• Korean Journal of Veterinary Research
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• v.62 no.2
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• pp.11.1-11.4
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• 2022

A captive female capybara (Hydrochoerus hydrochaeris) of unknown age discharged a bloody mass from the vaginal region. A histopathology examination revealed the mass to be a reproductive leiomyosarcoma, and an ovariohysterectomy was performed. The histopathology examination confirmed that the excised tissue was a uterine leiomyosarcoma. The purpose of this report is to describe clinical history and histopathological diagnosis of leiomyosarcoma in capybaras. This report is novel because it describes the first diagnosis of uterine leiomyosarcoma in a capybara. Since clinical data about capybaras are rare, this case report will help to diagnosis and treat reproductive diseases of this species.

• Clinical and Experimental Pediatrics
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• v.51 no.1
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• pp.98-101
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• 2008

Leiomyosarcoma is an uncommon soft tissue sarcoma of mesenchymal cell origin, which shows smooth muscle differentiation. Leiomyosarcoma is seldom found in the pediatric population, and accounts for fewer than 2% of all soft tissue sarcomas. Leiomyosarcoma of the chest wall is extremely rare in children. We report here a case of an 8-year-old boy with a primary leiomyosarcoma that was incidentally found as a rib mass. The patient underwent a complete resection for a suspected osteochondroma diagnosed by a three-dimensional chest computed tomography examination. Pathological findings of the mass revealed intersecting fascicles of spindle cells showing cigar-shaped nuclei, inconspicuous nuclear pleomorphism and occasional mitotic figures in the background of a suspected osteochondroma of the rib. This report documents the first description of a leiomyosarcoma possibly arising in an osteochondroma of the rib in a child.

• Journal of Chest Surgery
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• v.27 no.3
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• pp.251-254
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• 1994

Esophageal leiomyosarcoma is a rare lesion. [0.5 % of all esophageal malignancy] The patient was 74 year old female and complained postprandial vomiting of 4 years, duration & hematemasis of 2 months` duration. On gastrofiberscopy, huge exophytic mass nearly occluding esophageal lumen located 30∼38 cm from upper incisor was found. Endoscopic biopsy was squamous cell carcinoma. Transthoracic esophagectomy and esophagogastrotomy was carried out. Result of biopsy was esophageal leiomyosarcoma.

• Imaging Science in Dentistry
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• v.36 no.4
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• pp.227-231
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• 2006

Leiomyosarcoma of the oral cavity is a very rare tumor that is associated with aggressive clinical behavior and low survival. In this paper, we report a case of leiomyosarcoma presenting with a gingival exophytic mass that rapidly grew, causing facial asymmetry within 16 days, in a 9-year-old boy. After an excisional biopsy, microscopy revealed a spindle cell neoplasm that, on immunohistochemistry analysis, demonstrated reactivity for SMA. This established the diagnosis of leiomyosarcoma; subsequently, a marginal mandibulectomy and supraomohyoid neck dissection were performed.

• Journal of Chest Surgery
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• v.47 no.1
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• pp.35-38
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• 2014

Leiomyosarcoma may occur anywhere in the body but rarely occurs in the heart or great vessels. Leiomyosarcoma may be managed by surgical resection with or without chemotherapy or radiotherapy. Owing to the high rate of metastasis and poor prognosis, a definitive treatment modality for leiomyosarcoma has not yet been suggested. This case study reports the surgical management of the recurrent leiomyosarcoma of the heart and the great vessels in a 63-year-old woman.

• Tuberculosis and Respiratory Diseases
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• v.42 no.4
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• pp.605-609
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• 1995

Primary leiomyosarcoma of the lung is very uncommon, and fewer than 50 cases now have been reported. Primary leiomyosarcoma of the lung resembles bronchogenic carcinoma in its clinical presentation and radiologic appearance. However, the former has some differences; younger onset than bronchogenic carcinoma, polypoid endobronchial growth, few positive cytologic examination of sputum and unusual lymph node metastasis. We experienced a case of primary leiomyosarcoma of the lung.

• Journal of Chest Surgery
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• v.32 no.12
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• pp.1144-1147
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• 1999

Primary endobronchial leiomyosarcoma is a very uncommon tumor and its diagnosis by spontaneous expectoration of tumor fragment has never been reported in the literature. We report a patient with primary endobronchial leiomyosarcoma that was diagnosed by spontaneous expectoration of partial tumor tissue. The expectorated tissue was found to be pathologically consistent with leiomyosarcoma. Right lower lobectomy and all lymph node dissections were performed during the operation. Pathologic examination showed that the tumor was histologically identical to the patient's previous expectorated tissue and was confined to the bronchus and did not invade the adjacent pulmonary parenchyma and lymph nodes.

• Korean Journal of Head & Neck Oncology
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• v.21 no.1
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• pp.45-47
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• 2005

Leiomyosarcoma of the larynx is very rare, and rarely been described in reference to the head and neck region. This tumor occurs mainly in the uterus, the gastrointestinal track, and the retroperitoneum. There have been 24 previously reported cases of this tumor involving the larynx in the literature. Histologic diagnosis remains extremely difficult. A case of leiomyosarcoma of the larynx, treated by total laryngectomy, is reported. We discuss the clinical presentation, diagnosis, and treatment of leiomyosarcoma with a review of the literature.

• Journal of Korean Academy of Oral and Maxillofacial Radiology
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• v.29 no.2
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• pp.549-559
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• 1999

Leiomyosarcoma is extremely rare in the oral cavity and especially in the mandible. At first. the case of this report was diagnosed as odontogenic fibroma but after approximately 3.5 years. it was diagnosed as leiomyosarcoma. Conventional radiograph of the first time showed an ill-defined radiolucent lesion in the mandible. After local recurrence. CT images showed a large irregular soft tissue mass with some necrotic areas. These findings were not specific for leiomyosarcoma, but they suggested that this lesion was a recurrent soft tissue sarcoma. Histopathological examinations using H & E staining, immunohistochemical staining and Masson's trichrome staining confirmed this case as leiomyosarcoma. Deciding its malignancy or benignancy, defining the tumor extent and its relationship to the surrounding anatomic structures, and evaluating the distant metastasis are more important roles of radiographic examination than finding out the name of disease.

• Journal of Chest Surgery
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• v.26 no.8
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• pp.654-660
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• 1993

The incidence of pulmonary leiomyosarcoma is very rare as a primary lung tumor. Usually, pulmonary leiomyosarcoma arise from the smooth muscle present in the bronchi or blood vessles. We had experienced two cases of primary pulmonary leiomyosarcoma. The first case was 28-year old male patient who had been in good health until admission, when he experienced an episode of dyspnea and sudden hemoptysis. The chest X-ray film revealed a large round tumor mass in left lower lobe measuring 6.5x9.5x5.3cm in dimension. On physical examination,the patient was friction rub and rales on the left lower chest and postoperative course was smooth and non-eventful. Emergency left lower lobectomy was performed due to repeated hemoptysis. Chemotheraphy was done postoperatively as an adjuvant therapy.The second case was 52-year-old man who had been well prior to admission, when recently he noticed a abrupt growing tendency of old pulmonary coin lesion in right lower lobe on routine physical examination. Since 1968, small round mass was gradually enlarged very slowly, during recent one year interval, the tumor mass was enlarged abruptly as twice in size on chest X-ray. Bronchoscopic examination revealed no specipic findings. Right lower lobectomy was performed and pathologic examination was answered as primary leiomyosarcoma without lymph node metastasis. Postoperative course was smooth, except local wound infection.