• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2004.11a
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• pp.169-174
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• 2004

To design ship channel is one of important factors for planning and developing a port. In most case, the core factors for designing ship channel are the layout and width of dvnnel provided the net underkeel clearance is assessed as safety. In this study, Variable Bumper Area(VBA) model is applied to design and assess ship channel. This model reflects ship's principle dimension, ship domain theory, ship speed, conning officer's ship handling skill and experience and all external forces which cause leeway, set and drift and the change of ship maneuvering characteristics. Full Mission Ship Handling Simulator is used to analyze ship dynamic data according to conning officer's ship control, external forces, etc. This model uses Domain-index for assessing the efficiency and safety of the channel. The proposed model is applied to Ulsan new port plan which has a channel width of 1.5 times the length if the largest vessel, a radius if 5 times the length of the largest vessel in a curve of 57 degree centerline angle and SBM facility adjacent to the lateral edge if channel. The result of this study shows tint the width and radius of channel curve are suitable for the target ship but the difficulty of ship handling is caused by the large course change and SBM located in the vicinity if channel.

• Horticultural Science & Technology
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• v.16 no.1
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• pp.27-29
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• 1998

Artificial pollination (AP) and gibberellin A4+7 plus benzyladenine (promalin) were applied alone and together. AP was applied at 10% flowering time with 'Senshu' pollen (Malus domestica cv. Senshu). 12mg/L promalin was applied at 0, 10 and 20 days after falling of central flowers, respectively. In promalin treatment with or without AP application methods, fruit length, weight and length/diameter (L/D) were higher than those of control and AP. However, in AP and AP+ promalin application, the number of seeds and seed weight were higher than those of control and promalin. In AP+ promalin treatment, 78.6% fruits showed their uniform fruit shape and so significantly enhanced fruit uniformity compared to other treatments. Also cortex and core thickness of fruits were greater at the apex than that of other treatment. Fruit with L/D ratio over 0.87 were highly produced by applications of AP+promalin and promalin than control and AP only. 'Fuji' apples in good shape can be produced by using of AP + promalin together.

• Biomolecules & Therapeutics
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• v.29 no.3
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• pp.282-289
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• 2021

A novel coronavirus, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), caused a worldwide pandemic. Our aim in this study is to produce new fusion inhibitors against SARS-CoV-2, which can be the basis for developing new antiviral drugs. The fusion core comprising the heptad repeat domains (HR1 and HR2) of SARS-CoV-2 spike (S) were used to design the peptides. A total of twelve peptides were generated, comprising a short or truncated 24-mer (peptide #1), a long 36-mer peptide (peptide #2), and ten peptide #2 analogs. In contrast to SARS-CoV, SARS-CoV-2 S-mediated cell-cell fusion cannot be inhibited with a minimal length, 24-mer peptide. Peptide #2 demonstrated potent inhibition of SARS-CoV-2 S-mediated cell-cell fusion at 1 µM concentration. Three peptide #2 analogs showed IC50 values in the low micromolar range (4.7-9.8 µM). Peptide #2 inhibited the SARS-CoV-2 pseudovirus assay at IC50=1.49 µM. Given their potent inhibition of viral activity and safety and lack of cytotoxicity, these peptides provide an attractive avenue for the development of new prophylactic and therapeutic agents against SARS-CoV-2.

• Earthquakes and Structures
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• v.16 no.3
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• pp.295-310
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• 2019

This study attempts to develop new simplified approximate formulas to predict the fundamental natural periods of vibration (T) for bearing wall systems engaged with special reinforced concrete shear walls (RCSW) under seismic loads. Commonly, seismic codes suggested empirical formulas established by regression analysis of measured T for buildings during earthquake motions. These formulas depend on structure type, building height, number, height and length of SW, and ratio of SW area to base area of structure. In this study, a parametric investigation is performed for T of 110 selected models of bearing RCSW systems with varying structural height, configuration of horizontal plans including building width, number and width of bays, presence of middle corridors and core SWs. For this purpose, a 3D non-linear response time history (TH) analysis is implemented using ETABS v16.2.1. New formulas to estimate T are anticipated and compared with those obtained from formulas of IBC 2012 and ASCE/SEI 7-10. Moreover, the study examines responses of an arbitrarily two selected test model of 60 m and 80 m in height with presence of SWs having middle corridors. It is observed that the performance of the tested buildings is different through arising of considerable errors when using codes' formulas for estimating T. Accordingly, using the present proposed formulas exhibits more reasonable and safer design compared to codes' formulas. The results showed that equitable enhancement is promising to improve T formulas approaching enhanced and accurate estimation of T with reliable analysis, design, and evaluation of bearing RCSW systems.

• Steel and Composite Structures
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• v.44 no.3
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• pp.309-324
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• 2022

The post-fire elastic stiffness and performance of concrete-filled steel tube (CFST) columns containing recycled aggregate concrete (RAC) has rarely been addressed, particularly in terms of material properties. This study was conducted with the aim of assessing the modulus of elasticity of recycled aggregate concrete-filled steel tube (RACFST) stub columns following thermal loading. The test data were employed to model and assess the elastic modulus of circular RACFST stub columns subjected to axial loading after exposure to elevated temperatures. The length/diameter ratio of the specimens was less than three to prevent the sensitivity of overall buckling for the stub columns. The gene expression programming (GEP) method was employed for the model development. The GEP model was derived based on a comprehensive experimental database of heated and non-heated RACFST stub columns that have been properly gathered from the open literature. In this study, by using specifications of 149 specimens, the variables were the steel section ratio, applied temperature, yielding strength of steel, compressive strength of plain concrete, and elastic modulus of steel tube and concrete core (RAC). Moreover, parametric and sensitivity analyses were also performed to determine the contribution of different effective parameters to the post-fire elastic modulus. Additionally, comparisons and verification of the effectiveness of the proposed model were made between the values obtained from the GEP model and the formulas proposed by different researchers. Through the analyses and comparisons of the developed model against formulas available in the literature, the acceptable accuracy of the model for predicting the post-fire modulus of elasticity of circular RACFST stub columns was seen.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2005.11a
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• pp.17-20
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• 2005

This study investigates mock-up test of the concrete containing crushed sands with improved quality and following could be draws as conclusions. The slump satisfies the target value. The air content reaches the goal, however, it decreases by the occurrence of loss with elagse of age. In normal strength region, the setting time of CS24 member is shorter than that of SS24 member. In high strength region, the setting time of SS50 member is make only slower than that of CS5O because of the use of retarding AE agent. The compressive strength of the concrete using crushed sands is little higher than the concrete using washed sea sands, and the compressive strength of core sample increases at lower part. Drying shrinkage of the concrete using crushed sands is larger than that using washed sea sands. At water caring condition, both the concrete using crushed sands and using washed sands expand at first, exhibit to be swelled and with elagse of age, they remain relatirely constant. Also, the drying shrinkage occurred greatly when the width and thickness of a member are small because it is easy to evaporate the inner part vapor in the small width and thickness of a member. there can be little different according to the location of a contact gauge, however it is similar to the change of specimen's length change. The concrete using crushed sands, of which grading, grain shape and fine particle is improved, are comparable to the quality of the concrete using washed sea sand.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.6
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• pp.3555-3559
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• 2013

Chronic hepatitis B virus (HBV) infection and dietary exposure to aflatoxin B1 (AFB1) are major risk factors for hepatocellular carcinoma (HCC). The aim of this study was to evaluate the role of HBV genetic variation and the R249S mutation of the p53 gene, a marker of AFB1-induced HCC, in Thai patients chronically infected with HBV. Sixty-five patients with and 89 patients without HCC were included. Viral mutations and R249S mutation were characterized by direct sequencing and restriction fragment length polymorphism (RFLP) in serum samples, respectively. The prevalences of T1753C/A/G and A1762T/G1764A mutations in the basal core promotor (BCP) region were significantly higher in the HCC group compared to the non-HCC group. R249S mutation was detected in 6.2% and 3.4% of the HCC and non-HCC groups, respectively, which was not significantly different. By multiple logistic regression analysis, the presence of A1762T/G1764A mutations was independently associated with the risk of HCC in Thai patients.

• Journal of Information Technology Services
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• v.18 no.3
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• pp.17-35
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• 2019

Call centers do not simply play a role of responding to customers' calls, but they have developed into a core unit for maintaining competitiveness through services, marketing, or sales. Since the service quality of call centers heavily affects customer satisfaction, organizations have focused on enhancing it by reducing waiting time and increasing service level. One of the techniques, which improve the service quality of call centers, is to employ multi-skilled agents that can handle more than one type of calls. This study deals with three issues relevant to multi-skilled agents. First, we analyze how the way of allocating a specific group of agents to a set of skills affects the performance of call centers. Secondly, we investigate the relationship between the number of multi-skilled agents and the performance of call centers. Finally, we examine the impact of agent selection rules on the performance of call centers. Two selection rules are compared : the first rule is to assign a call to any available agent at random while the other rule is to assign a call preferably to single-skilled agents over multi-skilled agents when applicable. Based on simulation experiments, we suggest three implications. First, as the length of cycles in the agent-skill configuration network becomes longer, call centers achieve higher service level and shorter waiting time. Secondly, simulation results show that as the portion of multi-skilled agents increases, the performance of call centers improves. However, most of the improvement is attained when the portion of multi-skilled agents is relatively low. Finally, the agent selection rules do not significantly affect the call centers' performance, but the rule of preferring single-skilled agents tends to distribute the workload among agents more equally.

• Proceedings of the Korean Society of Crop Science Conference
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• 2017.06a
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• pp.342-342
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• 2017

Rice seeds are a home to endophytic bacterial communities which serve as a source of the plant's endophytes. As rice undergo physiological and adaptive modifications through cross breeding in the process of attaining salinity tolerance, this may also lead to changes in the endophytic bacterial community especially those residing in the seeds. This study explores the community structure of seed bacterial endophytes as influenced by rice parental lineage, genotype and physiological adaptation to salinity stress. Endophytic bacterial diversity was studied through culture dependent technique, cloning and Terminal-Restriction Fragment Length Polymorphism (T-RFLP) analysis. Results revealed considerably diverse communities of bacterial endophytes in the interior of rice seeds. The richness of ribotypes ranges from 5-14 T-RFs corresponding to major groups of bacterial endophytes in the seeds. Endophytic bacterial diversity of the salt-sensitive IR29 is significantly more diverse compared to those of salt-tolerant cultivars. Proteobacteria followed by Actinobacteria and Firmicutes dominated the overall endophytic bacterial communities of the indica rice seeds based on 16S rDNA analysis of clones and isolates. Community profiles show common ribotypes found in all cultivars of the indica subspecies representing potential core microbiota belonging to Curtobacterium, Flavobacterium, Enterobacter, Xanthomonas, Herbaspirillum, Microbacterium and Stenotrophomonas. Multivariate analysis showed that the bacterial endophytic community and diversity of rice seeds are mainly influenced by their host's genotype, physiological adaptation to salt stress and parental lineage.

• Transactions of the Korean Society of Pressure Vessels and Piping
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• v.20 no.1
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• pp.25-31
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• 2024

The core shroud of rector vessel internals (RVI) of OPR1000 and ARP1400 is made of Type 304 stainless steel (SS) by bending and welding process that may induce high deformation and residual stress in manufacturing. This work aims to evaluate the susceptibility of stress corrosion crack (SCC) initiation of bent parts of RVI in high temperature primary water environment. For SCC initiation test, tensile specimens were fabricated from the 90 degree bent plate of Type 304 SS (DT specimen), that is an archived part of a Korean APR1400. After the SCC initiation test, the specimen surface was thoroughly examined by optical and scanning electron microscopy, and compared to the specimen fabricated from the as-received plate of Type 304 SS (AR specimen). The surface observation revealed that SCC initiated on the AR specimen surface in typical intergranular (IG) mode, while SCC on the DT specimen occurred in transgrannular mode as well as IG mode. It was also found that the size and number of SCC on the DT specimen were larger than that on the AR specimen. This was attributable to a strain-hardening during the bending process. To compare the susceptibility of SCC initiation, total crack density (TCD) was calculated from the total crack length divided by the measured area of AR and DT specimens. TCD of DT specimen was 4.6 times higher than AR specimen in average, indicating that higher possibility of degradation of bent parts of RVI for a long-term operation.