• Title/Summary/Keyword: life damage

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Correlation Between Fatigue Life of 2.2Ni-0.1Cr-0.5Mo Steel Accompanying Mean Stresses with Cyclic Strain Energy Density (평균응력을 동반하는 2.2Ni-lCr-0.5Mo강의 피로수명과 변형률에너지 밀도와의 상관관계)

  • Koh, Seung-Kee;Ha, Jeong-Soo
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.27 no.1
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    • pp.167-174
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    • 2003
  • Fatigue damage of 2.2Ni-1Cr-0.5Mo steel used fir high strength pressure tubes and vessels was evaluated using uniaxial specimens subjected to strain-controlled fatigue loading. Based on the fatigue test results from different strain ratios of -2. -i 0, 0.5, 0.75, the fatigue damage of the steel was represented by using a cyclic strain energy density. Mean stress relaxation depended on the magnitude of the applied strain amplitude. The high pressure vessel steel exhibited the cyclic softening behavior. Total strain energy density consisting of the plastic strain energy density and the elastic tensile strain energy density described fairly well the fatigue life of the steel, taking the mean stress effects into account. Compared to other fatigue damage parameters, fatigue life prediction by the cyclic strain energy density showed a good correlation with the experimental fatigue lift within a factor of 3.

Convergent Study on Fatigue Life Analysis of Driving Shaft in Jet Engine (제트엔진에서의 추진축의 피로 수명해석에 관한 융합연구)

  • Lee, Jung-Ho;Cho, Jae-Ung
    • Journal of the Korea Convergence Society
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    • v.6 no.6
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    • pp.279-284
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    • 2015
  • The vibration happened at the revolution movement of driving shaft driven with the thrust of airplane affects the great influence on the life of the shaft. And a great loss of life is caused when the fatigue damage is occurred at the driving shaft during revolution. The chattering is occurred at the driving shaft placed at the various revolution due to the aviation environment. Therefore, the part of the driving shaft concerned about the fatigue damage is grasped through the analysis study in this paper. So, the durability to prevent damage can be improved and it is possible to be grafted onto the convergence technique on the basis of a recent safe design and show the esthetic sense.

Cellular Dynamics of Rad51 and Rad54 in Response to Postreplicative Stress and DNA Damage in HeLa Cells

  • Choi, Eui-Hwan;Yoon, Seobin;Hahn, Yoonsoo;Kim, Keun P.
    • Molecules and Cells
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    • v.40 no.2
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    • pp.143-150
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    • 2017
  • Homologous recombination (HR) is necessary for maintenance of genomic integrity and prevention of various mutations in tumor suppressor genes and proto-oncogenes. Rad51 and Rad54 are key HR factors that cope with replication stress and DNA breaks in eukaryotes. Rad51 binds to single-stranded DNA (ssDNA) to form the presynaptic filament that promotes a homology search and DNA strand exchange, and Rad54 stimulates the strand-pairing function of Rad51. Here, we studied the molecular dynamics of Rad51 and Rad54 during the cell cycle of HeLa cells. These cells constitutively express Rad51 and Rad54 throughout the entire cell cycle, and the formation of foci immediately increased in response to various types of DNA damage and replication stress, except for caffeine, which suppressed the Rad51-dependent HR pathway. Depletion of Rad51 caused severe defects in response to postreplicative stress. Accordingly, HeLa cells were arrested at the G2-M transition although a small amount of Rad51 was steadily maintained in HeLa cells. Our results suggest that cell cycle progression and proliferation of HeLa cells can be tightly controlled by the abundance of HR proteins, which are essential for the rapid response to postreplicative stress and DNA damage stress.

Nondestructive Creep Damage Evaluation of High-Temperature Pipelines by Ultrasonic Attenuation Measurement and Electric Resistance Methods (초음파 감쇠 및 전기저항 측정법에 의한 발전소 고온배관의 크리프손상 평가)

  • Lee, In-Cheol;Kil, Du-Song;Gung, Gye-Jo;Cho, Yong-Sang;Lee, Sang-Guk
    • Journal of Ocean Engineering and Technology
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    • v.13 no.3 s.33
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    • pp.100-107
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    • 1999
  • Due to the high temperature and pressure, the materials of pipeline in power plant are degraded by creep damage. So far, many conventional measurement techniques such as replica method, electric resistance method, adn hardness test method for creep damage have been used. Among them, the replica method has mainly been used for the inspection of components. But this technique is restricted to the applications at the surface of the objects and cannot be used to material inside. In this paper, the measuring methods of evaluation by using ultrasonic attenuation and electric resistance for the creep detection of creep damage in the form of cavities on grain boundaries or intergranular microcracks were carried out. Absolute measuring method of quantitave ultrasonic attenuation technique for 1Cr0.5Mo material degradation was analyzed for determining the creep degradation steps using life prediction formula. As a result of measurement for creep specimens, we founded that the coefficient of utrasonic attenuation was increased as the increase of creep life fracton(${phi}c$) and the decreasing rate of wlwctric resistance was also increased.

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Calculation of Fatigue Life of Bow Frame of ARAON Considering Navigating in Ice and Open Waters (빙 및 일반해역 운항을 고려한 아라온호 선수프레임의 피로수명 계산)

  • An, Woo-Seong;Lee, Tak-Kee;Hwang, Mi-Ran
    • Journal of Ocean Engineering and Technology
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    • v.32 no.6
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    • pp.458-465
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    • 2018
  • Ice-going ships such as icebreakers, icebreaking tankers, and icebreaking LNG carriers are subjected to wave loads in open water and ice loads in ice-covered water. In terms of the ship's structural design, the local ice load is important. The fatigue failure due to repeated ice loads is also important. ISO 19906 specifies the assessment of the fatigue limit for a polar offshore structures. In addition, Lloyd's Register refers to fatigue damage based on ShipRight FDA ICE. In ShipRight FDA ICE, the fatigue damage indices due to wave and ice loads are simply presented as 0.5 for each load. It also states that the sum of the two fatigue damage indices should not exceed one. This study calculated and analyzed the fatigue damage index and fatigue life considering ARAON's voyage schedules and the assumed Antarctic voyage based on data measured during the Arctic voyage of ARAON in 2010.

Structural Analysis on Durability of Pedal (페달의 내구성에 대한 구조 해석)

  • Cho, Jae-Ung;Han, Moon-Sik
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.10 no.4
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    • pp.88-95
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    • 2011
  • In this study, the deformation, stress, vibration, fatigue life and the probability of damage are analyzed at the pedal applied by the force of 300N. The maximum stress at the lower of pedal is shown as 20.801MPa. And the maximum displacement is 0.85mm at the maximum response frequency as 3800Hz. Among the cases of nonuniform fatigue loads, 'SAE bracket history' with the severest change of load becomes most unstable but 'Sample history' becomes most stable. In case of 'Sample history' with the average stress of 0 to $-10^{5}MPa$ and the amplitude stress of 0 to $10^{5}MPa$, the possibility of maximum damage becomes 0.6%. This stress state can be shown with 5 times more than the damage possibility of 'SAE bracket history' or 'SAE transmission'. The structural result of this study can be effectively improved with the design of pedal by investigating durability against its damage.

Analysis on Fatigue Fracture at Cam Shaft (캠축에서의 피로파괴해석)

  • Cho, Jae-Ung;Han, Moon-Sik
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.7 no.4
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    • pp.102-108
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    • 2008
  • This study investigates the fatigue life and the damage possibility of cam shaft by the fatigue tool of Ansys. Among nonconstant fatigue loads, the case of 'SAE Bracket History' which is severest at the variation of load tends to be most unstable. The maximum relative damage in case of 'SAE Bracket History' is occurred near the average stress '0' and this case can be shown to have the possibility to take more damage than other cases. The case of 'Sample History' which becomes a little slow at the variation of load tends to be most stable. But there is most damaged possibility of 5% as 7 times at the range of mean stress from 0Pa to -104MPa and amplitude stress from 0MPa to 104MPa than the case of 'SAE Bracket History' or 'SAE Transmission'.

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Study on Fatigue Fracture at Disk Brake (원판브레이크에서의 피로파괴연구)

  • Cho, Jae-Ung;Han, Moon-Sik
    • Transactions of the Korean Society of Machine Tool Engineers
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    • v.18 no.2
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    • pp.201-206
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    • 2009
  • This study investigates fatigue life and possibility damaged at disk brake of automobile by the simulation of fatigue analysis. Among nonconstant fatigue loads, the case of 'SAE Bracket History' which is the severest at the variation of load tends to be most unstable. The case of 'Sample History' which becomes slower at the variation of load tends to be most stable. The value of maximum relative damage in case of 'SAE Bracket History' is occurred near the average stress '0' and this case can be shown to have the possibility to affect more damage than another case. As the result of this study is applied to automobile parts with non constant loads, durability can be improved during drive by preventing any damage.

Genetic Screen for Genes Involved in Chk2 Signaling in Drosophila

  • Park, Suk-Young;Song, Young-Han
    • Molecules and Cells
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    • v.26 no.4
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    • pp.350-355
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    • 2008
  • Chk2 is a well characterized protein kinase with key roles in the DNA damage response. Chk2 is activated by phosphorylation following DNA damage, and relays that signal to various substrate proteins to induce cell cycle arrest, DNA repair, and apoptosis. In order to identify novel components of the Chk2 signaling pathway in Drosophila, we screened 2,240 EP misexpression lines for dominant modifiers of an adult rough eye phenotype caused by Chk2 overexpression in postmitotic cells of the eye imaginal disc. The rough eye phenotype was suppressed by mutation of the ATM kinase, a well-described activator of Chk2. Twenty-five EP modifiers were identified (three enhancers and 22 suppressors), none of which correspond to previously known components of Chk2 signaling. Three EPs caused defects in G2 arrest after irradiation with incomplete penetrance when homozygous, and are likely directly involved in the response to DNA damage. Possible roles for these modifiers in the DNA damage response and Chk2 signaling are discussed.

Effects of the applications of excessive irrigation water and acetaldehyde on Chinese yam tubers at byobusan area of Aomori prefecture in Japan

  • Kawasaki, Michio;Keimatsu, Ryo;Endo, Akira
    • Proceedings of the Korean Society of Crop Science Conference
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    • 2017.06a
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    • pp.247-247
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    • 2017
  • Byobusan area of Aomori prefecture in Japan was a marshy sand dune and had developed for agricultural land use with a large-scale sprinkler system. Recently, it becomes an agricultural problem at this area that distinctive damage with browning maculation and fissures frequently occurs in Chinese yam tubers. Acetaldehyde is one of the factor candidates of underground part damage in plants. In this study, incidence rate of the tuber damage, and the morphological character and elemental composition of the damage parts in tubers were investigated with applications of excessive irrigation water or acetaldehyde water solution into the yam field. The incidence rate of the distinctive tuber damage increased as the input amount of irrigation water was increased. At the browning maculation parts of the tubers, many fissures and damages of cork layer were observed under scanning electron microscopy. In addition, the periderm of tubers was significantly thicker in damaged parts than in non-damaged parts. Funguses, bacterium and nematodes were not observed in the damaged part under scanning electron microscopy. The weight ratio of each constituent element in an analyzed area relative to the total weight of major essential elements was measured with energy dispersive X-ray spectrometry. The results showed that the weight ratios of boron, carbon, phosphorus, sulfur and calcium were higher in damaged parts than in non-damaged parts whereas the weight ratios of oxygen and chlorine were lower in damaged parts than in non-damaged parts. It was also shown by this spectrometry that iron, cadmium, lead and zinc were not directly involved in occurrence of the tuber damage. In this study, there was no remarkable difference of tuber appearance between non-acetaldehyde and acetaldehyde application treatments. From the above results, it is shown that the damage would be a physiological disorder induced by the input of a large quantity of water in the sandy field.

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