• Journal of Yeungnam Medical Science
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• v.22 no.2
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• pp.253-258
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• 2005

Generalized edema and hypoalbuminemia are relatively common presenting manifestations in many clinical situations. The differential diagnosis of hypoalbuminemia include: Kwashiorkor, synthetic dysfunction of the liver, and excessive protein loss as in nephrotic syndrome. In systemic lupus erythematosus (SLE), hypoalbuminemia and generalized edema are most commonly due to protein loss associated with lupus nephritis; gastrointestinal involvement is uncommon, and therefore protein loss through the gastrointestinal tract is quite rare. We report a case of a protein losing enteropathy (PLE) associated with SLE. The patient was referred to our hospital for generalized edema, arthralgia and facial rash. After clinical evaluation, the patient met the criteria for the SLE diagnosis; hypoalbuminemia with general edema was consistent with a protein losing enteropathy. After two weeks of therapy with parenteral high dose glucocorticoid, the patients was improved in laboratory findings as well as clinical symptoms.

• The Korean Journal of Legal Medicine
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• v.40 no.2
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• pp.61-64
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• 2016

Ehlers-Danlos syndrome type IV (EDS IV) is a hereditary disorder of the connective tissue, characterized by easy bruising, thin skin with visible veins, and spontaneous rupture of the large arteries, uterus, or bowel. EDS IV is caused by mutations of the gene for type III procollagen (COL3A1), resulting in insufficient collagen production or a defect in the structure of collagen. EDS IV can have fatal complications such as the rupture of great vessels or organs, which can cause hemorrhaging and sudden unexpected death. Here, we report a case of a 43-year-old female who collapsed after a struggle with a neighbor. In this patient, the bifurcation of the bilateral common iliac artery ruptured, with no evidence of trauma, inflammation, or atherosclerosis. Genetic analysis of COL3A1 showed the presence of a c.2771G>A (p.Gly924Arg) mutation, which may be associated with EDS IV. The forensic pathologist should consider the possibility that the spontaneous visceral or arterial rupture was caused by EDS IV. Genetic analysis is not currently a routine procedure during autopsy. However, in this case, we suggest that the patient possibly had an underlying EDS IV condition, and we recommended family members of the deceased to seek genetic analysis and counseling.

• Parasites, Hosts and Diseases
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• v.57 no.5
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• pp.461-467
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• 2019

Avian trematodes, Urogonimus turdi (Digenea: Leucochloridiidae), were collected from the intestine of wild birds, Zoothera aurea, 2013-2017 in the Daejeon Metropolitan City, Korea. The body was ellipsoidal, attenuated and/or round ends, 1,987-2,120 long and $819-831{\mu}m$ wide. The oral sucker was subterminal, rounded anteriorly, and $308-425{\times}351-432{\mu}m$ in size; the prepharynx and esophagus were almost lacking; pharynx was well-developed, $142-179{\times}78-170{\mu}m$ in size; intestine narrow, bifurcating just after pharynx, ascending to the oral sucker before looping posteriorly and terminating near the posterior end; ventral sucker larger, in almost median, $536-673{\times}447-605{\mu}m$ and approximately 1.5 times larger than oral sucker. A phylogenetic tree constructed with 18S ribosomal RNA showed inter- and intraspecific relationships. Based on these morphological and molecular findings, we report here a U. turdi from White's thrushes in Korea.

• Nuclear Engineering and Technology
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• v.42 no.4
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• pp.339-364
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• 2010

Following a joint OECD/NEA-IAEA-sponsored meeting to define the current role and future perspectives of the application of Computational Fluid Dynamics (CFD) to nuclear reactor safety problems, three Writing Groups were created, under the auspices of the NEA working group WGAMA, to produce state-of-the-art reports on different aspects of the subject. The work of the second group, WG2, was to document the existing assessment databases for CFD simulation in the context of Nuclear Reactor Safety (NRS) analysis, to gain a measure of the degree of quality and trust in CFD as a numerical analysis tool, and to take initiatives to extend the existing databases. The group worked over the period of 2003-2007 and produced a final state-of-the-art report. The present paper summarises the material gathered during the study, illustrating the points with a few highlights. A total of 22 safety issues were identified for which the application of CFD was considered to potentially bring real benefits in terms of better understanding and increased safety. A list of the existing databases was drawn up and synthesised, both from the nuclear area and from other parallel, non-nuclear, industrial activities. The gaps in the technology base were also identified and discussed. In order to initiate new ways of bringing experimentalists and numerical analysts together, an international workshop -- CFD4NRS (the first in a series) -- was organised, a new blind benchmark activity was set up based on turbulent mixing in T-junctions, and a Wiki-type web portal was created to offer online access to the material put together by the group giving the reader the opportunity to update and extend the contents to keep the information source topical and dynamic.

• Advances in aircraft and spacecraft science
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• v.4 no.3
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• pp.281-296
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• 2017

The axial-injection end-burning hybrid rocket proposed twenty years ago by the authors recently recaptured the attention of researchers for its virtues such as no ${\zeta}$ (oxidizer to fuel mass ratio) shift during firing and good throttling characteristics. This paper is the first report verifying these virtues using a laboratory scale motor. There are several requirements for realizing this type of hybrid rocket: 1) high fuel filling rate for obtaining an optimal ${\zeta}$; 2) small port intervals for increasing port merging rate; 3) ports arrayed across the entire fuel section. Because these requirements could not be satisfied by common manufacturing methods, no previous researchers have conducted experiments with this kind of hybrid rocket. Recent advances in high accuracy 3D printing now allow for fuel to be produced that meets these three requirements. The fuel grains used in this study were produced by a high precision light polymerized 3D printer. Each grain consisted of an array of 0.3 mm diameter ports for a fuel filling rate of 98% .The authors conducted several firing tests with various oxidizer mass flow rates and chamber pressures, and analysed the results, including ${\zeta}$ history, using a new reconstruction technique. The results show that ${\zeta}$ remains almost constant throughout tests of varying oxidizer mass flow rates, and that regression rate in the axial direction is a nearly linear function of chamber pressure with a pressure exponent of 0.996.

• Archives of Plastic Surgery
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• v.48 no.5
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• pp.518-523
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• 2021

Epignathus is a rare congenital orofacial teratoma that arises from the sphenoid region of the palate or the pharynx. It occurs in approximately 1:35,000 to 1:200,000 live births representing 2% to 9% of all teratomas. We present the case of a newborn of 39.4 weeks of gestation with a tumor that occupied the entire oral cavity. The patient was delivered by cesarean section. Oral resection was managed by pediatric surgery. Plastic surgery used virtual 3-dimensional models to establish the extension, and depth of the tumor. Bloc resection and reconstruction of the epignathus were performed. The mass was diagnosed as a mature teratoma associated with cleft lip and palate, nasoethmoidal meningocele that conditions hypertelorism, and a pseudomacrostoma. Tridimensional technology was applied to plan the surgical intervention. It contributed to a better understanding of the relationships between the tumor and the adjacent structures. This optimized the surgical approach and outcome.

• Neonatal Medicine
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• v.28 no.3
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• pp.133-138
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• 2021

Osteopetrosis refers to a group of genetic skeletal disorders characterized by osteosclerosis and fragile bones. Osteopetrosis can be classified into autosomal dominant, autosomal recessive, or X-linked forms, which might differ in clinical characteristics and disease severity. Autosomal recessive osteopetrosis, also known as malignant osteopetrosis, has an earlier onset, more serious clinical symptoms, and is usually fatal. We encountered a 1-day-old girl who was born full-term via vaginal delivery, which was complicated by meconium-stained amniotic fluid, cephalo-pelvic disproportion, and nuchal cord. Routine neonatal care was provided, in addition to blood tests and chest radiography to screen for sepsis, as well as skull radiography to rule out head injuries. Initial blood tests revealed hypocalcemia, which persisted on follow-up tests the next day. Radiographic examinations revealed diffusely increased bone density and a "space alien" appearance of the skull. Based on radiographic and laboratory findings, the infantile form of osteopetrosis was suspected and genetic testing for identification of the responsible gene. Eventually, a heterozygous mutation of the T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 (TCIRG1) gene (c.292C>T) was identified, making this the first reported case of neonatal-onset malignant osteopetrosis with TCIRG1 mutation in South Korea. Early-onset hypocalcemia is common and usually results from prematurity, fetal growth restriction, maternal diabetes, perinatal asphyxia, and physiologic hypoparathyroidism. However, if hypocalcemia persists, we recommend considering 'infantile of osteopetrosis' as a rare cause of neonatal hypocalcemia and performing radiographic examinations to establish the diagnosis.

• Clinical and Experimental Pediatrics
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• v.64 no.11
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• pp.575-581
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• 2021

Background: Toxocariasis is a zoonotic parasitic disease caused by Toxocara canis and Toxocara cati in humans. Various types of T. canis are important. Purpose: The current study aimed to investigate the prevalence of Toxocara spp. in pediatrics in the context of a systematic review and meta-analysis. Methods: The MEDLINE (PubMed), Web of Sciences, Embase, Google Scholar, Scopus, and Cumulative Index of Nursing and Allied Health databases were searched to identify peer-reviewed studies published between January 2000 and December 2019 that report the prevalence of Toxocara spp. in pediatrics. The evaluation of articles based on the inclusion and exclusion criteria was performed by 2 researchers individually. Results: The results of 31 relevant studies indicated that the prevalence of Toxocara spp. was 3%-79% in 10,676 cases. The pooled estimate of global prevalence of Toxocara spp. in pediatrics was 30 (95% confidence interval, 22%-37%; I²=99.11%; P=0.00). The prevalence was higher in Asian populations than in European, American, and African populations. Conclusion: Health policymakers should be more attentive to future research and approaches to Toxocara spp. and other zoonotic diseases to improve culture and identify socioeconomically important factors.

• Journal of Korean Public Health Nursing
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• v.35 no.1
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• pp.19-32
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• 2021

Purpose: This study was aimed to identify the influencing factors on the COVID-19 infection prevention behavior of adults residing in Gyeongsangnam-do by examining relationships between anxiety, health belief and COVID-19 infection prevention behavior. Methods: The participants of this study were recruited from a website, and the total number of participants was 186. The self-report questionnaires were distributed during July 2020. Results: Multiple regression analysis revealed the significant factors affecting the COVID-19 infection prevention behavior of adult residing in Gyeongsangnam-do were perceived barriers(��=-3.68, p<.001), perceived benefits(��=3.39, p=.001), perceived susceptibility(��=2.83, p=.005), sex(��=2.59, p=.010). The total explanatory power of the study variables for COVID-19 infection prevention behavior was 35.0%(F=17.61, p<.001). Conclusions: Based on these findings, in order to promote COVID-19 infection prevention behavior, there is needed to reduce obstacles for carrying out infection prevention behaviors, and develop multi-faceted promotional strategies for infection prevention behaviors.

• Journal of the Korea Convergence Society
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• v.10 no.2
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• pp.261-268
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• 2019

In this study, we report the effectiveness of an interprofessional patient safety education in impacting student knowledge, attitudes and self-confidence around interprofessional communication. Thirty third-year students took part in a six weeks education that included a 90 minutes lecture and group discussion. Self-administered questionnaire were used for examining knowledge, attitudes, self-confidence and interviewed about team communication. There was no change in the knowledge(p=>0.05) but the attitude and self-confidence improved significantly after the education(p=<0.05). Students also noted that the importance of collaboration with other occupational groups. The first implementation of the interprofessional patient safety education had a positive effect on student attitudes, self-confidence and interprofessional teamwork.