• Advances in Traditional Medicine
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• 제7권3호
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• pp.280-285
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• 2007

The methanol extract of leaves of Bruguiera gymnorrhiza (L.) Lam. (Rhizophoraceae) was screened for its antinociceptive and antidiarrhoeal activities. The extract produced significant inhibition in acetic acid-induced writhing in mice at dose of 250 and 500 mg/kg body weight (P < 0.001), comparable to the standard drug diclofenac sodium at the dose of 25 mg/kg of body weight (P < 0.001). When tested for its antidiarrhoeal effects on castor oil-induced diarrhea in mice, it increased mean latent period (P < 0.02) and decreased the frequency of defecation (P < 0.01) significantly at the dose of 500 mg/kg body weight, comparable to the standard drug loperamide at the dose of 50 mg/kg of body weight. The overall results tend to suggest the antinociceptive and antidiarrhoeal activities of the extract.

• The Plant Pathology Journal
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• 제31권2호
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• pp.186-191
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• 2015

Diatoms are a major component of the biological community, serving as the principal primary producers in the food web and sustaining oxygen levels in aquatic environments. Among marine planktonic diatoms, the cosmopolitan Skeletonema costatum is one of the most abundant and widespread species in the world's oceans. Here, we report the basic characteristics of a new diatom-infecting S. costatum virus (ScosV) isolated from Jaran Bay, Korea, in June 2008. ScosV is a polyhedral virus (45-50 nm in diameter) that propagates in the cytoplasm of host cells and causes lysis of S. costatum cultures. The infectivity of ScosV was determined to be strain- rather than species-specific, similar to other algal viruses. The burst size and latent period were roughly estimated at 90-250 infectious units/cell and <48 h, respectively.

• 대한치과보존학회:학술대회논문집
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• 대한치과보존학회 2001년도 춘계학술대회
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• pp.252-252
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• 2001

;The Varicella zoster virus can cause two infectious diseases. The primary infection of this virus leads to Chicken pox and it goes into a latent period until it reveals itself again. When secondarily shown. it is called Herpes Zoster. Herpes Zoster can usually be seen between T-3 and L-2 of immunodepressant patients but in 13%. it is seen in the trigeminal nerve branch. During the predrominal stage. burning sensation, itching. and sharp pain can be experienced unilaterally where the nerve branch is distributed. Patients can also express tooth pain in this stage. After 2-4 days the acute stage begins with its characteristic unilateral macule showing vesicle formation. In this stage fever and fatigue can be experienced. Continuous pain even after the acute stage is called postherpetic neuralgia; deep pain and burning sensation can be expressed by the patient. The sequelae of this disease consists of rare osteomyelitis. necrosis of the jaws. or loss of teeth.teeth.

• Advances in Traditional Medicine
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• 제6권2호
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• pp.157-160
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• 2006

Chandanasav is an Ayurvedic preparation slightly reduced the gastrointestinal motility at the 15 min time interval. It increased the latent period of castor oil induced diarrhoea, slightly decreased number of stool count and lowered the purging index values. Chandanasav significantly reduced the onset and increased the duration of pentobarbital induced sleeping time. No significant analgesic effect was observed from the hot plate study Thus it may have mild constipating and central nervous system depressant activity without any effect on peripheral nervous system.

• Journal of Plant Biology
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• 제37권4호
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• pp.397-402
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• 1994

Possible roles of polyamines in the inhibition of cell elongation in Ranunculus petioles were investigated. Exogenously apoplied polyamines greatly inhibited the auxin-induced petiole growth, while treatment of the tissue with $\alpha$-difluoromethylarginine, the inhibitor of putrescine biosynthesis, further enhanced the growth in the presence of IAA. Inhibitory effect of spermine can also be apparent for fusicoccin-induced elongation, but not for growth induced by a low pH. Spermine also suppressed the ethylene-enhanced growth in the presence of auxin. Using computer-based video digitizer system, the inhibitory effects of spermine on petiole growth were kinetically analyzed. Auxin-induced growth was characterized by an initial and transient growth with a highly elevated rate followed by a steady growth with a slightly reduced rate. Spermine treatment was found to shorten the duration of the initial phase of growth, and to reduce the rates of both the initial and steady growth as well. The latent period for auxin induction was not affected by spermine.

• Journal of Microbiology and Biotechnology
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• 제25권8호
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• pp.1181-1194
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• 2015

Tuberculosis (TB) is an infectious disease transmitted by aerosol droplets and characterized by forming granulomatous lesions. Although the number of people infected in the population is high, the vast majority does not exhibit symptoms of active disease and only 5-10% develop the disease after a latent period that can vary from weeks to years. The bases of the immune response for this resistance are unknown, but it depends on a complex interaction between the environment, the agent, and the host. The analysis of cellular components of M. tuberculosis shows important host-pathogen interactions, metabolic pathways, virulence mechanisms, and mechanisms of adaptation to the environment. However, the M. tuberculosis proteome still remains largely uncharacterized in terms of virulence and pathogenesis. Here, we summarize some of the major proteomic studies performed to scrutinize all the mycobacterial components.

• 한국콘텐츠학회논문지
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• 제18권5호
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• pp.432-445
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• 2018

예비보건의료인들을 포함한 보건 의료인들은 결핵에 노출될 위험이 상대적으로 높기 때문에 이들이 적절한 수준의 지식과 예방행위를 구비하는 것이 중요하다. 예비보건의료인들을 위한 결핵 교육 모형을 구축함에 있어서 문헌고찰을 실시함과 동시에 129명의 예비 보건 의료인과 14인의 의료인들을 대상으로 설문조사와 전화 인터뷰를 실시하였다. 그 결과는 다음과 같다.; 첫째, 문헌 고찰에 근거하여 결핵의 역학, 결핵의 전파 및 병태생리, 검사와 진단, 잠복결핵, 결핵의 치료, 그리고 결핵의 예방 등을 포함한 총 6개의 교육 주제가 파악되었다. 둘째, 예비보건의료인들은 결핵의 역학, 전파 및 병태생리, 잠복결핵 분야에 대해 상대적으로 낮은 지식수준을 보였다. 그러므로 교육과정을 계획할 때, 이러한 지식이 낮은 영역에 더 많은 시간이 할애되어야 할 것이다. 셋째, 의료인들은 결핵역학 교육 시, 결핵의 정의와 유형이 잘 포함되어야 한다고 강조하였으며, 결핵의 전파와 병태생리를 교육할 때에는 병원감염과 감염회로에 관한 내용이 포함되어야 된다고 답변하였다. 이에 덧붙여, 의료인들은 결핵의 진단과 집단검진을 강조하였으며, 잠복결핵 교육 시에는 개인보호장구 착용에 관한 내용이 포함되어야 한다고 반응하였다. 또한, 결핵의 치료에 대한 교육 시, 환자 교육 및 결핵약의 부작용에 대한 내용이 포함되어야 하며, 덧붙여 예비보건의료인들의 자기건강증진 행위 및 체계적인 결핵 교육이 결핵 예방의 중요한 수단이라고 정의하였다. 이러한 결과는 제한된 수의 응답자들과 표집 오차를 포함하고 있기에 결과를 일반화하는데 신중을 기해야 한다. 그러므로 더 큰 연구집단을 이용한 후속 연구를 통해 결핵 교육 모형을 개발하는 것이 필요하다.

• Pediatric Infection and Vaccine
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• 제17권2호
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• pp.137-147
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• 2010

목적 : 본 연구는 소아에서 QuantiFERON-TB Gold(QTB) 검사의 임상적 유용성과 문제점을 평가하기 위해 시행되었다. 방 법: 2007년 1월부터 2009년 6월까지 본원에서 TST와 QTB를 시행 받은 소아청소년 112명의 의무 기록을 후향적으로 조사하였다. 결과 : TST와 QTB의 양성률은 각각 59.8%, 15.2%였고, 두 검사의 일치도는 낮았다($\kappa$=0.209). QTB의 민감도와 특이도는 각각 80.0%, 92.6%였다. QTB 양성율은 임상적 결핵군, 긴밀 접촉군, 일반 접촉군, 비접촉군에서 각각 80%, 14%, 0%, 2% 였으며, 판정보류의 빈도는 9.8%였다. QTB 추적 관찰이 시행된 환자 중, 초기 QTB 양성이었던 6명 중 5명은 치료 종료 후 평균 2.2개월까지 양성이 지속되었다. 결론 : 소아에서 QTB는 민감도가 낮고, 판정보류의 빈도가 높다는 단점이 있으나, 특이도가 높은 장점이 있으므로, TST의 특이도가 낮은 점을 보완하여 결핵의 진단 및 치료 결정에 활용될 수 있을 것으로 생각된다.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제16권7호
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• pp.2169-2190
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• 2022

The COVID-19 pandemic has affected many aspects of human life. The pandemic not only caused millions of fatalities and problems but also changed public sentiment and behavior. Owing to the magnitude of this pandemic, governments worldwide adopted full lockdown measures that attracted much discussion on social media platforms. To investigate the effects of these lockdown measures, this study performed sentiment analysis and latent Dirichlet allocation topic modeling on textual data from Twitter published during the three lockdown waves in Malaysia between 2020 and 2021. Three lockdown measures were identified, the related data for the first two weeks of each lockdown were collected and analysed to understand the public sentiment. The changes between these lockdowns were identified, and the latent topics were highlighted. Most of the public sentiment focused on the first lockdown as reflected in the large number of latent topics generated during this period. The overall sentiment for each lockdown was mostly positive, followed by neutral and then negative. Topic modelling results identified staying at home, quarantine and lockdown as the main aspects of discussion for the first lockdown, whilst importance of health measures and government efforts were the main aspects for the second and third lockdowns. Governments may utilise these findings to understand public sentiment and to formulate precautionary measures that can assure the safety of their citizens and tend to their most pressing problems. These results also highlight the importance of positive messaging during difficult times, establishing digital interventions and formulating new policies to improve the reaction of the public to emergency situations.

• 가족자원경영과 정책
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• 제27권3호
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• pp.67-75
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• 2023

본 연구의 목적은 세대적, 생애주기적으로 구분되는 특성을 보이는 30대의 가사노동 참여 유형을 분석함으로써 가사노동의 속성이 어떻게 변화하고 있는지를 살펴보는 것이다. 이를 위해 2020년 가족실태조사 자료에서 추출한 30대 남녀 2,687명의 가사노동 참여 여부를 유형화 지표로 잠재계층분석을 하였다. 분석결과, 전반적 비참여형(18.05%), 전반적 참여형(59.96%), 청소 집중형(21.99%)의 3개 집단으로 유형화되었다. 가사노동 참여 유형과 관련된 요인으로는 성별, 취업상태, 가족생애주기, 성역할 태도가 유의하였다. 여자는 남자보다 청소집중 참여형보다 전반적 비참여형에 속할 확률이 낮았으며, 전반적 참여형에 속할 확률이 높았다. 가족생애주기에 따라서는 형성기 이전인 경우에 청소 집중 참여형보다 전반적 비참여형에 속할 확률이 높았으며, 형성기, 확대기인 경우에는 청소 집중 참여형보다 전반적 참여형에 속할 확률이 높았다. 본 연구결과는 가사노동의 성불평등성이 젊은 세대인 30대에게도 유효함을 시사하며, 같은 세대 내에서도 가족생애주기에 따라 가사노동 참여 유형이 다르다는 것을 보여준다.