• Title/Summary/Keyword: laboratory lessons

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MULTI-SCALE MODELS AND SIMULATIONS OF NUCLEAR FUELS

  • Stan, Marius
    • Nuclear Engineering and Technology
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    • v.41 no.1
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    • pp.39-52
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    • 2009
  • Theory-based models and high performance simulations are briefly reviewed starting with atomistic methods, such as Electronic Structure calculations, Molecular Dynamics, and Monte Carlo, continuing with meso-scale methods, such as Dislocation Dynamics and Phase Field, and ending with continuum methods that include Finite Element and Finite Volume. Special attention is paid to relating thermo-mechanical and chemical properties of the fuel to reactor parameters. By inserting atomistic models of point defects into continuum thermo-chemical calculations, a model of oxygen diffusivity in $UO_{2+x}$ is developed and used to predict point defect concentrations, oxygen diffusivity, and fuel stoichiometry at various temperatures and oxygen pressures. The simulations of coupled heat transfer and species diffusion demonstrate that including the dependence of thermal conductivity and density on composition can lead to changes in the calculated centerline temperature and thermal expansion displacements that exceed 5%. A review of advanced nuclear fuel performance codes reveals that the many codes are too dedicated to specific fuel forms and make excessive use of empirical correlations in describing properties of materials. The paper ends with a review of international collaborations and a list of lessons learned that includes the importance of education in creating a large pool of experts to cover all necessary theoretical, experimental, and computational tasks.

Assessment of the Implementation of a Neutron Measurement System During the Commissioning of the Jordan Research and Training Reactor

  • Bae, Sanghoon;Suh, Sangmun;Cha, Hanju
    • Nuclear Engineering and Technology
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    • v.49 no.3
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    • pp.504-516
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    • 2017
  • The Jordan Research and Training Reactor (JRTR) is the first research reactor in Jordan, the commissioning of which is ongoing. The reactor is a 5-MWth, open-pool type, light-water-moderated, and cooled reactor with a heavy water reflector system. The neutron measurement system (NMS) applied to the JRTR employs a wide-range fission chamber that can cover from source range to power range. A high-sensitivity boron trifluoride counter was added to obtain more accurate measurements of the neutron signals and to calibrate the log power signals; the NMS has a major role in the entire commissioning stage. However, few case studies exist concerning the application of the NMS to a research reactor. This study introduces the features of the NMS and the boron trifluoride counter in the JRTR and shares valuable experiences from lessons learned from the system installation to its early commissioning. In particular, the background noise relative to the signal-to-noise ratio and the NMS signal interlock are elaborated. The results of the count rates with the neutron source and the effects of the discriminator threshold are summarized.

Laboratory Diagnosis of Coronavirus Disease 19 (COVID-19) in Korea: Current Status, Limitation, and Challenges (국내 중증 급성 호흡기 증후군 코로나 바이러스의 검사실 내 진단: 현재, 한계점 그리고 직면한 과제)

  • Song, Gi Seon;Lee, You-Rim;Kim, Sungmin;Kim, Wontae;Choi, Jungwon;Yoo, Dahyeon;Yoo, Jungyoung;Jang, Kyung-Tae;Lee, Jaewang;Jun, Jin Hyun
    • Korean Journal of Clinical Laboratory Science
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    • v.52 no.3
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    • pp.284-295
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    • 2020
  • In December 2019, the first coronavirus disease- 2019 (COVID-19) patient was reported in Wuhan, Hubei Province, China. Since then, the number of patients who suffered severe acute respiratory syndrome caused by the novel Coronavirus (SARS-CoV-2 or 2019-nCoV) has increased dramatically in Korea. This new variant virus induces pulmonary diseases, including cough, sore throat, rhinorrhea, dyspnea, and pneumonia. Because SARS-CoV-2 is an RNA virus, real-time reverse-transcriptase PCR has been used widely to diagnose COVID-19. As the Korea Centers for Disease Prevention and Control (KCDC) and Ministry of Food & Drug Safety (MFDS) approved emergency use authorization, clinical specimens collected from COVID-19 patients and even healthy people have been clinically diagnosed by laboratory medicine. Based on a literature search, this paper reviews the epidemiology, symptoms, molecular diagnostics approved by KCDC, a current diagnosis of COVID-19 in the laboratories, the difference between molecular and serological diagnosis, and guidelines for clinical specimens. In addition, the Korean guidelines of biosafety for clinical laboratory scientists are evaluated to prevent healthcare-associated infection. The author's experience and lessons as clinical laboratory scientists will provide valuable insights to protect the domestic and international health community in this COVID-19 pandemic around the world.

Case Study of Applying DO-278A for Advanced Surface Movement Guidance & Control System (DO-278A 표준을 적용한 A-SMGCS 개발 사례 연구)

  • Jo, Sanghoon;Lee, Hongseok;Kim, Jha-young;Yi, Jin-geun
    • Journal of Advanced Navigation Technology
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    • v.20 no.2
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    • pp.127-133
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    • 2016
  • This paper proposes a case study of applying to DO-278A, which is a software development standard of ground aviation equipment in communication, navigation, surveillance/air traffic management (CNS/ATM) domain, in order to develop software of Advanced surface movement, guidance and control system (A-SMGCS). It explains considerations to application of DO-278A standard, discusses how to tailor processes or requirements specified in DO-278A in detail, and explain tailored results. And it also summary problems or issues occurred during application of DO-278A, which can be appeared when DO-278A is applied to for the first time by any development part. These are required considerations in order to reduce trial and error. To the conclusion, it explains lessons learned from application of DO-278A and suggest how to solve these problems or issues.

Comparison of numerical and analytical solutions for reinforced soil wall shaking table tests

  • Zarnani, Saman;El-Emam, Magdi M.;Bathurst, Richard J.
    • Geomechanics and Engineering
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    • v.3 no.4
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    • pp.291-321
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    • 2011
  • The paper describes a simple numerical FLAC model that was developed to simulate the dynamic response of two instrumented reduced-scale model reinforced soil walls constructed on a 1-g shaking table. The models were 1 m high by 1.4 m wide by 2.4 m long and were constructed with a uniform size sand backfill, a polymeric geogrid reinforcement material with appropriately scaled stiffness, and a structural full-height rigid panel facing. The wall toe was constructed to simulate a perfectly hinged toe (i.e. toe allowed to rotate only) in one model and an idealized sliding toe (i.e. toe allowed to rotate and slide horizontally) in the other. Physical and numerical models were subjected to the same stepped amplitude sinusoidal base acceleration record. The material properties of the component materials (e.g. backfill and reinforcement) were determined from independent laboratory testing (reinforcement) and by back-fitting results of a numerical FLAC model for direct shear box testing to the corresponding physical test results. A simple elastic-plastic model with Mohr-Coulomb failure criterion for the sand was judged to give satisfactory agreement with measured wall results. The numerical results are also compared to closed-form solutions for reinforcement loads. In most cases predicted and closed-form solutions fall within the accuracy of measured loads based on ${\pm}1$ standard deviation applied to physical measurements. The paper summarizes important lessons learned and implications to the seismic design and performance of geosynthetic reinforced soil walls.

Quantifying the seismic resilience of two tall buildings designed using Chinese and US Codes

  • Tian, Yuan;Lu, Xiao;Lu, Xinzheng;Li, Mengke;Guan, Hong
    • Earthquakes and Structures
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    • v.11 no.6
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    • pp.925-942
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    • 2016
  • With ongoing development of earthquake engineering research and the lessons learnt from a series of strong earthquakes, the seismic design concept of "resilience" has received much attention. Resilience describes the capability of a structure or a city to recover rapidly after earthquakes or other disasters. As one of the main features of urban constructions, tall buildings have greater impact on the sustainability and resilience of major cities. Therefore, it is important and timely to quantify their seismic resilience. In this work, a quantitative comparison of the seismic resilience of two tall buildings designed according to the Chinese and US seismic design codes was conducted. The prototype building, originally designed according to the US code as part of the Tall Building Initiative (TBI) Project, was redesigned in this work according to the Chinese codes under the same design conditions. Two refined nonlinear finite element (FE) models were established for both cases and their seismic responses were evaluated at different earthquake intensities, including the service level earthquake (SLE), the design-based earthquake (DBE) and the maximum considered earthquake (MCE). In addition, the collapse fragility functions of these two building models were established through incremental dynamic analysis (IDA). Based on the numerical results, the seismic resilience of both models was quantified and compared using the new-generation seismic performance assessment method proposed by FEMA P-58. The outcomes of this study indicate that the seismic resilience of the building according to the Chinese design is slightly better than that according to the US design. The conclusions drawn from this research are expected to guide further in-depth studies on improving the seismic resilience of tall buildings.

Cytomorphologic Patterns of Breast Lesions in Sudanese Patients: Lessons Learned from Fine Needle Aspiration Cytology

  • Almobarak, Ahmed Omer;Elhassan, Taiseer Mohamed;Elhoweris, Mohamed Hassan;Awadalla, Heitham Mohammed;Elmadhoun, Wadie Mohamed Yasin;Ahmed, Mohamed Hassan
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.8
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    • pp.3411-3413
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    • 2014
  • Background: Cytology for breast lesions is a safe, rapid and cost-effective with a high specificity and sensitivity. Objective: To determine the cytomorphologic patterns of breast lesions identified among a group of Sudanese patients. Materials and Methods: This study included 759 patients undergoing either a fine needle aspiration FNA, nipple discharge (ND) smears or breast skin scraping (SS) at a cytology clinic in Khartoum. Clinical and demographic data were reviewed. Stained smears were categorized into: inadequate sample, normal breast, benign lesion, suspicious, or malignant neoplasm. Results: Of the 759 cases, 734 (96.71%) were FNA, 18 (2.37%) ND and 7 cases (0.92%) SS. For 28 cases, FNA was done under ultrasound guidance. Females were 720 (94.86%). Benign lesions were 423 (55.75%) and 248 (32.67%) were malignant and 77 (10.14%) of smears were normal without any detected abnormality. Ten (1.31%) cases were suspicious for malignancy, and only one case (0.13%) was reported as inadequate. Most lesions were observed among the age group 30 years and above. Conclusions: Most patients investigated have benign lesions, one third of cytological smears were malignant. FNAC is a useful tool for investigating breast lesions in limited-resource settings.

Beyond SARS-CoV-2: Lessons That African Governments Can Apply in Preparation for Possible Future Epidemics

  • Oboh, Mary Aigbiremo;Omoleke, Semeeh Akinwale;Imafidon, Christian Eseigbe;Ajibola, Olumide;Oriero, Eniyou Cheryll;Amambua-Ngwa, Alfred
    • Journal of Preventive Medicine and Public Health
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    • v.53 no.5
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    • pp.307-310
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    • 2020
  • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has placed unprecedented pressure on healthcare systems, even in advanced economies. While the number of cases of SARS-CoV-2 in Africa compared to other continents has so far been low, there are concerns about under-reporting, inadequate diagnostic tools, and insufficient treatment facilities. Moreover, proactiveness on the part of African governments has been under scrutiny. For instance, issues have emerged regarding the responsiveness of African countries in closing international borders to limit trans-continental transmission of the virus. Overdependence on imported products and outsourced services could have contributed to African governments' hesitation to shut down international air and seaports. In this era of emerging and re-emerging pathogens, we recommend that African nations should consider self-sufficiency in the health sector as an urgent priority, as this will not be the last outbreak to occur. In addition to the Regional Disease Surveillance Systems Enhancement fund (US$600 million) provided by the World Bank for strengthening health systems and disease surveillance, each country should further establish an epidemic emergency fund for epidemic preparedness and response. We also recommend that epidemic surveillance units should create a secure database of previous and ongoing pandemics in terms of aetiology, spread, and treatment, as well as financial management records. Strategic collection and analysis of data should also be a central focus of these units to facilitate studies of disease trends and to estimate the scale of requirements in preparation and response to any future pandemic or epidemic.

Urban Regeneration Plan for Mid-sized Cities Deploying the Concept of Smart City - Focused on the US Smart City Challenge in 2015 - (스마트시티 개념을 이용한 중소도시재생계획에 대한 연구 - 2015 미국 스마트시티챌린지 공모전을 중심으로 -)

  • Yoo, Seungho;Kim, Yongseung;Kim, Soyeon
    • Journal of the Architectural Institute of Korea Planning & Design
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    • v.35 no.9
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    • pp.29-40
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    • 2019
  • The concept of smart city is understood as an indispensable component of urban regeneration projects in small cities in terms of providing a better urban environment and efficient living systems with a limited budget. Recently, the Korean government revised the law that related to the construction of the smart city and started to implement the smart city concept not only to new-large urban development but also to small-existed regeneration projects. However, it is difficult for small and medium-sized cities that are suffering from the insufficient professional workforce; knowledge supports for high-tech and lack of professional networks to proceed smart city planning and project that containing regional characteristics. This paper aims to examine the effective way of urban regeneration for small and medium-sized cities through smart city planning and strategy. As an important case, this paper looks at the 'Smart City Challenge' competition that was hosted by the US Department of Transportation in 2015. It examines the background and operation process of the smart city challenge competition, and then analyses each city's strategy and characteristics of seven finalists. This paper highlights the several key lessons to Korean cities: 1) the importance of national government's support in financial and professional resources; 2) the cooperation with local governments and IT corporations which provides realistic and detailed technical solutions; 3) the holistic and integrated approach to urban regeneration starting from transportation issues; 4) the necessity of the government's clear visions and guidelines toward the smart city.

Development of Design Principles for Astronomical Observing Education Program Based on Authentic Inquiry (참탐구를 위한 천체 관측 교육 프로그램 설계 원리 개발)

  • Choi, Dong-Yeol;Ahn, Yumin
    • Journal of the Korean earth science society
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    • v.42 no.6
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    • pp.752-769
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    • 2021
  • Although astronomical observation has various educational effects and values, studies conducted in the context of earth science education have been relatively insufficient compared with other fields. In addition, few studies have been conducted on systematic design principles development guiding teachers in the application of practical astronomical observation education. In this study, we attempted to develop design principles for astronomical observation education programs for K-12 students and applied the program to the classes. The initial design principles were derived through literature research and revised through validation processes by eight experts. The final principles were confirmed based on the usability evaluation of two high school teachers, and they included 11 design principles and 27 detailed guidelines. In addition, an astronomical observation education program consisting of eight lessons was designed by applying the final design principle. This program was applied to after-school classes in high school, the responses of participating students were investigated. We anticipate our design principles can be used as a criterion for systematic design of various types of observation activities, including outdoor observations.