• Title/Summary/Keyword: large intestine

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An experimental study of Wahngkigunchungtanghapleechungtang on the effects of gastric ulcer and gastro-intestinal function in rats and mice (황기건중탕합리중탕(黃耆建中湯合理中湯)이 항궤양(抗潰瘍) 및 위장관(胃腸管) 기능(機能)에 미치는 효과(效果)에 대(對)한 실험적(實驗的) 연구(硏究))

  • Sung, Eun-Mi;Baik, Tae-Hyeun
    • The Journal of Internal Korean Medicine
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    • v.18 no.1
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    • pp.242-254
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    • 1997
  • An experimental studies were done to investigate the spontaneous movements to the isolated ileum with the liquid extracts of Wahngkigunchunghapleechungtang. Then the effects of isolated ileum, pylorus-ligated and indomethacin-induced ulcer, gastric juice secretion, and transport abilities of the small and large intestine were studied. The following results have been obtained; 1. Wahngkigunchunghapleechungtang showed to have an inhibitory effects on the smooth muscle contraction of the isolated ileum by acetylcholine chloride and barium chloride. 2. Wahngkigunchunghapleechungtang showed to have an inhibitory effect on the contraction of the gastric fundus-strip by acetylcholine chloride and barium chloride. 3. The preventive effects were not recognized on the pylorus-ligated ulcer, by administration of Wahngkigunchunghapleechungtang. 4. The preventive effects were recognized on the indomethacin-induced ulcer by administration of Wahngkigunchunghapleechungtang. 5. The Inhibitory effects on the secretion gastric juice, free & total acidity, and pepsin output were recognized by administration of Wahngkigunchunghapleechungtang. 6. The transport abilities in the small intestine were not recognized by administration of Wahngkigunchunghapleechungtang. 7. The transport abilities in the large intestine were increased by administration of Wahngkigunchunghapleechungtang. According to the above results, it is considered that the experimental effects of Wahngkigunchunghapleechungtang has correspond to the oriental medical literatures.

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Botulism in a Mute Swan(Cygnus olor) (혹고니(Cygnus olor)의 보툴리눔독소증)

  • Kim, Young Seob;Kim, Bo Suk;Shin, Nam Shik
    • Korean Journal of Veterinary Research
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    • v.48 no.2
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    • pp.161-165
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    • 2008
  • Many neurotoxigenic clostridia are found in soil. Among animals, birds are especially susceptible to botulism, perhaps because they feed on insects, invertebrate carcasses, and decayed feeds contaminated with spores of Clostridium (C.) botulinum. C. botulinum type C is mainly involved in avian botulism. In the summer of 2005, death of a mute swan (cygnus olor) living in the pond of large bird cage was found in Seoul Grand Park Zoo. The birds presented presumptive clinical signs of botulism, such as ruffled hackle feathers, abnormal posture of the head, weakness, and flaccid paralysis. At that time, pond water in the breeding facilities was drained for 7 days, but there were still remained water containing sediment of feed and feces. Therefore, botulism was suspected and an experimentation were made to detect C. botulinum in the dead mute swan. Gross post-mortem findings of a mute swan showed jelly-like hemorrhagic contents in the intestine, sands and vegetations in the stomach. C. botulinum was isolated from the liver, small intestine and large intestine samples. Botulism was also confirmed by mouse inoculation test with the organ samples. With PCR, a gene encoding C. botulinum type C toxin was detected for the several organs of the mute swan died. These results suggested that death of mute swan was caused by C. botulinum type C.

An experimental study of Daegunchungtang on the gastric ulcer and the function of gastrointestinal tract in rats and mice (대건중탕(大建中湯)의 항궤양(抗潰瘍) 및 위장관(胃腸管)에 미치는 효과(效果)에 관(關)한 실험적(實驗的) 연구(硏究))

  • Kim, Hyuk-Kyu;Baik, Tae-Hyeun
    • The Journal of Korean Medicine
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    • v.18 no.1
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    • pp.238-250
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    • 1997
  • This study was done to investigate the clinical effects of Daegunchungtang on the peptic ulcer and the function of gastointestinal tract. The liquid extracts of Daegunchungtang was administerd orally to the rats and mice. Then the effects of isolated ileum, pylorus-ligated and indomethacine-induced ulcer, gastric juice secretion, and transport abilities of the small and large intestine, were studied. The following results have been obtained : 1. Daegunchungtang showed to have an inhibitory effects on the smooth muscle contraction of the isolated ileum by acetylcholine chloride and barium chloride. 2. Daegunchungtang showed to have an inhibitory effect on the contraction of the gastric fundus-strip by acetylcholine chloride and barium chloride. 3. The preventive effects were recognized on the pylorus-ligated ulcer, by administration of Daegunchungtang. 4. The preventive effects were recognized on the indomethacine-induced ulcer, by administration of Daegunchungtang. 5. The Inhibitory effects on the secretion gastric juice, free & total acidity, and pepsin-output were recognized, by administration of Daegunchungtang. 6. The transport abilities in the small intestine were increased, by administration of Daegunchungtang. 7. The transport abilities in the large intestine were not recognized, by administration of Daegunchungtang. According to the above results, it is considered that the experimental effects of Daegunchungtang has correspond to the oriental medical literatures.

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Effect of Chinese Yam on Benzo[a]pyrene Hydroxylase Activities in Rats Fed Dietary Benzo[a]pyrene

  • Kwon, Chong -Suk;Chung, Koo -Min
    • Preventive Nutrition and Food Science
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    • v.4 no.3
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    • pp.193-196
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    • 1999
  • To investigate the effect of yam on the activity of benzo[a]pyrene hydroxylase(BPH), the key enzyme associated with polycyclic aromatic hydrocarbons(PAHs) metabolism, rats were fed a fiber free diet for 7 days, whereupon they were switched to experimental diets for another 7 days. Diets contained benzo[a] pyrene(BP, 400 mg/kg diet) and 25% or 50% yam powder (freezer dried and hot air dried ). Diets containing pectin and cellulose were compared with diets containing yam. BPH activities were assessed in the liver, lung, kidney, stomach, small intestine and large intestine of rats. BP induced BPH activities in various tissues ; 8 fold in liver, 28 in lung and stomach , and 32 in large intestine. The addition of yam significantly lowered BPH activity in liver, lung and stomach and hot air dried yam was nmor eeffectivie than freeze dried yams. These data suggested that yam containing diet may influence carcinogen metabolism in liver and extrahepatic target tissues by altering activities of BPH and may reduce exposure of these tissues to dietary carcinogens.

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Bronchial Carcinoid with Familial Adenomatous Polyposis Coli - 1 Case (가족성 산종성 대장용종증이 동반된 bronchial carcinoid: 1례)

  • 김용환
    • Journal of Chest Surgery
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    • v.25 no.5
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    • pp.544-549
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    • 1992
  • Carcinoid tumors can be ubiquitous, but most will originate in four sites: appendix [38%], small intestine[24%], rectum[13%] or bronchus[11.6%]. And bronchial carcinoids are rare, accounting for only 1% to 6% of all primary lung tumors. Familial adenomatous polyposis cali, the most common form of the polyposis syndromes attributable to a genetic defect, is defined by demonstration of at least 100 adenomatous polyps in the large intestine. We experienced a case of typical bronchial carcinoid with familial adenomatous polyposis cali in 23 year old female patient, which was surgically treated by left lower lobectomy.

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Morphological Review on Mitochondria Damage by Irradiation (방사선에 의한 미토콘드리아 손상의 형태학적 고찰)

  • JI, Tae-Jeong
    • Journal of radiological science and technology
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    • v.43 no.1
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    • pp.29-34
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    • 2020
  • Mitochondria was observed much around the nuclear membrane of liver tissue where the energy metabolism process is active. Testis tissue had a large number of undifferentiated cells, and cristae in Inner membrane of Mitochondria was not observed clearly. Morphological damage occurred first in Inner membrane rather than the outer membrane. The kidney tissue was clearly observed in the form of cristae. Radiation-induced damage occurred at the edges of both ends, and the membrane was observed bursting with the thickness of the outer membrane. Small intestine cells were observed in many mitochondria in the tissues around the villus, where bowel movements were active. Morphological damage occurred with the outer and inner membranes getting tangled. Mitochondria sensitivity to radiation was sensitized in testis and small intestine tissues, and kidney, ovary and liver tissues were found to be resistant.

An Experimental Study on the Effectiveness of Microwave Hyperthermia Combined with Radiation on the Small and Large Intestine in rats (흰쥐의 장조직에 X-선 조사와 마이크로파 온열요법의 효과에 관한 실험적 연구)

  • Ahn, Kyung-Sook;Lee, Kyung-Ja;Rhee, Chung-Sik
    • Radiation Oncology Journal
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    • v.5 no.2
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    • pp.83-95
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    • 1987
  • The synergistic effect of combining radiation therapy and hyperthermia kills significantly more cells than using either modality alone. The reason for enhanced cell killing from the combined treatment is that the two modalities are complementary. For histopathological exmination, 102 rats were divided into 4 groups as hyperthermia, radiation, hyperthermia combined with radiation and normal control groups. The effect of prior irradiation (6-15 Gy of X-ray) on the response of small and large bowel of rats to $40^{\circ}C-44^{\circ}C$ (for 30 minutes) microwave (2450 MHz) hyperthermia was investigated. The musculature of the small and large intestine remained intact and the circumference of the histological sections were not significantly altered by the heated at $43^{\circ}C$ for 30 minutes. Thermal enhancement ratios of normal tissue is 1.0 Thermal enhancement ratio was not increased in combination therapy by evaluation of histopathologic changes in small and large intestine.

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Study on the Respiratory Organ of Spined Loach, Iksookimia longicorpa (Pisces, Cobitidae), in Relation to the Air-breathing System (공기호흡과 관련된 왕종개(미꾸리과어류)의 호흡기관에 관한 연구)

  • Park, Jong-Young
    • Korean Journal of Ichthyology
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    • v.17 no.4
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    • pp.241-247
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    • 2005
  • To observe the respiratory system in relation to the air-breathing organ in Iksookimia longicorpa, micro-anatomical investigation was performed on the epidermis and on intestinal tract fragments. The epidermis was distinguished by two types of skin glands, a small mucous cell and a large club cell. The mucous cell was acid sulfomucins (some sialomucins), but the club cell did not give any histochemical tests for mucosubstances. The presence of a well defined lymphatic system with small lymphocytes was established in the stratum germinativum layer of the epidermis. A large number of blood capillaries run very close to each other just below the basement membrane. The straight intestinal tract is divided into an intestine and rectum, which consisted of a mucosa (epithelial layer), lamina propria-submucosa, muscularis, and serosa. The intestine and rectum have shorter mucosal folds and a thinner wall. The majority of the epithelial mucous cells contain acid sulfomucines. Based on the above results, I. longicorpa adapts to poor dissolved oxygen conditions by using an additional respiratory system using air through the epidermis, not the intestines.

Differences in Electric Potential of Meridian System - Comparing Electric Potentials of Patients with Arthroncus of Knee - (슬안풍 환자의 십이경맥 전위측정 연구)

  • Nam, Bong-Hyun;Choi, Hwan-Soo
    • Korean Journal of Acupuncture
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    • v.21 no.4
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    • pp.21-30
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    • 2004
  • Objectives : Assuming that the characteristic of meridian system has been similar to this of electric potentials in human body and that measurements of electric potential at well(井穴) and sea(合穴) points in branches of the twelve meridians(WSBTM) will be representative of measurements of the twelve meridians, to measure the electric potentials of 13 patients with Arthroncus of Knee(슬안풍<膝眼風>, AK), to find out the characteristic of meridian system in patients with AK. Methods : Electric potentials of well and sea points in the meridians in twenty one patients with the pain in the lion diagnosed as AK were repeatedly measured by physiograph(PowerLab). Measurements of those electric potentials were analyzed by factor analysis. Results : Their electric potentials at the left and right side were factors which are different from each side. In the left side, Factor 1 included Small Intestine, Pericardium, Spleen, Kidney meridian, and Factor 2 included Heart, Tripple Energizer, Bladder, Liver meridian. Factor 3 included Large Intestine, Stomach, Gall bladder meridian, and Factor 4 included Lung meridian. In the right side, Factor 1 included Heart, Pericardium, Tripple Energizer, Spleen, Bladder meridian and Factor 2 included Lung, Liver, Gall bladder meridian. Factor 3 included Small Intestine, Stomach, Kidney meridian and Factor 4 included Large Intestine Meridian. Conclusions : The electric potentials of AK differ from those of normal bodies as well as of bodies with other diseases-shoulder lesions, waist lesions, Lumbago due to Strain and Contusion-. Thus electric potentials of well and sea points might be the representative meridian to show their characteristics.

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