• IMMUNE NETWORK
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• v.21 no.1
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• pp.4.1-4.18
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• 2021

The global outbreak of coronavirus disease 2019 (COVID-19) is still threatening human health, economy, and social life worldwide. As a counteraction for this devastating disease, a number of vaccines are being developed with unprecedented speed combined with new technologies. As COVID-19 vaccines are being developed in the absence of a licensed human coronavirus vaccine, there remain further questions regarding the long-term efficacy and safety of the vaccines, as well as immunological mechanisms in depth. This review article discusses the current status of COVID-19 vaccine development, mainly focusing on antigen design, clinical trials in later stages, and immunological considerations for further study.

• Journal of Society of Preventive Korean Medicine
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• v.23 no.2
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• pp.11-23
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• 2019

Objectives : The purpose of this study was to explore factors related quality of life among cancer survivor in order to identify strategies for cancer survivors to go back to normal life and carry on stable and high quality life. Methods : This study used the $1^{st}$ to $6^{th}$ data of Korean Longitudinal Study of Aging(KLoSA). The sample of this study consisted of 118 cancer survivors, all of whom were diagnosed with cancer for more than 10 years later in 2016. Results : Regression analysis of major factors related to the quality of life of elderly cancer survivors showed that the results of 2006 and 2016 were different. In 2006, factors related to cancer were highly correlated with quality of life, but in 2016, it was associated with pain and depression. Conclusions : The results of this study confirm that the factors related to quality of life in cancer survivors change with survival period. Therefore, this study suggests comprehensive care strategies based on the stage of survivorship.

• Journal of Korean Critical Care Nursing
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• v.12 no.1
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• pp.22-35
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• 2019

Purpose : This study was to determine the levels of environmental stressor, posttraumatic stress disorder, and quality of life in intensive care units (ICU) survivors after intensive care, and to explore the factors affecting posttraumatic stress disorder and quality of life. Methods: With a longitudinal survey design, data were collected from 116 patients who were discharged from the ICU of a university hospital. The environmental stressor, posttraumatic stress disorder, and quality of life were measured immediately following and 1 month after the ICU discharge. Results: Of all the subjects, 16.4% experienced posttraumatic stress disorder after discharge. Multiple regression analysis revealed that ICU environmental stressors, experience of ICU readmission, using psychotropic drugs and narcotic analgesics, and ICU admission after surgery or cardiac intervention accounted for 22.2% of posttraumatic stress disorder. Posttraumatic stress disorder and sedation status when entering ICU accounted for 28.3% of the quality of life 1 month after ICU discharge. Conclusion: Nursing interventions focused on ICU environmental stressors would not only reduce environmental stress but also contribute to the reduction of posttraumatic stress disorder and later improvement of quality of life.

• Korea journal of population studies
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• v.26 no.2
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• pp.63-90
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• 2003

This study aims to discover patterns of Korean women's life course in terms of their life time sequence of family roles and economic activity. Primary factors for the change and diversity of family-work role sequence are also examined. Data used in this study is the Fourth Survey of Korean Women's Economic Activity which was conducted by Korean Institute of Women Development (KIWD) in 2002. According to the main results, five distinctive patterns of life course are to be disentangled for ever married women: First, doing simultaneously family and work roles with no maternal leave (13.7%); second, reentry into labor market after maternal leave (M type, 18.6%); third, no reentry into labor market after maternal leave (latent M type, 26.9%); fourth, first job entry after child rearing (23.5%); and finally, no work experience (17.3%). The relative composition of the respective life course has changed over marriage cohorts. M type including latent M type became a dominant life pattern among married women since marriage cohorts of 1980 and later. The share of married women who begin to work first after maternal role or have no work experience has declined with recent marriage cohorts. It is also noted that the share of women with simultaneous family and work roles has increased among marital cohorts of 1990 and later. Marriage cohort differences being controlled, life patterns significantly differ by women's educational level, existence of role model of working mother at growth, women's own and husbands' gender role attitude, and family economy. Finally, some policy concerns for gender role division of family and work are raised.

• Korean Journal of Human Ecology
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• v.7 no.3
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• pp.83-106
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• 2004

As the lifespan has been expanded, the marital relationship later in life is getting more important. This study is to find out what the demand for the education of marital couples to improve this relationship. The results can be used as basic data to develop educational programs for elder couples. The results of this study are as follows. 1. Couple role according to socio-demographic variables can be divided into traditional and modern roles. And these variables are shown to be significant in couple role. 2. Need for the education of married couples according to socio-demographic variables. In case of spouses having shorter marriage period, religion, and a nuclear family, and doing social activities, the necessity of education is recognized highly. Those who have a spouse with good health and social activities have experienced a chance to attend the educational program. It is thought that health and social activities have much to do with active living attitude. In case of old age, it can be thought that they don't feel the necessity because they have lived a decent life for a long time. It is just that it comes from the fixed ideas of elder couples who had to spend only a short time with their spouses. That is what elder couples have to overcome. They tend to think that the relationship between the family is more important than that of spouses, and they put family relationship before the quality of their own lives. 3. Influence of the need for the education of married couples according to their role. As their role are becoming modern and their mutual trust, affinity, and cohesion are getting more important, the education of married couples and the experiences of communication and participation in the educational program are thought to be more necessary.

• Journal of Korean Academy of Nursing
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• v.37 no.3
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• pp.334-342
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• 2007

Purpose: Ego-integrity in older adults is the central concept related to quality of life in later life. Therefore, for effective interventions to enhance the quality of later life, a scale to measure ego-integrity in older adults is necessary. This study was carried out to develop a scale to measure ego-integrity in older adults. Methods: This study utilized cronbach's alpha in analyzing the reliability of the collected data and expert group, and factor analysis and item analysis to analyze validity. Results: Seventeen items were selected from a total of 21 items. Cronbach's alpha coefficient for internal consistency was.88 for the 17 items of ego-integrity in the older adults scale. Three factors evolved by factor analysis, which explained 50.71% of the total variance. Conclusions: The scale for measuring ego-integrity in Korean older adults in this study was evaluated as a tool with a high degree of reliability and validity.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.18 no.4
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• pp.217-223
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• 2015

The obesity epidemic is a worldwide problem. Factors predisposing to obesity include genetics, race, socioeconomic conditions, birth by cesarean section, and perinatal antibiotic use. High protein (HP) content in infant formulas has been identified as a potential culprit predisposing to rapid weight gain in the first few months of life and leading to later obesity. In a large multicountry study the effects of lower protein (LP) formula (1.77 and 2.2 g protein/100 kcal, before and after the 5th month, respectively) were compared to those of higher protein (2.9 and 4.4 g protein/100 kcal, respectively). Results indicated that at 24 months, the weight-for-length z score of infants in the LP formula group was 0.20 (0.06, 0.34) lower than that of the HP group and was similar to that of the breastfed reference group. The authors concluded that a HP content of infant formula is associated with higher weight in the first 2 years of life but has no effect on length. LP intake in infancy might diminish the later risk of overweight and obesity. At 6 years of age HP children had a significantly higher body mass index (by 0.51; 95% confidence interval [CI], 0.13-0.90; p=0.009) and a 2.43 (95% CI, 1.12-5.27; p=0.024) fold greater risk of becoming obese than those who received the LP. In conclusion, several factors may influence development of metabolic syndrome and obesity. Breastfeeding should always be encouraged. An overall reduction of protein intake in formula non breastfed infants seems to be an additional way to prevent obesity.

• Journal of Families and Better Life
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• v.22 no.6 s.72
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• pp.121-131
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• 2004

The purpose of this study was 1) to analyze the attitudes of people in their 50s about housing problems, and, 2) to study their intention to move into senior congregate housing. The survey was conducted from October to November, 2003 in the Seoul Metropolitan area.'rho data L4·Pre collected from m people using a questionnaire. The results were as follows: First, respondents listed 'friends' as the most important element of their later life. Next, in general, they preferred to live in mainstream family housing. Respondents thought 'family and government' had a responsibility to solve senior citizens 'housing problem. Second, a majority of the participants showed an intention to eventually move into a senior congregate housing. However, the group who did not Intend to live in senior congregate housing had a higher income and greater property assets. The appropriate time for the move to senior congregate housing was keyed to a desire to avoid loneliness. On the other hand, a high degree of satisfaction with current housing was the primary reason given for not wanting to move to senior congregate housing. In conclusion, senior congregate housing should be developed as a model for the middle class and might be successful when combined with a high quality social and health program.

• 한국노년학
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• v.37 no.2
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• pp.399-414
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• 2017

Although previous studies have found that social participation activities are related to older people's life satisfaction and health status, the rate of social participation activities among older people is still low. The current study examined the relationship between age identity and social participation activities among older people and the extent to which this relationship differs by gender. Secondary data from the Survey of Living Conditions of Korean Older Persons were used to test the research hypothesis. Hierarchical multiple regression models were tested using a nationally representative sample of 10,451 community-dwelling older persons aged 65 and above. Older people who have older age identity were less likely to involve in social participation activities than those who have younger age identity. However, this relationship was only significant for older women. The findings suggest the need for attention to age identity and gender differences when promoting social participation activities.

• Journal of the Daesoon Academy of Sciences
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• v.31
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• pp.165-197
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• 2018

The purpose of this article is to investigate communal action in the Ox Seeking Pictures of Daesoon Thought as an expression of future prospects. The Ox Seeking Pictures in Daesoon Thought seeks out renewal of thought, renewal of life, and true living. Here, the Ox Seeking Pictures symbolize a world in which good fortune comes true according to faith in Gucheon Sangje. The correlation between searching for the ox and the supporting teachings of the Reordering Works of Heaven and Earth in Daesoon shows the transformation of Daesoon prospects for achieving the renewal of thought. The correlation between Deep Contemplation Leading to Awakening and Finding and Following Heavenly Teachings shows the transformation of Daesoon reason into a practice implemented in daily life. The correlation between a human being's awareness and the heavenly paradise of the Later World shows transformation into true living based on everyday practice and the practical transformation of one's livelihood. In this investigation, we can say that the Ox Seeking Pictures of Daesoon symbolizes the realization of human dignity and respect for lives. No life should be destroyed or violated by another. Heaven, Earth, and Humanity can be changed and born anew. The visions of the realization of the heavenly paradise of the Later World show that this paradise in the world results from Daesoon principles. This provides a unique insight when compared to the bodhisattva ideal conveyed through the Ox Seeking Pictures of Mahayana Buddhism. Daesoon's Ox Seeking Pictures consist of a three-way interlocking of renewal of thought, implementation in life, and the practical transformation of one's livelihood. The communal spirituality based in Daesoon Truth connects and mediates among people and appears in three aspects. Firstly, it is thought to be a vision of the renewal of thought through the 'Virtuous Concordance of Yin and Yang.' Secondly, it is thought to be the vision of a new life based upon the spirit of Mutual Beneficence. Thirdly, it is thought to be a vision of true living through the realization of human dignity. Because of the appearance of the Ox Seeking Pictures of Daesoon Thought, this narrative picture shows the oxherd as searching for an ox which is the symbol of Daesoon Truth and Dao. Even though he catches the ox, he is still holds the rope to tie the ox to himself. He makes an effort to keep the ox steady. Finally, the oxherd's enlightenment becomes the source of responsibility to help unenlightened people in their struggles. In conclusion, it is necessary to interpret these paintings as the start of the Later World.