• 한국인터넷방송통신학회논문지
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• 제24권4호
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• pp.49-55
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• 2024

코드 스멜은 Kent Beck에 의해 사용된 개념으로, 잠재적인 품질 문제를 나타내며 리팩토링의 필요성을 제시한다. 본 논문은 LEA 코드베이스에서 코드 스멜을 평가하며, 분류와 관련된 메트릭에 중점을 둔다. 연구에서는 LEA_core.c와 LEA.cpp를 분석하여 코드 품질과 복잡성의 차이를 강조한다. 또한 연구에서는 LOC, NOM, NOA, CYCLO, MAXNESTING, FANOUT와 같은 메트릭을 사용하여 크기, 복잡성, 결합도, 캡슐화, 상속, 응집도를 평가한다. 연구 결과에서는 LEA_core.c가 LEA.cpp에 비해 더 복잡하고 유지보수가 어려운 것으로 나타났다. 우리는 향후 연구에서 실시간 코드 스멜 탐지 및 리팩토링 제안을 위한 자동화 도구를 개발할 것이다.

• Molecules and Cells
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• 제25권3호
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• pp.428-437
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• 2008

To identify transcriptional markers for beef traits related to meat tenderness and moisture, we measured the transcriptome of the Longissimus dorsi skeletal muscle in 10 Korean native cattle (KNC). We analyzed the correlation between the beef transcriptome and measurements of four different beef traits, shear force (SF), water holding capacity (WHC), cooking loss (CL), and loin eye area (LEA). We obtained non-overlapping and unique panels of genes showing strong correlations (${\mid}r{\mid}$ > 0.8) with SF, WHC, CL, and LEA, respectively. Functional studies of these genes indicated that SF was mainly related to energy metabolism, and LEA to rRNA processing. Interestingly, our data suggested that WHC is influenced by protein metabolism. Overall, the skeletal muscle transcriptome pointed to the importance of energy and protein metabolism in determining meat quality after the aging process. The panels of transcripts for beef traits may be useful for predicting meat tenderness and moisture.

• Animal Bioscience
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• 제35권5호
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• pp.648-658
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• 2022

Objective: The identification of nonlinear mixed models that describe the growth trajectory of New Zealand rabbits was performed based on weight records and carcass measures obtained using ultrasonography. Methods: Phenotypic records of body weight (BW) and loin eye area (LEA) were collected from 66 animals raised in a didactic-productive module of cuniculture located in the southern Piaui state, Brazil. The following nonlinear models were tested considering fixed parameters: Brody, Gompertz, Logistic, Richards, Meloun 1, modified Michaelis-Menten, Santana, and von Bertalanffy. The coefficient of determination (R²), mean squared error, percentage of convergence of each model (%C), mean absolute deviation of residuals, Akaike information criterion (AIC), and Bayesian information criterion (BIC) were used to determine the best model. The model that best described the growth trajectory for each trait was also used under the context of mixed models, considering two parameters that admit biological interpretation (A and k) with random effects. Results: The von Bertalanffy model was the best fitting model for BW according to the highest value of R² (0.98) and lowest values of AIC (6,675.30) and BIC (6,691.90). For LEA, the Logistic model was the most appropriate due to the results of R² (0.52), AIC (783.90), and BIC (798.40) obtained using this model. The absolute growth rates estimated using the von Bertalanffy and Logistic models for BW and LEA were 21.51g/d and 3.16 cm², respectively. The relative growth rates at the inflection point were 0.028 for BW (von Bertalanffy) and 0.014 for LEA (Logistic). Conclusion: The von Bertalanffy and Logistic models with random effect at the asymptotic weight are recommended for analysis of ponderal and carcass growth trajectories in New Zealand rabbits. The inclusion of random effects in the asymptotic weight and maturity rate improves the quality of fit in comparison to fixed models.

• Asian-Australasian Journal of Animal Sciences
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• 제32권4호
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• pp.585-591
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• 2019

Objective: This study investigated carcass characteristics and meat quality of purebred Pakchong 5, crossbred pigs sired by Pakchong 5, and crossbred pigs sired by Duroc. Methods: Forty-eight pigs (average body weight of 22.25 kg) were composed of three groups as purebred Pakchong 5 (PP), Large $White{\times}Landrace$ pigs sired by Pakchong 5 (LWLRP), and Large $White{\times}Landrace$ pigs sired by Duroc (LWLRD). Each group consisted of eight gilts and eight barrows. At 109-day-raising period, pigs were slaughtered, and carcass characteristics were evaluated. Longissimus thoracis (LT) muscles from left side of carcasses were evaluated for meat quality and chemical composition. Data were analyzed using general linear model procedure, where group, sex, and their interaction were included in the model. Results: The PP had greater carcass, total lean, and ham percentages than crossbred pigs (p<0.05). LWLRP had thicker backfat and more carcass fat percentage than LWLRD (p<0.05). There were no differences (p>0.05) on cutting percentages from tender loin, loin, boston butt, and picnic shoulder among groups. The PP and LWLRP had larger loin eye area (LEA) than LWLRD (p<0.05). Gilts had more loin percentage and lower $L^*$ value than barrows (p<0.05). No meat color parameters ($L^*$, $a^*$, and $b^*$) were affected by groups (p>0.05). PP and LWLRP had larger muscle fiber diameters than LWLRD (p<0.05). However, water holding capacity, Warner-Bratzler shear force values, and chemical composition of LT were not affected by group or sex (p>0.05). Conclusion: Pakchong 5 purebred has good carcass and lean percentages. Compared to Duroc crossbred pigs, Pakchong 5 crossbreds have similar carcass and lean percentages, larger LEA, and slightly more carcass fat, with comparable meat quality and chemical composition. Pakchong 5 boars are more affordable for very small- to medium-scale pig producers.

• Asian-Australasian Journal of Animal Sciences
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• 제14권1호
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• pp.123-135
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• 2001

Application of growth promoters by means of implantation or supplementation to the diets has been routine in the beef cattle industry of many countries for the better performance in growth and improvement of feed efficiency. Anabolic implants (zeranol, trenbolone acetate, and estradiol with testosterone or progesterone) have generated various positive effects. Zeranol implantation, in general, improved average daily gain (ADG), feed conversion (FC), dressing percentage (DP) and yield grade (YG) of cattle, and increased dry matter intake (DMI). Trenbolone acetate with or without estradiol also increased mean values of ADG and loin eye area (LEA) but reduced DMI and improved FC of cattle. Estradiol with testosterone or progesterone increased ADG and DMI. Anabolic implants, however, had minimal or negative effects on marbling or quality grade. The magnitude of the response to these anabolic implants in performance of beef cattle has varied depending on the type of implants, amount and duration of exposure, age of animals and combination of implants. Administration of bovine somatotropin improved ADG and FC, and decreased fat deposition. Ionophores improved FC in cattle from reduced DMI without great response to ADG. Supplementation of monensin and lasalocid reduced molar proportion of propionate. Monensin and lysocellin increased apparent absorption and retention of some minerals in cattle. Despite the improved cattle performance in growth and FC, results in beef quality from the application of the growth promoters appeared to vary or in conflict under a variety of environmental conditions.

• 약학회지
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• 제51권3호
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• pp.174-178
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• 2007

A reverse-phase high performance liquid chromatography method with electrospray ionization and detection by mass spectrometry is described for the simultaneous determination of doxifluridine and its active metabolite 5-flu-orouracil (5-FU) in monkey serum. The method has greater sensitivity and simpler process than previous published methods with good accuracy and precision. A proper liquid/liquid extraction was used to extract simultaneously doxifluridine and 5-FU which has considerable difference in the polarity. Extracts were analyzed using LC/MS/MS providing a short analysis time within 5 min. The lower limit of quantification was validated at 10.0 ng/ml of serum for both doxifluridine and 5-FU. Accuracy and precision of quality control (QC) samples for both analytes met FDA Guidance criteria of ±15% for average QC accuracy with coefficients of variation less than 15%. The method will be applicable for preclinical studies and bioequivalence studies.

• Asian-Australasian Journal of Animal Sciences
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• 제20권5호
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• pp.622-626
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• 2007

Using multi-trait animal model BLUP, selection was conducted over seven generations for growth rate (DG), real-time ultrasound loin-eye muscle area (LEA), backfat thickness (BF), and intramuscular fat content (IMF) to develop a new line of purebred Duroc pigs with enhanced meat production and meat quality. This study was intended to investigate the relationship between restriction fragment length polymorphism (RFLP) of a heart fatty acid-binding protein (H-FABP) gene and intramuscular fat content (IMF) of this Duroc purebred population. The present experiment examined the RFLP of 499 slaughtered pigs. The DNA was separated from the blood or ear tissue of the pigs, which were slaughtered at 105 kg of body weight. Intramuscular fat content of the longissimus muscle was measured using chemical analysis. A significant difference was detected in the breeding value of IMF among the H-FABP PCR RFLP genotypes. The AA genotype has a significantly larger positive effect on the IMF breeding value than do the Aa and aa genotypes for the MspI RFLP. In addition, the DD genotype has a significantly greater positive effect on IMF breeding value than the Dd and dd genotypes for the HaeIII RFLP. For the HinfI RFLP, the hh genotype has a significantly larger positive effect on IMF breeding value than the HH genotype. Multiple regression analysis was performed using the IMF breeding values as the dependent variable and the three H-FABP genotypes as independent variables. Results revealed that the contribution of the genotypes to variation in IMF breeding values was approximately 40%. These results demonstrated that H-FABP RFLPs affect IMF in this Duroc population.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2023년도 학술발표회
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• pp.183-183
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• 2023

Smart water cities (SWC) are urban municipalities that utilizes modern innovations in managing and preserving the urban water cycle in the city; with the purpose of securing sustainability and improving the quality of life of the urban population. Understanding the different urban water characteristics and management strategies of cities situate a baseline in the development of evaluation scheme in determining whether the city is smart and sustainable. This research herein aims to develop measurements and evaluation for SWC Key Performance Indicators (KPIs), and set up a unified global standard and certification scheme. The assessment for SWC is performed in technical, as well as governance and prospective aspects. KPI measurements under Technical Pillar assess the cities' use of technologies in providing sufficient water supply, monitoring water quality, strengthening disaster resilience, minimizing hazard vulnerability, and maintaining and protecting the urban water ecosystem. Governance and Prospective Pillar on the other hand, evaluates the social, economic and administrative systems set in place to manage the water resources, delivering water services to different levels of society. The performance assessment is composed of a variety of procedures performed in a quantitative and qualitative manner, such as computations through established equations, interviews with authorities in charge, field survey inspections, etc. The developed SWC KPI measurements are used to evaluate the urban water management practices for Busan Eco Delta city, a Semulmeori waterfront area in Gangseo district, Busan. The evaluation and scoring process was presented and established, serving as the basis for the application of the smart water city certification all over the world. The established guideline will be used to analyze future cities, providing integrated and comprehensive information on the status of their urban water cycle, gathering new techniques and proposing solutions for smarter measures.

• 한국잠사곤충학회지
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• 제36권2호
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• pp.102-109
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• 1994

밀식뽕밭의 성력조성을 위한 접목원묘 직식조성구와 접목묘 식재조성구와 비교하여 식재밀도별(1,666~4,166주/10a) 생산성과 뽕잎의 사료가치를 검정한 결과는 다음과 같다. 1. 색재당년에는 접목묘가 접목원묘에 비하여 생장이 빨라서 주당 주조장이 길었으나, 적심에 의하여 기조장이 증대되지는 않았다. 식재 2년 및 3년차의 춘기 주당 신초장 및 하기의 주당 기조장은 주당 기조수구 많았던 저밀도의 경우가 더 길었으나 10a당 기조장은 밀도에 따라 차이를 나타내어 고밀도일수록 길었다. 2. 불발아 및 고손장비율은 적심여부나 식재밀도에 따른 차이를 인정할 수 없었다. 2. 주당 수량은 접목묘보다 많았으나 그 차이는 식재당년 가을 및 2년차 봄에 크고 그 이후 적어졌다. 식재밀도별 3년 평균주당수량은 1,666주구에 비하여 2,083주구가 다소 적었으나 그 이상 고밀도인 2,777~4,166주구에서는 23~39% 감소하여 큰 차이를 나타내었다. 그러나 10a당 수량은 식재당년부터 밀식일수록 많았으나 해를 경과하면서 그 차이는 적어졌다. 3년 평균으로 보면 2,083~4,166구는 관행 1,666주구에 비하여 20~63% 증수되었으나 2,083주이상에서는 밀도증가인만큼 중수정도가 크지 않았다. 적심은 기조장 및 수량증대에 영향하지 않았다. 4. 식재밀도와 수량구조요인과의 상관관계는 10a당 기조장과 수량과의 사이에 높은 정의 상관이 인정되었으나 식재 2년차이후에는 식재밀도와 주당 수량과 높은 부의 상관을 나타내어 밀식에 따른 단위수량의 증대효과가 감퇴되었다. 5. 1,666, 2,083 및 2,777주 밀도의 1역식 식재양식은 같은 밀도의 2열식에 비하여 생산성이 높았다. 6. 식재밀도별 뽕잎의 사료가치를 누에사육시험에 의해 조사한 결과는 1,666~3,333주 밀도사이에서 상견비율, 수견량, 견중 및 견층중의 차이가 없었다.

• 한국축산식품학회지
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• 제30권6호
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• pp.905-909
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• 2010

Two sets of data on carcass traits and beef cut parameters were used to investigate the relationships between carcass and beef cut measurements, which can be used to make predictions of retail cut percentages. One set had a total of 1,141 measurements of Hanwoo cattle of three different sex origins, which were slaughtered in an abattoir located at the National Institute of Animal Science, RDA, Korea from 1996 to 2008. To develop prediction models for retail cut percentage with higher accuracies than the current model, another set consisting of a total of 13,389 records of carcass and beef cut traits were collected from 30 abattoirs and butcheries in Korea from 2008 to 2009. Bulls yielded heavier and leaner carcasses than steers. High correlation coefficients were estimated between amount of body fat and percent retail cut (-0.82) as well as between back fat thickness (BF) and percent retail cut (-0.62). The amount of retail cut, however, was highly correlated with body weight before slaughter (BW, 0.95) or with cold carcass weight (CWT, 0.94). Relationships between percent retail cut and measurable beef yield traits, BF, loin eye area (LEA) or CWT varied by sex class, which must be considered for development of a prediction model with high accuracy. Models of data for all breeds and sexes fit the effects of breed, sex, and interaction of abattoir by butchers, whereas models of data for each breed and sex fit the effect of interaction of abattoir by butcher only. Due to possible future changes in back fat control, we performed a log transformation of BF. Our new models fit better than the currently used model.