• Title/Summary/Keyword: large-cell

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The Influence of Light Reduction on the Growth of Microcystis aeruginosa and Variation of Environmental and Chemical Parameters in Large-scale Cultivation System

  • Yang, Taehui;Cho, Ja-young;Kang, Ha-jin;Lee, Chang Soo;Kim, Eui-jin
    • Korean Journal of Ecology and Environment
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    • v.53 no.4
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    • pp.336-343
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    • 2020
  • Large-scale cultivation of Microcystis aeruginosa in different light conditions was conducted for verifying the cell growth in a greenhouse system. Environmental and chemical parameters of the large-scale culture medium were measured for analyzing the interaction between M. aeruginosa and its symbiotic bacteria. During cultivation, a difference in cell growth pattern was observed between control (natural light) and light-limited groups (reduction of blue, green, and blue/green light, respectively). Comparing the control group, the light reduced groups showed slow and delayed cell growth through the cultivation period. Also, there is differences in the consuming pattern of total nitrogen and total phosphorus which indicated that the possibility of interaction between M. aeruginosa and symbiotic bacteria.

Multifocal Extranodal Involvement in Diffuse Large B-cell Lymphoma (DLBCL): Bone, Soft tissue, Testis, and Kidney

  • Cho, Jae Sung;Lee, Kyung Ryeol;Kim, Bong Soo;Choi, Guk Myung;Lee, Jeong Sub;Huh, Jung Sik;Jang, Bogun
    • Investigative Magnetic Resonance Imaging
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    • v.26 no.1
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    • pp.48-54
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    • 2022
  • In this report we present a case of disseminated diffuse large B-cell lymphoma (DLBCL) in a 79-year-old man affecting the bone, soft tissue, testis, and both kidneys, which are rarely affected sites. The formation of a large mass in the bone, soft tissue, and testis due to DLBCL is rarely seen nowadays. In this article, we describe the imaging findings and clinical significance of multifocal extranodal involvement in DLBCL, focusing on involvement of bone, soft tissue, and testis.

Dead-end Mode Operation of a Large Scale PEM Fuel Cell Stack (대면적 고분자전해질 연료전지의 데드엔드 운전)

  • Jeong, Jeehoon;Shin, Hyunkhil;Han, In-Su;Seo, Hakyu;Kim, Minsung;Cho, Sungbaek;Hur, Taeuk
    • 한국신재생에너지학회:학술대회논문집
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    • 2010.11a
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    • pp.83.1-83.1
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    • 2010
  • A Dead-end mode operation is one of the best way to maximize the gas usage rate. But, some components of fuel cell stack like gas diffusion layer(GDL) or membrane can be damaged in dead-end mode operation. In this study, a Large Scale Polymer electrolyte membrane fuel cell(PEMFC) for a dead-end operation has been developed. The stack is composed with 4 cells which has over 400cm2 of active area. Hydrogen is used as a fuel, and oxygen is used as a oxidant. The dead-end operation performance was evaluated by a long-term dead-end mode operation. The fuel cell stack is operated over 1,500 hours in dead-end mode operating fuel cell test station. And the performance change of the fuel cell stack was investigated.

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Study on Soft-Switching Transformers Inductor Boost Converter for Fuel Cell Powered Railway Vehicle

  • Jung, No-Geon;Kim, Jae-Moon
    • Journal of Electrical Engineering and Technology
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    • v.13 no.6
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    • pp.2553-2560
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    • 2018
  • In Korea, there are no instances where a hydrogen fuel cell power generation system has been used in a railway vehicle. Only the basic topology has been studied. In the previous study, conventional converters using a single switch were applied to the fuel cell power generation system. Therefore, current stress on the switch at converter on-off transitions would be large when controlling a large-capacity railway vehicle. In addition, since the input side ripple is also large, there is a problem with a shortening of the lifetime of both the fuel cell power generation system and the inductor. In this paper, a soft-switching transformer inductor boost converter for fuel cell powered railway vehicles was proposed. A technique to reduce both the switching current stress generated during on-off transitions, and the input ripple current flowing in the inductor were studied. The soft-switching TIB converter uses a transformer-type inductor to configure the entire circuit in an interleaved method, and reduces both input current ripple and the current ripple of the inductor and switch.

Combined Large Cell Neuroendocrine Carcinoma with Component of Adenocarcinoma-A case report- (선암종의 요소를 갖느느 혼압대세포신경내분비암종-1예 보고-)

  • Park Jong Un;Lee Jae Woong;Jo Tae Jun;Kim Kun Il;Lee Weon Yong;Hong Ki Woo;Eom Kwang Seok;Jun Sun-Young
    • Journal of Chest Surgery
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    • v.38 no.8 s.253
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    • pp.579-582
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    • 2005
  • Combined large cell neuroendocrine carcinoma is an uncommon lung cancer that include large cell neuroendocrine carcinoma with components of adenocarcinoma, squamous cell carcinoma, giant cell carcinoma and/or spindle cell carcinoma histologically. We report a case that pathologically diagnosed as combined large cell neuroendocrine carcinoma with component of adenocarcinoma after right pneumonectomy and mediastinal lymph node dissection. A 44-year-old man with intermittent chest pain was referred to our hospital for lung mass on the right mid lung field.

Oxidation-Deficient Silkworm Hemolymph as a Medium Supplement for Insect Cell Culture

  • Kim, Eun-Jeong;Park, Ji-Young;Kim, Sam-Eun;Park, Tai-Hyun
    • Biotechnology and Bioprocess Engineering:BBE
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    • v.3 no.2
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    • pp.87-90
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    • 1998
  • Hemolymph is oxidized and darkens visibly during the collection from silkworm due to the activity of tyrosinase in it. Toxic quinones are produced by the oxidation and consequently inhibit the cell growth. Heat treatment can be used to prevent the oxidation ; however, the oxidation may occur during the collection of hemolymph before it is heat-treated. It makes the hemolymph collection difficult especially on a large-scale preparation. Hemolymphs collected from 257 different strains of silkworms were examined to select the slowly oxidized hemolymphs. Hemolymphs collected from mutant strains such as Lemone, TBO, Cre, Y4, and wEb showed relatively slow color changes. Oxidation rates of the hemolymphs were measured by the absorbance change using a spectrophotometer. The hemolymph of wEb showed the slowest oxidation. The absorbance of this mutant hemolymph reached the saturation value at 20$^{\circ}C$ in 450 min, whereas the total oxidation time of the wild-type (Baekokjam) hemolymph at the same temperature was 120 min. We tested if this mutant hemolymph is useful as a medium supplement for insect cell culture. Cell growth rate and final cell concentration in the medium supplemented with the wEb hemolymph were almost same as those in the medium supplemented with the wild-type hemolymph. Hemolymph is collected on a small scale by clipping the abdominal leg; however, this method is not appropriate fro large scale preparation. Centrifugation after chopping the silkworm hemolymph by a blending mixer is a more appropriate procedure for large scale collection. Slowly oxidized wEb hemolymph resulted in higher cell concentration than the wild-type hemolymph when hemolymph was collected by the large scale preparation method.

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Fine Needle Aspiration Cytology of Anaplastic Large Cell Lymphoma - A case mimicking malignant fibrous histiocytoma - (역형성 대세포 림프종의 세침흡인 세포학적 소견 - 악성 섬유성 조직구중을 닮은 1예 보고 -)

  • Lee, Jung-Won;Oh, Young-Lyun;Ko, Young-Hyeh
    • The Korean Journal of Cytopathology
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    • v.9 no.1
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    • pp.99-104
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    • 1998
  • Anaplastic large cell lymphoma(ALCL) is an uncommon type of non-Hodgkin's lymphoma(NHL) populated with anaplastic, often bizarre cells that express CD30 (Ki-1) antigen. The unusual histologic and cytologic features may cause confusion with other neoplasms, such as poorly differentiated carcinoma, melanoma, Hodgkin's disease, or true histiocytic lymphoma. Although the cytologic features of ALCL have been well described, there are few reports about cytologic findings of the sarcomatold variant of ALCL. We experienced a case of fine needle aspiration(FNA) cytologic findings of ALCL which mimicks malignant fibrous histiocytoma. FNA cytology of chest wall mass in a 62-year-old female with a history of peripheral T-cell lymphoma(Lennert lymphoma) revealed a heterogeneous population of single cells and poorly cohesive cells with large, pleomorphic nuclei and spindle cells gathering around vascular structures within an inflammatory background. Additional features of the neoplastic cells were eccentric, multilobated nuclei with occasional 'wreath-like' configuration; abundant cytoplasm with vacuolization; and prominent nucleoli. The cytologic features suggested sarcoma, especially malignant fibrous histiocytoma. The diagnosis was made retrospectively with an aid of immunocytochemical staining.

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Case of a Diffuse Large B-Cell Lymphoma Patient Treated with Traditional Korean Medicine Treatment (미만성 거대 B세포 림프종 환자의 한의약치료 증례보고)

  • Kim, In Soo;Cheong, Min Sung;Oh, Hyun Seung;Lee, Young Su
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.28 no.2
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    • pp.233-237
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    • 2014
  • This case report that the therapeutic effects of traditional Korean medicine(TKM) treatment on the tumor response in a diffuse large B-cell lymphoma(DLBL) patient. A patient was treated by acupuncture, pharmacopuncture, moxibustion, cupping and herbal medicine once a week at least for 12 months. we evaluated the grade of chief complaints and performed blood tests and sonography, abdominal CT periodically. After 1 month administration with TKM treatment, the symptoms of the patient vanished obviously. the size of inguinal lymphoma decreased gradually through 3 months. then from 3 to 10 months, the size of inguinal lymphoma remained as it is. TKM treatment was maintained continuously. in the abdomino-pelvic CT performed after 12 months, the patient didn't complain any symptom and the size of inguinal lymphoma decreased a little again. This case study supports that TKM treatments may have a efficacy in treating diffuse large B-cell lymphoma(DLBL) patients.

A Case of Nasal Diffuse Large B-Cell Lymphoma in a Cat

  • Kim, Seong-Jun;Kim, Jun-Young;Oh, Dong-Keun;Cho, Jun-Ho;Park, Hee-Myung;Kang, Min-Hee
    • Journal of Veterinary Clinics
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    • v.35 no.4
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    • pp.141-143
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    • 2018
  • A 6-year-old spayed female Turkish Angora cat presented with sneezing, nasal discharge, and decreased appetite lasting for 21 days. Skull radiography revealed slightly increased density of soft tissue in the left nasal cavity. Computed tomography (CT) scan revealed an extensive mass with nasal septum destruction and moderate contrast enhancement in the left nasal cavity. After surgical biopsy, histopathological examination confirmed that the mass was an infiltrative round cell neoplasm, composed of sheets of large neoplastic cells. Immunohistochemical analysis revealed that most of the neoplastic cells were strongly positive for CD79a and weakly positive for PAX5. Additionally, numerous mature lymphocytes were found to be positive for CD3. This is the first reported case of nasal diffuse large B-cell lymphoma (DLBCL) in a Turkish Angora cat in Korea.

Diffuse Bone Marrow Uptake of $^{99m}$Tc-MIBI in A Case of Intravascular Large B-cell Lymphoma (혈관내 B 대세포 림프종 환자에서 발견된 $^{99m}$Tc-MIBI의 미만성 골수 섭취)

  • Moon, Seung-Hwan;Oh, So-Won;Paeng, Jin-Chul;Paik, Jin-Ho;Lee, Dong-Soo
    • Nuclear Medicine and Molecular Imaging
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    • v.43 no.4
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    • pp.352-356
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    • 2009
  • Intravascular large B-cell lymphoma (IVLBCL) is a subtype of diffuse large cell lymphoma, characterized by proliferation of lymphoid cells in the intravascular space of various organs without causing a mass effect. Although $^{18}$F-FDG PET is a powerful imaging tool in lymphoma, the usefulness of $^{18}$F-FDG PET in the assessment of IVLBCL is still controversial. $^{99m}$Tc-MIBI, a tumor imaging radiopharmaceutical with a different mechanism from that of $^{18}$F-FDG, has been reported to be also effective in lymphoma. However, there is nearly no report on the efficacy of $^{99m}$Tc-MIBI in the assessment of IVLBCL. We present one case of IVLBCL that showed $^{99m}$Tc-MIBI accumulation in the involved bone marrow as an incidental finding, which was discrepant from that of $^{18}$F-FDG PET.