• Title/Summary/Keyword: life-span effect

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Effect of Korean Red Ginseng Polysaccharide on Lipolytic Action of Toxohormone-L from Cancerous Ascites Fluid (고려홍삼 다당체 성분이 암독소 호르몬-L의 체지방 분해작용에 미치는 영향)

  • 이성동;신유정
    • The Korean Journal of Food And Nutrition
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    • v.8 no.2
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    • pp.110-115
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    • 1995
  • This study was devised to observe the inhibitory effects of ethanol treatment precipitate (crude acidic polysaccharide) from Korean red ginseng on a lipolytic action of Toxohormone-L which has been known as lipolytic and anorexigenic factors. Toxohormone-L was obtained by partial purification of the ascites fluid from mice which had been inoculated with sarcoma-180. The yields of crude acidic polysaccharide from Korean red ginseng was 63.5%. In vitro, at the concentration of 500rg /ml, the inhibition rate of lipolysis by the crude acidic polysaccharide of Korean red ginseng was 38.8% and the total inhibitory activity per gram of ginseng material was 4,928 nit. In vivo, the red ginseng polysaccharide(40mg/ml in saline soon.) 16ul/g of body weight was injected to the sarcoma-180 bearing mice once In 3 days until death. The effects against the extension of life span was little but body weight gain of sarcoma-180 bearing mice decreased significantly by administration of Korean red ginseng polysaccharide compared to those of the control group.

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A Dtudy on the Effect of Polyamines of Korean Red Ginseng on the Growth of Cultured Chichen Embryonic Muscle Cells (홍삼 Polyamine 계 성분이 배양한 계배의 근육세포 성장에 미치는 영향)

  • 구향자;김영중
    • YAKHAK HOEJI
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    • v.31 no.5
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    • pp.296-301
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    • 1987
  • Polyamines of Korean red ginseng were extracted with 5% trichloroacetic acid and purified by ion exchange chromatography using Dowex-50Wx8 resin. Four spots having R$_f$ values of 0.19, 0.28, 0.35, and 0.45 were detected. It was observed under microscopy that those polyamines stimulated the growth and differentiation of chicken embryonic muscle cell. The development of muscle cells from the stage of myoblast to that of myotube was found to be enhanced by those polyamines. It was also observed that those polyamines most likely lengthened, the life-span of the cultured chicken embryonic skeletal muscle cells.

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A Study on Reduced $CO_2$ Emission of Concrete Structures (콘크리트구조물의 이산화탄소배출 저감 기법에 관한 연구)

  • Kim, Ki-Hwan;Song, Ha-Won;Byun, Keun-Ju
    • Proceedings of the Korea Concrete Institute Conference
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    • 2006.11a
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    • pp.897-900
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    • 2006
  • This study concerned the quantification of environmental aggressiveness of concrete structure building up and applied to design of concrete structure. Only the content of carbon dioxide evacuated in the process of fabricating concrete structure was taken as an environmental load and various parameters, for example, material production, transportation, building-up, destruction and reuse were considered. Also, the life span of a concrete structure was taken into account in evaluating the carbon dioxide evolution. Consequently a single equation for the environmental load was obtained, which were subsequently used to assess the effect of high strength/durable concrete structures.

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Rehabilitation af Geriatric Patient (노인환자의 재활)

  • Bae Sung-Soo;Park Rae-Joon
    • The Journal of Korean Physical Therapy
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    • v.2 no.1
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    • pp.95-101
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    • 1990
  • The numbers of older patients increase year by year as the effect of care in illness prolongs the average life span, and it will be quite common to find octogenarians and nonogenarians. The philosophy and technics used in the rehabilitation of older patients are essentially the same as those in general rehabilitation, modified to comply with the physiology of the aging patient. Rehabilitation of the elderly is essentially a matter of teamwork and an attitude of mind. Mo one of us can accomplish a cure by ourselves and there must be confidence and continuing consultation between all members of the team.

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Anticancer Activity of Natural Products including Salvia miltiorrhiza (단삼 등 천연물의 항암작용)

  • 김옥희;정수연;박만기;류항묵;양지선
    • Biomolecules & Therapeutics
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    • v.7 no.1
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    • pp.29-34
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    • 1999
  • The cellular growth inhibition of 20 natural products was screened using SRB (sulforhodamine B) assay against 4 human cancer cell lines(SNU-1, SNU-C$_{4}$, Hep3B, Kato III). Ethanol extracts of Salvia miltiorrhiza, Saussurea lappa and Chelidonium majus showed potent anticancer activity among them, and further, it was fractionated into methylene chloride, hexane and methanol. Methylene chloride and methanol fraction of Salvia radix showed significant inhibitory activity against 4 human cancer cell lines. The effect of Salvia miltiorrhiza on anticancer activity in vitro models was evaluated with methylene chloride fraction of Salvia miltiorrhiza. Life span of ICR mice implanted with sarcoma-180 was increased by 40-61% and BDF$^{1}$ mice implanted with L1210 was increased by 66-89% upon intraperitoneal administration with methylene chloride fraction of Salvia miltiorrhiza. Based on these result, we suggested that Salvia miltiorrhiza showed anticancer activity on the in vivo and in vitro models

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A Study on the Development and Effects of an Educational Program for Ego Integrity of the Elderly through Therapeutic Recreation (치료레크레이션을 활용한 노인자아통합 교육프로그램 개발과 효과에 관한 연구)

  • Hong, Sook-Ja;Lee, Yeung-Eun
    • Korean Journal of Human Ecology
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    • v.17 no.4
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    • pp.623-630
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    • 2008
  • An educational program through therapeutic recreation was developed in order to analyze the effect of enhancement of ego integrity of the elderly. First of all, this study was designed to summarize the concepts of ego integrity and the effects of therapeutic recreation on the elderly and to identify elderly's educational needs of both educational methods and contents from the literature review. The above identified knowledge and information were applied to developing the educational program. The program was composed of 6 sessions with 17 old men and women focused on developing self acceptance using reminiscence on ego integrity through their whole life span and developing positive and active attitudes towards life. And enforcing and evaluation methods were also suggested. The results were as follows. This program showed the significant differences between post-test and pre-test scores in the scale of ego integrity of the elderly. In conclusion, educational program through therapeutic recreation employed for this study has significant effects of increasing ego integrity of the elderly.

A review study of treatment effects for vascular dementia (혈관성 치매 치료 약물에 대한 문헌 고찰 연구 : 외국문헌을 중심으로)

  • Lee, Young-Joon;Han, Chang-Hyun;Jeon, Won-Kyung;Baek, Kyung-Min;Cheon, Woo-Hyun;Choi, Seong-Hun
    • Journal of Society of Preventive Korean Medicine
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    • v.15 no.2
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    • pp.51-67
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    • 2011
  • The average human life span has increased due to the development of modern medicine and science, resulting in prolonged life expectancy and increase in the population counts of the geriatric age group. In particular, a dramatic increase of elderly patients suffering from senile disorders including neurodegenerative diseases, Alzheimer's disease(AD), and vascular dementia has become a serious social problem in public health. Thus, this study is aimed to summarize available clinical trial data on several commonly used medicines include donepezil, rivastigmine, galantamine, memantine and oriental medicine, and examine the effect of oriental medicine combined with western medicine in the treatment of patients with senile disorders using the data from literature reviews and survey studies.

A Study on the Oxide Scale of the Long Term Serviced 12%Cr Boiler Tube Steel (장기간 사용한 12%Cr강 보일러 튜브의 산화스케일에 관한 연구)

  • Kim, Beom-Soo;Min, Taek-Ki
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.24 no.3
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    • pp.281-287
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    • 2012
  • The internal oxide scale of twelve superheater and reheater tubes were tested which were serviced for 30,000~120,000 hours in thermal power plants. The oxide scale was formed in three layers. The Cr-rich area was observed beneath the original metal surface. The hematite ($Fe_2O_3$) phase was formed on the outer surface. The intermediate layer was magnetite ($Fe_3O_4$). The thickness of Cr-rich layer was about half of the total scale. All layers grew during the operation hour of the plant. The thickness of thickest scale was 0.2mm in superheater tubes. This can increase the tube metal temperature about $7^{\circ}C$ more than initial state. $7^{\circ}C$ tube metal temperature can reduce tube life about 30%, but the boiler tube's design margin is big enough therefore it has been analyzed that it would not effect on the life span.

The Effects of Hip Fracture on the Mortality and Activity of Daily Living (고관절 주위 골절이 사망률 및 일상생활 동작에 미치는 영향)

  • Kim, Ho-Bong;Choi, Yong-Own
    • Journal of the Korean Society of Physical Medicine
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    • v.4 no.2
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    • pp.125-131
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    • 2009
  • Purpose:This study performed to evaluate the effect of hip fracture among persons over 50 years old, in Jeju-do, Korea, on mortality, activity of daily living(ADL). Methods:Three hundred eighteen patients over to 50 years of age who lived in Jeju-do and sustained a hip fracture from January 1st 2003 to December 31th 2004 were recruited. The information collected from the hospital records for each patient included age, sex, date of onset, and patients investigated activity grade, ADL, outdoor walking aid on 3month, 6month and 12month. Results:The incidence was 12.5/10,000 for total patients(female 17.0/10,000, male 6.3/10,000) in population over 50 years old. Patients who had lower activity grade and ADL level, showed higher mortality, and patients using outdoor walking aid showed higher mortality. Conclusion:The activity grade, ADL level, Using of outdoor walking aid affect mortality, so more programs about ADL must be developed for the life span and quality of life.

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Recommended properties of elastic wearing surfaces on orthotrotropic steel decks

  • Fettahoglu, Abdullah
    • Steel and Composite Structures
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    • v.18 no.2
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    • pp.357-374
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    • 2015
  • Orthotropic decks composed of deck plate, ribs, cross beams and wearing surface are frequently used in industry to span long distances due to their light structures and load carrying capacities. As a result they are broadly preferred in industry and there are a lot of bridges of this type exist in the world. Nevertheless, some of them cannot sustain the anticipated service life and damages in form of cracks develop in steel components and wearing surface. Main reason to these damages is seen as the repetitive wheel loads, namely the fatigue loading. Solutions to this problem could be divided into two categories: qualitative and quantitative. Qualitative solutions may be new design methodologies or innovative materials, whereas quantitative solution should be arranging dimensions of deck structure in order to resist wheel loads till the end of service life. Wearing surface on deck plate plays a very important role to avoid or mitigate these damages, since it disperses the load coming on deck structure and increases the bending stiffness of deck plate by forming a composite structure together with it. In this study the effect of Elastic moduli, Poisson ratio and thickness of wearing surface on the stresses emerged in steel deck and wearing surface itself is investigated using a FE-model developed to analyze orthotropic steel bridges.