• Transactions of the Korean Society of Mechanical Engineers A
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• v.33 no.10
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• pp.1045-1053
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• 2009

Precision stages for 6-DOF positioning, actuated by PZT stacks, which are fed back by gap sensors and guided by flexure hinges, have enlarged their application territory in micro/nano manufacturing and measurement area. The precision stages inherently have such limitations as the nonlinearity between input and output in piezoelectric stacks, feedback signal noise in precision capacitive gap sensors and low material damping in precision kinematic linkages of mechanical flexures. To surmount these limitations, the precision stage is modeled with physics-based variables, which are identified by transient response correspondence, and a gain margin calculation algorithm using the Prandtl-Ishlinskii model and describing function is newly developed to assess system performance more precisely than linear controller design schemes. Based on such analyses, a precision positioning controller is designed. Excellent positioning accuracy with rapid settlement accomplished by the controller is shown in step responses of the closed-loop system.

• Biomolecules & Therapeutics
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• v.28 no.6
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• pp.519-526
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• 2020

Methamphetamine (MA) is one of the most commonly abused drugs in the world by illegal drug users. Addiction to MA is a serious public health problem and effective therapies do not exist to date. It has also been reported that behavior induced by psychostimulants such as MA is related to histone deacetylase (HDAC). MeBib is an HDAC6 inhibitor derived from a benzimidazole scaffold. Many benzimidazole-containing compounds exhibit a wide range of pharmacological activity. In this study, we investigated whether HDAC6 inhibitor MeBib modulates the behavioral response in MA self-administered rats. Our results demonstrated that the number of active lever presses in MA self-administered rats was reduced by pretreatment with MeBib. In the hippocampus of rats, we also found MA administration promotes GluN2B, an NMDA receptor subunit, expression, which results in sequential activation of ERK/CREB/BDNF pathway, however, MeBib abrogated it. Collectively, we suggest that MeBib prevents the MA seeking response induced by MA administration and therefore, represents a potent candidate as an MA addiction inhibitor.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.27 no.1
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• pp.183-193
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• 2003

Micro-weighing device by using null balance method is being essential part in fields of high-technology industries such as precision semiconductor industry, precision chemistry, biotechnology and genetics etc. Also, requirements for high resolution and for large measurement range increase more and more. The performance of the micro-weighing device can be determined by the mechanism design and analysis. The analytical design method has been proposed for the performance improvement such as resolution, measurement range and fast response. The 2-stage displacement amplification is designed to overcome the limit of conventional force transmitting lever. The parallel spring is designed for the measurement result independent of the input force position variation. Also, the natural frequency of mechanism is analyzed for the fast response. After each analysis, optimal design has been carried out. To verify the analysis and design result, characteristics experiments had been carried out after construction. Finally, the system had been controlled.

• Journal of Broadcast Engineering
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• v.10 no.1 s.26
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• pp.68-76
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• 2005

We propose a new type of stereoscopic camera system with a zoom lens module to overcome the backlash for the stability of picture matching and the difficulty of zoom control. This system is designed to control a pair of zoom lens with a rotation lever. In this paper, we present the structural characteristics of our proposed system, and verify that there are no image mismatching at acquired stereo images and the zoom in$\cdot$out is easy to control. In our experiments, we achieve good results that a convergence control is very simple and distortion of images is decreased.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.56 no.1
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• pp.214-221
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• 2007

This paper presents a myoelectric hand prosthesis(MHP) with two degree of freedom(2-DOF), which consists of a mechanical hand, a surface myoelectric sensor(SMES) for measuring myoelectric signal, a control system and a charging battery. The actuation for the 2-DOF hand functions such as grasping and wrist rotation was performed by two DC-motors, and controlled by myoelectric signal measured from the residual forearm muscle. The grip force of the MHP was automatically changed by a mechanical automatic speed reducer mounted on the hand. The skin interface of SMES was composed of the electrodes using the SUS440 metal in order to endure a wet condition due to the sweat. The sensor was embedded with a amplifier and a filter circuit for rejecting the offset voltage caused by power line noises. The control system was composed of the grip force sensor, the slip sensor, and the two controllers. The two controllers were made of a RISC-type microprocessor, and its software was executed on a real-time kernel. The control system used Force Sensing Resistors, FSR, as slip pick-ups at the fingertip of a thumb and the grip force information was obtained from a strain-gauge on the lever of the MHP. The experimental results were showed that the proposed control system is feasible for the MHP.

• Journal of the Korean Society of Marine Environment & Safety
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• v.14 no.4
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• pp.297-301
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• 2008

On-site measurement of ship wave has been carried out in the vicinity of Mokpo inner harbour. The wave data were collected and logged 5Hz by the ultrasonic instrument for 12hour on May 17, 2006. The number of data was 216,000 and the maximum wave height was 81.41cm in normal weather condition. It was found that the wave conditions in this water area are predominantly affected by the ship-generated waved under normal condition. By comparing with the wind-generated waves in the open region which were irregular but with dominant directional characteristics, the existing harbor wave field was much more complex.

• Korean Journal of Human Ecology
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• v.16 no.6
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• pp.1243-1250
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• 2007

The purpose of this study was to compare government guidelines and foreign guidelines related to furniture design for elderly. Future elderly will increasingly accustomed to the provisions of improved housing, education and welfare in comparison with our forebears. Also, there will be upgrading and different need for elderly furniture in our market. The results were as follows. The height of bed was based on the height of wheelchair seat, commonly. A adjustable bed was recommended for abled and disabled elderly. A pull-down shelf, drawer, empty space under chest, folding or sliding door in wardrobe and so on were recommended as a elderly furniture. It were good adjustable sink on human scale. There were need the empty space under sink for wheelchair users, one-touch or lever faucet, etc. There have given a little furniture design guidelines for elderly in Korea until now. But those guidelines haven't been considered enough human scale of elderly including wheelchair user. Because the close investigations have not made about abled and disabled elderly for their furniture design. So first of all, the government should be examined elderly physical size more accurately for elderly furniture design. The guideline for elderly furniture design should be for abled elderly and the disabled, too.

• Proceedings of the PSK Conference
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• 2002.10a
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• pp.316.3-317
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• 2002

In previous reports, we exhibited that acteoside showed significant cytotoxicity against various cancer cells. In this study we investigated that acteoside is capable of inducing differentiation in HL -60 human leukemia cell line. After being treated with acteoside, the growth curve was decreased remakably in a dose- and time-dependent manner, and cell doubling time was delayed. Exposure of cells to 20 $\mu\textrm{g}$/m$\ell$ acteoside induced differentiation of HL-60 cells to monocyte/macrophage-like cells by cell surface antigen expression. The percentage of NBT reducing activity was increased in a time-dependent manner. In addition. the protein lever of p21 and p16 increased and ppRb decreased in western biot analysis. Theas results suggest that acleoside possess the activity of inducing differentiation in HL-60 cells.

• Journal of the Korean Society for Railway
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• v.9 no.2 s.33
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• pp.230-236
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• 2006

For a short-term measurement to reduce an accident on a railroad crossing, it is necessary to find out the weakness and problems of existing equipment in the railroad transportation system. The analysis of railroad crossing accidents shows that main causes of accidents (24.9%) are the careless driving including an engine problem, damage on the safety equipment, slide on the snow, and an engine stop on the railroad crossing. Therefore, it is required to install a sensor, or to make a crossing gate at the exist for detecting obstacles on a railroad to prevent collisions among trains. This paper suggests 'a panel sensor using the strain gauge' to make up the weaknesses of the sensing Dead Zone, which are caused by using a laser method, and to detect any small objects passing railroads in order to reduce the errors, which are occurred in the earth magnetic field for controlling Exit Slide Crossing Arm Detector. The device, suggested in this paper, is verified with detecting any small objects passing the railroad, with judging entry decision clearly, and with controlling passing gate and obstruction warnings/cautions obstacles at the same time, through an experimental test.

• Journal of the Korean Home Economics Association
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• v.12 no.1
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• pp.459-471
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• 1974

This study was carried out on the thermal transmission on account of variation of weaves and researched on the selection of the most suitable weaves for warmth. Also the interrelation among the density, thickness and thermal transmission by different weaves was studied, the author has woven three fundamental weaves, five weaves derived from the fundamental weaves and two special weaves for the purpose of experiment. In weaving of fabrics for experiments the lever type hand loom was used. Testing of texture was carried out according to KS and ASTM. The thermal transmission was also tested by as cooling method which were developed by the author. The conclusions of experiments were as follows. 1. Matt weaves, honey comb weaves and satin weaves having long floating yarns have large cover factor and were thicker. these structures of the weaves were good in warmth. 2. Thermal transmission was reciprocated to the cover factor, thickness and value of cover factor multiplied by thickness : It was found that the weaves of woven fabrics for warmth had better use of satin weaves, Matt weaves, Granite weaves and Honey comb weaves. In the time of warmth is not the first purpose, had better use of Rib weaves. Plain weaves and Twill weaves with thin thickness and high thermal transmission.