• 한국유통학회지:유통연구
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• 제11권1호
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• pp.99-124
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• 2006

본 연구는 기존의 연구들이 간과했던 점포유형, 제품유형, 가격유형을 고려하여 온라인과 오프라인 유통경로에서 가격수준과 가격편차에는 차이가 있는지를 비교하였다. 즉, 제품특성 및 점포 유형, 배송료, 적립금, 사은품 등과 같은 요인들에 따라서 소비자가 부담하는 총가격이 어떻게 달라지는지, 가격수준, 가격편차, 가격변동 빈도가 어떤 차이가 있는지에 대해서 살펴보았다. 그 결과 온라인 점포의 가격수준이 오프라인 점포보다 더 낮았고, 제품유형(대용량/소용량)에 따라서는 순수온라인 점포에서 소용량 상품의 가격수준이 더 낮았으며, 가격편차는 Hybrid 점포의 가격편차가 더 낮게 나타났다. 가격변동은 Hybrid 점포에서 가장 많이 발생했고, 총가격과 배달가격간의 가격편차는 순수온라인 점포에서 특정상품(화장품)을 제외하고는 총가격 기준의 가격편차가 더 큰 것으로 나타났다. 따라서 가격수준이나 가격편차 등을 고려해 볼 때, 온라인 유통경로가 효율적이거나, 점차 효율적으로 진행되어 가고 있다고 할 수 있었다. 그러나 계절적인 영향이 큰 상품이나, 유통 지배력이 있는 상품의 경우는 순수온라인 생포보다 Hybrid 점포가 더 가격 면에서 효율적인 유통경로로 나타났다.

• Journal of Microbiology and Biotechnology
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• 제19권3호
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• pp.331-337
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• 2009

Interleukin-13 (IL-13) has been proposed as a therapeutic target for bronchial asthma as it plays crucial roles in the pathogenesis of the disease. We developed an in vitro test system measuring transcriptional downregulatory activities on IL-13 as a primary screening method to select drug candidates from natural products. The promoter region of IL-13 (-2,048 to +1) was cloned into the upstream of a luciferase gene in the plasmid pGL4.14 containing the hygromycin resistance gene as a selection marker, generating pGL4.14-IL-13. The EL-4 thymoma and RBL-2H3 mast cells transiently expressing this plasmid highly produced the luciferase activities by responding to PI (PMA and ionomycin) stimulation up to 8-fold and 13-fold compared with the control, respectively, whereas cyclosporin A, a well-known antiasthmatic agent, significantly downregulated the activities. The BF1 clone of RBL-2H3 cells constitutively expressing pGL4.14-IL-13 was established by selecting surviving cells under a constant lethal dose of hygromycin treatment. The feasibility of this system was evaluated by measuring the downregulatory activities of 354 natural products on the IL-13 promoter using the BF1 clone. An extract from Morus bombycis (named TBRC 156) significantly inhibited PI-induced luciferase activities and IL-13 mRNA expression, but not the protein expression. Fisetin (named TBRC 353) inhibited not only PI-induced luciferase activities and mRNA expression, but also the IL-13 protein secretion, whereas myricetin (named TBRC 354) could not suppress the IL-13 expression at all. Our data indicated that this in vitro test system is able to discriminate the effects on IL-13 expression, and furthermore, that it might be suitable as a simple and time-saving primary screening system to select antiasthmatic agents by measuring transcriptional activities of the IL-13 promoter.

• 무역상무연구
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• 제46권
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• pp.29-60
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• 2010

The incentive and reasons to publish FIDIC Conditions of Contract for Design, Build and Operate Projects(DBO Form) are manifold. It is partly a response to the increasing need for sophisticated project delivery methods in both the public and private sectors and the already widespread use of the FIDIC Yellow Book with operation and maintenance obligations and partly a response to the challenge to decrease maintenance cost to a minimum by means of a new procurement route. As a result, FIDIC has developed a new model form to meet this market place requirement. On the other hand, FIDIC did not simply adapt the Yellow Book but has developed a new form from it, whilst preserving the style of the already known FIDIC Forms and maintaining the wording where it was not necessary to change it for the purposes of a DBO Form. Moreover DBO Form fills up supposed gaps in other FIDIC Forms and ameliorates the claim management and dispute management framework. FIDIC DBO approach may be shortly summarized as follows. First, DBO Form provides for single project responsibility. Second, DBO Form has the clear objective of ensuring the use of a most reliable and efficient technology at the lowest life-cycle cost. Third, DBO Form is intended to operate as an effective quality increase in the design and construction of projects. Fourth, DBO Form is intended to provide significant benefits with regard to system integration and reduction of risks. Fifth, DBO Form accelerates and enhances completion schedule compliance. Sixth, DBO takes care of all three supporting pillars of sustainability(including economical, environmental and social elements). DBO Form is obviously a good starting point for negotiations and the preparation of calls for tenders, thus saving the parties time and money. However, existing cultural and legal differences, particular local conditions and the particular needs of some branches of the industry may require the form to be adapted according to the particular needs of a project. And Civil law practitioners are strongly recommended to verify carefully the underlying legal concepts and background of each clause of the General Conditions in order to avoid unnecessary and sometimes unnatural changes and amendments being made. Note that when preparing the Particular Conditions ensure that terminology is consistent and that existing inherent concepts should not be ignored.

• Journal of Nutrition and Health
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• 제30권6호
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• pp.679-689
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• 1997

Nutrition label (NL) on the package of processed food provides consumers with a reliable and consistent source of information . It has been considered as a useful aid for food selection and a potent educational tool for nutrition in daily life. Since current nutrition labeling regulation in Korea does not define a format for presenting nutrition information a wide variety of NL format exists in the markers created by individual manufacturers. Development of standard NL format and its registration remain to be the work for the professionals and government officials. However the acceptance and evaluation of NL by the consumers is a very important and necessary process in the development of NL formats. In this study four different formats A, B, C, D were formulated based on currently circulating labels and new U.S.NL. Subjects used for evaluation of these formats were middle -aged highly educated housewives, who and the potential users of NL. Major parameters observed through the questionnare were their nutritional knowledge of RDA, ability of IC(Information Comparison) and CA (Comprehension and Application of informed nutrient contents), as well as their preference to the different formats. The results are summarized as follows. 1) Of the 178 subjects , 89.9% of the middleaged housewives were college graduates. Their nutrition knowledge of RDA were relatively satisfactory showing over 80% correlation on the basic concepts and unit while for numerical value less than 50% correct answer. 2) IC test scores were significantly different among the formats showing the highest values for format A and B which are presented as absolute value and % RDA, respectively. Format C presented as serving size(number of products) showed the lowest score. CA scores were also significantly different, though the increased load of information did not facilitate to increase the consumers comprehension. 3) RDA knowledge test scores and the scores of IA and CA were correlated in format A and D but not in format B and C suggesting % RDA presentation would be more acceptable to the less educated group. 4) For the preference in the aspects of easiness and time-saving format A was the best one then format D supporting the result of IC and CA test. The results of the present study indicate the most useful and preferred format is the simplest format presented as absolute value without RDA, . The secondly preferred format is the new NL format of the US with much information .

• 한국응용곤충학회지
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• 제45권1호
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• pp.67-74
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• 2006

본 연구는 골프장 잔디 해충의 종합적 관리를 위하여 잔디의 관리 과정 중에 곤충병원성 선충을 투입함으로서 굼벵이 방제의 효율을 향상시키고, 작업 공정을 축소시킴으로서 노동력과 경비를 절감시키며, 환경친화적 방제를 통해 골프장 잔디의 관리자나 이용자들에게 쾌적한 환경을 제공하기 위한 목적으로 수행하였다. 잔디의 예고는 곤충병원성선충의 병원성에 영향을 미쳤는데 꿀벌부채 명나방 유충을 이용한 pot 실험과 등얼룩풍뎅이와 주황긴다리풍뎅이를 이용한 야외실험 모두에서 잔디의 예고가 짧을수록 선충의 방제 효과가 높았다. 통기작업은 곤충병원성 선충의 종에 따라 굼벵이에 대한 병원성에 차이를 보였다. 굼벵이에 대한 병원성이 낮은 곤충병원성 선충은 통기작업과 병행하여 처리하면 병원성이 높아졌으나 병원성이 높은 선충은 큰 차이를 보이지 않았다. 통기작업의 수행시기도 곤충병원성 선충의 병원성에 영향을 미쳤는데 곤충병원성 선충의 처리 전에 잔디에 대한 통기작업을 하는 것이 굼벵이의 방제효과를 높였다. Steinernema carpocapsae 포천 계통 처리 시 등얼룩풍뎅이 유충 밀도 감소율은 선충 처리 전 통기와 선충 처리 후 통기 처리에서 각각 80.4%와 66%를 보여 무통기 처리의 35.4%에 비하여 높았다.

• 한국ITS학회 논문지
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• 제18권6호
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• pp.211-221
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• 2019

우리나라는 자동차 등록대 수 1만 대당 사망자 수는 1.4명으로 여전히 OECD 가입국 중 최하위권에 있으며 교통사고 발생 시 생명과 재산의 보호에 직결되는 신속한 구조 및 대응체계의 필요성이 대두되고 있다. 이에 국토교통부 및 미래창조과학부 다부처 공동 기획 과제로 교통사고 발생 시 자동으로 사고감지 및 관련 정보를 중앙센터로 전송하여 신속하고 정확한 인명구조 등 사고처리가 가능한 차량 ICT 기반 긴급구난체계(e-Call)를 개발하고 있다. 다만, 일반 시민들은 e-Call 서비스의 설치 및 비용적인 측면에서 부정적이다. 이러한 문제를 해결하기 위하여 단말기 보급 활성화를 위한 e-Call의 다양한 도입방식과 효율적인 운영을 위한 센터운영 주체별 운영방식에 대하여 방안을 제시하였다. 또한, e-Call 단말기의 보급률을 예측하여 e-Call 도입에 따른 효과를 분석하였다. 분석결과 e-Call 단말기 도입 시 2022년부터 2031년까지 463~926명 사망자감소 및 3,335~6,669억 원이 절감되는 것으로 나타났다.

• 한국융합학회논문지
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• 제9권7호
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• pp.95-103
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• 2018

본 연구의 목적은 중년층의 노후 준비계획과, 노인장기요양보험제도, 노인장기요양보험제도 내에서 치과의료서비스 분야의 인식도를 확인하고자 하였다. 설문응답대상자들은 노후생활비를 미리 저축하는 비율이 56.1%였으며, 가족들에게 노후 부담을 주기 싫어하는 경향을 나타냈으며,(41.8%) 노후 보살핌은 시설서비스, 간병 제도 등을 이용하고자 하였다. 노인장기요양보험제도에 대해 "조금 알고 있다"는 응답이 36.7%로 나타났다. 또한 장기요양보험제도 내 치과의료서비스의 필요성이 높다고 생각하였다 (98.5%), 만약 서비스가 이루어진다면 참여하겠다고 하는 응답이 92.3%로 나타났으며, 장기요양보험 내 치과의료서비스에 대한 인식 하지 못한 비율이 85.2%로 나타났다. 따라서 노인장기요양보험 내 치과의료서비스부분의 인식 확대가 필요하다. 본 연구결과는 노인장기요양보험 내 치과의료서비스 부분의 추후 제도 개선 시 기초자료로 사용될 수 있을 것으로 사료된다.

• 대한후두음성언어의학회지
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• 제24권2호
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• pp.107-111
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• 2013

Objectives : We developed two-dimensional (2D) scanning videokyomography to evaluate the mucosal wave of whole vocal cords in real time to overcome the limit of preexisting stroboscopy and line scanning videokymography which could not evaluate it. Methods : We implemented a continuous light source with high brightness, a high-definition CMOS camera, and capture board for saving the data. We created the software program to analyze the image data from the system. The test of the functionality of the 2D scanning videokymography camera was performed in one of the authors (P.H.J 32 years old male). Vocal cord images were obtained during normal phonation and falsetto phonation. Images were obtained also during cough, diplophonia. Results : The system made it possible to measure objective parameters, including fundamental frequency, amplitude, regularity, mucosal wave, and phase difference, medial and lateral peak, opening versus closing duration related to vocal fold vibration. Simultaneously, it enabled analysis of the whole mucosal wave of the entire vocal fold in real time. 2D scanning videokymography was also effective for evaluating the dynamic status of the vocal fold when the subject phonated aperiodic voice. Conclusion : In conclusion, 2D scanning videokymography can support the analysis of the whole mucosal wave of the entire vocal cord with objective vocal parameters, overcoming the limitations of stroboscopy and previous line scanning videokymography techniques.

• 한국정밀공학회지
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• 제3권1호
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• pp.40-49
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• 1986

Crack, craze and void are common defects which may be found in the bulk of polymeric materials such as either themoplastics or thermosets. The healing phenomena, autohesion, of these defects are known to be a intrinsic material property of various polymeric materials. However, only a few experimental and theoretical investigations on crack, void and craze healing phenomena for various polymeric materials have been reported up to date [1, 2, 3]. This may be partly due to the complications of healing processes and lacking of appropriate theoretical developments. Recently, some investigators have been urged to study the healing phenomena of various polymenic materials since the significance of the use of polymer based alloys or composites has been raised in terms of specific strength and energy saving. In the earlier published reports [1, 2, 3, 4], the crack and void healing velocity, healing toughness and some other healing mechanical and physical properties were measured experimentally and compared with predicted values by utilizing a simple model such as the reptation model under some resonable assumptions. It seems, however, that the general acceptance of the proposed modeling analyses is yet open question. The crack healing processes seem to be complicate and highly dependent on the state of virgin material in terms of mechanical and physical properties. Furthermore, it is also strongly dependent on the histories of crack, craze and void development including fracture suface morphology, the shape of void and the degree of disentanglement of fibril in the craze. The rate of crack healing may be a function of environmental factors such as healing temperature, time and pressure which gives different contact configurations between two separated surfaces. It seems to be reasonable to assume that the crack healing processes may be divided in several distinguished steps like stress relaxation with molecular chain arrangement, surface contact (wetting), inter- diffusion process and com;oete healing (to obtain the original strength). In this context, it is likely that we no longer have to accept the limitation of cumulative damage theories and fatigue life if it is probable to remove the defects such as crack, craze and void and to restore the original strength of polymers or polymer based compowites by suitable choice of healing histories and methods. In this paper, we wish to present a very simple and intuitive theoretical model for the prediction of healed fracture toughness of cracked or defective polymeric components. The central idea of this investigation, thus, may be the modeling of behavior of chain molecules under healing conditions including the effects of chain scission on the healing processes. The validity of this proposed model will be studied by making comparisons between theoretically predicted values and experimentally determined results in near future and will be reported elsewhere.

• 대한두개안면성형외과학회지
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• 제13권2호
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• pp.85-94
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• 2012

The world's first face transplantation was performed in France, in 2005. Since then, 21 cases of face transplantation have been performed. Face transplantation is one of the most prominent part of composite tissue allotransplantation (CTA) along with hand transplantation. Since these fields are not deal with life-saving organs, there are many arguments about immunosuppression therapy. Recent paradigm of face transplantation shows that surgical ranges are expanded from partial face transplantation to full face transplantation. Most immunosuppression protocols are triple therapy, which consists of tacrolimus (FK-506), mycophenolate mofetil and prednisolone. Anatomical researches, immunosuppression, and immunotolerance take great parts in the researches of CTA. The medical fields directly related to face transplantation are microsurgery, immunology, and transplantation. Nowadays, each field is performed widely. Therefore people, even medical teams think face transplantation could be easily realized, sooner or later. But there are lots of things that should be prepared for not only practice and immunosuppression therapy but also for the cooperation with relevant fields. That's the reason why only 21 cases of face transplantation have been done, while more than 70 cases of hand transplantation have been done in the past years. Especially in Korea, brain death patients are not enough even for organ transplantation and furthermore there are some troubles in taking part in the society of transplantation. Face transplantation has lots of problems concerning variable medical fields, administration, society, ethics, and laws. Therefore, for the realization of face transplantation in Korea, not only medical skills but also political powers are needed.