Also it approached faster to maturation level. In the community cultures, the maximum density of TET+CHL trial elevated up to 1,569 inds./mL. But, CHL and ISO showed a poor growth rate and maximum density. The offsprings of the female increased continuously when fed by T. suecica trial, up to $10{\times}10^3$ cells/ind./day. As the quantity of supplied diet was lowered their lifespan were decreased. But, the maximum density and growth rate in the community cultures showed the highest value in the $10{\times}10^3$ cells/ind./day. The efficient food for mass culture of S. kitina was T. suecica, and optimum concentration of their food was 10,000 cells for an individual.

• Journal of Life Science
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• v.22 no.10
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• pp.1428-1433
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• 2012

Longevity is an exciting but difficult subject to study because it is determined by complex processes that require the coordinated action of several genetic factors as well as physiological and environmental influences. Genetic approaches have been applied to animal models to identify the molecular mechanism responsible for longevity. Several experimental model organisms obtained over the last decades suggest that the complete deletion of a single gene by gene targeting has proven to be an invaluable tool for the discovery of the mechanisms underlying longevity. The first discovery of long-lived mutants came from Caenorhabditis elegans research, which identified the insulin/IGF-1 pathway as responsible for longevity in this worm. IGF-1 is a multifunctional polypeptide that has sequence similarity to insulin and is involved in normal growth and development of cells. Several factors in the IGF-1 system have since been studied by gene targeting in the control of longevity in lower species, including nematode and fruit fly. In addition, significant progress has been made using mice models to extend the lifespan by targeted mutations that interfere with growth hormone/IGF-1 and IGF-1 signaling cascades. A recent finding that IGF-1 is involved in aging in mice was achieved by using liver-specific knockout mutant mice, and this clearly demonstrated that the IGF-1 signal pathway can extend the lifespan in both invertebrates and vertebrate models. Although the underlying molecular mechanisms for the control of longevity are not fully understood, it is widely accepted that reduced IGF-1 signaling plays an important role in the control of aging and longevity. Several genes involved in the IGF-1 signaling system are reviewed in relation to longevity in genetically modified mice models.

• Journal of Internet Computing and Services
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• v.16 no.5
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• pp.19-27
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• 2015

Due to the advantages of fast read/write operation and low power consumption, SSD(Solid State Drive) is now widely adopted as storage device of smart phone, laptop computer, server, etc. However, the shortcomings of SSD such as limited number of write operations and asymmetric read/write operation lead to the problem of shortened life span of SSD. Therefore, the block replacement policy of SSD used as cache for HDD is very important. The existing solutions for improving the lifespan of SSD including the LARC scheme typically employ the LRU algorithm to manage the SSD blocks, which may increase the miss rate in SSD due to the replacement of frequently used block instead of rarely used block. In this paper we propose a novel block replacement scheme which considers the block reuse interval to effectively handle various data read/write patterns. The proposed scheme replaces the block in SSD based on the recency decided by reuse interval and age along with hit ratio. Computer simulation using workload trace files reveals that the proposed scheme consistently improves the performance and lifespan of SSD by increasing the hit ratio and decreasing the number of write operations compared to the existing schemes including LARC.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.10
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• pp.493-502
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• 2019

Recently, the installation of renewable energy including PV systems in distribution systems has increased energetically to cope with climate change and energy shortages according to the government's policy of renewable energy 3020. On the other hand, the electrical performance and lifespan of PV modules installed outdoors can be decreased considerably due to a range of deterioration phenomena depending on the ambient environmental factors. To overcome these problems, replacement of degraded PV modules with new ones is increased before the lifespan guaranteed by the makers of PV modules. Therefore, this paper proposes a disposal diagnosis algorithm to evaluate the time interval of the optimal replacement for PV modules according to performance degradation rate of PV modules. In addition, this study modeled an economic evaluation, which is composed of the cost and benefit of PV systems. From the simulation results based on the proposed modeling and algorithm to consider the performance degradation rate specifically, the replacement approach was found to have the best B/C ratio in 10th year with a 3[%] degradation rate and the disposal diagnosis algorithm of PV modules are useful and practical tools for economic evaluations of the replacement of PV modules.

• Journal of Korea Foundry Society
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• v.44 no.1
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• pp.9-15
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• 2024

In this study, in order to improve the lifespan of parts made of manganese steel, manganese steel was cast by varying the amount of Ti added to the steel. In order to confirm the characteristics of the cast material, processing characteristics including tensile and surface characteristics and bearing ratio were investigated. It was confirmed that when the amount of Ti added to high manganese steel exceeds 0.5%, the strength of the alloy is improved due to grain refinement, and fine carbides are formed inside the steel. This results in increased resistance to surface wear compared to the alloy with only Mn added. There was no significant difference in the increase in tensile strength as the Ti content in manganese steel was increased. However, inclusion of Ti showed a small but greater effect on wear resistance compared to Mn, and the size and the distribution of carbides become coarse depending on the Ti content. and was evenly distributed. It was confirmed that the strength and surface properties of manganese steel can be improved by the addition of Ti to improve the lifespan of parts made with this steel. It was found that Ti is effective in developing materials with excellent wear resistance due to refinement of dendrite crystal grains. In the samples where Ti was added, the carbide appears to increase the resistance to surface roughness, and due to the nature of Mn steel, surface hardening begins to occur, which appears to extend the life.

• Toxicological Research
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• v.19 no.3
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• pp.161-172
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• 2003

Explanted mammalian cells perform a limited number of cell division in vitro and than are arrested in a state known as replicative senescence. Such cells are irreversibly blocked, mostly in the G1 phase of cell cycle, and are no longer sensitive to growth factor stimulation. Thus replicative senescence is defined as a permanent and irreversible loss of replicative potential of cells. For this characteristic, replicative senescence seems to evolve to protect mammalian organism from cancer. However, senescence also contributes to aging. It seems to decrease with age of the cell donor and, as a form of cell senescence, is thought to underlie the aging process. Extensive evidence supports the idea that progressive telomere loss contributes to the phenomenon of cell senescence. Telomeres are repetitive structures of the sequence (TTAGGG)n at the ends of linear chromosomes. It has been shown that the average length of telomere repeats in human somatic cells decreases by 30∼200 bp with each cell division. It is generally believed that when telomeres reach a critical length, a signal is activated to initiate the senescent program. This has given rise to the hypothesis that telomeres act as mitotic clocks to regulate lifespan. One proposes that cumulative oxidative stress, mainly reactive oxygen species generated from mitochondria, may mainly cause telomere shortening, accelerating aging. Here, the biological importance and mechanism of replicative senescence were briefly reviewed. Also it was summarized that how oxidative stress affects replicative senescence and telomere shortening.

• Proceedings of the KSR Conference
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• 2011.10a
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• pp.14-21
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• 2011

Reliability means that a product maintains its initial quality and performance at certain period of time(time, distance, cycle etc) under given condition without failure. Given conditions include both environmental condition and operating condition. Environmental condition means common natural environment such as temperature, humidity, vibration, and working condition means artificial environment such as voltage, current load, install place, hours of use, which occurs during using the product. In the field of railway vehicles, although components of railway vehicles with reliability are the trend of mandatory as persisting period of railway vehicles is extended, using components of railway vehicles is insufficient for the practical reliability assessment. but the meaning of the first railway operating agnecy to acquire the parts in the field, the data suggest the reliability of products if you can and can show the reliability of modular units and modular units can provide the reliability of if you can present reliability of the entire system is thought to be here. In this study, lifespan of micro-switch for master controller is analyzed and prediction is performed based on its field data considering the special circumstances of railway vehicles operating agency, such as a large number of trains operates on the same line.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.28 no.5
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• pp.332-337
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• 2015

We have studied the effects of Ag on the characteristics of $Sn_{60}Pb_{40}Ag_x$ (wt%) solder for photovoltaic ribbon. Ag atoms in the solder formed an alloy phase of $Ag_3Sn$ after reacting with some part of Sn atoms, while they did not react with Pb atoms, but decreased the mean size of Pb solid phase. The enhancement of peel strength between solar cell and ribbon is an important part in the developments of long-lifespan solar module. The peel strength of the solder ribbon of $Sn_{60}Pb_{40}$ (wt%) was $169N/mm^2$, and it was largely enhanced by adding a small amount of Ag atoms. The maximum peel strength was $295N/mm^2$ in the solder ribbon of $Sn_{60}Pb_{40}Ag_2$ (wt%). This result is caused by the high binding energy of 162.9 kJ/mol between Ag atoms in the solder and Ag atoms in Ag sheet.

• International journal of advanced smart convergence
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• v.2 no.2
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• pp.19-22
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• 2013

As the demand of the LED for lighting that emits light by p-n junction is increasing, studies on heatproof plate technology is being conducted to minimize the temperature of the LED lighting. As for the temperature of the LED devices, their light emitting efficiency decreases and the maximum lifespan drops down to 1/5. Therefore there are heat dissipation studies going on to minimize the heat. For LED heat dissipation, aluminum heat sink plates are mostly used. For this paper, we designed heat sink that fits residential 20W COB LED Down Light; packaged the heat sink and 20W COB and analyzed and evaluated the thermal properties through a Solidworks flow simulation. We are planning to design the optimal heat sink plate to solve the thermal agglomeration considering TIM(Thermal Interface material).

• Journal of Korean Academy of Nursing
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• v.28 no.2
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• pp.457-467
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• 1998

The purpose of this research was to identify nursing interventions performed by MICU and SICU nurses. For data collection this study used the taxonomy of the Nursing Interventions Classification (NIC : 433 nursing interventions) which was modified by McCloskey and Bulecheck(1996). Each of the 433 interventions were identified as used by MICU and SICU nurses. More than 50% of the ICU nurses performed 280 nursing interventions at least monthly. Rarely used interventions included 26 nursing interventions in the childbearing care class. Overall, both MICU and SICU nurses used interventions in the Physiological : Complex domain most often on a daily basis and the interventions in the Family domain least often. The most frequently reported interventions as being used daily in the MICU were chest physiotherapy, airway suctioning and coughing enhancement and, in the SICU, documentation and airway suctioning. There were significant differences between MICU and SICU nurses in 17 nursing interventions childbearing care, cognitive therapy, communication enhancement, coping assistance, elimination management, lifespan care, health system mediation, immobility management, medication management, neurologic management, patient education, psychological comfort promotion, physical comfort promotion, respiratory management, risk management and information management. The SICU nurses performed there interventions more frequently than the MICU nurses. These findings will help in building of a standardized language for the MICU and SICU and enhance the quality of nursing care.