• Food Science of Animal Resources
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• v.38 no.2
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• pp.291-301
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• 2018

To shorten the production cycle of Zaodan, this study first pickled Zaodan by a novel technology - vacuum decompression technology. Vacuum decompression technology could reduce the pickling time of Zaodan from 20 wk to about 9 wk. The protein content, moisture and pH of the Zaodan egg white gradually decreased with a concomitant increase in salt during the pickling process. The total sulfhydryl group (SH) group content of the egg white proteins was increased to $2.43{\times}10^{-3}mol/L$ after being pickled for 30 d, whereas the content of disulphide bonds (SS) was reduced to $23.35{\times}10^{-3}mol/L$. The surface hydrophobicity was lowest after pickling for 30 d. In addition, great changes occurred in the secondary structure of the egg white proteins after pickling for 20 d. The disappearance of ovomucin was noticeable based on sodium dodecyl sulfate-polyacrylamide gel electrophoresis analysis.

• Journal of Technologic Dentistry
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• v.28 no.1
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• pp.177-198
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• 2006

This study purposed to offer basic data for safety education of the dental laboratory technology after the investigation of how much the students in the dept. of dental laboratory technology are aware of the danger of each instrument, equipment or laboratory procedure that they use during laboratory and how much they demand safety education for this. The objects for this study were 423 students who were in the dept. of dental laboratory technology. In this regard, four colleges which have the dept. of dental laboratory technology were randomly selected to do a questionnaire survey. SPSS 12.0 was used to analyze the collected data. The results were as follows: As for satisfaction with their major, the respondents answered Satisfied (59.1%), Average (35.5%) and Dissatisfied (5.4%). In terms of the production process of a partial denture, they considered casting, polishing the casting body, polishing denture and burn out were most dangerous in order. As for the production process of a full denture, what they regarded as the most dangerous in order was polishing denture, deflasking and wax wash. Regarding the laboratory procedures of porcelain material, casting, trimming casting body, polishing porcelain material and burn out were the most dangerous procedures that they perceived. With regard to materials for use, alcohol, polishing, metal and wire were the most dangerous ones they thought. As for the handling characteristics of each material, small towns showed a higher demand for safety of the handling characteristics of alcohol. In terms of school year and sex, juniors and girls had higher scores in the demand for safety of the handling characteristics of acid. Regarding the handling characteristics of each equipment and instrument, all of small towns, juniors and girls showed the highest demand for safety of the handling characteristics of alcohol lamps. With regard to scores in the demand for safety of other characteristics, all of small towns, juniors and girls had the highest demand for safety of emergency treatment. Concerning the demand for safety education by the completion of safety education, in terms of each material, highest was the demand for safety of acid from the group which completed safety education. In regard to equipments and instruments, when it came to the demand for safety of the handling characteristics of casting machine, the educated group's demand for safety of acid was higher. Regarding other characteristics, the group which was not educated gained higher scores in the demand for safety of emergency treatment. 11. In all areas(materials, machines and others), small towns, girls and juniors showed higher scores in the demand for safety. Based on the above results, it was found that when students conduct the laboratory of dental technology, they would think that many materials, instruments or equipments for use are very dangerous. However, safety education was not fully given to them. Regarding the scores in the damned for safety education, the highest was 4.16 and the lowest was 3.43, which suggests that the scores were generally very high. In this regard, it is necessary to continue delivering a systematic safety education of materials, equipments or instruments used during the laboratory of dental technology. Therefore, through the analysis of each material, instruments or facility used in every laboratory and each process, safety accident types and accident risk factors should be investigated to develop educational materials for this. Moreover, it is required to open safety education as a single course of study or insert safety contents of all materials and machines into the class of dental laboratory instrument or dental materials for the purpose of a systematic and thorough safety education to prevent a safety accident during laboratory.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.10
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• pp.139-146
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• 2016

The purpose of this study is to investigate the necessity of safety awareness and education regarding the use of laboratories, and to foster safety awareness during intramural and extracurricular activities in high schools. The study conducted a questionnaire to 290 eleventh grade students of three high schools located in Seoul. The collected data were statistically analyzed. The result illustrates that 64.8% of students have experienced safety education during a regular class, 6.6% have experienced accidents, and 68.0% have experienced safety education during field activities. The result concludes that there is a lack of prior safety education as well as overall low awareness on the necessity of safety education. In particular, students who have experienced safety education recognizes the necessity of emergency education regarding laboratory accident more than those who did not receive such education. Thus, a systematic management of laboratory safety education and multilateral management measures for students' safety are required. There is a relatively high correlation between safety intention of R&D and Education factors and Community and Laboratory Safety Education. As much as there is a high safety demand regarding the laboratory instruments and experiment, it shows high intention of safety lab operation as well as count measurement of lab accident. This study recommends developing a laboratory safety education program and management methods appropriate for high school students.

• Journal of the Korean Society of Safety
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• v.25 no.4
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• pp.36-41
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• 2010

This paper seeks to survey and analyze the status of obligatory execution from key institutional aspects that have taken effect according to laws on creating safe environment for laboratory and of general details such as the level of satisfaction on the part of people engaged in research activity regarding the laws after they have taken effect. The subjects of this study were MA and PhD graduate students in science and engineering who are primarily involved in research. This questionnaire survey was focused on finding basic data required for safety education for researcher and for efficient safety management by examining the correlation between education time and level of satisfaction. The collected data were analyzed by using frequency analysis, descriptive statistics, one way anova by SPSS12 package. The results obtained by this study are as follow. 1) Awarences of safety management rules, ordinary inspection, safety education were around 70% and other law clauses were around 50%. 2) The general satisfaction after the Laboratory Safety Act enforcement was usual level with 4.72 points in 7. 3) Researchers demanded ordinary inspection and protective equipment in a safe environmental composition. 4) The safety education time for improvement of a safe consciousness level was needed 12h or 24h at 1 years.

• Journal of Microbiology and Biotechnology
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• v.29 no.1
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• pp.160-170
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• 2019

The lactic acid bacteria species Lactobacillus plantarum (L. plantarum) has been used extensively for vaccine delivery. Considering to the critical role of dendritic cells in stimulating host immune response, in this study, we constructed a novel CD11c-targeting L. plantarum strain with surface-displayed variable fragments of anti-CD11c, single-chain antibody (scFv-CD11c). The newly designed L. plantarum strain, named 409-aCD11c, could adhere and invade more efficiently to bone marrow-derived DCs (BMDCs) in vitro due to the specific interaction between scFv-CD11c and CD11c located on the surface of BMDCs. After incubation with BMDCs, the 409-aCD11c strain harboring a eukaryotic vector pValac-GFP could lead to more efficient expression of GFP compared with wild-type strains shown by flow cytometry analysis, indicating the enhanced translocation of pValac-GFP from L. plantarum to BMDCs. Similar results were also observed in an in vivo study, which showed that oral administration resulted in efficient expression of GFP in both Peyer's patches (PP) and mesenteric lymph nodes (MLNs) within 7 days after the last administration. In addition, the CD11c-targeting strain significantly promoted the differentiation and maturation of DCs, the differentiation of $IL-4^+$ and $IL-17A^+$ T helper (Th) cells in MLNs, as well as production of $B220^+$ $IgA^+$ B cells in the PP. In conclusion, this study developed a novel DC-targeting L. plantarum strain which could increase the ability to deliver eukaryotic expression plasmid to host cells, indicating a promising approach for vaccine study.

• Journal of Technologic Dentistry
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• v.27 no.1
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• pp.131-153
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• 2005

The purpose of this study was to identify the accidents happened in the college dental laboratory technique classes and to realize the level of safety education for the dental laboratory technique major students. The research data were collected from a self-administered survey distributed to the conveniently selected college students whose majors were dental laboratory technology in Suwon, Daejeon, Daegu, Kimcheon, and Icsan. The study participants were 422 freshmen, sophomore and junior students in the selected cities. All collected survey responses were encoded and analyzed in SPSS 12.0. The findings were as follows. 1. The students who had any accidents in their laboratory classes were 36% and the other 64% answered 'no.' 2. Most injuries which the participants had were not significant. 3. The medical treatment periods of most injury cases were less than one week; however, approximately 20% of the self-reported injury cases reported that their treatment periods were longer than one week. 4. The body parts frequently injured from accidents were hands with 84.7% and arms, eyes, face, head, and legs in order. 5. Concerning the materials involved in the laboratory classes, most accidents happened when working with wax in 59.9%, with plaster in 52.3%, with wire in 39.8%, with alcohol in 34.6%, and casting iron in 22.2% in order. 6. The accident-prone laboratory methods were polishing with 53.5%, pickling or sanding with 17.4%, and casting or burning with 5.8% in order. 7. Most students wore their laboratory gowns well; however, few students wore mask before dust-involved jobs. Furthermore, only 57.1% students answered their laboratory fans worked during the polishing job. 8. Approximately 54% participant students answered that they took laboratory safety education when necessary only from the class instructors. 9. The 76.1% students responded that they needed laboratory safety education at least 1-2 times every semester. 10. The survey participants answered that the primary factors for injury prevention in their laboratory were taking safety education, wearing safety equipments, and providing safety-focused facilities. Concludingly, comprehensive evaluation and monitoring for potential risk factors from both the human side and the environment side should be continually provided to minimize the college laboratory accidents.

• Journal of Technologic Dentistry
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• v.39 no.3
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• pp.179-185
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• 2017

Purpose: It is intended to raise awareness of importance of protective equipment and necessity of safety education by examining the actual condition of measures to deal with accident, occurrence of injury, whether safety education is received or not, the actual condition of wearing protective equipment, and working environment of dental lab and dental technician. Methods: A self-administered survey was conducted for a total of 150 dental technologists. A chi-squared test and independent-samples t-test was carried out by using SPSS WIN Program (version 12.0) in order to analyze the actual condition of safety education according to work experience and position and whether injury occurred according to whether to wear protective equipment. Significance level was 0.05. Results: With regard to whether injury occurred according to whether safety education was received, there was 'receiving the safety education-injured (71.8%)', 'not receiving the safety education-injured (79.7%)', 'receiving the safety education-not injured (28.2%)', and 'not receiving the safety education-not injured (20.3%)'. The statistical results of injury occurrence according to safety education were not significant. With regard to whether to be injured according work experience, there was 'less than 10 years-injured (68.4%)', 'less than 10 years- not injured (31.6%)', '10 years or above-injured (89.1%)', and '10 years or above-not injured (10.9%)'. The statistical results of injury occurrence according to work experience were significant (p<0.001). Conclusion: Dental lab and specialized agencies should continue to be interested in periodic safety training, recommending wearing protective equipment and personal protective equipment support and so on.

• Nuclear Engineering and Technology
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• v.55 no.8
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• pp.2723-2733
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• 2023

Transuranic nuclides (such as ²³⁸Pu, ²⁵²Cf, ²⁴⁹Bk, etc.) have a wide range of application in industry, medicine, agriculture, and other fields. However, due to the complex conversion chain and remarkable fission losses in the process of transuranic nuclides production, the generation amounts are extremely low. High flux reactor with high neutron flux and flexible irradiation channels, is regarded as the promising candidate for producing transuranic nuclides. It is of great significance to increase the conversion ratio of transuranic nuclides, resulting in higher efficiency and better economy. In this paper, we perform an optimization design evaluation of producing transuranic nuclides in high flux reactor, which includes optimization design of irradiation target and influence study of reactor core loading. It is demonstrated that the production rate increases with appropriately determined target material and target structure. The target loading scheme in the irradiation channel also has a significant influence on the production of transuranic nuclides.

• Structural Engineering and Mechanics
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• v.56 no.4
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• pp.549-567
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• 2015

A first-order moment method (FORM) reliability analysis is commonly used for structural stability analysis. It requires the values and partial derivatives of the performance to function with respect to the random variables for the design. These calculations can be cumbersome when the performance functions are implicit. A Gaussian process (GP)-based response surface is adopted in this study to approximate the limit state function. By using a trained GP model, a large number of values and partial derivatives of the performance functions can be obtained for conventional reliability analysis with a FORM, thereby reducing the number of stability analysis calculations. This dynamic renewed knowledge source can provide great assistance in improving the predictive capacity of GP during the iterative process, particularly from the view of machine learning. An iterative algorithm is therefore proposed to improve the precision of GP approximation around the design point by constantly adding new design points to the initial training set. Examples are provided to illustrate the GP-based response surface for both structural and non-structural reliability analyses. The results show that the proposed approach is applicable to structural reliability analyses that involve implicit performance functions and structural response evaluations that entail time-consuming finite element analyses.

• Nuclear Engineering and Technology
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• v.55 no.1
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• pp.71-79
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• 2023

Air ingress incidents are major safety accidents in very-high-temperature reactors (VHTRs). Air containing a high volume fraction of oxygen may cause severe oxidation of core components at the VHTR, especially for the significantly thin alloy tube wall in the intermediate heat exchanger (IHE). The research objects of this study are Inconel 617 and Incoloy 800H, two candidate alloys for IHE in VHTR. The air ingress accident scenario is simulated with high-temperature air flow at 950 ℃. A continuous oxide scale was formed on the surfaces of both the alloys after the experiment. Because the oxide scale of Inconel 617 has a loose structure, whereas that of Incoloy 800H is denser, Inconel 617 exhibited significantly more severe internal oxidation than Incoloy 800H. Further, Inconel 617 showed a significant decrease in ultimate tensile strength and plasticity after aging for 200 h, whereas Incoloy 800H maintained its tensile properties satisfactorily. Through control experiment under vacuum, we preliminarily concluded that serious internal oxidation is the primary reason for the decline in the tensile properties of Inconel 617.