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Guidelines for experimental design and statistical analyses in animal studies submitted for publication in the Asian-Australasian Journal of Animal Sciences

  • Seo, Seongwon;Jeon, Seoyoung;Ha, Jong K.
    • Asian-Australasian Journal of Animal Sciences
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    • v.31 no.9
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    • pp.1381-1386
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    • 2018
  • Animal experiments are essential to the study of animal nutrition. Because of the large variations among individual animals and ethical and economic constraints, experimental designs and statistical analyses are particularly important in animal experiments. To increase the scientific validity of the results and maximize the knowledge gained from animal experiments, each experiment should be appropriately designed, and the observations need to be correctly analyzed and transparently reported. There are many experimental designs and statistical methods. This editorial does not aim to review and present particular experimental designs and statistical methods. Instead, we discuss some essential elements when designing an animal experiment and conducting statistical analyses in animal nutritional studies and provide guidelines for submitting a manuscript to the Asian-Australasian Journal of Animal Sciences for consideration for publication.

무당개구리 (Bombina orientalis) 배아에서 제초제 Molinate에 의한 발생 위해성 평가 및 Biomarker 유전자 발굴

  • Gang Han Seung;Gye Myeong Chan;Kim Mun Gyu
    • Proceedings of the Korea Society of Environmental Biology Conference
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    • 2004.12a
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    • pp.124-126
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    • 2004
  • Molinate is thiocarbamate herbicide used primarily in rice production. Chondrogenesis is a multistep process that is essential for endocondral bone formation. The transcription factor Sox9 has an essential role during the sequential steps of chondrocyte differentiation. Bombina orientalis is one of the most common amphibians in the world and comprises a large proportion of their total number. We examined the embryotoxic and survival effects of molinate at various concentration in B. orientalis embryos. The survival rates of embryos at 312h post fertilization treated with molinate was decreased with concentration dependent manner. Also, developmental malformations appeared by molinate in B. orientalis embryos. the expression levels of Sox9 mRNA was examined by RT-PCR. In our result showed that Sox9 expression was found to be increased in malformed tadpole compared to normal tadpole. These results suggested that molinate was detrimental for survival and development of B. orientalis embryo.

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A Study for analysis of Inverse Kinematics system to Character Animations & Motion Graphics education

  • Cho, Hyung-ik;Shin, Seung-Jung
    • International journal of advanced smart convergence
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    • v.10 no.3
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    • pp.149-156
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    • 2021
  • Today, 3D softwares have become an essential tool in all areas of Video, including Movies, Animations, CFs, Motion Graphics and Games. One of the most commonly used fields is the 3D character video part. However, these 3D character animations and motion graphics softwares are difficult to learn and too much to learn, making it difficult to learn them all in a university education with a limited time of four years. In this paper, many Inverse kinematics tools, which are essential in the 3D character animations and motion graphics field, compare and analyze the strengths and weaknesses of each tool, focusing on Bone, Character Studio, and Character Animation Toolkit, which are most commonly used in work fields. And use Delphi techniques for 3D experts to secure objectivity. Therefore, for universities that require large amounts of teaching in a limited time, I propose an analysis of which of the above three Inverse Kinetics tools is advantageous for students to select and focus on for efficient education.

A Study on Fire and Evacuation in the Public Relations Room of Waste Treatment Facilities (폐기물 처리시설 홍보실내 화재 및 피난에 관한 연구)

  • Lee, Jae-Young;Jeon, Yong-Han
    • Journal of the Korea Safety Management & Science
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    • v.23 no.1
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    • pp.17-22
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    • 2021
  • The public relations room of the waste disposal facility is a space that can be visited by a large number of unevaluated personnel. Therefore, it is essential to design against fire, and research on fire and evacuation is essential. In this study, in order to evaluate the safety of the occupants in the event of fire and evacuation based on the life safety standards of occupants, the increase in risk due to heat, visible distance, and toxic gases on a plane 1.8m from the floor, which is the limit of breathing of the evacuee, over time. It was analyzed by location. As a result, the RSET of the P-01 exit was 93.0 seconds and the ASET was 272.6 seconds, the RSET of the P-02 exit was 45.8 seconds, the ASET was 147.7 seconds, the RSET of the P-03 exit was 106 seconds, and the ASET was 182.9 seconds.

Technical Management Processes for Large National R&D Projects : Focused on Pyro Project (대형 국가 R&D 프로젝트의 기술관리 프로세스 : 파이로 프로젝트를 중심으로)

  • Kim, Jeong-Guk;Ko, Won-Il;Ku, Jeong-Hoe;Nam, Hyo-On
    • Journal of the Korean Society of Systems Engineering
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    • v.13 no.2
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    • pp.34-41
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    • 2017
  • The Pyro project, one of the large national R&D project to construct Korea Advanced Pyroprocessing Facility (KAPF), which has many goals such as development of pyro technology and process equipment, design of equipment and facility, construction, and test operation, is now under research and development. To reduce uncertainty and risk of such complex project, the technical management processes in systems engineering standards and NASA handbook were reviewed, and then the ten common technical management processes were selected for the large national R&D project to meet its goal successfully. And the essential technical management processes were finally suggested for Pyro project in consideration of current situation of the project.

Taming of large diameter triaxial setup

  • Nair, Asha M.;Madhavi Latha, G.
    • Geomechanics and Engineering
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    • v.4 no.4
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    • pp.251-262
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    • 2012
  • Triaxial tests are essential to estimate the shear strength properties of the soil or rock. Normally triaxial tests are carried out on samples of 38 mm diameter and 76 mm height. Granular materials, predominantly used in base/sub-base construction of pavements or in railways have size range of 60-75 mm. Determination of shear strength parameters of those materials can be made possible only through triaxial tests on large diameter samples. This paper describes a large diameter cyclic triaxial testing facility set up in the Geotechnical Engineering lab of Indian Institute of Science. This setup consists of 100 kN capacity dynamic loading frame, which facilitates testing of samples of up to 300 mm diameter and 600 mm height. The loading ram can be actuated up to a maximum frequency of 10 Hz, with maximum amplitude of 100 mm. The setup is capable of carrying out static as well as dynamic triaxial tests under isotropic, anisotropic conditions with a maximum confining pressure of 1 MPa. Working with this setup is a difficult task because of the size of the sample. In this paper, a detailed discussion on the various problems encountered during the initial testing using the equipment, the ideas and solutions adopted to solve them are presented. Pilot experiments on granular sub-base material of 53 mm down size are also presented.

A Study on the Weight Lightening Algorithm of 3-Dimensional Large Object based on Spatial Data LOD (공간데이터 LOD 기반 3차원 대용량 객체의 경량화 알고리즘 연구)

  • Na, Joon Yeop;Hong, Chang Hee
    • Spatial Information Research
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    • v.21 no.6
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    • pp.1-9
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    • 2013
  • Recently, Construction information is being changed from CAD to BIM, and GIS is extending from outdoor to indoor information. In these circumstances, the needs of continuous use of construction information linked with GIS are growing constantly in stages of maintenance, operation and service as well as planning, design and construction. To this end, it is essential element to represent 3-dimensional large object efficiently in establishing BIM-GIS interoperability platform by combination of construction and spatial information. In this study, we design spatial data LOD for making spatial object and texture by level, and develop weight lightening algorithm of large spatial object.

An Experimental Assessment of Combustion Stability of Coaxial Swirl Injectors and an Impinging Injector through Simulating Combustion Test (상압기상연소시험을 통한 동축형 스월 분사기와 충돌형 분사기의 연소 안정성 평가)

  • Park, Junhyeong;Kim, Hongjip
    • Journal of the Korean Society of Combustion
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    • v.22 no.1
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    • pp.46-52
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    • 2017
  • High-frequency combustion instabilities may occur during the development of feasible engine combustors. These instabilities can result in irreparable damages to the wall of combustors or the degradation of engine performance. So, it is essential to identify injectors that have high stability characteristics during the early stages of development. The objective of present study was to assess the stability of coaxial injectors and an impinging injector with different recess lengths in order to develop stable injectors optimally. Stability margin was evaluated based on the distance from operating condition to the unstable regions. A simulating combustion test method was used to analyze the stability of injectors. A small-scale combustion chamber was designed to simulate the first tangential acoustic mode of the actual combustor. Gaseous oxygen and a mixture of methane and propane were used as simulant propellants to satisfy their flow similarity to the actual propellants of a combustor in a liquid rocket combustor. The results indicated that injectors having small recess lengths showed relatively large combustion stability margins. For the injectors of large recess lengths, instability regions with large and super-large amplitude oscillations were observed. Thus, injector with shorter recess lengths had a higher stability than that of longer one due to the different mixing processes.

Prediction of Tensile Strength of a Large Single Anchor Considering the Size Effect

  • Kim, Kang-Sik;An, Gyeong-Hee;Kim, Jin-Keun;Lee, Kwang-soo
    • KEPCO Journal on Electric Power and Energy
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    • v.5 no.3
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    • pp.201-207
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    • 2019
  • An anchorage system is essential for most reinforced concrete structures to connect building components. Therefore, the prediction of strength of the anchor is very important issue for safety of the structures themselves as well as structural components. The prediction models in existing design codes are, however, not applicable for large anchors because they are based on the small size anchors with diameters under 50 mm. In this paper, new prediction models for strength of a single anchor, especially the tensile strength of a single anchor, is developed from the experimental results with consideration of size effect. Size effect in the existing models such as ACI or CCD method is based on the linear fracture mechanics which is very conservative way to consider the size effect. Therefore, new models are developed based on the nonlinear fracture mechanics rather than the linear fracture mechanics for more reasonable prediction. New models are proposed by the regression analysis of the experimental results and it can predict the tensile strength of both small and large anchors.

Development of Smart ICT-Type Electronic External Short Circuit Tester for Secondary Batteries for Electric Vehicles (전기자동차용 2차전지를 위한 스마트 ICT형 전자식 외부 단락시험기 개발)

  • Jung, Tae-Uk;Shin, Byung-Chul
    • Journal of the Korean Society of Industry Convergence
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    • v.25 no.3
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    • pp.333-340
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    • 2022
  • Recently, the use of large-capacity secondary batteries for electric vehicles is rapidly increasing, and accordingly, the demand for technologies and equipment for battery reliability evaluation is increasing significantly. The existing short circuit test equipment for evaluating the stability of the existing secondary battery consists of relays, MCs, and switches, so when a large current is energized during a short circuit, contact fusion failures occur frequently, resulting in high equipment maintenance and repair costs. There was a disadvantage that repeated testing was impossible. In this paper, we developed an electronic short circuit test device that realizes stable switching operation when a large-capacity power semiconductor switch is energized with a large current, and applied smart ICT technology to this electronic short circuit stability test system to achieve high speed and high precision through communication with the master. It is expected that the inspection history management system based on data measurement, database format and user interface will be utilized as essential inspection process equipment.