• Journal of the Korean Institute of Landscape Architecture
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• v.51 no.1
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• pp.85-97
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• 2023

Seoul Boramae Park was opened on May 5, 1986, after the Republic of Korea Air Force Academy relocated to Cheongju City in 1985. This study aims to examine the birth and evolution of Seoul Boramae Park and diagnose the park's value being transformed from the former site of the Air Force Academy. Policy reports and newspaper data were analyzed as a research method, focusing on Seoul public records. The study results are as follows. First, Seoul Boramae Park is a large-scale park created before the policy for parks on relocated sites we enacted. Second, Seoul Boramae Park has historical value as an urban park where memories and traces of the Air Force Academy overlap. Third, Seou Boramae Park contributed to regional change by promoting the public value of parks created on the relocated sites with an urban planning method. Seoul Boramae Park has implications for Korean landscape history as a case of securing large green areas in Seoul and presenting its function and roles as a park created on a relocated site.

• Computers and Concrete
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• v.25 no.6
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• pp.517-523
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• 2020

An experimental system on three point bending notched beams was established to study the fracture process of concrete. In this system, the acoustic emission (AE) was used to build the cumulative generation order (AGO) and dynamically track the process of microcrack evolution in concrete. A grey-cusp catastrophe model was built based on AE parameters. The results show that the concrete beams have significant catastrophe characteristic. The developed grey-cusp catastrophe model, based on AGO, can well describe the catastrophe characteristic of concrete fracture process. This study also provides a theoretical and technical support for the application of AE in concrete fracture prediction.

• East Asian Economic Review
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• v.20 no.3
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• pp.311-338
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• 2016

In the race for establishing trading architecture consistent with new landscape of the global economy, the US is ahead of the game by concluding the Trans Pacific Partnership Agreement with 11 countries. To make it reality, the ratification is essential. In the battle for ratification in the US, declining globalism confronts rising protectionism. This paper models the ratification process as contest between globalism and protectionism, and analyzes the optimal timing for ratification. Based on this framework, various ratification scenarios are analyzed. The paper argues less likelihood for the lame-duck session passage and more likelihood for prolonged and protracted delay, due to changing political dynamics and declining intellectual support for globalism. Hence, the future of Trans Pacific Partnership Agreement may prove different, compared to the North American Free Trade Agreement and the Korea-US Free Trade Agreement, both of which were renegotiated and ratified eventually. Then, the US would lose the first move advantage. The paper also discusses strategic implications of delayed ratification on the evolution of trading architecture in East Asia.

• Animal Systematics, Evolution and Diversity
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• v.37 no.4
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• pp.330-334
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• 2021

The genus Clubiona Latreille, 1804 is the most diverse and largest one in the family Clubionidae Wagner, 1887. Twenty-nine species of the genus have been described in various ecosystems from Korea to date. Clubiona semicircularis Tang, Song and Zhu, 2005 which was formerly only known in China and Clubiona ansa n. sp. were collected with a sweep net on the foliage of the shrubs in mixed forests from mountains and agricultural landscape during a seasonal survey of the spider fauna in Korea. This study describes these two species with a diagnosis, measurements, and morphological illustrations. In addition, the female of C. semicircularis is described with a diagnosis for the first time from the present study.

• Tuberculosis and Respiratory Diseases
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• v.82 no.3
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• pp.179-189
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• 2019

Although recent advances in molecular targeted therapy and immuno-oncology have revolutionized the landscape of lung cancer therapeutics, cytotoxic chemotherapy remains an essential component of lung cancer treatment. Extensive evidence has demonstrated the clinical benefit of chemotherapy, either alone or in combination with other treatment modalities, on survival and quality of life of patients with early and advanced lung cancer. Combinational approaches with other classes of anti-neoplastic agents and new drug-delivery systems have revealed promising data and are areas of active investigation. Chemotherapy is recommended as a standard of care in patients that have progressed after tyrosine kinase inhibitors or immune checkpoint inhibitors. Chemotherapy remains the fundamental means of lung cancer management and keeps expanding its clinical implication. This review will discuss the current position and future role of chemotherapy, and specific consideration for its clinical application in the era of precision medicine.

• BMB Reports
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• v.54 no.1
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• pp.70-88
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• 2021

Immunotherapy has revolutionized the landscape of cancer treatment and become a standard pillar of the treatment. The two main drivers, immune checkpoint inhibitors and chimeric antigen receptor T cells, contributed to this unprecedented success. However, despite the striking clinical improvements, most patients still suffer from disease progression because of the evolution of primary or acquired resistance. This mini-review summarizes new treatment options including novel targets and interesting combinational approaches to increase our understanding of the mechanisms of the action of and resistance to immunotherapy, to expand our knowledge of advances in biomarker and therapeutics development, and to help to find the most appropriate option or a way of overcoming the resistance for cancer patients.

• BMB Reports
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• v.55 no.7
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• pp.305-315
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• 2022

Transposable elements (TEs) are DNA sequences capable of mobilization from one location to another in the genome. Since the discovery of 'Dissociation (Dc) locus' by Barbara McClintock in maize (1), mounting evidence in the era of genomics indicates that a significant fraction of most eukaryotic genomes is composed of TE sequences, involving in various aspects of biological processes such as development, physiology, diseases and evolution. Although technical advances in genomics have discovered numerous functional impacts of TE across species, our understanding of TEs is still ongoing process due to challenges resulted from complexity and abundance of TEs in the genome. In this mini-review, we briefly summarize biology of TEs and their impacts on the host genome, emphasizing importance of understanding TE landscape in the genome. Then, we introduce recent endeavors especially in vivo retrotransposition assays and long read sequencing technology for identifying de novo insertions/TE polymorphism, which will broaden our knowledge of extraordinary relationship between genomic cohabitants and their host.

• Korean Journal of Radiology
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• v.25 no.2
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• pp.126-133
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• 2024

Large language models (LLMs) have revolutionized the global landscape of technology beyond natural language processing. Owing to their extensive pre-training on vast datasets, contemporary LLMs can handle tasks ranging from general functionalities to domain-specific areas, such as radiology, without additional fine-tuning. General-purpose chatbots based on LLMs can optimize the efficiency of radiologists in terms of their professional work and research endeavors. Importantly, these LLMs are on a trajectory of rapid evolution, wherein challenges such as "hallucination," high training cost, and efficiency issues are addressed, along with the inclusion of multimodal inputs. In this review, we aim to offer conceptual knowledge and actionable guidance to radiologists interested in utilizing LLMs through a succinct overview of the topic and a summary of radiology-specific aspects, from the beginning to potential future directions.

• Journal of the Korean Institute of Landscape Architecture
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• v.47 no.5
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• pp.41-48
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• 2019

Our daily lives are changing at a rapid pace and the concept of smart city is spreading, as the information communication technologies apply to various fields. However, efforts to prepare for changes in society due to technological evolution are insufficient in the field of landscape architecture. The purposes of this study are to explore the concept of smart parks, to investigate how smart technology has been applied to parks, and to identify the users' perception and satisfaction on smart park services. To this end, we conducted literature review, focus group interviews with experts, and a questionnaire survey with 180 users of the IoT See pilot smart park in Daegu. Smart parks can, as a result, be defined as sustainable parks that improve users' experience in parks and solve social and environmental problems faced by utilizing various high technology. Smart technologies introduced at the park so far have been mostly focused on safety and environmental areas, including AI CCTV, smart street lamp, and fine dust warning devices. The results of survey showed that not many users were aware of the smart services the park provided due to the lack of public communication as well as the nature of maintenance-oriented smart services. The survey also found that AR services for the education of historic parks were the least utilized, while solar power benches and WiFi service were most preferred by the park users. In conclusion, smart technologies need to be integrated with diverse park contents more centered user needs, providing services to enhance safety and environmental management in order to develop user-oriented smart parks.

• Journal of the Korean Geographical Society
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• v.39 no.5 s.104
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• pp.722-734
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• 2004

Longitudinal profiles of bedrock rivers play a fundamental role in landscape history by setting the boundary conditions for landform evolution. Longitudinal profiles are changed with climatic conditions, lithology and tectonic movements. Tectonic movement is an important factor controlling longitudinal profiles, especially in tectonically active area where uplift rates are regarded as a major factor controlling channel gradient. However study on bedrock channel has made little progress, because controls over bedrock river incision are yet to be clarified. Previous numerical simulations have used a simple diffusion model, which links together the overall processes of bedrock channel erosion as in other landform evolution models. In this study, previous bedrock incision models based on physical processes (especially abrasion) are reviewed and new modifications are introduced. Using newly formulated numerical model, the role of spatial pattern and intensity of tectonic uplift on changes in river longitudinal profile was simulated and discussed.