• 대한의생명과학회지
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• 제14권1호
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• pp.59-62
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• 2008

This experiment was performed to study the effect of TSH (thyroid-stimulating hormone) on the expression of endoplasmic reticulum (ER) chaperones in the rat thyrocytes FRTL-5 cells. Although the expressions of ER membrane kinases (ATF6, IRE1 and PERK) were specially enhanced under absence of TSH, no remarkable up- or down regulations of ER chaperones (BiP, CHOP and Calnexin) were detected by TSH. We firstly report here that TSH by dose up-regulated expression of ER membrane kinases in FRTL-5 culture thyrocytes.

• 대한수학교육학회지:수학교육학연구
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• 제12권3호
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• pp.353-369
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• 2002

In this paper, we deal with the teaching of the approaching to algebra based on patterns. The change of algebra curriculum has been undergoing in many countries including USA, England, Australia. The traditional algebra curriculum starts with letters(variables), algebraic expressions, and equations. But these formal approaching method has many difficulties in teaching school algebra. Therefore the new algebra curriculum has to be needed, and the approaching to algebra based on patterns has been focused. In this paper, we compare this new approaching to algebra based on patterns to the traditional algebra curriculum. Next we consider the NCTM algebra curriculums based on Standards (1989) and Standards 2000(2000), Britannica textbook series(1998) based on RME. Also we investigate our pattern approaching in our curriculum and discuss some problems from the perspective of the approaching to algebra based on patterns.

• 한국전통조경학회지
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• 제30권2호
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• pp.142-154
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• 2012

옛 부안 관아(官衙)터 반석(磐石)위에, 19세기 초 현감 박시수가 쓴 초대형 초서체 바위글씨 '봉래동천(蓬萊洞天) 주림(珠林) 옥천(玉泉)'의 의미는 혜천지역의 바위글씨와 맞물려 이 일대가 곧 신선의 세계임을 반증하고 있다. 바위글씨가 집중된 상소산 아래 서림(西林)과 금대(琴臺)그리고 혜천(惠泉)등 경물 지칭의 바위글씨는 이 고장 출신으로 여류시인이자 관기(官妓)였던 이매창이 교우했던 인물들과 밀접한 관련성을 보이며, 이곳이 부안의 풍류와 선비정신이 교융(交融)된 지역 명소이자 정원 후원으로서의 역사성을 배태한 장소임을 상징한다. 이 지역 바위글씨의 대부분은 19세기부터 20세기 초반에 걸쳐 각자된 것으로, 총 34건 중 경물(景物)관련 4건, 경색(景色) 관련 8건, 인명(人名)관련 5건 그리고 시문(詩文)15건, 기타 2건 등으로 분류되었고, 전체적으로 시문의 비율이 월등히 높았으며, 시문 속 주제어의 중심에는 '상소산'과 '혜천'이 자리 잡고 있다. '봉래동천'은 물론 '소산사호(蘇山四皓)'의 표현이나 연단로에서 제조된 신선의 단약에 비견되는 '혜천의 샘물'은 신선사상의 영향이 강하게 누적되고 관성화되어 착근된 장소정체성의 단면을 보여주는 경관어휘이자 봉래동천, 주림과 옥천 바위글씨의 조합과 조응하는 것으로 이 일대가 '신선의 세계'임을 상징화하고 있다. 헌종11년(1845년)현감 조연명의 인위적인 식수 이후, 체계적으로 가꾸어온 숲인 서림과 그 숲에 조성된 정각 서림정과 주변에 산재한 '혜천 금대'등 바위글씨가 새겨진 암반 등은 신선사상이 깃든 관아(官衙)의 후원이자 임천정원(林泉庭苑)으로서의 성격과 면모를 보여주는 흔적이며, 이곳에 깃든 장소정체성의 핵심이다. 또한 낙토(樂土), 부안의 중심인 관아지역과 풍류 시회처(詩會處)로서 후원 혜천지역은 선계 동경적 아취와 상상력을 바탕으로 생활 속의 공간으로 구현 정착되어 왔음을 볼 때, '상소산과 서림'그리고 '동천과 혜천'의 관련성과 상징성이야말로 이곳 장소정체성의 본질이라 할 만하다. 내변산과 격포지역이 부안관광의 중심인 현실을 볼 때, 서림공원 일대의 바위글씨를 중심으로 한 문화유적은 부안의 대표적인 관광명소이자 부안 읍치를 대표하는 역사문화경관으로 자리매김하기를 기대한다.

• 한국정보과학회논문지:컴퓨팅의 실제 및 레터
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• 제11권3호
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• pp.284-291
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• 2005

본 연구에서는 학습한 표정 패턴을 기반으로 비디오에서 사람의 얼굴을 검출하고 표정을 분석하여 분류하는 프레임워크를 제안한다. 제안 프레임워크는 얼굴 표정을 인식하는데 있어 공간적 정보 외시간에 따라 변하는 표정의 패턴을 표현하기 위해 표정 특성을 공간적으로 분석한 PCA와 시공간적으로 분석한 Hidden Markov Model(HMM) 기반의 표정 HMM을 이용한다. 표정의 공간적 특징 추출은 시간적 분석 과정과 밀접하게 연관되어 있기 때문에 다양하게 변화하는 표정을 검출하여 추적하고 분류하는데 HMM의 시공간적 접근 방식을 적용하면 효과적이기 때문이다. 제안 인식 프레임워크는 현재의 시각적 관측치와 이전 시각적 결과간의 사후 확률 방법에 의해 완성된다. 결과적으로 제안 프레임워크는 대표적인 6개 표정뿐만 아니라 표정의 정도가 약한 프레임에 대해서도 정확하고 강건한 표정 인식 결과를 보인다. 제안 프레임 워크를 이용하면 표정 인식, HCI, 키프레임 추출과 같은 응용 분야 구현에 효과적이다

• 대한의생명과학회지
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• 제10권4호
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• pp.385-389
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• 2004

A novel gene Jpk, originally isolated as a trans-acting factor associating with the position-specific regulatory element of murine Hox gene has been reported to be expressed differentially in the liver of diabetic animals. Therefore, in an attempt to develop a possible diagnostic marker and/or new therapeutic agent for the Diabetes Mellitus, we analysed the expression pattern of Jpk among organs of normal and diabetic Sprague-Dawley (SD) rats. Total RNAs were isolated from each organs (brain, lung, heart, liver, spleen, kidney, muscle, blood, and testis) of diabetic and normal rats in both normal feeding and after fasting condition. And then RT (reverse transcription) PCR has been performed using Jpk­specific primers. The Jpk gene turned out to be expressed in all organs tested, with some different expression profiles among normal and diabetes, though. Upon fasting, Jpk expressions were reduced in all organs tested except kidney, muscle and brain of normal rat. Whereas in diabetes, Jpk expressions were increased in all organs except heart, muscle and testis when fasted. Compared to the normal rat, the Jpk expression level in blood was remarkably upregulated (about 15-30times) in diabetic rat whether in normal feeding or fasting conditon, suggesting that the Jpk could be a candidate gene for the possible blood diagnostic marker for the Diabetes Mellitus.

• Imaging Science in Dentistry
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• 제51권3호
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• pp.279-290
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• 2021

Purpose: Using images in the facial image comparison process poses a challenge for forensic experts due to limitations such as the presence of facial expressions. The aims of this study were to analyze how morphometric changes in the face during a spontaneous smile influence the facial image comparison process and to evaluate the reproducibility of measurements obtained by digital stereophotogrammetry in these situations. Materials and Methods: Three examiners used digital stereophotogrammetry to obtain 3-dimensional images of the faces of 10 female participants(aged between 23 and 45 years). Photographs of the participants' faces were captured with their faces at rest (group 1) and with a spontaneous smile (group 2), resulting in a total of 60 3-dimensional images. The digital stereophotogrammetry device obtained the images with a 3.5-ms capture time, which prevented undesirable movements of the participants. Linear measurements between facial landmarks were made, in units of millimeters, and the data were subjected to multivariate and univariate statistical analyses using Pirouette^® version 4.5 (InfoMetrix Inc., Woodinville, WA, USA) and Microsoft Excel^® (Microsoft Corp., Redmond, WA, USA), respectively. Results: The measurements that most strongly influenced the separation of the groups were related to the labial/buccal region. In general, the data showed low standard deviations, which differed by less than 10% from the measured mean values, demonstrating that the digital stereophotogrammetry technique was reproducible. Conclusion: The impact of spontaneous smiles on the facial image comparison process should be considered, and digital stereophotogrammetry provided good reproducibility.

• 디자인학연구
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• 제14권4호
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• pp.99-108
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• 2001

부적에는 고대의 다양한 기호나 그림, 원형문자가 사용되어 왔으며 현재도 쓰여지고 있다. 이는 체계화된 문자와 조합되어 다양한 표현으로 메시지를 전달하고 있으며, 현재도 전통적인 방법이 고수되는 반면 지속적인 변화를 통해 인간의 감정과 욕망을 표현하고 있다. 부적은 일반적 견해로 생각하는 실험 타이포그래피 만큼이나 논리적이며 실험적인 성격이 강하다. 또한 문자가 가지고 있는 의미로 다른 기호나, 상형문자, 그림 및 유사단어로 표현하고 있다. 각각의 요소들은 상징적 심볼 및 연상성, 글의 해체성 등 다양성을 갖추고 있었다. 이러한 타이포그래피의 실험적 성격을 더욱 실험적으로 표현가능성을 보여 주고 있는 부적에서 배워야할 해체와 구성작업을 회화적 타이포그래피 관점으로도 눈여겨볼 점이 많았음이 관찰되었다. 본 연구는 부적이 가지고 있는 조형적 특징을 실험 타이포그래피와 비교, 분류, 분석하여 부적이 가지고 있는 조형적 특징이 시각적 언어와 타이포그래피 표현으로 응용될 수 있는 가능성을 살펴보고자 한다. 또한, 한국적 조형 문화로서 부적이 형태적 물성이 가지는 시각 이미지에 대한 재인식과 그 가능성에 대한 모색은 타이포그래피의 서구적인 고정된 틀을 벗어나 우리의 문화와 정서에 맞는 타이포그래피의 표현 영역을 화장하는 것이 앞으로의 과제라 할 수 있다.

• 한국수학교육학회지시리즈A:수학교육
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• 제50권2호
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• pp.213-231
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• 2011

The purpose of this study is to analyze the 6th graders' understanding of the concepts of variable on various aspects of school algebra. For this purpose, the test of concepts of variable targeting a sixth-grade class was conducted and then two students were selected for in-depth interview. The level of mathematics achievement of the two students was not significantly different but there were differences between them in terms of understanding about the concepts of variable. The results obtained in this study are as follows: First, the students had little basic understanding of the variables and they had many cognitive difficulties with respect to the variables. Second, the students were familiar with only the symbol '${\Box}$' not the other letters nor symbols. Third, students comprehended the variable as generalizers imperfectly. Fourth, the students' skill of operations between letters was below expectations and there was the student who omitted the mathematical sign in letter expressions including the mathematical sign such as x+3. Fifth, the students lacked the ability to reason the patterns inductively and symbolize them using variables. Sixth, in connection with the variables in functional relationships, the students were more familiar with the potential and discrete variation than practical and continuous variation. On the basis of the results, this study gives several implications related to the early algebra education, especially the teaching methods of variables.

• Carbon letters
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• 제22권
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• pp.42-47
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• 2017

In this paper, the in vitro biocompatibility of graphene film (GF) with osteoblasts was evaluated through cell adhesion, viability, alkaline phosphatase activity, F-actin and vinculin expressions, versus graphite paper as a reference material. The results showed that MG-63 cells exhibited stronger cell adhesion, better proliferation and viability on GF, and osteoblasts cultured on GF exhibited vinculin expression throughout the cell body. The rougher and wrinkled surface morphology, higher elastic modulus and easy out-of-plane deformation associated with GF were considered to promote cell adhesion. Also, the biomineralization of GF was assessed by soaking in simulated body fluid, and the GF exhibited enhanced mineralization ability in terms of mineral deposition, which almost pervaded the entire GF surface. Our results suggest that graphene promotes cell adhesion, activity and the formation of bone-like apatite. This research is expected to facilitate a better understanding of graphene-cell interactions and potential applications of graphene as a promising toughening nanofiller in bioceramics used in load-bearing implants.

• 복식
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• 제41권
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• pp.153-168
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• 1998

The purpose of this study is to examine, specifically, the external and internal characteristics of anti-fashion expression in the Korean student movement after the 1945 Liberation. The dress expressed in the student movement represented the purity of student and characterized resistance, and this character expressed strongly in 80s, faded from middle of 90s. Until the 60s, the student movement was not characterized by, so activist students wore dress and suits. It symbolized students as an elite group of society. They added on head-bands to express resistance. In the 70s, activist students wore school uniforms, school military training wear, blue jeans and loose shirts in demonstrations. They tried to express re-bellion against the government and the older gen-eration. In the 80s, the period was remarkably distingusihing by the economic growth at that time. Activist students wore T-shirts with Korean letters and popular paintings specially made, Korean costumes, wrapped in the Taggeuki (Korean national flag), and refused wear on jeans because of anti-Americanism. They also wore masks, muffled their faces, and got their heads shaved. These anti-fashions are very strong expressions for the national independence spirit, national traditional heitage, anti-foreign power and anti-American. In the early 90s, activist students wore reformed Korean costumes specially made group uniforms, after that they wore casual everyday clothes with caps. They tried to express remarkable resistance in the early 90s, but after the mid-90s expression of resistance weakened and faded, so there was no distinction between activist and non-activist. There are the reasons why the student movement changed after the peaceful transfer of political power.