• Title/Summary/Keyword: lRE

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Convergence and the Riemann hypothesis

  • Lee, Jung-Seob
    • Communications of the Korean Mathematical Society
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    • v.11 no.1
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    • pp.57-62
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    • 1996
  • For $1 < p \leq 2$ it is shown that a certain sequence of functions converges to -1 in $L^{p-\varepsilon}(0, 1)$ for any small $\varepsilon > 0$ if and only if the Riemann zeta function satisfies $\zeta(s) \neq 0$ for $\sigma = Re s > 1/p$.

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Ginseng Saponin-Re and Coix lachrymajobi var. mayuen Regulate Obesity Related Genes Expressions, TNF-alpha, Leptin, Lipoprotein Lipase and Resistin in 3T3-L1 Adipocytes (지방세포 3T3-L1에 인삼 사포닌 Re와 의이인 추출액 처리시 비만관련 유전자인 TNF-α, lipoprotein lipase, leptin 및 resistin 발현 조절에 미치는 영향)

  • Kim, Sung-Ok
    • Journal of Life Science
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    • v.17 no.11
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    • pp.1523-1532
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    • 2007
  • In order to determine if the mRNA and protein expression levels of 3T3-L1 adipocytes are influenced by oriental medicines, adipocytes were treated with $100\;{\mu}g/ml$ of G-Re and aqueous extract of a Coix lachrymajobi var. mayuen (AEC) every other day for 12 days, respectively. The tumor necrosis factor alpha ($TNF-{\alpha}$). mRNA and protein expressions were suppressed markedly in treated mature adipocytes. Those of lipoprotein lipase (LPL) levels were found to increase gradually in preadipocytes differentiating into mature adipocytes. Those were higher than that of the untreated mature adipocytes. The treated adipocytes showed reduction of leptin expression levels, while in untreated mature adipocytes cell, those of levels were significantly higher after the conversion of preadipocytes into mature adipocytes. The resistin levels in the treated adipocytes were significantly decreased comparing to that of the untreated mature adipocytes. In conclusion, the expression levels of LPL, $TNF-{\alpha}$, leptin and resistin mRNA and proteins are shown to be regulated by G-Re and AEC, making them potential candidates for controlling fat mass related obesity.

Analysis of the GPS Meaconing Signal Generator for the Live GPS L1 Signal (Live GPS L1 재방송 기만신호 생성 분석)

  • Kim, Taehee;Sin, Cheonsig
    • Journal of Satellite, Information and Communications
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    • v.11 no.4
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    • pp.15-20
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    • 2016
  • In this paper, we developed the hardware GPS signal generator for generating a GPS L1 meaconing signal with Live GPS signal signals and analyzed the performance of meaconing signal generator thorough the experiment. Deception of the signal, such as a re-broadcast, it is an object of the user to provide false information so as not to receive location information and accurate time. The signal just rebroadcast has the features that can be easily deceive the receiver via a delay of no received signal to the signal processing through an antenna. In this paper, the hardware for generating a signal only these rebroadcast designed and manufactured, by re-sending the received Live GPS signals, to confirm the effect of the receiver. The maximum delay time is possible up to about 2.6msec, also, has been successfully tested to be moved to the position of re-broadcasting based on maturity antenna the position of the receiver through a spaced antenna.

Study on Cosmeceutical Activities from Fermented Ginseng Berry Extracts (진생베리 발효추출물의 화장품 약리활성)

  • Kim, Il-Chool
    • Journal of the Korean Applied Science and Technology
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    • v.37 no.1
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    • pp.28-37
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    • 2020
  • Ginseng berry contains a large amount of Ginsenoside Re and has anti-inflammatory, anticancer, hypoglycemic and whitening effects. In this study, Rhizopus Oligosporus strain was used to establish ginseng berry fermentation process and cosmetic pharmacological activity of ginseng berry fermented product was analyzed.. The electron donating ability of ginseng berry extract by fermentation shown 81% at 1,000 ㎍/mL concentration. The ABTS+ radical scavenging ability of shown 100.2% at 1,000 ㎍/mL concentration. The tyrosinase inhibitory effect which is related to skin-whitening, was 57% at the concentration of 1,000 ㎍/mL. The elastase inhibitory effect which is related to skin-wrinkle, was 47% at 1,000 ㎍/mL concentration. Also, the collagenase inhibition effect was 33% at 1,000 ㎍/mL concentration. From these results, ginseng berry extracts by fermentation is considered to have anti-inflammatory, anti-wrinkle effect and whitening effect. Therefor, ginseng berry fermented product is expected to be very useful as an anti-inflammatory and anti-aging cosmetic raw material.

The Influence of Maximal Aerobic Capacity on the Two Years Cardiac Related Re-Hospitalization in Patients with Heart Failure with Reduced Ejection Fraction in Korean Society

  • Ryu, Ho Youl;Hong, Do Sun;Kim, Tack Hoon
    • The Journal of Korean Physical Therapy
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    • v.31 no.5
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    • pp.322-327
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    • 2019
  • Purpose: This study examined the influence of the maximal aerobic capacity on the two-year cardiac-related re-hospitalization in patients with heart failure with a reduced ejection fraction (HFrEF) in Korean society. Methods: The maximal aerobic capacity of the study population (n=95, male 63%) was evaluated using a cardiopulmonary exercise (CPX) testing system. Each patient was followed up for two years to divide the HFrEF patients into two groups according to cardiac-related re-hospitalization: re-hospitalization (RH) group (n=29, 30%) and no re-hospitalization (NRH) group (n=66, 70%). Results: The relative peak $VO_2$ (mL/kg/min, p<0.001), exercise duration (p<0.001), respiratory exchange ratio ($VCO_2/VO_2$, p=0.001), systolic blood pressure (SBP) reserve (p=0.004), heart rate (HR) reserve (p=0.007), SBP max (p=0.02), and HR max (p=0.039) were significantly lower in the RH group than the NRH group during the CPX test. On the other hand, the ventilatory efficiency (VE/VCO2 slope, p=0.02) and age (p=0.022) were significantly higher in the RH group than in the NRH group. In binary logistic regression analysis, the relative peak $VO_2$ (p=0.001, Wald Chi-square 10.137) was the strongest predictive factor on cardiac-related re-hospitalization, which was followed by $VCO_2/VO_2$ (p=0.019, Wald Chi-square 5.54). On the other hand, age (p=0.063, Wald Chi-square 3.445) did not have a significant influence on cardiac related re-hospitalization. Conclusion: The maximal aerobic capacity, especially the relative peak $VO_2$, is the strongest factor on cardiac-related re-hospitalization within two years in patients with HFrEF in Korean society.

Le Lien de Causalit$\acute{e}$ et la Prescription Extinctive en Mati$\acute{e}$re de Responsabilit$\acute{e}$ M$\acute{e}$dicale en Droit Français (프랑스법상 의사책임분야(醫事責任分野)에서의 인과관계와 소멸시효론에 관한 소고)

  • Park, Soo-Gon
    • The Korean Society of Law and Medicine
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    • v.15 no.2
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    • pp.367-397
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    • 2014
  • Dans le contentieux m$\acute{e}$dical, il est difficile de prouver l'existence d'un lien de causalit$\acute{e}$ entre la faute m$\acute{e}$dicale et les pr$\acute{e}$judices subis par la victime. R$\acute{e}$partir bien de façon raisonnable la charge de la preuve du lien causal est alors une des questions pr$\acute{e}$occup$\acute{e}$es par la doctrine cor$\acute{e}$enne. La Cour supr$\hat{e}$me cor$\acute{e}$enne semble toutefois facilliter l'indemnisation des victimes dans les cas o$\grave{u}$ la responsabilit$\acute{e}$ du m$\acute{e}$decin a ${\acute{e}}t{\acute{e}}$ mise en cause, et cela en admettant des fois une solution op$\acute{e}$rant un renversement de la charge de la preuve du lien causal. Une telle attitude a ${\acute{e}}t{\acute{e}}$ m$\hat{e}$me affirm$\acute{e}$e dans un arr$\hat{e}$t rendu r$\acute{e}$cemment en cas de dommage caus$\acute{e}$ par le fait du produit de sant$\acute{e}$, notamment pour le cas de contamination virale par voie de transfusion. La Cour a $\acute{e}$galement reconnu que l'action se pr$\acute{e}$scrit $\grave{a}$ partir du moment de la consolidation du pr$\acute{e}$judice. Aux termes de cette $\acute{e}$tude, on pourra constater que le juge français reconna$\hat{i}$t aussi l'assouplissement de la charge de la preuve du lien de causalit$\acute{e}$ en mati$\acute{e}$re d'action m$\acute{e}$dicale. Il faudra toutefois souligner que le ph$\acute{e}$nom$\acute{e}$ne ne soit pas g$\acute{e}$n$\acute{e}$ralis$\acute{e}$ en droit français, d'autant plus que la pr$\acute{e}$somption de l'existence de la causalit$\acute{e}$ en la mati$\grave{e}$re a $\acute{e}$t$\acute{e}$ admise de mani$\grave{e}$re restrictive par la l$\acute{e}$gislation sp$\acute{e}$cifique. Tel $\acute{e}$tait notamment le cas pour les accidents de la contamination par le virus du sida ou de l'h$\acute{e}$patite C survenus apr$\grave{e}$s la transfusion. En d$\acute{e}$finitive, on peut dire qu'en droit français, le principe est maintenu en cas de manquement $\grave{a}$ une obligation de r$\acute{e}$sultat n$\acute{e}$e du contrat m$\acute{e}$dical, tandis que la Cour de cassation admet parfois en mati$\grave{e}$re de droit commun de la responsabilit$\acute{e}$ contractuelle la pr$\acute{e}$somption de causalit$\acute{e}$ en cas d'inex$\acute{e}$cution des obligations de r$\acute{e}$sultat. En fait, la pr$\acute{e}$somption de causalit$\acute{e}$ dans le contentieux m$\acute{e}$dical pourra mener les m$\acute{e}$decins $\grave{a}$ se diriger vers les traitements d$\acute{e}$fensifs. Cette situation peut m$\hat{e}$me conduire $\grave{a}$ emp$\hat{e}$cher le d$\acute{e}$veloppement de la science m$\acute{e}$dicale, enfin $\grave{a}$ une situation d$\acute{e}$savantageuse aux patients. Il y a alors lieu de se m$\acute{e}$fier des int$\acute{e}$r$\hat{e}$ts d$\acute{e}$s$\acute{e}$quilibr$\acute{e}$s entre le m$\acute{e}$decin et le patient. De ce point de vue, on peut estimer que le droit français donne des suggestions aux juristes cor$\acute{e}$ens dans la recherche des solutions plus ad$\acute{e}$quates en ce qui concerne la charge de la preuve du lien causal en mati$\acute{e}$re de responsabilit$\acute{e}$ m$\acute{e}$dicale.

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Uncertainty Evaluation of Nicotine in Cigarette Mainstream Smoke Using Two Point Re-calibration Method (두 점 교정법을 이용한 담배 연기 성분 중 니코틴 분석 결과에 대한 불확도 평가)

  • Kim Mi-Ju;Ji Sang-Un;Hwang Keon-Joong;Lee Moon-Soo;Cho Sung-Eel
    • Journal of the Korean Society of Tobacco Science
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    • v.26 no.2 s.52
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    • pp.168-178
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    • 2004
  • Uncertainty of final measurement results considering main uncertainty sources being in nicotine of mainstream smoke was estimated. This study was accomplished by using the ISO 'The Guide to the Expression of Uncertainty in Measurement'. Using the two point re-calibration method, uncertainty for nicotine concentration was calculated considering the uncertainty sources of each step. The concentration and uncertainty of nicotine in mainstream smoke was estimated as $153.95{\pm}17.84\;{\mu}g/mL\;(0.77\pm0.089 mg/cig)$. The expanded uncertainty was $17.84 {\mu}g/mL(\pm0.089 mg/cig).$ The reported expanded uncertainty of the measurement is stated as the standard uncertainty of measurement multiplied by a coverage factor of 2, which for a normal distribution corresponds to a coverage probability of approximately $95\%$ The former expression indicates the conversion concentration into the sample.

Inhibitory Effects of Ginsenoside Re Isolated from Ginseng Berry on Histamine and Cytokine Release in Human Mast Cells and Human Alveolar Epithelial Cells

  • Bae, Hye-Min;Cho, Ok-Sun;Kim, Shin-Jung;Im, Byung-Ok;Cho, Soon-Hyun;Lee, Se-Na;Kim, Myung-Gyou;Kim, Kyung-Tack;Leem, Kang-Hyun;Ko, Sung-Kwon
    • Journal of Ginseng Research
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    • v.36 no.4
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    • pp.369-374
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    • 2012
  • The berry of Panax ginseng significantly inhibited the histamine releases at the concentration of $30{\mu}g/mL$ (p<0.05) and $10{\mu}g/mL$ (p<0.01). The ginsenoside Re from ginseng berry was found out to have a potent effect in the experiment of histamin and cytokine release.

Analysis of Ginsenoside Composition of Ginseng Berry and Seed

  • Ko, Sung-Kwon;Bae, Hye-Min;Cho, Ok-Sun;Im, Byung-Ok;Chung, Sung-Hyun;Lee, Boo-Yong
    • Food Science and Biotechnology
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    • v.17 no.6
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    • pp.1379-1382
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    • 2008
  • This study was performed to provide basic information that can be used to differentiate Korean ginseng (Panax ginseng CA. Meyer) berry and seed from American ginseng (Panax quinquefolium L.) seed. Total ginsenoside contents of Korean ginseng berry, Korean ginseng seed, and American ginseng seed were 9.09, 3.30, and 4.06%, respectively. Total ginsenoside content of Korean ginseng berry was about 2.2 to 2.7 times higher than those of Korean ginseng seed and American ginseng seed. Particularly ginsenoside Re content of 4-year cultivated Korean ginseng berry (5.99%) was about 3.6 to 5.4 times higher than that of 4-year cultivated Korean ginseng seed (1.65%) and 4-year cultivated American ginseng seed (1.10%). The contents of total ginsenoside and ginsenoside Re of Korean ginseng berry were about 4.8 and 28 times higher, respectively, than those of 4-year cultivated Korean ginseng root. In general the contents of total ginsenoside and ginsenoside Re of Korean ginseng berry were significantly higher than those of Korean ginseng seed and American ginseng seed.

Estimation of Design Rainfall by the Regional Frequency Analysis using Higher Probability Weighted Moments and GIS Techniques (III) - On the Method of LH-moments and GIS Techniques - (고차확률가중모멘트법에 의한 지역화빈도분석과 GIS기법에 의한 설계강우량 추정 (III) - LH-모멘트법과 GIS 기법을 중심으로 -)

  • 이순혁;박종화;류경식;지호근;신용희
    • Magazine of the Korean Society of Agricultural Engineers
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    • v.44 no.5
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    • pp.41-53
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    • 2002
  • This study was conducted to derive the regional design rainfall by the regional frequency analysis based on the regionalization of the precipitation suggested by the first report of this project. According to the regions and consecutive durations, optimal design rainfalls were derived by the regional frequency analysis for L-moment in the second report of this project. Using the LH-moment ratios and Kolmogorov-Smirnov test, the optimal regional probability distribution was identified to be the Generalized extreme value (GEV) distribution among applied distributions. regional and at-site parameters of the GEV distribution were estimated by the linear combination of the higher probability weighted moments, LH-moment. Design rainfall using LH-moments following the consecutive duration were derived by the regional and at-site analysis using the observed and simulated data resulted from Monte Carlo techniques. Relative root-mean-square error (RRMSE), relative bias (RBIAS) and relative reduction (RR) in RRMSE for the design rainfall were computed and compared in the regional and at-site frequency analysis. Consequently, it was shown that the regional analysis can substantially more reduce the RRMSE, RBIAS and RR in RRMSE than at-site analysis in the prediction of design rainfall. Relative efficiency (RE) for an optimal order of L-moments was also computed by the methods of L, L1, L2, L3 and L4-moments for GEV distribution. It was found that the method of L-moments is more effective than the others for getting optimal design rainfall according to the regions and consecutive durations in the regional frequency analysis. Diagrams for the design rainfall derived by the regional frequency analysis using L-moments were drawn according to the regions and consecutive durations by GIS techniques.