• 대한의용생체공학회:의공학회지
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• 제41권2호
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• pp.67-74
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• 2020

Brain tumors or gliomas are fatal cancer species with high recurrence rates due to their strong invasiveness. Therefore, the goal of surgery is complete tumor resection. However, the surgery is difficult to distinguish the border because tumors and blood vessels have the same color tone and shape. The fluorescein sodium is used as a fluorescence contrast agent for boundary separation. When the external light source is irradiated, yellow fluorescence is expressed in the tumor, which helps distinguish between blood vessels and tumor boundaries. But, the fluorescence expression of fluorescence sodium depends on the concentration of fluorescein sodium and such analytical data is insufficient. The unclear fluorescence can obscure the boundaries between blood vessels and tumors. In addition, reduce the efficiency of fluorescence sodium use. This paper proposes a protocol of concentration range for fluorescence expression conditions. Fluorescent expression was observed using a near-infrared (NIR) color camera with corresponding dilution using normal saline in 1 ml microtube. The flunoresence emission density range is 1.00 mM to 0.15 mM. The fluorescence emission begin to 1.00 mM and the 0.15 mM discolor. The discolor is difficult to fluorescence emission condition obserbation. Thus, the maximum density range of the bright fluoresecein is 0.15 mM to 0.30 mM. When the concentration range of fluorescein sodium is analyzed based on the gradient of fluorescence expression and the power measurement, the brightest fluorescence is expected to facilitate the complete resection of the tumor. For the concentration range protocol, setting concentration ranges and analyzing fluorescence expression image according to saturation and brightness to find optimal fluorescence concentration are important. Concentration range protocols for fluorescence expression conditions can be used to find optimal concentrations of substances whose expression pattern varies with concentration ranges. This study is expected to be helpful in the boundary classification and resection of brain tumors and glioma.

• 한국약용작물학회지
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• 제26권2호
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• pp.170-180
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• 2018

Background: To obtain useful cosmetic resources, this study aimed to determine the non-saponin fatty acid and inhibitory activities of collagenase and elastase by treatment of Saccharomyces cerevisiae in supercritical fluid extracted oil of the adventitious root culture of wild mountain ginseng. Methods and Results: We performed supercritical fluid extraction at various conditions such as pressure, temperature, time, and use of co-solvents, unlike the n-hexane extraction for the adventitious roots culture of wild mountain ginseng. The non-saponin-fatty acid obtained from the oil of the adventitious roots culture was incresed by treatment with S. cerevisiae. The supercritical fluid extraction was conducted using gas chromatography. Non-saponin-fatty acid content, in the oil of adventitious roots culture of wild mountain ginseng treated with S. cerevisiae for 2 days were three times higher than that in the control. In addition, the oil of the adventitious roots culture treated with S. cerevisiae was investigated for the anti-wrinkle effect by using collagenase and elastase. The oil of adventitious roots culture treated with S. cerevisiae exhibited higher collagenase and elastase inhibitory activities than those in the control. Conclusions: Supercritical fluid extracted oil of the adventitious roots culture of wild mountain ginseng treated with S. cerevisiae was found to have decreased ratio of saturated fatty acids and incresed ratio and content of unsaturated fatty acids increased. Furthermore, it showed anti-wrinkle effects in vitro.

• 정보보호학회논문지
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• 제25권5호
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• pp.1123-1129
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• 2015

모바일 게임의 매크로(자동사냥)는 PC 온라인 게임의 게임봇과 같이 정해놓은 규칙에 의해 화면을 터치하는 프로그램으로서 안드로이드 애플리케이션과 Windows 응용프로그램 등 다양한 형태로 만들어져 사용된다. 이는 정직한 사용자에게 박탈감을 주고 흥미를 잃게 하여 게임을 떠나게 만들고 게임 수명을 단축시킨다. 비록 PC 온라인 게임에서 이러한 부정행위를 막기 위해 다양한 연구가 진행되었으나 모바일 게임은 네트워크 사용이 제한적이고 디바이스의 성능이 PC와 다르기 때문에 동일한 방법을 적용시키기 무리가 있다. 본 논문에서는 터치 이벤트 정보를 이용한 매크로 탐지 프레임워크를 제안한다. 모바일 게임에서 터치 이벤트는 게임을 진행하기 위한 필수적인 제어 명령이다. 매크로는 동일한 패턴으로 화면을 터치하기 때문에 정상적인 사용자들의 패턴과 차이가 있다. 캐쥬얼 게임이 대부분인 모바일 게임에서 터치이벤트는 짧은 시간 동안 매크로와 정상적인 사용자를 구별할 수 있는 가장 좋은 특징이다. 제안한 프레임워크를 활용하여 실제 모바일 게임에서 사용되는 매크로들을 탐지한 결과 100%의 정확도와 0%의 오탐률을 보였다.

• 조형예술학연구
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• 제1권
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• pp.125-164
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• 1999

The Grid, a lattice structure adapted in paintings, is one of thesimplest plastic structures based on the intersection of horizontal and perpendicular lines. Though mankind has, from the pre-history to the present day, put it to good use in everyday life as a traditional practice or a magical, esoteric, religious emblem in the case of the teciform of primitve art, it was in the paintings of Piet Mondrian that the Grid showed its modern, artistic transformation. As we suggest in the title, before I state the Grid as a plastic construction of modern painting, this dissertation inquires the Grid structure that extends over paintings through the ages as a painterly conept, especially focused on their formation and deconstruction. To begin with, my dissertation investigates, as a historical background, a general idea of the geometrical structure and phases of its transition in art, prior to dealing with the Grids as plastic strures in modern painting. the core of my study on formal Grids is permeated through the third chapter. The first chapter concentrates on, firstly, difining the notion of the Grid and geometrical structure, secondly, searching for a historical backgrounb with whict the so- called modern Grid-paintings come in, inquiring into the formation of the illusion-Grid as aresult of discovering the linear perpective and the situation of the conflict and reconciliaton between reality and illusion. Based on these considerations, the second cecond chapter will examine the various sitations of formation and adaptation of the paintery Grids in the Literalism-Grid, as we have already seen in the chapter one. And the cardinal third chapter devotes itself to the process of the formation of the so-called Object-Grid and Literal-Grid in the Literalism or Minimalism as its logical extension of the Painterly Grid. With it we can get to an interpretation and understanding of the meaning and qualites of Grid dwelt in Modernism thst transformed the structure of Painterly Grid originally as a plane concept to the third dimentionl structure. And then, the fourth chapter, we try to draw a new meaning andre-interpretation of the Formal-Grid as a representatuinnal structure appeared in the post-modernist paintings, going with its deconstructional situation. Therefore, we can, in our study on Grids, see the various points of view in the interpretation of them as illusion-structure, as plane-structure, and as cubic-structure; its concept differs form times, oscillating between its formation and deconstruction. The Grid, as we have seen in my dissertation, contains various problems and significations in art that deserve to investigate throughly, including some important plastic problem such as space and plane, and, in the case of do-grid, time. We may expect new concepts of it that will have difference meanings. 1 hope my study makes some contributions to understanding the coordination of the abstruse modern and contemporary art.

• KSBB Journal
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• 제15권3호
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• pp.299-306
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• 2000

발광미생물 (luminescent bacteria)인 P. phosphoreum을 이용한 수계의 환경독성물질로 지정된 ethane, benzene, phenol류에 chlorine이 치환된 l47~의 독성강도를 생체발광의 50%저하시키 는 독성농도인 ECso값을 통한 생물학적 정량을 하였을 때 phenol) benzene) ethane 의 순서로 독성깅도가 높게 산출되 어졌으며, 특히 지환된 chlo괴ne의 수가 증가할수록 독성강도가 강하다는 것을 알 수 있었다. 또한 산출된 ECso값을 이용허여 독성물질들의 물려화학적 parameter특성인 octan이(water 분할계 수 (log P), 용해도 (log S) 및 solvatochromic parameter의 떤관쟁 을 QSAR 모탤링하였으며 실힘을 통하지 않고, 독성의 독성강도 를 예측할 수 있는 회기식을 다음과 같이 산출하였다. $log EC_{50} =2.48 + 0.914 log S(n=9 R2=85.5% RE=0.378) log EC_{50}=0.35 - 4.48 Vi/100 + 2.84 \pi^* +9.46{\beta}m-4.48am (n =14 R2=98.2% RE=0.012) log EC_{50} =2.64 -1.66 log P(n=5, R2=98.8% RE=0.16) log EC_{50}=3.44 -1.09 log P(n=9 R2= 80.8% Re=0.207)$. QSAR 모델은 QSAR 검증식을 통하여 확인된 다중회기식을 이용함으로 실험하지 않은 독성물 질이 갖는 물리화학적인 특성을 대입하여 log Eeso값을 예측할 수 있으므로 경제적, 시간적으로 이익을 얻을 수 있는 모델이다.

• 복식
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• 제56권1호
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• pp.13-31
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• 2006

This study will explore Rococo chinoiserie not only as a prominent style of the decorative arts in general, but also as an important factor that influenced $18^{th}$ century fashions in dress. Two premises support the conclusion of this study. One is that the chinoiserie is truly a hybrid, a totally new style resulting from the mixture of various traditional elements from the East and the West, with little regard for the authentic nature of the original styles. The other is that the geographical scope for defining the chinoiserie influence in the Rococo fashion can be expanded beyond its lexical meaning; the style eventually encompassed visual cues from various Eastern cultures including China, India and Turkey. Regardless of the specific origins, the oriental influences for Rococo fashion can be categorized into two types. The first type is a complete appropriation of structural elements of Eastern clothing, such as pagoda hats, pagoda sleeves, turbans decorated with plumes or fur-trimmed open robes and then combining them with Western dress. These exotic and fancy dress ensembles were worn as masquerades, theatrical costumes or portraits. One extraordinary example is the banyan, a man's dressing gown, which also had a place in everyday life, not just as special costume. Although the banyan became more tailored as time passed, the traditional shape of this Eastern garment was accepted unaltered in the beginning of the $18^{th}$ century. The second type of influence shows in the use of eastern textiles, especially silks, which were made into women's dress. It did not matter to the fashionable lady if her dress was made of the silk produced in China or a European copy of the Chinese original, as long as it satisfied her taste. It is difficult to detect the signs of exotic style from a glance in this type of chinoiserie dresses since it was more ambiguous and conservative adaptation of the oriental influence in Rococo dress styles than the first type. In this study, various oriental influences appearing in $18^{th}$ century Rococo fashions can be defined as part of the chinoiserie style based upon the suggested premises. No matter what the origin of these oriental fashions was, this hybrid of the East and West made one of great impacts on the most frivolous and splendid period of western fashion history.

• ALGAE
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• 제22권4호
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• pp.287-295
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• 2007

Infection of free-living dinoflagellates by endoparasitic dinoflagellates of the genus Amoebophrya are thought to have significant impacts on host population dynamics and have long been proposed to be a potential biological agent for controlling harmful algal bloom (HAB). To understand the impact of Amoebophrya on particular host species, however, it is necessary to quantify aspects the parasites life cycle. Here we used cultures of Amoebophryahost systems from Jinhae Bay, Korea to determine, parasite generation time, and dinospore survival and infectivity. The proportion of host cells infected by Amoebophrya sp. changed sharply from 5% to 87% with increasing dinospore:host inoculation ratios. In the absence of H. triquetra, most free-living dinospores died within 72 hours and their ability to infect host cells decreased remarkably in a day. The relatively short free-living phase of Amoebophrya suggests that the spread of infections is most likely to occur during seasons of high host abundance, as that is when dinospores have the greatest chance of encountering host cells. Infection of host cells inoculated with dinospores during the day was higher than when inoculated during the night, suggesting that infection rates might be related to environmental light conditions and/or diurnal biological rhythm of host species. Total generation times of parasite strains from a thecate dinoflagellate Heterocapsa triquetra were nearly the same regardless of dinospore:host inoculation ratios, representing 54 ± 0.5 h in a 1:1 ratio and 55 ± 1.2 h in a 20:1 ratio. Dinospore production of Amoebophrya sp. infecting Heterocapsa triquetra was estimated to be 125 dinospores per a strain of Amoebophrya sp. There is a growing need to maintain a variety of host-parasite systems in culture and to examine their autecology under various environmental conditions. Such studies would be very helpful in understanding ecological role of these parasites, their overlooked importance in the flow of material and energy in marine ecosystem, and their practical use as biological control agents applied directly to areas affected by HAB.

• 환경영향평가
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• 제23권2호
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• pp.75-87
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• 2014

In order to analyze environmental impact of livestock manure and organic fertilizers, this study investigated livestock-breeding and pollution loads, the status of individual and public livestock manure treatment facilities, and the status of production, supply and components of compost and liquid fertilizers in the Nonsan area. Also, on a trial basis, this study investigated the life cycle of the environmental impact of livestock manure and its organic fertilizers on stream, groundwater, and agricultural soil. The results are as follows. Firstly, were detected the range of $0.13{\sim}1.32{\mu}g/L$ of As, $0.004{\sim}0.467{\mu}g/L$ of Cd and $0.5{\sim}9.2{\mu}g/L$ of Pb as a harmful substances which show lower concentrations than person preservation criteria of water qualities and aquatic ecosystem. However, it is not clear that heavy metals affect environment such as stream, groundwater and agricultural soil. Secondly, this influence could change according to investigation time and treatment efficiency. As were detected large amounts of persistent organic pollutants(e.g. $14.24{\sim}38.47{\mu}g/L$ of acetylsalicylic acid, $1.17{\sim}2.96{\mu}g/L$ of sulfamethazine, and $2.25{\sim}174.09{\mu}g/L$ of sulfathiazole) in effluent from livestock farms and small amounts of sulfathiazole($ND{\sim}1.63{\mu}g/L$) in the stream, it is necessary to monitor POPs at individual and public livestock manure treatment facilities. However, significant environmental impact did not appear at groundwater and agricultural soil in the test area supplied with liquid fertilizers. These results could be applied to investigate the environmental impact of livestock manure through a comprehensive livestock manure management information system.

• 한국식품영양과학회지
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• 제39권12호
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• pp.1846-1853
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• 2010

본 연구에서는 증류수 및 전기분해수인 차아염소산나트륨수와 미산성차아염소산수를 이용한 신선초 세척방법이 녹즙의 저장 중의 일반세균수, pH, 색도, polyphenol 함량, 전자공여능 및 총 항산화력 변화에 미치는 영향을 분석하였다. 녹즙의 저장기간 중 일반세균수는 증류수 세척 방법에서 저장 24시간 만에 식품공전에서 기준치로 제시한 $10^5$ CFU/mL보다 높은 균수를 보인 반면 전기분해수 세척방법에서 저장 4일이 지나도 $10^5$ CFU/mL 이하의 균수가 유지됨을 확인할 수 있었다. 그리고 저장기간 동안 녹즙의 pH 및 색도는 모두 유의적인 차이를 나타내지 않고 일정범위에서 유지되었으며, 녹즙의 항산화성은 polyphenol 함량, 전자공여능 및 총 항산화력 모두 세척방법 간 유사한 결과를 나타내었고, 저장일수가 증가할수록 감소하는 유사한 경향을 나타내어 녹즙의 저장 중 전기분해수에 의한 영향을 나타내지 않았다. 이는 신선초에 대한 전기분해수 세척 방법이 녹즙의 미생물학적 위험은 감소시키면서 품질에는 영향을 나타내지 않는 결과라고 생각되며, 이는 전기분해수 세척 방법이 녹즙의 품질 및 저장성 향상에 기여할 것으로 생각된다.

• 한국위성정보통신학회논문지
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• 제6권1호
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• pp.37-44
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• 2011

2010년 6월 26일에 발사된 통신해양기상위성(천리안)은 Ka-대역 위성통신, 정지궤도 해양관측, 그리고 기상관측을 위한 탑재체를 가지고 있다. 정지궤도상의 위성을 효과적으로 운용하기 위해서 위성 임무운영 개념을 정립하여 이를 위성관제시스템의 개발 초기 단계부터 적용하였다. 천리안 위성의 임무운영은 일별, 주별, 월별 그리고 계절별 운영으로 구분된다. 위성의 일별운영은 임무계획, 명령계획 및 전송, 원격측정 데이터 처리 및 분석, 위성 거리측정 및 궤도결정, 위성의 궤도 및 이벤트 예측, 그리고 휠 오프로딩 파라미터 계산으로 구분된다. 위성의 주별 운영으로는 화요일에 남북방향 위치유지조정, 목요일에 동서방향 위치유지조정으로 구분된다. 월별운영으로는 위성의 온보드 오실레이터를 갱신하기 위한 비행역학 파라미터 계산과 위성으로의 전송이 수행되며 계절별 운영으로 봄과 가을에는 지구가 태양을 가리는 식에 관련된 위성운영을 수행한다. 이 논문에서는 통신해양기상위성이 발사된 후 약 3개월에 걸친 궤도 내 시험 기간 중에 이루어진 위성관제시스템의 주요 기능들에 대한 운영검증을 기술한다. 이 기간 중에 위성관제시스템의 대부분 기능이 성공적으로 검증되었으며 천리안 위성관제시스템은 위성의 설계 수명기간인 7년 또는 위성이 수명을 다하는 그 이후까지 계속 사용될 예정이다.